-
1
-
-
42949089442
-
Exenatide and rare adverse events
-
(discussion, 1971-1972)
-
Ahmad SR & Swann J 2008 Exenatide and rare adverse events. New England Journal of Medicine 358 1971-1972 (discussion 1971-1972)
-
(2008)
New England Journal of Medicine
, vol.358
, pp. 1971-1972
-
-
Ahmad, S.R.1
Swann, J.2
-
3
-
-
41149141306
-
Toomuch of a good thing: why it is bad to stimulate the b cell to secrete insulin
-
Aston-Mourney K, Proietto J, Morahan G & Andrikopoulos S 2008 Toomuch of a good thing: why it is bad to stimulate the b cell to secrete insulin Diabetologia 51 540-545
-
(2008)
Diabetologia
, vol.51
, pp. 540-545
-
-
Aston-Mourney, K.1
Proietto, J.2
Morahan, G.3
Andrikopoulos, S.4
-
4
-
-
84881652869
-
One year of sitagliptin treatment protects against islet amyloid-associated β-cells loss and does not induce pancreatitis or pancreatic neoplasia in mice
-
Aston-Mourney K, Subramanian SL, Zraika S, Samarasekera T, Meier DT, Goldstein LC & Hull RL 2013 One year of sitagliptin treatment protects against islet amyloid-associated β-cells loss and does not induce pancreatitis or pancreatic neoplasia in mice. American Journal of Physiology. Endocrinology and Metabolism 305 E475-E484
-
(2013)
American Journal of Physiology. Endocrinology and Metabolism
, vol.305
-
-
Aston-Mourney, K.1
Subramanian, S.L.2
Zraika, S.3
Samarasekera, T.4
Meier, D.T.5
Goldstein, L.C.6
Hull, R.L.7
-
5
-
-
41349098117
-
An albumin-exendin-4 conjugate engages central and peripheral circuits regulating murine energy and glucose homeostasis
-
Baggio LL, Huang Q, Cao X & Drucker DJ 2008 An albumin-exendin-4 conjugate engages central and peripheral circuits regulating murine energy and glucose homeostasis. Gastroenterology 134 1137-1147
-
(2008)
Gastroenterology
, vol.134
, pp. 1137-1147
-
-
Baggio, L.L.1
Huang, Q.2
Cao, X.3
Drucker, D.J.4
-
6
-
-
0347125292
-
The endocrine pancreas in nondiabetic rats after short-term and long-term treatment with the longacting GLP-1 derivative NN2211
-
Bock T, Pakkenberg B & Buschard K 2003 The endocrine pancreas in nondiabetic rats after short-term and long-term treatment with the longacting GLP-1 derivative NN2211. APMIS 111 1117-1124
-
(2003)
APMIS
, vol.111
, pp. 1117-1124
-
-
Bock, T.1
Pakkenberg, B.2
Buschard, K.3
-
7
-
-
0020636495
-
Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release
-
Bonner-Weir S, Trent DF & Weir GC 1983 Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release. Journal of Clinical Investigation 71 1544-1553
-
(1983)
Journal of Clinical Investigation
, vol.71
, pp. 1544-1553
-
-
Bonner-Weir, S.1
Trent, D.F.2
Weir, G.C.3
-
8
-
-
84903183754
-
analysis of study of pancreatic effects of incretin therapy: methodological deficiencies
-
[in press]
-
Bonner-Weir S, In't Veld P & Weir G 2014 Re-analysis of study of pancreatic effects of incretin therapy: methodological deficiencies. Diabetes, Obesity & Metabolism [in press]
-
(2014)
Diabetes, Obesity & Metabolism
-
-
Bonner-Weir, S.1
In't Veld, P.2
Weir, G.3
-
9
-
-
80054090833
-
Effects of exenatide on measures of β-cells function after, 3 years in metformin-treated patients with type 2 diabetes
-
Bunck MC, Corner A, Eliasson B, Heine RJ, Shaginian RM, Taskinen MR, Smith U, Yki-Jarvinen H & DiamantM 2011 Effects of exenatide on measures of β-cells function after 3 years in metformin-treated patients with type 2 diabetes. Diabetes Care 34 2041-2047
-
(2011)
Diabetes Care
, vol.34
, pp. 2041-2047
-
-
Bunck, M.C.1
Corner, A.2
Eliasson, B.3
Heine, R.J.4
Shaginian, R.M.5
Taskinen, M.R.6
Smith, U.7
Yki-Jarvinen, H.8
Diamant, M.9
-
10
-
-
84871138390
-
Studies in rodents with the dipeptidyl peptidase-4 inhibitor vildagliptin to evaluate possible drug-induced pancreatic histological changes that are predictive of pancreatitis and cancer development in man. Diabetes
-
Busch SJ, Hoffmann P, Sahota P, Johnson R, KothnyW, Meyer F & Foley JE 2013 Studies in rodents with the dipeptidyl peptidase-4 inhibitor vildagliptin to evaluate possible drug-induced pancreatic histological changes that are predictive of pancreatitis and cancer development in man. Diabetes, Obesity & Metabolism 15 72-76
-
(2013)
Obesity & Metabolism
, vol.15
, pp. 72-76
-
-
Busch, S.J.1
Hoffmann, P.2
Sahota, P.3
Johnson, R.4
Kothny, W.5
Meyer, F.6
Foley, J.E.7
-
11
-
-
33745315716
-
Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic β-cells mass
-
Buteau J, Spatz ML & Accili D 2006 Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic β-cells mass. Diabetes 55 1190-1196
-
(2006)
Diabetes
, vol.55
, pp. 1190-1196
-
-
Buteau, J.1
Spatz, M.L.2
Accili, D.3
-
12
-
-
2542581025
-
Diabetes due to a progressive defect in β-cells mass in rats transgenic for human islet amyloid polypeptide (HIP rat): a new model for type 2 diabetes
-
Butler AE, Jang J, Gurlo T, Carty MD, SoellerWC & Butler PC 2004 Diabetes due to a progressive defect in β-cells mass in rats transgenic for human islet amyloid polypeptide (HIP rat): a new model for type 2 diabetes Diabetes 53 1509-1516
-
(2004)
Diabetes
, vol.53
, pp. 1509-1516
-
-
Butler, A.E.1
Jang, J.2
Gurlo, T.3
Carty, M.D.4
Soeller, W.C.5
Butler, P.C.6
-
13
-
-
84878352363
-
Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors
-
Butler AE, Campbell-Thompson M, Gurlo T, Dawson DW, Atkinson M & Butler PC 2013 Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors. Diabetes 62 2595-2604
-
(2013)
Diabetes
, vol.62
, pp. 2595-2604
-
-
Butler, A.E.1
Campbell-Thompson, M.2
Gurlo, T.3
Dawson, D.W.4
Atkinson, M.5
Butler, P.C.6
-
14
-
-
84897887966
-
Occurrence of spontaneous pancreatic lesions in normal and diabetic rats: a potential confounding factor inthenonclinical assessmentofglucagon-likepeptide (GLP)-1-based therapies
-
[in press]
-
Chadwick KD, Fletcher AM, ParrulaMC, Bonner-Weir S,Mangipudy RS, Janovitz E, Graziano MJ, Roy D & Reilly TP 2013 Occurrence of spontaneous pancreatic lesions in normal and diabetic rats: a potential confounding factor inthenonclinical assessmentofglucagon-likepeptide (GLP)-1-based therapies. Diabetes [in press]
-
(2013)
Diabetes
-
-
Chadwick, K.D.1
Fletcher, A.M.2
Parrula, M.C.3
