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Volumn 53, Issue 1, 2010, Pages 153-159

Biochemical and histological effects of exendin-4 (exenatide) on the rat pancreas

Author keywords

Amylase; Exenatide; Exendin 4; Lipase; Pancreatitis

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; ALANINE AMINOTRANSFERASE; AMYLASE; ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; EXENDIN 4; GLUCOSE; INSULIN; LEPTIN; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE;

EID: 72449157026     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-009-1515-4     Document Type: Article
Times cited : (163)

References (22)
  • 1
    • 33646354927 scopus 로고    scopus 로고
    • Exenatide (exendin-4)-induced pancreatitis: A case report
    • 10.2337/diacare.29.02.06.dc05-2043 16443920
    • PS Denker PE Dimarco 2006 Exenatide (exendin-4)-induced pancreatitis: a case report Diabetes Care 29 471 10.2337/diacare.29.02.06.dc05-2043 16443920
    • (2006) Diabetes Care , vol.29 , pp. 471
    • Denker, P.S.1    Dimarco, P.E.2
  • 2
    • 0036965113 scopus 로고    scopus 로고
    • The insulinotropic effect of acute exendin-4 administered to humans: Comparison of nondiabetic state to type 2 diabetes
    • DOI 10.1210/jc.87.3.1282
    • JM Egan AR Clocquet D Elahi 2002 The insulinotropic effect of acute exendin-4 administered to humans: comparison of nondiabetic state to type 2 diabetes J Clin Endocrinol Metab 87 1282 1290 10.1210/jc.87.3.1282 1:CAS:528:DC%2BD38XitlWns7k%3D 11889200 (Pubitemid 36121100)
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , Issue.3 , pp. 1282-1290
    • Egan, J.M.1    Clocquet, A.R.2    Elahi, D.3
  • 3
    • 33644840976 scopus 로고    scopus 로고
    • Role of glucagon-like peptide-1 in the pathogenesis and treatment of diabetes mellitus
    • DOI 10.1016/j.biocel.2005.07.011, PII S1357272505002566, Diabetes: New Research and Novel Therapies
    • DD De Leon MF Crutchlow JY Ham DA Stoffers 2006 Role of glucagon-like peptide-1 in the pathogenesis and treatment of diabetes mellitus Int J Biochem Cell Biol 38 845 859 10.1016/j.biocel.2005.07.011 16202636 (Pubitemid 43363416)
    • (2006) International Journal of Biochemistry and Cell Biology , vol.38 , Issue.5-6 , pp. 845-859
    • Leon, D.D.D.1    Crutchlow, M.F.2    Ham, J.-Y.N.3    Stoffers, D.A.4
  • 4
    • 0027184119 scopus 로고
    • Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells
    • 1:STN:280:DyaK3sznsV2lsw%3D%3D 8396143
    • R Goke HC Fehmann T Linn, et al. 1993 Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells J Biol Chem 268 19650 19655 1:STN:280:DyaK3sznsV2lsw%3D%3D 8396143
    • (1993) J Biol Chem , vol.268 , pp. 19650-19655
    • Goke, R.1    Fehmann, H.C.2    Linn, T.3
  • 5
    • 42949089442 scopus 로고    scopus 로고
    • Exenatide and rare adverse events
    • 1:CAS:528:DC%2BD1cXlt1KjtrY%3D 18456920 discussion 1971-1972
    • SR Ahmad J Swann 2008 Exenatide and rare adverse events N Engl J Med 358 1970 1971 1:CAS:528:DC%2BD1cXlt1KjtrY%3D 18456920 discussion 1971-1972
    • (2008) N Engl J Med , vol.358 , pp. 1970-1971
    • Ahmad, S.R.1    Swann, J.2
  • 6
    • 72449188040 scopus 로고    scopus 로고
    • FDA U.S. Food and Drug Administration (exanatide) October 2007. Available from accessed 21 November 2008
    • FDA U.S. Food and Drug Administration (2007) Byetta (exanatide) October 2007. Available from www.fda.gov/Safety/MedWatch/SafetyInformation/ SafetyAlertsforHumanMedicalProducts/ucm150839.htm, accessed 21 November 2008
    • (2007) Byetta
  • 7
    • 33644803761 scopus 로고    scopus 로고
    • Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice
