Interleukin-1β attenuates myofibroblast formation and extracellular matrix production in dermal and lung fibroblasts exposed to transforming growth factor-β1

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Mia, Masum M ^a   Boersema, Miriam ^a   Bank, Ruud A ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE I ALPHA 1; COLLAGEN TYPE III ALPHA 1; GELATINASE A; GELATINASE B; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE 14; MESSENGER RNA; PROCOLLAGEN LYSINE 2 OXOGLUTARATE 5 DIOXYGENASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROTEIN LYSINE 6 OXIDASE; TRANSCRIPTION FACTOR GLI1; TRANSFORMING GROWTH FACTOR BETA1; TRANSGELIN; UNCLASSIFIED DRUG; COL3A1 PROTEIN, HUMAN; GLI PROTEIN; MATRIX METALLOPROTEINASE; ONCOPROTEIN; SONIC HEDGEHOG PROTEIN; TGFB1 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN;

ADULT; ARTICLE; CELL TRANSFORMATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FIBROSIS; GENE EXPRESSION; HUMAN; HUMAN CELL; LUNG FIBROBLAST; MYOFIBROBLAST; SKIN FIBROBLAST; UPREGULATION; BIOSYNTHESIS; CELL DIFFERENTIATION; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; DRUG INTERACTION; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; LUNG; METABOLISM; SIGNAL TRANSDUCTION; SKIN;

CELL DIFFERENTIATION; COLLAGEN TYPE I; COLLAGEN TYPE III; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EXTRACELLULAR MATRIX; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEDGEHOG PROTEINS; HUMANS; INTERLEUKIN-1BETA; LUNG; MATRIX METALLOPROTEINASES; MYOFIBROBLASTS; ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; SKIN; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84898007735     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091559     Document Type: Article

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