Bonner-Weir, S.4
Mangipudy, R.S.5
Janovitz, E.6
Graziano, M.J.7
Roy, D.8
Reilly, T.P.9
-
15
-
-
0018139377
-
Obese and diabetes: two mutant genes causing diabetes- obesity syndromes in mice
-
Coleman DL 1978 Obese and diabetes: two mutant genes causing diabetes- obesity syndromes in mice. Diabetologia 14 141-148
-
(1978)
Diabetologia
, vol.14
, pp. 141-148
-
-
Coleman, D.L.1
-
16
-
-
78751490442
-
β-cells dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptideinduced UCH-L1 deficiency
-
Costes S, Huang CJ, Gurlo T, Daval M,Matveyenko AV, Rizza RA, Butler AE & Butler PC 2011 β-cells dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptideinduced UCH-L1 deficiency. Diabetes 60 227-238
-
(2011)
Diabetes
, vol.60
, pp. 227-238
-
-
Costes, S.1
Huang, C.J.2
Gurlo, T.3
Daval, M.4
Matveyenko, A.V.5
Rizza, R.A.6
Butler, A.E.7
Butler, P.C.8
-
17
-
-
84860807644
-
Incretin-based therapy and the quest for sustained improvements in β-cells health
-
Drucker DJ 2011 Incretin-based therapy and the quest for sustained improvements in β-cells health. Diabetes Care 34 2133-2135
-
(2011)
Diabetes Care
, vol.34
, pp. 2133-2135
-
-
Drucker, D.J.1
-
18
-
-
84884583757
-
Incretin action in the pancreas: potential promise, possible perils, and pathological pitfalls
-
Drucker DJ 2013 Incretin action in the pancreas: potential promise, possible perils, and pathological pitfalls. Diabetes 62 3316-3323
-
(2013)
Diabetes
, vol.62
, pp. 3316-3323
-
-
Drucker, D.J.1
-
19
-
-
58149465731
-
Acute dipeptidyl peptidase-4 inhibition rapidly enhances insulinmediated suppression of endogenous glucose production in mice
-
Duez H, Smith AC, Xiao C, Giacca A, Szeto L, Drucker DJ & Lewis GF 2009 Acute dipeptidyl peptidase-4 inhibition rapidly enhances insulinmediated suppression of endogenous glucose production in mice Endocrinology 150 56-62
-
(2009)
Endocrinology
, vol.150
, pp. 56-62
-
-
Duez, H.1
Smith, A.C.2
Xiao, C.3
Giacca, A.4
Szeto, L.5
Drucker, D.J.6
Lewis, G.F.7
-
20
-
-
78651101398
-
The DPP-4 inhibitor vildagliptin increases pancreatic b cell mass in neonatal rats
-
Duttaroy A,Voelker F,MerriamK,ZhangX,RenX, SubramanianK,HughesTE & Burkey BF 2011 The DPP-4 inhibitor vildagliptin increases pancreatic b cell mass in neonatal rats. European Journal of Pharmacology 650 703-707
-
(2011)
European Journal of Pharmacology
, vol.650
, pp. 703-707
-
-
Duttaroy, A.1
Voelker, F.2
Merriam, K.3
Zhang, X.4
Ren, X.5
Subramanian, K.6
Hughes, T.E.7
Burkey, B.F.8
-
21
-
-
79959559653
-
Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies
-
Elashoff M, Matveyenko AV, Gier B, Elashoff R & Butler PC 2011 Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies. Gastroenterology 141 150-156
-
(2011)
Gastroenterology
, vol.141
, pp. 150-156
-
-
Elashoff, M.1
Matveyenko, A.V.2
Gier, B.3
Elashoff, R.4
Butler, P.C.5
-
22
-
-
84881612495
-
Glucagonlike peptide-1 receptor agonist treatment reduces b cell mass in normoglycaemic mice
-
Ellenbroek JH, Tons HA, Westerouen van Meeteren MJ, de Graaf N, Hanegraaf MA, Rabelink TJ, Carlotti F & de Koning EJ 2013 Glucagonlike peptide-1 receptor agonist treatment reduces b cell mass in normoglycaemic mice. Diabetologia 56 1980-1986
-
(2013)
Diabetologia
, vol.56
, pp. 1980-1986
-
-
Ellenbroek, J.H.1
Tons, H.A.2
Westerouen van Meeteren, M.J.3
de Graaf, N.4
Hanegraaf, M.A.5
Rabelink, T.J.6
Carlotti, F.7
de Koning, E.J.8
-
23
-
-
84878352363
-
Comment on: Butler et al Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors
-
Diabetes 62 2013 e18
-
Engel SS, Golm GT & Lauring B 2013 Comment on: Butler et al. Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors. Diabetes 2013;62:2595-2604. Diabetes 62 e18
-
(2013)
Diabetes
, vol.62
, pp. 2595-2604
-
-
Engel, S.S.1
Golm, G.T.2
Lauring, B.3
-
24
-
-
0036828227
-
Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats
-
Farilla L, Hui H, Bertolotto C, Kang E, Bulotta A, Di Mario U & Perfetti R 2002 Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats. Endocrinology 143 4397-4408
-
(2002)
Endocrinology
, vol.143
, pp. 4397-4408
-
-
Farilla, L.1
Hui, H.2
Bertolotto, C.3
Kang, E.4
Bulotta, A.5
Di Mario, U.6
Perfetti, R.7
-
25
-
-
0035042679
-
β-cells mass dynamics in Zucker diabetic fatty rats Rosiglitazone prevents the rise in net cell death
-
Finegood DT, McArthur MD, Kojwang D, Thomas MJ, Topp BG, Leonard T & Buckingham RE 2001 β-cells mass dynamics in Zucker diabetic fatty rats, Rosiglitazone prevents the rise in net cell death. Diabetes 50 1021-1029
-
(2001)
Diabetes
, vol.50
, pp. 1021-1029
-
-
Finegood, D.T.1
McArthur, M.D.2
Kojwang, D.3
Thomas, M.J.4
Topp, B.G.5
Leonard, T.6
Buckingham, R.E.7
-
26
-
-
84874631463
-
GLP-1 based agents and acute pancreatitis: drug safety falls victim to the three monkey paradigm
-
Gale EA 2013 GLP-1 based agents and acute pancreatitis: drug safety falls victim to the three monkey paradigm. BMJ 346 f1263.
-
(2013)
BMJ
, vol.346
-
-
Gale, E.A.1
-
27
-
-
79951906623
-
Liraglutide, a once-daily human glucagon-like peptide, 1 analogue, provides sustained improvements in glycaemic control and weight for, 2 years as monotherapy compared with glimepiride in patients with type, 2 diabetes
-
Garber A, Henry RR, Ratner R, Hale P, Chang CT, Bode B & Group L-S 2011 Liraglutide, a once-daily human glucagon-like peptide 1 analogue, provides sustained improvements in glycaemic control and weight for 2 years as monotherapy compared with glimepiride in patients with type 2 diabetes. Diabetes, Obesity & Metabolism 13 348-356
-
(2011)
Diabetes, Obesity & Metabolism
, vol.13
, pp. 348-356
-
-
Garber, A.1
Henry, R.R.2
Ratner, R.3
Hale, P.4
Chang, C.T.5
Bode, B.6
Group, L.-S.7
-
28
-
-
15444380712
-
Exenatide (exendin-4) improves insulin sensitivity and β-cell mass in insulin-resistant obese fa/fa Zucker rats independent of glycemia and body weight
-
Gedulin BR, Nikoulina SE, Smith PA, Gedulin G, Nielsen LL, Baron AD, Parkes DG & Young AA 2005 Exenatide (exendin-4) improves insulin sensitivity and β-cell mass in insulin-resistant obese fa/fa Zucker rats independent of glycemia and body weight. Endocrinology 146 2069-2076.
