Gene expression profiling in frataxin deficient mice: Microarray evidence for significant expression changes without detectable neurodegeneration

Neurobiology of Disease

Volumn 22, Issue 2, 2006, Pages 302-311

  Coppola, Giovanni ^a   Choi, Sang Hyun ^a,b   Santos, Manuela M ^c   Miranda, Carlos J ^c   Tentler, Dmitri ^a   Wexler, Eric M ^a   Pandolfo, Massimo ^d   Geschwind, Daniel H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Korea University College of Medicine   (South Korea)

^c NOTRE DAME HOSPITAL   (Canada)

^d ERASME HOSPITAL   (Belgium)

Author keywords

Frataxin; Friedreich's ataxia; Knockin knockout; Microarray; Mouse model; Neurodegeneration

Indexed keywords

FRATAXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCHEMISTRY; CELL LINE; CONTROLLED STUDY; FIBROBLAST; FRIEDREICH ATAXIA; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; MITOCHONDRION; MOUSE; NERVE DEGENERATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPINAL CORD; UNINDEXED SEQUENCE;

ANIMALS; CELL LINE; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; FEMALE; FRIEDREICH ATAXIA; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IRON-BINDING PROTEINS; MALE; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MUTATION; NERVE DEGENERATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; SPINAL CORD;

EID: 33646162871     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.11.014     Document Type: Article

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