Hedgehog-Gli pathway activation during kidney fibrosis

American Journal of Pathology

Volumn 180, Issue 4, 2012, Pages 1441-1453

  Fabian, Steven L ^a   Penchev, Radostin R ^a   St Jacques, Benoit ^b   Rao, Anjali N ^a   Sipil, Petra ^c   West, Kip A ^d   McMahon, Andrew P ^e,f,g   Humphreys, Benjamin D ^a,e  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^c UNIVERSITY OF TURKU   (Finland)

^d Infinity Pharmaceuticals Inc   (United States)

^e HARVARD STEM CELL INSTITUTE   (United States)

^f Harvard University   (United States)

^g HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CYCLOPAMINE; IPI 926; KI 67 ANTIGEN; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN PATCHED 1; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; DISEASE COURSE; FIBROBLAST; IN VIVO STUDY; KIDNEY FIBROSIS; KIDNEY TUBULE CELL; MOUSE; MYOFIBROBLAST; NONHUMAN; PARACRINE SIGNALING; PERICYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; CELL LINE; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; FIBROBLASTS; FIBROSIS; HEDGEHOG PROTEINS; KIDNEY; KIDNEY TUBULES; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LIGANDS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; PARACRINE COMMUNICATION; PERICYTES; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; UP-REGULATION; VERATRUM ALKALOIDS;

EID: 84859015834     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.12.039     Document Type: Article

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