-
(2005)
Endocrinology
, vol.146
, pp. 2069-2076
-
-
Gedulin, B.R.1
Nikoulina, S.E.2
Smith, P.A.3
Gedulin, G.4
Nielsen, L.L.5
Baron, A.D.6
Parkes, D.G.7
Young, A.A.8
-
29
-
-
84876043035
-
Glucagon-like peptide, 1-based drugs and pancreatitis: clarity at last, but what about pancreatic cancer?
-
Gier B & Butler PC 2013 Glucagon-like peptide 1-based drugs and pancreatitis: clarity at last, but what about pancreatic cancer? JAMA Internal Medicine 173 539-541
-
(2013)
JAMA Internal Medicine
, vol.173
, pp. 539-541
-
-
Gier, B.1
Butler, P.C.2
-
30
-
-
84860567470
-
Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model
-
Gier B, Matveyenko AV, Kirakossian D, Dawson D, Dry SM & Butler PC 2012 Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model. Diabetes 61 1250-1262
-
(2012)
Diabetes
, vol.61
, pp. 1250-1262
-
-
Gier, B.1
Matveyenko, A.V.2
Kirakossian, D.3
Dawson, D.4
Dry, S.M.5
Butler, P.C.6
-
31
-
-
77955016889
-
2010Patientswithtype2 diabetesmellitushavehigher risk for acute pancreatitis compared with those without diabetes
-
Girman CJ, Kou TD,Cai B, AlexanderCM, O'Neill EA, Williams-HermanDE& KatzL2010Patientswithtype2 diabetesmellitushavehigher risk for acute pancreatitis compared with those without diabetes. Diabetes, Obesity & Metabolism 12 766-771
-
Diabetes, Obesity & Metabolism
, vol.12
, pp. 766-771
-
-
Girman, C.J.1
Kou, T.D.2
Cai, B.3
Alexander, C.M.4
O'Neill, E.A.5
Williams-Herman, D.E.6
Katz, L.7
-
32
-
-
79955821979
-
Effect of sitagliptin plus metformin on β-cells function, islet integrity and islet gene expression in Zucker diabetic fatty rats
-
Han SJ, Choi SE, Kang Y, Jung JG, Yi SA, Kim HJ, Lee KW & Kim DJ 2011 Effect of sitagliptin plus metformin on β-cells function, islet integrity and islet gene expression in Zucker diabetic fatty rats. Diabetes Research and Clinical Practice 92 213-222
-
(2011)
Diabetes Research and Clinical Practice
, vol.92
, pp. 213-222
-
-
Han, S.J.1
Choi, S.E.2
Kang, Y.3
Jung, J.G.4
Yi, S.A.5
Kim, H.J.6
Lee, K.W.7
Kim, D.J.8
-
33
-
-
84882254410
-
An analysis of characteristics of subjects examined for incretin effects on pancreatic pathology
-
Harja E, Lord J & Skyler JS 2013 An analysis of characteristics of subjects examined for incretin effects on pancreatic pathology. Diabetes Technology & Therapeutics 15 609-618
-
(2013)
Diabetes Technology & Therapeutics
, vol.15
, pp. 609-618
-
-
Harja, E.1
Lord, J.2
Skyler, J.S.3
-
34
-
-
84878352363
-
Comment on: Butler et al Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors
-
Diabetes 62 e16-e17
-
Heine RJ, Fu H, Kendall DM & Moller DE 2013 Comment on: Butler et al Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors Diabetes 2013;62:2595-2604. Diabetes 62 e16-e17
-
(2013)
Diabetes
, vol.62
, pp. 2595-2604
-
-
Heine, R.J.1
Fu, H.2
Kendall, D.M.3
Moller, D.E.4
-
35
-
-
34547638958
-
High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated β-cells apoptosis, a characteristic of humans with type, 2 but not type, 1 diabetes
-
Huang CJ, Lin CY, Haataja L, Gurlo T, Butler AE, Rizza RA & Butler PC 2007 High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated β-cells apoptosis, a characteristic of humans with type 2 but not type 1 diabetes. Diabetes 56 2016-2027
-
(2007)
Diabetes
, vol.56
, pp. 2016-2027
-
-
Huang, C.J.1
Lin, C.Y.2
Haataja, L.3
Gurlo, T.4
Butler, A.E.5
Rizza, R.A.6
Butler, P.C.7
-
36
-
-
0037386156
-
Glucagon-like peptide-1 inhibits apoptosis of insulin-secreting cells via a cyclic, 50-adenosine monophosphate-dependent protein kinase A- and a phosphatidylinositol 3-kinase-dependent pathway
-
Hui H, Nourparvar A, Zhao X & Perfetti R 2003 Glucagon-like peptide-1 inhibits apoptosis of insulin-secreting cells via a cyclic 50-adenosine monophosphate-dependent protein kinase A- and a phosphatidylinositol 3-kinase-dependent pathway. Endocrinology 144 1444-1455
-
(2003)
Endocrinology
, vol.144
, pp. 1444-1455
-
-
Hui, H.1
Nourparvar, A.2
Zhao, X.3
Perfetti, R.4
-
37
-
-
0037315790
-
Increased dietary fat promotes islet amyloid formation and β-cells secretory dysfunction in a transgenic mouse model of islet amyloid
-
Hull RL, Andrikopoulos S, Verchere CB, Vidal J, Wang F, Cnop M, Prigeon RL & Kahn SE 2003 Increased dietary fat promotes islet amyloid formation and β-cells secretory dysfunction in a transgenic mouse model of islet amyloid. Diabetes 52 372-379
-
(2003)
Diabetes
, vol.52
, pp. 372-379
-
-
Hull, R.L.1
Andrikopoulos, S.2
Verchere, C.B.3
Vidal, J.4
Wang, F.5
Cnop, M.6
Prigeon, R.L.7
Kahn, S.E.8
-
38
-
-
67349160220
-
Amyloid formation in human IAPP transgenic mouse islets and pancreas, and human pancreas, is not associated with endoplasmic reticulum stress
-
Hull RL, Zraika S, Udayasankar J, Aston-Mourney K, Subramanian SL & Kahn SE 2009 Amyloid formation in human IAPP transgenic mouse islets and pancreas, and human pancreas, is not associated with endoplasmic reticulum stress. Diabetologia 52 1102-1111
-
(2009)
Diabetologia
, vol.52
, pp. 1102-1111
-
-
Hull, R.L.1
Zraika, S.2
Udayasankar, J.3
Aston-Mourney, K.4
Subramanian, S.L.5
Kahn, S.E.6
-
39
-
-
84865007305
-
Effects of long-term treatment with the dipeptidyl peptidase-4 inhibitor vildagliptin on islet endocrine cells in non-obese type 2 diabetic Goto-Kakizaki rats
-
Inaba W, Mizukami H, Kamata K, Takahashi K, Tsuboi K & Yagihashi S 2012 Effects of long-term treatment with the dipeptidyl peptidase-4 inhibitor vildagliptin on islet endocrine cells in non-obese type 2 diabetic Goto-Kakizaki rats. European Journal of Pharmacology 691 297-306
-
(2012)
European Journal of Pharmacology
, vol.691
, pp. 297-306
-
-
Inaba, W.1
Mizukami, H.2
Kamata, K.3
Takahashi, K.4
Tsuboi, K.5
Yagihashi, S.6
-
40
-
-
84880091008
