Interleukin-1 β and tumor necrosis factor-α decrease collagen synthesis and increase matrix metalloproteinase activity in cardiac fibroblasts in vitro

Circulation Research

Volumn 86, Issue 12, 2000, Pages 1259-1265

  Siwik, Deborah A ^a   Chang, Donny L F ^a   Colucci, Wilson S ^a,b  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BOSTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Collagen; Inflammatory cytokines; Interleukin 1 ; Matrix metalloproteinase; Tumor necrosis factor

Indexed keywords

COLLAGEN; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; INTERLEUKIN 1; NITRIC OXIDE;

ANIMAL CELL; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROBLAST CULTURE; HEART; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; RAT; RNA ANALYSIS; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DRUG ANTAGONISM; FIBROBLAST; GENETICS; HEART MUSCLE; METABOLISM; PHYSIOLOGY;

ANIMALS; CELLS, CULTURED; COLLAGEN; FIBROBLASTS; INFLAMMATION MEDIATORS; INTERLEUKIN-1; MATRIX METALLOPROTEINASES; MYOCARDIUM; NITRIC OXIDE; RATS; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034705240     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.86.12.1259     Document Type: Article

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