Elevated formation of pyridinoline cross-links by profibrotic cytokines is associated with enhanced lysyl hydroxylase 2b levels

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1741, Issue 1-2, 2005, Pages 95-102

  Van Der Slot, Annemarie J ^a   Van Dura, Ernst A ^a   De Wit, Elly C ^a   De Groot, Jeroen ^a   Huizinga, Tom W J ^b   Bank, Ruud A ^a   Zuurmond, Anne Marie ^a  

^a TNO   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Collagen; Cytokine; Fibrosis; Lysyl hydroxylase 2b; Pyridinoline; TGF

Indexed keywords

ACTIVIN A; COLLAGEN; COLLAGEN TYPE 1; CYTOKINE; INTERLEUKIN 4; MESSENGER RNA; PROCOLLAGEN LYSINE 2 OXOGLUTARATE 5 DIOXYGENASE; PROTEIN LYSINE 6 OXIDASE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; CROSS LINKING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN FIBROBLAST; SKIN FIBROSIS; UPREGULATION;

ACTIVINS; AMINO ACIDS; CELLS, CULTURED; COLLAGEN TYPE I; CROSS-LINKING REAGENTS; CYTOKINES; FIBROBLASTS; FIBROSIS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INHIBIN-BETA SUBUNITS; INTERLEUKIN-4; PROCOLLAGEN-LYSINE, 2-OXOGLUTARATE 5-DIOXYGENASE; PROTEIN ISOFORMS; RNA, MESSENGER; SKIN; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 20444465773     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2004.09.009     Document Type: Article

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