-
Incretin therapy and islet pathology: a time for caution
-
Kahn SE 2013 Incretin therapy and islet pathology: a time for caution Diabetes 62 2178-2180
-
(2013)
Diabetes
, vol.62
, pp. 2178-2180
-
-
Kahn, S.E.1
-
41
-
-
0037339649
-
Development and characterization of a glucagonlike peptide, 1-albumin conjugate: the ability to activate the glucagonlike peptide 1 receptor in vivo
-
KimJG, Baggio LL, Bridon DP, Castaigne JP, Robitaille MF, Jette L, Benquet C & Drucker DJ 2003 Development and characterization of a glucagonlike peptide 1-albumin conjugate: the ability to activate the glucagonlike peptide 1 receptor in vivo. Diabetes 52 751-759
-
(2003)
Diabetes
, vol.52
, pp. 751-759
-
-
Kim, J.G.1
Baggio, L.L.2
Bridon, D.P.3
Castaigne, J.P.4
Robitaille, M.F.5
Jette, L.6
Benquet, C.7
Drucker, D.J.8
-
42
-
-
70349120958
-
Glucagon-like peptide-1 receptor activation modulates pancreatitis-associated gene expression but does not modify the susceptibility to experimental pancreatitis in mice
-
Koehler JA, Baggio LL, Lamont BJ, Ali S & Drucker DJ 2009 Glucagon-like peptide-1 receptor activation modulates pancreatitis-associated gene expression but does not modify the susceptibility to experimental pancreatitis in mice. Diabetes 58 2148-2161
-
(2009)
Diabetes
, vol.58
, pp. 2148-2161
-
-
Koehler, J.A.1
Baggio, L.L.2
Lamont, B.J.3
Ali, S.4
Drucker, D.J.5
-
43
-
-
74849108033
-
Exendin-4 potentiates insulinotropic action partly via increasing β-cells proliferation and neogenesis and decreasing apoptosis in association with the attenuation of endoplasmic reticulum stress in islets of diabetic rats
-
Kwon DY, Kim YS, Ahn IS, Kim da S, Kang S, Hong SM & Park S 2009 Exendin-4 potentiates insulinotropic action partly via increasing β-cells proliferation and neogenesis and decreasing apoptosis in association with the attenuation of endoplasmic reticulum stress in islets of diabetic rats. Journal of Pharmacological Sciences 111 361-371
-
(2009)
Journal of Pharmacological Sciences
, vol.111
, pp. 361-371
-
-
Kwon, D.Y.1
Kim, Y.S.2
Ahn, I.S.3
Kim da, S.4
Kang, S.5
Hong, S.M.6
Park, S.7
-
44
-
-
38449111196
-
Differential antidiabetic efficacy of incretin agonists versus DPP-4 inhibition in high fat fed mice
-
Lamont BJ & Drucker DJ 2008 Differential antidiabetic efficacy of incretin agonists versus DPP-4 inhibition in high fat fed mice. Diabetes 57 190-198
-
(2008)
Diabetes
, vol.57
, pp. 190-198
-
-
Lamont, B.J.1
Drucker, D.J.2
-
45
-
-
84855465547
-
Pancreatic GLP-1 receptor activation is sufficient for incretin control of glucose metabolism in mice
-
Lamont BJ, Li Y, Kwan E, Brown TJ, Gaisano H & Drucker DJ 2012 Pancreatic GLP-1 receptor activation is sufficient for incretin control of glucose metabolism in mice. Journal of Clinical Investigation 122 388-402
-
(2012)
Journal of Clinical Investigation
, vol.122
, pp. 388-402
-
-
Lamont, B.J.1
Li, Y.2
Kwan, E.3
Brown, T.J.4
Gaisano, H.5
Drucker, D.J.6
-
46
-
-
84876788888
-
Models of acute and chronic pancreatitis
-
Lerch MM & Gorelick FS 2013 Models of acute and chronic pancreatitis Gastroenterology 144 1180-1193
-
(2013)
Gastroenterology
, vol.144
, pp. 1180-1193
-
-
Lerch, M.M.1
Gorelick, F.S.2
-
47
-
-
0037414781
-
Glucagon-like peptide-1 receptor signaling modulates b cell apoptosis
-
Li Y, Hansotia T, Yusta B, Ris F, Halban PA & Drucker DJ 2003 Glucagon-like peptide-1 receptor signaling modulates b cell apoptosis. Journal of Biological Chemistry 278 471-478
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 471-478
-
-
Li, Y.1
Hansotia, T.2
Yusta, B.3
Ris, F.4
Halban, P.A.5
Drucker, D.J.6
-
48
-
-
12744259876
-
β-cells Pdx1 expression is essential for the glucoregulatory, proliferative, and cytoprotective actions of glucagon-like peptide-1
-
Li Y, Cao X, Li LX, Brubaker PL, Edlund H & Drucker DJ 2005 β-cells Pdx1 expression is essential for the glucoregulatory, proliferative, and cytoprotective actions of glucagon-like peptide-1. Diabetes 54 482-491
-
(2005)
Diabetes
, vol.54
, pp. 482-491
-
-
Li, Y.1
Cao, X.2
Li, L.X.3
Brubaker, P.L.4
Edlund, H.5
Drucker, D.J.6
-
50
-
-
12244287074
-
Sulfonylurea induced β-cells apoptosis in cultured human islets
-
Maedler K, Carr RD, Bosco D, Zuellig RA, Berney T & Donath MY 2005 Sulfonylurea induced β-cells apoptosis in cultured human islets Journal of Clinical Endocrinology and Metabolism 90 501-506
-
(2005)
Journal of Clinical Endocrinology and Metabolism
, vol.90
, pp. 501-506
-
-
Maedler, K.1
Carr, R.D.2
Bosco, D.3
Zuellig, R.A.4
Berney, T.5
Donath, M.Y.6
-
51
-
-
70649094346
-
Differential importance of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide 1 receptor signaling for β cell survival in mice
-
Maida A, Hansotia T, Longuet C, Seino Y & Drucker DJ 2009 Differential importance of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide 1 receptor signaling for b cell survival in mice Gastroenterology 137 2146-2157
-
(2009)
Gastroenterology
, vol.137
, pp. 2146-2157
-
-
Maida, A.1
Hansotia, T.2
Longuet, C.3
Seino, Y.4
Drucker, D.J.5
-
52
-
-
78650950131
-
Sitagliptin prevents the development of metabolic and hormonal disturbances, increased β-cells apoptosis and liver steatosis induced by a fructose-rich diet in normal rats
-
Maiztegui B, Borelli MI, Madrid VG, Del Zotto H, Raschia MA, Francini F, Massa ML, Flores LE, Rebolledo OR & Gagliardino JJ 2011 Sitagliptin prevents the development of metabolic and hormonal disturbances, increased β-cells apoptosis and liver steatosis induced by a fructose-rich diet in normal rats. Clinical Science 120 73-80
-
(2011)
Clinical Science
, vol.120
, pp. 73-80
-
-
Maiztegui, B.1
Borelli, M.I.2
Madrid, V.G.3
Del Zotto, H.4
Raschia, M.A.5
Francini, F.6
Massa, M.L.7
