Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling

American Journal of Pathology

Volumn 173, Issue 1, 2008, Pages 57-67

  Bujak, Marcin ^a   Dobaczewski, Marcin ^a   Chatila, Khaled ^a   Mendoza, Leonardo H ^a   Li, Na ^a   Reddy, Anilkumar ^a   Frangogiannis, Nikolaos G ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; COLLAGEN; CYTOKINE; GELATINASE A; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1BETA; MESSENGER RNA; STROMELYSIN;

ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; FIBROGENESIS; GENE DISRUPTION; HEART INFARCTION; HEART VENTRICLE REMODELING; INFLAMMATION; MACROPHAGE; MOUSE; MYOFIBROBLAST; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; RNA SYNTHESIS; SIGNAL TRANSDUCTION; WOUND HEALING;

EID: 46749144616     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2008.070974     Document Type: Article

References (33)

1. Frangogiannis NG: Targeting the inflammatory response in healing myocardial infarcts. Curr Med Chem 2006, 13:1877-1893
2. Opie LH, Commerford PJ, Gersh BJ, Pfeffer MA: Controversies in ventricular remodelling. Lancet 2006, 367:356-367
3. White HD, Norris RM, Brown MA, Brandt PW, Whitlock RM, Wild CJ: Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction. Circulation 1987, 76:44-51
4. St John Sutton M, Pfeffer MA, Plappert T, Rouleau JL, Moye LA, Dagenais GR, Lamas GA, Klein M, Sussex B, Goldman S: Quantitative two-dimensional echocardiographic measurements are major predictors of adverse cardiovascular events after acute myocardial infarction. The protective effects of captopril. Circulation 1994, 89:68-75
5. Nian M, Lee P, Khaper N, Liu P: Inflammatory cytokines and post-myocardial infarction remodeling. Circ Res 2004, 94:1543-1553
6. Frangogiannis NG, Ren G, Dewald O, Zymek P, Haudek S, Koerting A, Winkelmann K, Michael LH, Lawler J, Entman ML: The critical role of endogenous thrombospondin (TSP)-1 in preventing expansion of healing myocardial infarcts. Circulation 2005, 111:2935-2942
7. Vanhoutte D, Schellings M, Pinto Y, Heymans S: Relevance of matrix metalloproteinases and their inhibitors after myocardial infarction: a temporal and spatial window. Cardiovasc Res 2006, 69:604-613
8. Sims JE, Gayle MA, Slack JL, Alderson MR, Bird TA, Giri JG, Colotta F, Re F, Mantovani A, Shanebeck K, Grabstein KH, Dower SK: Interleukin 1 signaling occurs exclusively via the type I receptor. Proc Natl Acad Sci USA 1993, 90:6155-6159
9. Colotta F, Re F, Muzio M, Bertini R, Polentarutti N, Sironi M, Giri JG, Dower SK, Sims JE, Mantovani A: Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. Science 1993, 261:472-475
10. Bourke E, Cassetti A, Villa A, Fadlon E, Colotta F, Mantovani A: IL-1 beta scavenging by the type II IL-1 decoy receptor in human neutrophils. J Immunol 2003, 170:5999-6005
11. Herskowitz A, Choi S, Ansari AA, Wesselingh S: Cytokine mRNA expression in postischemic/reperfused myocardium. Am J Pathol 1995, 146:419-428
12. Dewald O, Ren G, Duerr GD, Zoerlein M, Klemm C, Gersch C, Tincey S, Michael LH, Entman ML, Frangogiannis NG: Of mice and dogs: species-specific differences in the inflammatory response following myocardial infarction. Am J Pathol 2004, 164:665-677
13. Hwang MW, Matsumori A, Furukawa Y, Ono K, Okada M, Iwasaki A, Hara M, Miyamoto T, Touma M, Sasayama S: Neutralization of interleukin-1beta in the acute phase of myocardial infarction promotes the progression of left ventricular remodeling. J Am Coll Cardiol 2001, 38:1546-1553
14. Suzuki K, Murtuza B, Smolenski RT, Sammut IA, Suzuki N, Kaneda Y, Yacoub MH: Overexpression of interleukin-1 receptor antagonist provides cardioprotection against ischemia-reperfusion injury associated with reduction in apoptosis. Circulation 2001, 104:I308-I313
