Frataxin deficiency induces Schwann cell inflammation and death

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1792, Issue 11, 2009, Pages 1052-1061

  Lu, Chunye ^a   Schoenfeld, Robert ^a   Shan, Yuxi ^a   Tsai, Hsing Jo ^a   Hammock, Bruce ^a   Cortopassi, Gino ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Dorsal root ganglia (DRG) neuron; Frataxin; Friedreich's ataxia (FRDA); Inflammatory response; Schwann cells; siRNA

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 6 (4 FLUOROPHENYL) 2,3 DIHYDRO 5 (4 PYRIDYL)IMIDAZO[2,1 B]THIAZOLE; ACETYLCYSTEINE; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; ARACHIDONIC ACID; ARACHIDONYLTRIFLUOROMETHYLKETONE; BENZYLOXYCARBONYLPHENYLALANYLALANYL FLUOROMETHYL KETONE; BROMOENOL LACTONE; BUTYLATED HYDROXYANISOLE; BUTYLCRESOL; CYCLOOXYGENASE 2 INHIBITOR; DEFERIPRONE; DEFEROXAMINE; DEXAMETHASONE; FRATAXIN; INDOMETACIN; INTERLEUKIN 1BETA ANTIBODY; INTERLEUKIN 6 ANTIBODY; MANGANESE 5,10,15,20 TETRAKIS(4 BENZOIC ACID)PORPHYRIN; MEPACRINE; METHYLARACHIDONYLFLUOROPHOSPHONATE; NORDIHYDROGUAIARETIC ACID; PALMITOYLTRIFLUOROMETHYLKETONE; PHOSPHOLIPASE INHIBITOR; SALICYLIC ACID; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ANTIBODY; UNCLASSIFIED DRUG; UNINDEXED DRUG; IL6 PROTEIN, HUMAN; INTERLEUKIN 6; IRON BINDING PROTEIN;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG POTENCY; GENE ACTIVATION; HUMAN; HUMAN CELL; INFLAMMATION; MOUSE; NERVE CELL NECROSIS; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN DEPLETION; RAT; SCHWANN CELL; SPINAL GANGLION; CELL DEATH; CELL LINE; CELL SURVIVAL; DEMYELINATING DISEASE; GENE SILENCING; GENETICS; METABOLISM; MUTATION; NERVE CELL; PATHOLOGY;

CELL DEATH; CELL LINE; CELL SURVIVAL; GANGLIA, SPINAL; GENE KNOCKDOWN TECHNIQUES; HEREDODEGENERATIVE DISORDERS, NERVOUS SYSTEM; HUMANS; INFLAMMATION; INTERLEUKIN-6; IRON-BINDING PROTEINS; MUTATION; NEURONS; SCHWANN CELLS;

EID: 73349107807     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2009.07.011     Document Type: Article

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