Flores, L.E.8
Rebolledo, O.R.9
Gagliardino, J.J.10
-
53
-
-
33747055111
-
β-cells deficit due to increased apoptosis in the human islet amyloid polypeptide transgenic (HIP) rat recapitulates the metabolic defects present in type 2 diabetes
-
Matveyenko AV & Butler PC 2006 β-cells deficit due to increased apoptosis in the human islet amyloid polypeptide transgenic (HIP) rat recapitulates the metabolic defects present in type 2 diabetes. Diabetes 55 2106-2114
-
(2006)
Diabetes
, vol.55
, pp. 2106-2114
-
-
Matveyenko, A.V.1
Butler, P.C.2
-
54
-
-
67650245531
-
Beneficial endocrine but adverse exocrine effects of sitagliptin in the human islet amyloid polypeptide transgenic rat model of type 2 diabetes: interactions with metformin
-
Matveyenko AV, Dry S, CoxHI, Moshtaghian A,Gurlo T, Galasso R, Butler AE & Butler PC 2009 Beneficial endocrine but adverse exocrine effects of sitagliptin in the human islet amyloid polypeptide transgenic rat model of type 2 diabetes: interactions with metformin. Diabetes 58 1604-1615
-
(2009)
Diabetes
, vol.58
, pp. 1604-1615
-
-
Matveyenko, A.V.1
Dry, S.2
Cox, H.I.3
Moshtaghian, A.4
Gurlo, T.5
Galasso, R.6
Butler, A.E.7
Butler, P.C.8
-
55
-
-
0029583378
-
β-cells mass depletion precedes the onset of hyperglycaemia in the GK rat, a genetic model of non-insulindependent diabetes mellitus
-
Movassat J, Saulnier C & Portha B 1995 β-cells mass depletion precedes the onset of hyperglycaemia in the GK rat, a genetic model of non-insulindependent diabetes mellitus. Diabetes & Metabolism 21 365-370
-
(1995)
Diabetes & Metabolism
, vol.21
, pp. 365-370
-
-
Movassat, J.1
Saulnier, C.2
Portha, B.3
-
56
-
-
33748331194
-
Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic β-cells mass and function in a rodent model of type 2 diabetes
-
Mu J, Woods J, Zhou YP, Roy RS, Li Z, Zycband E, Feng Y, Zhu L, Li C, Howard AD et al. 2006 Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic β-cells mass and function in a rodent model of type 2 diabetes. Diabetes 55 1695-1704
-
(2006)
Diabetes
, vol.55
, pp. 1695-1704
-
-
Mu, J.1
Woods, J.2
Zhou, Y.P.3
Roy, R.S.4
Li, Z.5
Zycband, E.6
Feng, Y.7
Zhu, L.8
Li, C.9
Howard, A.D.10
-
57
-
-
70350203952
-
Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes
-
Mu J, Petrov A, Eiermann GJ, Woods J, Zhou YP, Li Z, Zycband E, Feng Y, Zhu L, Roy RS et al. 2009 Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes. European Journal of Pharmacology 623 148-154
-
(2009)
European Journal of Pharmacology
, vol.623
, pp. 148-154
-
-
Mu, J.1
Petrov, A.2
Eiermann, G.J.3
Woods, J.4
Zhou, Y.P.5
Li, Z.6
Zycband, E.7
Feng, Y.8
Zhu, L.9
Roy, R.S.10
-
58
-
-
72449157026
-
Biochemical and histological effects of exendin-4 (exenatide) on the rat pancreas
-
Nachnani JS, Bulchandani DG, Nookala A, Herndon B,Molteni A, Pandya P, Taylor R, Quinn T, Weide L & Alba LM 2010 Biochemical and histological effects of exendin-4 (exenatide) on the rat pancreas Diabetologia 53 153-159
-
(2010)
Diabetologia
, vol.53
, pp. 153-159
-
-
Nachnani, J.S.1
Bulchandani, D.G.2
Nookala, A.3
Herndon, B.4
Molteni, A.5
Pandya, P.6
Taylor, R.7
Quinn, T.8
Weide, L.9
Alba, L.M.10
-
59
-
-
84879231610
-
A critical analysis of the clinical use of incretin-based therapies: the benefits by far outweigh the potential risks
-
Nauck MA 2013 A critical analysis of the clinical use of incretin-based therapies: the benefits by far outweigh the potential risks. Diabetes Care 36 2126-2132
-
(2013)
Diabetes Care
, vol.36
, pp. 2126-2132
-
-
Nauck, M.A.1
-
60
-
-
65949111736
-
Increased risk of acute pancreatitis and biliary disease observed in patients with type 2 diabetes: a retrospective cohort study
-
Noel RA, Braun DK, Patterson RE & Bloomgren GL 2009 Increased risk of acute pancreatitis and biliary disease observed in patients with type 2 diabetes: a retrospective cohort study. Diabetes Care 32 834-838
-
(2009)
Diabetes Care
, vol.32
, pp. 834-838
-
-
Noel, R.A.1
Braun, D.K.2
Patterson, R.E.3
Bloomgren, G.L.4
-
61
-
-
84860577431
-
The human GLP-1 analog liraglutide and the pancreas: evidence for the absence of structural pancreatic changes in three species
-
Nyborg NC, Molck AM, Madsen LW & Knudsen LB 2012 The human GLP-1 analog liraglutide and the pancreas: evidence for the absence of structural pancreatic changes in three species. Diabetes 61 1243-1249
-
(2012)
Diabetes
, vol.61
, pp. 1243-1249
-
-
Nyborg, N.C.1
Molck, A.M.2
Madsen, L.W.3
Knudsen, L.B.4
-
62
-
-
84879914429
-
Enhanced β cell function and anti-inflammatory effect after chronic treatment with the dipeptidyl peptidase-4 inhibitor vildagliptin in an advanced-aged diet-induced obesity mouse model
-
Omar BA, Vikman J, Winzell MS, Voss U, Ekblad E, Foley JE & Ahren B 2013 Enhanced β cell function and anti-inflammatory effect after chronic treatment with the dipeptidyl peptidase-4 inhibitor vildagliptin in an advanced-aged diet-induced obesity mouse model. Diabetologia 56 1752-1760
-
(2013)
Diabetologia
, vol.56
, pp. 1752-1760
-
-
Omar, B.A.1
Vikman, J.2
Winzell, M.S.3
Voss, U.4
Ekblad, E.5
Foley, J.E.6
Ahren, B.7
-
63
-
-
33644850386
-
Exendin-4 uses Irs2 signaling to mediate pancreatic b cell growth and function
-
Park S, Dong X, Fisher TL, Dunn S, Omer AK, Weir G & White MF 2006 Exendin-4 uses Irs2 signaling to mediate pancreatic b cell growth and function. Journal of Biological Chemistry 281 1159-1168
-
(2006)
Journal of Biological Chemistry
, vol.281
, pp. 1159-1168
-
-
Park, S.1
Dong, X.2
Fisher, T.L.3
Dunn, S.4
Omer, A.K.5
Weir, G.6
White, M.F.7
-
64
-
-
84872700382
-
Discovery and development of exenatide: the first antidiabetic agent to leverage the multiple benefits of the incretin hormone GLP-1
-
