-
1
-
-
0036189831
-
The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men
-
AGERSØ, H., JENSEN, L.B., ELBRØND, B., ROLAN, P. & ZDRAVKOVIC, M. (2002). The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men. Diabetologia, 45, 195-202.
-
(2002)
Diabetologia
, vol.45
, pp. 195-202
-
-
AgersØ, H.1
Jensen, L.B.2
ElbrØnd, B.3
Rolan, P.4
Zdravkovic, M.5
-
2
-
-
0032863817
-
Unbiased estimation of total beta-cell number and mean beta-cell volume in rodent pancreas
-
BOCK, T., SVENSTRUP, K., PAKKENBERG, B. & BUSCHARD, K. (1999). Unbiased estimation of total beta-cell number and mean beta-cell volume in rodent pancreas. APMIS, 107, 791-799.
-
(1999)
APMIS
, vol.107
, pp. 791-799
-
-
Bock, T.1
Svenstrup, K.2
Pakkenberg, B.3
Buschard, K.4
-
3
-
-
0002604912
-
The GLP-1 derivative NN2211 inhibits cytokine-induced apoptosis in primary rat β-cells
-
BREGENHOLT, S., MOLDRUP, A., KNUDSEN, L.B. & PETERSEN, J.S. (2001). The GLP-1 derivative NN2211 inhibits cytokine-induced apoptosis in primary rat β-cells. Diabetes, 50 (Suppl 2), A31.
-
(2001)
Diabetes
, vol.50
, Issue.2 SUPPL.
-
-
Bregenholt, S.1
Moldrup, A.2
Knudsen, L.B.3
Petersen, J.S.4
-
4
-
-
0035434115
-
Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor
-
BURCELIN, R., DA COSTA, A., DRUCKER, D. & THORENS, B. (2001). Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor. Diabetes, 50, 1720-1728.
-
(2001)
Diabetes
, vol.50
, pp. 1720-1728
-
-
Burcelin, R.1
Da Costa, A.2
Drucker, D.3
Thorens, B.4
-
5
-
-
0032768616
-
Glp-1 promotes DNA synthesis, activates phosphatidylinositol-3-kinase and increases transcription factor pancreatic and duodenal home-box gene 1 (PDX-1) DNA binding activity in beta (INS-1) cells
-
BUTEAU, J., RODUIT, R., SUSINI, S. & PRENTKI, M. (1999). Glp-1 promotes DNA synthesis, activates phosphatidylinositol-3-kinase and increases transcription factor pancreatic and duodenal home-box gene 1 (PDX-1) DNA binding activity in beta (INS-1) cells. Diabetologia, 42, 856-864.
-
(1999)
Diabetologia
, vol.42
, pp. 856-864
-
-
Buteau, J.1
Roduit, R.2
Susini, S.3
Prentki, M.4
-
6
-
-
0020534907
-
The diabetic Zucker Fatty rat
-
CLARK, J.B., PALMER, C.J. & SHAW, W.N. (1983). The diabetic Zucker Fatty rat. Proc. Soc. Exp. Biol. Med., 173, 68-75.
-
(1983)
Proc. Soc. Exp. Biol. Med.
, vol.173
, pp. 68-75
-
-
Clark, J.B.1
Palmer, C.J.2
Shaw, W.N.3
-
7
-
-
0024355498
-
Effects of glucacon-like peptide I-(7-36) on release of insulin, glucagon, and somatostatin by rat pancreatic islet cell monolayer cultures
-
D'ALESSIO, D.A., FUJIMOTO, W.Y. & ENSINCK, J.W. (1989). Effects of glucacon-like peptide I-(7-36) on release of insulin, glucagon, and somatostatin by rat pancreatic islet cell monolayer cultures. Diabetes, 38, 1534-1538.
-
(1989)
Diabetes
, vol.38
, pp. 1534-1538
-
-
D'Alessio, D.A.1
Fujimoto, W.Y.2
Ensinck, J.W.3
-
8
-
-
0028953577
-
Degradation of glucagons-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide which is a major endogenous metabolite in vivo
-
DEACON, C.F., JOHNSEN, A.H. & HOLST, J.J. (1995). Degradation of glucagons-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide which is a major endogenous metabolite in vivo. J. Clin. Endocrinol. Metab., 80, 952-957.
-
(1995)
J. Clin. Endocrinol. Metab.
, vol.80
, pp. 952-957
-
-
Deacon, C.F.1
Johnsen, A.H.2
Holst, J.J.3
-
9
-
-
0029797540
-
Glucagon-like peptide 1 undergoes differential tissue-specific metabolism in anesthetized pig
-
DEACON, C.F., PRIMDAL, L., KLARSKOV, L., OLESEN, M. & HOLST, J.J. (1996). Glucagon-like peptide 1 undergoes differential tissue-specific metabolism in anesthetized pig. Am. J. Physiol., 271, E458-E464.
-
(1996)
Am. J. Physiol.
, vol.271
-
-
Deacon, C.F.1
Primdal, L.2
Klarskov, L.3
Olesen, M.4
Holst, J.J.5
-
10
-
-
0032908809
-
Initiation of increased pancreatic islet growth in young normoglycaemic mice (Umeå +/?)