    • DOI 10.1002/hep.21006
    • X Ding NK Saxena S Lin NA Gupta FA Anania 2006 Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice Hepatology 43 173 181 10.1002/hep.21006 1:CAS:528:DC%2BD28Xpt1Snsw%3D%3D 16374859 (Pubitemid 43733604)
    • (2006) Hepatology , vol.43 , Issue.1 , pp. 173-181
    • Ding, X.1    Saxena, N.K.2    Lin, S.3    Gupta, N.4    Anania, F.A.5
  • 8
    • 0029591623 scopus 로고
    • Inhibitors of angiotensin-converting enzyme modulate mitosis and gene expression in pancreatic cancer cells
    • 1:CAS:528:DyaK28XivFalug%3D%3D 8539259
    • MK Reddy K Baskaran A Molteni 1995 Inhibitors of angiotensin-converting enzyme modulate mitosis and gene expression in pancreatic cancer cells Proc Soc Exp Biol Med 210 221 226 1:CAS:528:DyaK28XivFalug%3D%3D 8539259
    • (1995) Proc Soc Exp Biol Med , vol.210 , pp. 221-226
    • Reddy, M.K.1    Baskaran, K.2    Molteni, A.3
  • 9
    • 0018747714 scopus 로고
    • Estradiol receptor assays in normal and neoplastic tissues. A possible diagnostic acid for tumor differentiation
    • 1:CAS:528:DyaE1MXhvVCms7Y%3D 453784
    • A Molteni RM Bahu HA Battifora, et al. 1979 Estradiol receptor assays in normal and neoplastic tissues. A possible diagnostic acid for tumor differentiation Ann Clin Lab Sci 9 103 108 1:CAS:528:DyaE1MXhvVCms7Y%3D 453784
    • (1979) Ann Clin Lab Sci , vol.9 , pp. 103-108
    • Molteni, A.1    Bahu, R.M.2    Battifora, H.A.3
  • 10
    • 0035758111 scopus 로고    scopus 로고
    • Prevention of radiation-induced nephropathy and fibrosis in a model of bone marrow transplant by an angiotensin II receptor blocker
    • 1:CAS:528:DC%2BD3MXptlOjs78%3D
    • A Molteni JE Moulder EP Cohen, et al. 2001 Prevention of radiation-induced nephropathy and fibrosis in a model of bone marrow transplant by an angiotensin II receptor blocker Exp Biol Med (Maywood) 226 1016 1023 1:CAS:528:DC%2BD3MXptlOjs78%3D
    • (2001) Exp Biol Med (Maywood) , vol.226 , pp. 1016-1023
    • Molteni, A.1    Moulder, J.E.2    Cohen, E.P.3
  • 11
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
    • DOI 10.1007/BF00280883
    • DR Matthews JP Hosker AS Rudenski BA Naylor DF Treacher RC Turner 1985 Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man Diabetologia 28 412 419 10.1007/BF00280883 1:CAS:528:DyaL2MXlslKnu7k%3D 3899825 (Pubitemid 15018832)
    • (1985) Diabetologia , vol.28 , Issue.7 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3
  • 12
    • 33645533439 scopus 로고    scopus 로고
    • Exenatide: From the Gila monster to the pharmacy
    • 10.1331/154434506775268698 quiz 53-54
    • C Triplitt E Chiquette 2006 Exenatide: from the Gila monster to the pharmacy J Am Pharm Assoc (2003) 46 44 52 10.1331/154434506775268698 quiz 53-54
    • (2006) J Am Pharm Assoc , vol.46 , pp. 44-52
    • Triplitt, C.1    Chiquette, E.2
  • 13
    • 34249066125 scopus 로고    scopus 로고
    • Acute pancreatitis: Diagnosis, prognosis, and treatment
    • 17555143
    • JK Carroll B Herrick T Gipson SP Lee 2007 Acute pancreatitis: diagnosis, prognosis, and treatment Am Fam Physician 75 1513 1520 17555143
    • (2007) Am Fam Physician , vol.75 , pp. 1513-1520
    • Carroll, J.K.1    Herrick, B.2    Gipson, T.3    Lee, S.P.4
  • 14
    • 0036022407 scopus 로고    scopus 로고
    • Initiator caspases in apoptosis signaling pathways
    • DOI 10.1023/A:1016167228059
    • M Chen J Wang 2002 Initiator caspases in apoptosis signaling pathways Apoptosis 7 313 319 10.1023/A:1016167228059 1:CAS:528:DC%2BD38XltVSgtbw%3D 12101390 (Pubitemid 34832255)
    • (2002) Apoptosis , vol.7 , Issue.4 , pp. 313-319