Parkes DG, Mace KF & Trautmann ME 2013 Discovery and development of exenatide: the first antidiabetic agent to leverage the multiple benefits of the incretin hormone, GLP-1. Expert Opinion on Drug Discovery 8 219-244
-
(2013)
Expert Opinion on Drug Discovery
, vol.8
, pp. 219-244
-
-
Parkes, D.G.1
Mace, K.F.2
Trautmann, M.E.3
-
65
-
-
0034522773
-
Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats
-
Perfetti R, Zhou J, Doyle ME & Egan JM 2000 Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats. Endocrinology 141 4600-4605
-
(2000)
Endocrinology
, vol.141
, pp. 4600-4605
-
-
Perfetti, R.1
Zhou, J.2
Doyle, M.E.3
Egan, J.M.4
-
66
-
-
66649128739
-
Adaptive β-cells proliferation is severely restricted with advanced age
-
Rankin MM & Kushner JA 2009 Adaptive β-cells proliferation is severely restricted with advanced age. Diabetes 58 1365-1372
-
(2009)
Diabetes
, vol.58
, pp. 1365-1372
-
-
Rankin, M.M.1
Kushner, J.A.2
-
67
-
-
84879978428
-
New b cells are not generated by prolonged administration of incretin-based therapies (Exendin-4 or Sitagliptin) in adult mouse pancreas
-
Rankin MM, King KB, Kim JJ, Li C & Kushner JA 2012 New b cells are not generated by prolonged administration of incretin-based therapies (Exendin-4 or Sitagliptin) in adult mouse pancreas. Diabetes 61(suppl 1A) LB34
-
(2012)
Diabetes
, vol.61
, Issue.SUPPL. 1A
-
-
Rankin, M.M.1
King, K.B.2
Kim, J.J.3
Li, C.4
Kushner, J.A.5
-
68
-
-
84884903039
-
The association of pancreatitis with antidiabetic drug use: gaining insight through the FDA pharmacovigilance database
-
Raschi E, Piccinni C, Poluzzi E, Marchesini G & De Ponti F 2013 The association of pancreatitis with antidiabetic drug use: gaining insight through the FDA pharmacovigilance database. Acta Diabetologica 50 569-577
-
(2013)
Acta Diabetologica
, vol.50
, pp. 569-577
-
-
Raschi, E.1
Piccinni, C.2
Poluzzi, E.3
Marchesini, G.4
De Ponti, F.5
-
69
-
-
0036107064
-
Long- term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice
-
Reimer MK, Holst JJ & Ahren B 2002 Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice. European Journal of Endocrinology 146 717-727
-
(2002)
European Journal of Endocrinology
, vol.146
, pp. 717-727
-
-
Reimer, M.K.1
Holst, J.J.2
Ahren, B.3
-
70
-
-
0036784675
-
The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases (-cells mass in diabetic mice American Journal of Physiology
-
Rolin B, Larsen MO, Gotfredsen CF, Deacon CF, Carr RD, Wilken M & Knudsen LB 2002 The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases β-cells mass in diabetic mice American Journal of Physiology. Endocrinology and Metabolism 283 E745-E752
-
(2002)
Endocrinology and Metabolism
, vol.283
-
-
Rolin, B.1
Larsen, M.O.2
Gotfredsen, C.F.3
Deacon, C.F.4
Carr, R.D.5
Wilken, M.6
Knudsen, L.B.7
-
71
-
-
84863158593
-
Impact of the dipeptidyl peptidase-4 inhibitor vildagliptin on glucose tolerance and β-cells function and mass in insulin receptor substrate-2-knockout mice fed a high-fat diet
-
Sato K, Nakamura A, Shirakawa J,Muraoka T, Togashi Y, Shinoda K, Orime K, Kubota N, Kadowaki T & Terauchi Y 2012 Impact of the dipeptidyl peptidase-4 inhibitor vildagliptin on glucose tolerance and β-cells function and mass in insulin receptor substrate-2-knockout mice fed a high-fat diet. Endocrinology 153 1093-1102
-
(2012)
Endocrinology
, vol.153
, pp. 1093-1102
-
-
Sato, K.1
Nakamura, A.2
Shirakawa, J.3
Muraoka, T.4
Togashi, Y.5
Shinoda, K.6
Orime, K.7
Kubota, N.8
Kadowaki, T.9
Terauchi, Y.10
-
72
-
-
84866398736
-
DPP4 inhibitor vildagliptin preserves β-cells mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice
-
Shimizu S, Hosooka T, Matsuda T, Asahara S, Koyanagi-KimuraM, Kanno A, Bartolome A, Etoh H, Fuchita M, Teruyama K et al. 2012 DPP4 inhibitor vildagliptin preserves β-cells mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice Journal of Molecular Endocrinology 49 125-135
-
(2012)
Journal of Molecular Endocrinology
, vol.49
, pp. 125-135
-
-
Shimizu, S.1
Hosooka, T.2
Matsuda, T.3
Asahara, S.4
Koyanagi-Kimura, M.5
Kanno, A.6
Bartolome, A.7
Etoh, H.8
Fuchita, M.9
Teruyama, K.10
-
73
-
-
79960387066
-
Protective effects of dipeptidyl peptidase-4 (DPP-4) inhibitor against increased b cell apoptosis induced by dietary sucrose and linoleic acid in mice with diabetes
-
Shirakawa J, Amo K, Ohminami H, Orime K, Togashi Y, Ito Y, Tajima K, Koganei M, Sasaki H, Takeda E et al. 2011a Protective effects of dipeptidyl peptidase-4 (DPP-4) inhibitor against increased b cell apoptosis induced by dietary sucrose and linoleic acid in mice with diabetes. Journal of Biological Chemistry 286 25467-25476
-
(2011)
Journal of Biological Chemistry
, vol.286
, pp. 25467-25476
-
-
Shirakawa, J.1
Amo, K.2
Ohminami, H.3
Orime, K.4
Togashi, Y.5
Ito, Y.6
Tajima, K.7
Koganei, M.8
Sasaki, H.9
Takeda, E.10
-
74
-
-
79953213304
-
Diet-induced adipose tissue inflammation and liver steatosis are prevented by DPP-4 inhibition in diabetic mice
-
Shirakawa J, Fujii H,OhnumaK, Sato K, Ito Y, KajiM, Sakamoto E, Koganei M, Sasaki H, Nagashima Y et al. 2011b Diet-induced adipose tissue inflammation and liver steatosis are prevented by DPP-4 inhibition in diabetic mice. Diabetes 60 1246-1257
-
(2011)
Diabetes
, vol.60
, pp. 1246-1257
-
-
Shirakawa, J.1
Fujii, H.2
Ohnuma, K.3
Sato, K.4
Ito, Y.5
Kaji, M.6
Sakamoto, E.7
Koganei, M.8
Sasaki, H.9
Nagashima, Y.10
-
75
-
-
84876063836
-
Glucagon-like peptide, 1-based therapies and risk of hospitalization for acute pancreatitis in type 2 diabetes mellitus: a population-based matched case-control study
-
Singh S, Chang HY, Richards TM, Weiner JP, Clark JM & Segal JB 2013 Glucagon-like peptide 1-based therapies and risk of hospitalization for acute pancreatitis in type 2 diabetes mellitus: a population-based matched case-control study. JAMA Internal Medicine 173 534-539