15. Labow M, Shuster D, Zetterstrom M, Nunes P, Terry R, Cullinan EB, Bartfai T, Solorzano C, Moldawer LL, Chizzonite R, McIntyre KW: Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice. J Immunol 1997, 159:2452-2461
16. Dewald O, Zymek P, Winkelmann K, Koerting A, Ren G, Abou-Khamis T, Michael LH, Rollins BJ, Entman ML, Frangogiannis NG: CCL2/monocyte chemoattractant protein-1 regulates inflammatory responses critical to healing myocardial infarcts. Circ Res 2005, 96:881-889
17. Zymek P, Bujak M, Chatila K, Cieslak A, Thakker G, Entman ML, Frangogiannis NG: The role of platelet-derived growth factor signaling in healing myocardial infarcts. J Am Coll Cardiol 2006, 48:2315-2323
18. Michael LH, Ballantyne CM, Zachariah JP, Gould KE, Pocius JS, Taffet GE, Hartley CJ, Pham TT, Daniel SL, Funk E, Entman ML: Myocardial infarction and remodeling in mice: effect of reperfusion. Am J Physiol 1999, 277:H660-H668
19. Bujak M, Ren G, Kweon HJ, Dobaczewski M, Reddy A, Taffet G, Wang XF, Frangogiannis NG: Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling. Circulation 2007, 116:2127-2138
20. Huebener P, Abou-Khamis T, Zymek P, Bujak M, Ying X, Chatila K, Haudek S, Thakker G, Frangogiannis NG: CD44 is critically involved in infarct healing by regulating the inflammatory and fibrotic response. J Immunol 2008, 180:2625-2633
21. Zymek P, Nah DY, Bujak M, Ren G, Koerting A, Leucker T, Huebener P, Taffet G, Entman M, Frangogiannis NG: Interleukin-10 is not a critical regulator of infarct healing and left ventricular remodeling. Cardiovasc Res 2007, 74:313-322
22. Frangogiannis NG, Dewald O, Xia Y, Ren G, Haudek S, Leucker T, Kraemer D, Taffet G, Rollins BJ, Entman ML: Critical role of monocyte chemoattractant protein-1/CC chemokine ligand 2 in the pathogenesis of ischemic cardiomyopathy. Circulation 2007, 115:584-592
23. Virag JI, Murry CE: Myofibroblast and endothelial cell proliferation during murine myocardial infarct repair. Am J Pathol 2003, 163:2433-2440
24. Desmoulière A, Geinoz A, Gabbiani F, Gabbiani G: Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biol 1993, 122:103-111
25. Guillén I, Blanes M, Gomez-Lechon MJ, Castell JV: Cytokine signaling during myocardial infarction: sequential appearance of IL-1 beta and IL-6. Am J Physiol 1995, 269:R229-R235
26. Kato A, Gabay C, Okaya T, Lentsch AB: Specific role of interleukin-1 in hepatic neutrophil recruitment after ischemia/reperfusion. Am J Pathol 2002, 161:1797-1803
27. Colotta F, Re F, Polentarutti N, Sozzani S, Mantovani A: Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products. Blood 1992, 80:2012-2020
28. Bujak M, Frangogiannis NG: The role of TGF-beta signaling in myocardial infarction and cardiac remodeling. Cardiovasc Res 2007, 74:184-195
29. Gurantz D, Cowling RT, Varki N, Frikovsky E, Moore CD, Greenberg BH: IL-1beta and TNF-alpha upregulate angiotensin II type 1 (AT1) receptors on cardiac fibroblasts and are associated with increased AT1 density in the post-MI heart. J Mol Cell Cardiol 2005, 38:505-515
30. Mitchell MD, Laird RE, Brown RD, Long CS: IL-1beta stimulates rat cardiac fibroblast migration via MAP kinase pathways. Am J Physiol 2007, 292:H1139-H1147
31. Siwik DA, Chang DL, Colucci WS: Interleukin-1beta and tumor necrosis factor-alpha decrease collagen synthesis and increase matrix metalloproteinase activity in cardiac fibroblasts in vitro. Circ Res 2000, 86:1259-1265
32. Berk BC, Fujiwara K, Lehoux S: ECM remodeling in hypertensive heart disease. J Clin Invest 2007, 117:568-575
33. Murtuza B, Suzuki K, Bou-Gharios G, Beauchamp JR, Smolenski RT, Partridge TA, Yacoub MH: Transplantation of skeletal myoblasts secreting an IL-1 inhibitor modulates adverse remodeling in infarcted murine myocardium. Proc Natl Acad Sci USA 2004, 101:4216 -4221