Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal

Journal of Biological Chemistry

Volumn 283, Issue 21, 2008, Pages 14345-14354

  Shimokawa, Takashi ^a   Tostar, Ulrica ^a   Lauth, Matthias ^a   Palaniswamy, Ramesh ^a   Kasper, Maria ^a   Toftgård, Rune ^a   Zaphiropoulos, Peter G ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; CELL CULTURE; CHEMICAL ACTIVATION; GENE EXPRESSION; PHOSPHORYLATION; PORT TERMINALS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

ACTIVATION MECHANISMS; BINDING DOMAINS; CELLULAR CONTEXTS; EMBRYOGENESIS ,; ENDOGENOUS GENES; EXPRESSION LEVELS; EXPRESSION PATTERNS; FUNCTIONAL PROPERTIES; HEDGEHOG SIGNALS; HUMAN TISSUES; IN LINES; ISOFORMS; NEGATIVE REGULATORS; REGULATED KINASES; SPLICE VARIANTS; STEM CELLS; TARGET GENES; TRANSCRIPTIONAL ACTIVITIES; TUMOR CELL LINES; TUMORIGENESIS; TYROSINE PHOSPHORYLATIONS;

TRANSCRIPTION;

PROTEIN DYRK1; PROTEIN SUFU; PROTEIN TYROSINE KINASE; REPRESSOR PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; UNCLASSIFIED DRUG; DYRK KINASE; GLI1 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; TRANSCRIPTION FACTOR;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EXON; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN VARIANT; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL LINE; UPREGULATION; ALTERNATIVE RNA SPLICING; ANIMAL; CELL LINE; ENZYME SPECIFICITY; GENE DELETION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; NEOPLASM; POLYSOME; SIGNAL TRANSDUCTION;

ERINACEIDAE;

ALTERNATIVE SPLICING; ANIMALS; CELL LINE; GENE DELETION; HEDGEHOG PROTEINS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NEOPLASMS; POLYRIBOSOMES; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 47249159395     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M800299200     Document Type: Article

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