-
(2013)
JAMA Internal Medicine
, vol.173
, pp. 534-539
-
-
Singh, S.1
Chang, H.Y.2
Richards, T.M.3
Weiner, J.P.4
Clark, J.M.5
Segal, J.B.6
-
76
-
-
84879583340
-
Adaptive β-cells proliferation increases early in high-fat feeding in mice, concurrent with metabolic changes, with induction of islet cyclin D2 expression American Journal of Physiology
-
Stamateris RE, Sharma RB, Hollern DA & Alonso LC 2013 Adaptive β-cells proliferation increases early in high-fat feeding in mice, concurrent with metabolic changes, with induction of islet cyclin D2 expression American Journal of Physiology. Endocrinology and Metabolism 305 E149-E159
-
(2013)
Endocrinology and Metabolism
, vol.305
-
-
Stamateris, R.E.1
Sharma, R.B.2
Hollern, D.A.3
Alonso, L.C.4
-
77
-
-
0034032317
-
Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas
-
Stoffers DA, Kieffer TJ, Hussain MA, Drucker DJ, Bonner-Weir S, Habener JF & Egan JM 2000 Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas. Diabetes 49 741-748
-
(2000)
Diabetes
, vol.49
, pp. 741-748
-
-
Stoffers, D.A.1
Kieffer, T.J.2
Hussain, M.A.3
Drucker, D.J.4
Bonner-Weir, S.5
Habener, J.F.6
Egan, J.M.7
-
78
-
-
0037341252
-
Neonatal exendin-4 prevents the development of diabetes in the intrauterine growth retarded rat
-
Stoffers DA, Desai BM, DeLeon DD & Simmons RA 2003 Neonatal exendin-4 prevents the development of diabetes in the intrauterine growth retarded rat. Diabetes 52 734-740
-
(2003)
Diabetes
, vol.52
, pp. 734-740
-
-
Stoffers, D.A.1
Desai, B.M.2
DeLeon, D.D.3
Simmons, R.A.4
-
79
-
-
77249086130
-
Pancreatic duct glands are distinct ductal compartments that react to chronic injury and mediate Shh-induced metaplasia
-
Strobel O, Rosow DE, Rakhlin EY, Lauwers GY, Trainor AG, Alsina J, Fernandez-Del Castillo C, Warshaw AL & Thayer SP 2010 Pancreatic duct glands are distinct ductal compartments that react to chronic injury and mediate Shh-induced metaplasia. Gastroenterology 138 1166-1177
-
(2010)
Gastroenterology
, vol.138
, pp. 1166-1177
-
-
Strobel, O.1
Rosow, D.E.2
Rakhlin, E.Y.3
Lauwers, G.Y.4
Trainor, A.G.5
Alsina, J.6
Fernandez-Del Castillo, C.7
Warshaw, A.L.8
Thayer, S.P.9
-
80
-
-
10744230106
-
GLP- 1 derivative liraglutide in rats with β-cells deficiencies: influence of metabolic state on β-cells mass dynamics
-
Sturis J, Gotfredsen CF, Romer J, Rolin B, Ribel U, Brand CL, Wilken M, Wassermann K, Deacon CF, Carr RD et al. 2003 GLP-1 derivative liraglutide in rats with β-cells deficiencies: influence of metabolic state on β-cells mass dynamics. British Journal of Pharmacology 140 123-132
-
(2003)
British Journal of Pharmacology
, vol.140
, pp. 123-132
-
-
Sturis, J.1
Gotfredsen, C.F.2
Romer, J.3
Rolin, B.4
Ribel, U.5
Brand, C.L.6
Wilken, M.7
Wassermann, K.8
Deacon, C.F.9
Carr, R.D.10
-
81
-
-
34547658090
-
Sulfonylurea and glinide reduce insulin content, functional expression of K(ATP) channels, and accelerate apoptotic β-cells death in the chronic phase
-
Takahashi A, Nagashima K, Hamasaki A, Kuwamura N, Kawasaki Y, IkedaH, Yamada Y, Inagaki N & Seino Y 2007 Sulfonylurea and glinide reduce insulin content, functional expression of K(ATP) channels, and accelerate apoptotic β-cells death in the chronic phase. Diabetes Research and Clinical Practice 77 343-350
-
(2007)
Diabetes Research and Clinical Practice
, vol.77
, pp. 343-350
-
-
Takahashi, A.1
Nagashima, K.2
Hamasaki, A.3
Kuwamura, N.4
Kawasaki, Y.5
Ikeda, H.6
Yamada, Y.7
Inagaki, N.8
Seino, Y.9
-
82
-
-
84856711643
-
Reduction of both β cell death and alpha cell proliferation by dipeptidyl peptidase-4 inhibition in a streptozotocin-induced model of diabetes in mice
-
Takeda Y, Fujita Y, Honjo J, Yanagimachi T, Sakagami H, Takiyama Y, Makino Y, Abiko A, Kieffer TJ& Haneda M 2012 Reduction of both b cell death and alpha cell proliferation by dipeptidyl peptidase-4 inhibition in a streptozotocin-induced model of diabetes in mice Diabetologia 55 404-412
-
(2012)
Diabetologia
, vol.55
, pp. 404-412
-
-
Takeda, Y.1
Fujita, Y.2
Honjo, J.3
Yanagimachi, T.4
Sakagami, H.5
Takiyama, Y.6
Makino, Y.7
Abiko, A.8
Kieffer, T.J.9
Haneda, M.10
-
83
-
-
78649658112
-
Exenatide does not evoke pancreatitis and attenuates chemically induced pancreatitis in normal and diabetic rodents
-
Tatarkiewicz K, Smith PA, Sablan EJ, Polizzi CJ, Aumann DE, Villescaz C, Hargrove DM, Gedulin BR, Lu MG, Adams L et al. 2010 Exenatide does not evoke pancreatitis and attenuates chemically induced pancreatitis in normal and diabetic rodents. American Journal of Physiology Endocrinology and Metabolism 299 E1076-E1086
-
(2010)
American Journal of Physiology Endocrinology and Metabolism
, vol.299
-
-
Tatarkiewicz, K.1
Smith, P.A.2
Sablan, E.J.3
Polizzi, C.J.4
Aumann, D.E.5
Villescaz, C.6
Hargrove, D.M.7
Gedulin, B.R.8
Lu, M.G.9
Adams, L.10
-
84
-
-
84876332227
-
Noevidence of druginduced pancreatitis in rats treated with exenatide for, 13 weeks
-
Tatarkiewicz K, Belanger P,GuG, Parkes D&Roy D 2013Noevidence of druginduced pancreatitis in rats treated with exenatide for 13 weeks. Diabetes, Obesity & Metabolism 15 417-426
-
(2013)
Diabetes, Obesity & Metabolism
, vol.15
, pp. 417-426
-
-
Tatarkiewicz, K.1
Belanger, P.2
Gu, G.3
Parkes, D.4
Roy, D.5
-
85
-
-
0035405821
-
Glucagon-like peptide-1 and exendin-4 stimulate β-cells neogenesis in streptozotocintreated newborn rats resulting in persistently improved glucose homeostasis at adult age
-
Tourrel C, Bailbe D, Meile MJ, Kergoat M & Portha B 2001 Glucagon-like peptide-1 and exendin-4 stimulate β-cells neogenesis in streptozotocintreated newborn rats resulting in persistently improved glucose homeostasis at adult age. Diabetes 50 1562-1570