    • Chen, M.1    Wang, J.2
  • 16
    • 70349120958 scopus 로고    scopus 로고
    • GLP-1 receptor activation modulates pancreatitis-associated gene expression but does not modify the susceptibility to experimental pancreatitis in mice
    • 10.2337/db09-0626
    • JA Koehler LL Baggio BJ Lamont S Ali DJ Drucker 2009 GLP-1 receptor activation modulates pancreatitis-associated gene expression but does not modify the susceptibility to experimental pancreatitis in mice Diabetes 58 1604 1615 10.2337/db09-0626
    • (2009) Diabetes , vol.58 , pp. 1604-1615
    • Koehler, J.A.1    Baggio, L.L.2    Lamont, B.J.3    Ali, S.4    Drucker, D.J.5
  • 17
    • 67650245531 scopus 로고    scopus 로고
    • Beneficial endocrine but adverse exocrine effects of sitagliptin in the HIP rat model of type 2 diabetes, interactions with metformin
    • 10.2337/db09-0058 1:CAS:528:DC%2BD1MXos1Cqu74%3D 19403868
    • AV Matveyenko S Dry HI Cox, et al. 2009 Beneficial endocrine but adverse exocrine effects of sitagliptin in the HIP rat model of type 2 diabetes, interactions with metformin Diabetes 58 1604 1615 10.2337/db09-0058 1:CAS:528:DC%2BD1MXos1Cqu74%3D 19403868
    • (2009) Diabetes , vol.58 , pp. 1604-1615
    • Matveyenko, A.V.1    Dry, S.2    Cox, H.I.3
  • 18
    • 0034032317 scopus 로고    scopus 로고
    • Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas
    • 10.2337/diabetes.49.5.741 1:CAS:528:DC%2BD3cXjsF2msrc%3D 10905482
    • DA Stoffers TJ Kieffer MA Hussain, et al. 2000 Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas Diabetes 49 741 748 10.2337/diabetes.49.5.741 1:CAS:528:DC%2BD3cXjsF2msrc%3D 10905482
    • (2000) Diabetes , vol.49 , pp. 741-748
    • Stoffers, D.A.1    Kieffer, T.J.2    Hussain, M.A.3
  • 19
    • 0026824479 scopus 로고
    • Exendin peptides
    • 1:STN:280:DyaK383ksValug%3D%3D 1574068
    • J Eng 1992 Exendin peptides Mt Sinai J Med 59 147 149 1:STN:280:DyaK383ksValug%3D%3D 1574068
    • (1992) Mt Sinai J Med , vol.59 , pp. 147-149
    • Eng, J.1
  • 20
    • 0026666235 scopus 로고
    • Exendin-4, a new peptide from Heloderma suspectum venom, potentiates cholecystokinin-induced amylase release from rat pancreatic acini
    • 10.1016/0167-0115(92)90044-U 1:CAS:528:DyaK38Xmt1yisLo%3D 1279756
    • R Malhotra L Singh J Eng JP Raufman 1992 Exendin-4, a new peptide from Heloderma suspectum venom, potentiates cholecystokinin-induced amylase release from rat pancreatic acini Regul Pept 41 149 156 10.1016/0167-0115(92)90044-U 1:CAS:528:DyaK38Xmt1yisLo%3D 1279756
    • (1992) Regul Pept , vol.41 , pp. 149-156
    • Malhotra, R.1    Singh, L.2    Eng, J.3    Raufman, J.P.4
  • 21
    • 52649162401 scopus 로고    scopus 로고
    • Adiponectin plays a protective role in caerulein-induced acute pancreatitis in mice fed a high-fat diet
    • 10.1136/gut.2007.135665 1:CAS:528:DC%2BD1cXht1KksLjJ 18579666
    • H Araki T Nishihara M Matsuda, et al. 2008 Adiponectin plays a protective role in caerulein-induced acute pancreatitis in mice fed a high-fat diet Gut 57 1431 1440 10.1136/gut.2007.135665 1:CAS:528:DC%2BD1cXht1KksLjJ 18579666
    • (2008) Gut , vol.57 , pp. 1431-1440
    • Araki, H.1    Nishihara, T.2    Matsuda, M.3
  • 22
    • 57049106441 scopus 로고    scopus 로고
    • Exenatide and pancreatitis: An update
    • 10.1517/14740330802432003 18983211
    • SC Bain JW Stephens 2008 Exenatide and pancreatitis: an update Expert Opin Drug Saf 7 643 644 10.1517/14740330802432003 18983211
    • (2008) Expert Opin Drug Saf , vol.7 , pp. 643-644
    • Bain, S.C.1    Stephens, J.W.2


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