Curcumin attenuates inflammatory response in IL-1β-induced human synovial fibroblasts and collagen-induced arthritis in mouse model

International Immunopharmacology

Volumn 10, Issue 5, 2010, Pages 605-610

  Moon, Dong Oh ^a   Kim, Mun Ok ^a   Choi, Yung Hyun ^b   Park, Yung Min ^c   Kim, Gi Young ^a  

^a Jeju National University   (South Korea)

^b Dong Eui University   (South Korea)

^c Pusan National University School of Medicine   (South Korea)

Author keywords

Collagen induced arthritis; Curcumin; Cyclooxygenase 2; Matrix metalloproteinase; Nuclear factor B; Prostaglandin E2

Indexed keywords

CURCUMIN; CYCLOOXYGENASE 2; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G2A; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANKLE; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; FIBROBLAST; HUMAN; HUMAN CELL; INFLAMMATION; MALE; MOUSE; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNOVIOCYTE; T LYMPHOCYTE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIBODY FORMATION; ARTHRITIS, EXPERIMENTAL; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN TYPE II; CURCUMIN; CYTOKINES; DISEASE PROGRESSION; FIBROBLASTS; FREUND'S ADJUVANT; HUMANS; INTERLEUKIN-1BETA; MALE; MICE; MICE, INBRED DBA; SEVERITY OF ILLNESS INDEX; SYNOVIAL MEMBRANE; T-LYMPHOCYTES;

EID: 77950516262     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2010.02.011     Document Type: Article

References (34)

