Long intronic GAA•TTC repeats induce epigenetic changes and reporter gene silencing in a molecular model of Friedreich ataxia

Nucleic Acids Research

Volumn 36, Issue 19, 2008, Pages 6056-6065

  Soragni, E ^b   Herman, D ^b   Dent, S Y R ^c   Gottesfeld, J M ^b   Wells, R D ^a   Napierala, M ^a,c  

^a UNIVERSITY OF TEXAS   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FRATAXIN; GREEN FLUORESCENT PROTEIN; HISTONE; HISTONE DEACETYLASE INHIBITOR;

ACETYLATION; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; EPIGENETICS; FRIEDREICH ATAXIA; GENE EXPRESSION REGULATION; GENE INSERTION; GENE MUTATION; GENE SILENCING; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; INTRON; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN METHYLATION; REPORTER GENE; TRANSCRIPTION TERMINATION; TRINUCLEOTIDE REPEAT;

CELL LINE; DNA REPEAT EXPANSION; FRIEDREICH ATAXIA; GENE SILENCING; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HETEROCHROMATIN; HISTONES; HUMANS; INTRONS; IRON-BINDING PROTEINS; MODELS, GENETIC; MODELS, MOLECULAR; TRANSCRIPTION, GENETIC;

EID: 56049103058     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkn604     Document Type: Article

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