-
(2001)
Diabetes
, vol.50
, pp. 1562-1570
-
-
Tourrel, C.1
Bailbe, D.2
Meile, M.J.3
Kergoat, M.4
Portha, B.5
-
86
-
-
0036312680
-
Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the β-cells mass during the prediabetic period with glucagon-like peptide-1 or exendin-4
-
Tourrel C, Bailbe D, Lacorne M, Meile MJ, Kergoat M & Portha B 2002 Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the β-cells mass during the prediabetic period with glucagon-like peptide-1 or exendin-4. Diabetes 51 1443-1452
-
(2002)
Diabetes
, vol.51
, pp. 1443-1452
-
-
Tourrel, C.1
Bailbe, D.2
Lacorne, M.3
Meile, M.J.4
Kergoat, M.5
Portha, B.6
-
87
-
-
0036687655
-
Mechanisms of mitogenic and anti-apoptotic signaling by glucose-dependent insulinotropic polypeptide in b(INS-1)-cells
-
Trumper A, Trumper K & Horsch D 2002 Mechanisms of mitogenic and anti-apoptotic signaling by glucose-dependent insulinotropic polypeptide in b(INS-1)-cells. Journal of Endocrinology 174 233-46
-
(2002)
Journal of Endocrinology
, vol.174
, pp. 233-246
-
-
Trumper, A.1
Trumper, K.2
Horsch, D.3
-
88
-
-
66649084335
-
Age- dependent decline in β-cells proliferation restricts the capacity of β-cells regeneration in mice
-
Tschen SI, Dhawan S, Gurlo T & Bhushan A 2009 Age-dependent decline in β-cells proliferation restricts the capacity of β-cells regeneration in mice Diabetes 58 1312-1320
-
(2009)
Diabetes
, vol.58
, pp. 1312-1320
-
-
Tschen, S.I.1
Dhawan, S.2
Gurlo, T.3
Bhushan, A.4
-
89
-
-
84860204551
-
Cardiovascular biology of the incretin system
-
Ussher JR & Drucker DJ 2012 Cardiovascular biology of the incretin system Endocrine Reviews 33 187-215
-
(2012)
Endocrine Reviews
, vol.33
, pp. 187-215
-
-
Ussher, J.R.1
Drucker, D.J.2
-
90
-
-
0029978228
-
Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic b cell expression of human islet amyloid polypeptide
-
Verchere CB, D'Alessio DA, Palmiter RD, WeirGC, Bonner-Weir S, BaskinDG & Kahn SE 1996 Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic b cell expression of human islet amyloid polypeptide. PNAS 93 3492-3496
-
(1996)
PNAS
, vol.93
, pp. 3492-3496
-
-
Verchere, C.B.1
D'Alessio, D.A.2
Palmiter, R.D.3
Weir, G.C.4
Bonner-Weir, S.5
Baskin, D.G.6
Kahn, S.E.7
-
91
-
-
84863950236
-
The effects of 13 wk of liraglutide treatment on endocrine and exocrine pancreas in male and female ZDF rats: a quantitative and qualitative analysis revealing no evidence of drug-induced pancreatitis. American Journal of Physiology
-
Vrang N, Jelsing J, Simonsen L, Jensen AE, Thorup I, SoeborgH&Knudsen LB 2012 The effects of 13 wk of liraglutide treatment on endocrine and exocrine pancreas in male and female ZDF rats: a quantitative and qualitative analysis revealing no evidence of drug-induced pancreatitis. American Journal of Physiology. Endocrinology and Metabolism 303 E253-E264
-
(2012)
Endocrinology and Metabolism
, vol.303
-
-
Vrang, N.1
Jelsing, J.2
Simonsen, L.3
Jensen, A.E.4
Thorup, I.5
Soeborg, H.6
Knudsen, L.B.7
-
92
-
-
0036381989
-
Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice
-
Wang Q & Brubaker PL 2002 Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice. Diabetologia 45 1263-1273
-
(2002)
Diabetologia
, vol.45
, pp. 1263-1273
-
-
Wang, Q.1
Brubaker, P.L.2
-
93
-
-
0033305746
-
Glucagon-like peptide-1 regulates the b cell transcription factor, PDX-1, in insulinoma cells
-
Wang X, Cahill CM, Pineyro MA, Zhou J, Doyle ME & Egan JM 1999 Glucagon-like peptide-1 regulates the b cell transcription factor, PDX-1, in insulinoma cells. Endocrinology 140 4904-4907
-
(1999)
Endocrinology
, vol.140
, pp. 4904-4907
-
-
Wang, X.1
Cahill, C.M.2
Pineyro, M.A.3
Zhou, J.4
Doyle, M.E.5
Egan, J.M.6
-
94
-
-
1842855402
-
Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 b cells
-
Wang Q, Li L, Xu E, Wong V, Rhodes C & Brubaker PL 2004 Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 b cells. Diabetologia 47 478-487
-
(2004)
Diabetologia
, vol.47
, pp. 478-487
-
-
Wang, Q.1
Li, L.2
Xu, E.3
Wong, V.4
Rhodes, C.5
Brubaker, P.L.6
-
95
-
-
0033513455
-
Exendin-4 stimulates both β-cells replication and neogenesis, resulting in increased β-cells mass and improved glucose tolerance in diabetic rats
-
Xu G, Stoffers DA, Habener JF & Bonner-Weir S 1999 Exendin-4 stimulates both β-cells replication and neogenesis, resulting in increased β-cells mass and improved glucose tolerance in diabetic rats. Diabetes 48 2270-2276
-
(1999)
Diabetes
, vol.48
, pp. 2270-2276
-
-
Xu, G.1
Stoffers, D.A.2
Habener, J.F.3
Bonner-Weir, S.4
-
96
-
-
84863230187
-
Both sitagliptin analogue & pioglitazone preserve the β-cells proportion in the islets with different mechanism in non-obese and obese diabetic mice
-
Yeom JA, Kim ES, Park HS, Ham DS, Sun C, Kim JW, Cho JH & Yoon KH 2011 Both sitagliptin analogue & pioglitazone preserve the β-cells proportion in the islets with different mechanism in non-obese and obese diabetic mice. BMB Reports 44 713-718
-
(2011)
BMB Reports
, vol.44
, pp. 713-718
-
-
Yeom, J.A.1
Kim, E.S.2
Park, H.S.3
Ham, D.S.4
Sun, C.5
Kim, J.W.6
Cho, J.H.7
Yoon, K.H.8
-
97
-
-
79951867513
-
Effects of chronic administration of alogliptin on the development of diabetes and β-cells function in high fat diet/streptozotocin diabetic mice
-
Zhang X, Wang Z, Huang Y & Wang J 2011 Effects of chronic administration of alogliptin on the development of diabetes and β-cells function in high fat diet/streptozotocin diabetic mice. Diabetes, Obesity & Metabolism 13 337-347
-
(2011)
Diabetes, Obesity & Metabolism
, vol.13
, pp. 337-347
-
-
Zhang, X.1
Wang, Z.2
Huang, Y.3
Wang, J.4
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