1. Feldmann M., Brennan F.M., and Maini R.N. Role of cytokines in rheumatoid arthritis. Annu Rev Immunol 14 (1996) 397-340
2. Andreakos E.T., Foxwell B.M., Brennan F.M., Maini R.N., and Feldmann M. Cytokines and anti-cytokine biologicals in autoimmunity: present and future. Cytokine Growth Factor Rev 13 (2002) 299-313
3. Goldenberg M.M. Celecoxib, a selective cyclooxygenase-2 inhibitor for the treatment of rheumatoid arthritis and osteoarthritis. Clin Ther 21 (1999) 1497-1513
4. Burger D., Begué-Pastor N., Benavent S., Gruaz L., Kaufmann M.T., Chicheportiche R., et al. The active metabolite of leflunomide, A77 1726, inhibits the production of prostaglandin E(2), matrix metalloproteinase 1 and interleukin 6 in human fibroblast-like synoviocytes. Rheumatology (Oxford) 42 (2003) 89-96
5. Nee L., Tuite N., Ryan M.P., and McMorrow T. TNF-α and IL-1β-mediated regulation of MMP-9 and TIMP-1 in human glomerular mesangial cells. Nephron Exp Nephrol 107 (2007) 73-86
6. Warren J.S. Interleukins and tumor necrosis factor in inflammation. Crit Rev Clin Lab Sci 28 (1990) 37-59
7. Wood D.D., Ihrie E.J., and Hamerman D. Release of interleukin-1 from human synovial tissue in vitro. Arthritis Rheum 28 (1985) 853-862
8. Ritchlin C. Fibroblast biology. Effector signals released by the synovial fibroblast in arthritis. Arthritis Res 2 (2000) 356-360
9. Dejardin E. The alternative NF-κB pathway from biochemistry to biology: pitfalls and promises for future drug development. Biochem Pharmacol 72 (2006) 1161-1179
10. Brown K.D., Claudio E., and Siebenlist U. The roles of the classical and alternative nuclear factor-kappaB pathways: potential implications for autoimmunity and rheumatoid arthritis. Arthritis Res Ther 10 (2008) 212
11. Roman-Blas J.A., and Jimenez S.A. NF-κB as a potential therapeutic target in osteoarthritis and rheumatoid arthritis. Osteoarthritis Cartilage 14 (2006) 839-848
12. Dieguez-Gonzalez R., Calaza M., Perez-Pampin E., Balsa A., Blanco F.J., Cañete J.D., et al. Analysis of TNFAIP3, a feedback inhibitor of nuclear factor-kappaB and the neighbor intergenic 6q23 region in rheumatoid arthritis susceptibility. Arthritis Res Ther 11 (2009) R42
13. He Y., Xu H., Liang L., Zhan Z., Yang X., Yu X., et al. Antiinflammatory effect of Rho kinase blockade via inhibition of NF-κB activation in rheumatoid arthritis. Arthritis Rheum 58 (2008) 3366-3376
14. Lee Y.R., Kweon S.H., Kwon K.B., Park J.W., Yoon T.R., and Park B.H. Inhibition of IL-1β-mediated inflammatory responses by the IκB alpha super-repressor in human fibroblast-like synoviocytes. Biochem Biophys Res Commun 378 (2009) 90-94
15. Aggarwal B.B., and Sung B. Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets. Trends Pharmacol Sci 30 (2009) 85-94
16. Aggarwal B.B., and Harikumar K.B. Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases. Int J Biochem Cell Biol 41 (2009) 40-59
17. Bright J.J. Curcumin and autoimmune disease. Adv Exp Med Biol 595 (2007) 425-451
18. Park C., Moon D.O., Choi I.W., Choi B.T., Nam T.J., Rhu C.H., et al. Curcumin induces apoptosis and inhibits prostaglandin E(2) production in synovial fibroblasts of patients with rheumatoid arthritis. Int J Mol Med 20 (2007) 365-372
19. Shakibaei M., John T., Schulze-Tanzil G., Lehmann I., and Mobasheri A. Suppression of NF-κB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: implications for the treatment of osteoarthritis. Biochem Pharmacol 73 (2007) 1434-1445
20. Alvaro-Gracia J.M., Zvaifler N.J., and Firestein G.S. Cytokines in chronic inflammatory arthritis. V. Mutual antagonism between interferon-γ and tumor necrosis factor-α on HLA-DR expression, proliferation, collagenase production, and granulocyte macrophage colony-stimulating factor production by rheumatoid arthritis synoviocytes. J Clin Invest 86 (1990) 1790-1798
21. Courtenay J.S., Dallman M.J., Dayan A.D., Martin A., and Mosedale B. Immunisation against heterologous type II collagen induces arthritis in mice. Nature 283 (1980) 666-668
22. van den Berg W.B., van Lent P.L., Joosten L.A., Abdollahi-Roodsaz S., and Koenders M.I. Amplifying elements of arthritis and joint destruction. Ann Rheum Dis 66 Suppl 3 (2007) iii45-iii48
23. Scrivo R., Di Franco M., Spadaro A., and Valesini G. The immunology of rheumatoid arthritis. Ann N Y Acad Sci 1108 (2007) 312-322
24. Siebenlist U., Franzoso G., and Brown K. Structure, regulation and function of NF-κB. Annu Rev Cell Biol 10 (1994) 405-455
25. Perkins N.D. Integrating cell-signalling pathways with NF-κB and IKK function. Nat Rev Mol Cell Biol 8 (2007) 49-62
26. Stuart J.M., Townes A.S., and Kang A.H. Collagen autoimmune arthritis. Annu Rev Immunol 2 (1984) 199-218
27. Breedveld F.C., Struyk L., van Laar J.M., Miltenburg A.M., de Vries R.R., and van den Elsen P.J. Therapeutic regulation of T cells in rheumatoid arthritis. Immunol Rev 144 (1995) 5-16
28. Bugatti S., Codullo V., Caporali R., and Montecucco C. B cells in rheumatoid arthritis. Autoimmun Rev 7 (2007) 137-142
29. Wooley P.H., Luthra H.S., Stuart J.M., and David C.S. collagen induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates. J Exp Med 154 (1981) 688-700
30. Corthay A., Johansson A., Vestberg M., and Holmdahl R. Collagen-induced arthritis development requires alpha beta T cells but not gamma delta T cells: studies with T cell-deficient (TCR mutant) mice. Int Immunol 11 (1999) 1065-1073
31. Shi J., Schmitt-Talbot E., DiMattia D.A., and Dullea R.G. The differential effects of IL-1 and TNF-α on proinflammatory cytokine and matrix metalloproteinase expression in human chondrosarcoma cells. Inflamm Res 53 (2004) 377-389
32. Kaneko M., Tomita T., Nakase T., Ohsawa Y., Seki H., Takeuchi E., et al. Expression of proteinases and inflammatory cytokines in subchondral bone regions in the destructive joint of rheumatoid arthritis. Rheumatology (Oxford) 40 (2001) 247-255
33. Konttinen Y.T., Salo T., Hanemaaijer R., Valleala H., Sorsa T., Sutinen M., et al. Collagenase-3 (MMP-13) and its activators in rheumatoid arthritis: localization in the pannus-hard tissue junction and inhibition by alendronate. Matrix Biol 18 (1999) 401-412
34. Fuchs S., Skwara A., Bloch M., and Dankbar B. Differential induction and regulation of matrix metalloproteinases in osteoarthritic tissue and fluid synovial fibroblasts. Osteoarthritis Cartilage 12 (2004) 409-418