-
EDVELL, A. & LINDSTRÖM, P. (1999). Initiation of increased pancreatic islet growth in young normoglycaemic mice (Umeå +/?). Endocrinology, 140, 778-783.
-
(1999)
Endocrinology
, vol.140
, pp. 778-783
-
-
Edvell, A.1
Lindström, P.2
-
11
-
-
0034031083
-
Profiling of Zucker diabetic fatty rats in their progression to the overt diabetic state
-
ETGEN, G.J. & OLDHAM, B.A. (2000). Profiling of Zucker diabetic fatty rats in their progression to the overt diabetic state. Metabolism, 49, 684-688.
-
(2000)
Metabolism
, vol.49
, pp. 684-688
-
-
Etgen, G.J.1
Oldham, B.A.2
-
12
-
-
0036828227
-
Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats
-
FARILLA, L., HUI, H., BERTOLOTTO, C., KANG, E., BULOTTA, A., DI MARIO, U. & PERFETTI, R. (2002). Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats. Endocrinology, 143, 4397-4408.
-
(2002)
Endocrinology
, vol.143
, pp. 4397-4408
-
-
Farilla, L.1
Hui, H.2
Bertolotto, C.3
Kang, E.4
Bulotta, A.5
Di Mario, U.6
Perfetti, R.7
-
13
-
-
0032005005
-
GLP-1 promotes satiety and suppresses energy intake in humans
-
FLINT, A., RABEN, A., ASTRUP, A. & HOLST, J.J. (1998). GLP-1 promotes satiety and suppresses energy intake in humans. J. Clin. Invest., 101, 515-520.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 515-520
-
-
Flint, A.1
Raben, A.2
Astrup, A.3
Holst, J.J.4
-
14
-
-
0026340531
-
Altered expression of muscle glucose transporter GLUT-4 in diabetic fatty Zucker rats (ZDF/Drt-fa)
-
FRIEDMAN, J.E., DE VENTE, J.E., PETERSON, R.G. & DOHM, G.L. (1991). Altered expression of muscle glucose transporter GLUT-4 in diabetic fatty Zucker rats (ZDF/Drt-fa). Am. J. Physiol., 261, E782-E788.
-
(1991)
Am. J. Physiol.
, vol.261
-
-
Friedman, J.E.1
De Vente, J.E.2
Peterson, R.G.3
Dohm, G.L.4
-
15
-
-
0032932825
-
Once daily injection of exendin-4 to diabetic mice achieves long-term beneficial effects on blood glucose concentrations
-
GREIG, N.H., HOLLOWAY, H.N., DEORE, K.A., JANI, D., WANG, Y., ZHOU, J., GARANT, M.J. & EGAN, J.M. (1999). Once daily injection of exendin-4 to diabetic mice achieves long-term beneficial effects on blood glucose concentrations. Diabetologia, 42, 45-50.
-
(1999)
Diabetologia
, vol.42
, pp. 45-50
-
-
Greig, N.H.1
Holloway, H.N.2
Deore, K.A.3
Jani, D.4
Wang, Y.5
Zhou, J.6
Garant, M.J.7
Egan, J.M.8
-
16
-
-
0035149733
-
A genetic defect in β-cell gene expression segregates independently from the fa locus in the ZDF rat
-
GRIFFEN, S.C., WANG, J. & GERMAN, M.S. (2001). A genetic defect in β-cell gene expression segregates independently from the fa locus in the ZDF rat. Diabetes, 50, 63-68.
-
(2001)
Diabetes
, vol.50
, pp. 63-68
-
-
Griffen, S.C.1
Wang, J.2
German, M.S.3
-
17
-
-
0031910187
-
Cellular regulation of islet hormone secretion by the incretin hormone GLP-1
-
GROMADA, J., HOLST, J.J. & RORSMAN, P. (1998). Cellular regulation of islet hormone secretion by the incretin hormone GLP-1. Pflugers Arch. Eur. J. Phys., 435, 583-594.
-
(1998)
Pflugers Arch. Eur. J. Phys.
, vol.435
, pp. 583-594
-
-
Gromada, J.1
Holst, J.J.2
Rorsman, P.3
-
18
-
-
0028071448
-
Subcutaneous injection of the incretin hormone GLP-1 abolishes postprandial glycemia in NIDDM
-
GUTNIAK, M.K., LINDE, B., HOLST, J.J. & EFENDIC, S. (1994). Subcutaneous injection of the incretin hormone GLP-1 abolishes postprandial glycemia in NIDDM. Diabetes Care, 17, 1039-1044.
-
(1994)
Diabetes Care
, vol.17
, pp. 1039-1044
-
-
Gutniak, M.K.1
Linde, B.2
Holst, J.J.3
Efendic, S.4
-
19
-
-
0030901415
-
Enteroglucagon
-
HOLST, J.J. (1997). Enteroglucagon. Annu. Rev. Physiol., 59, 257-271.
-
(1997)
Annu. Rev. Physiol.
, vol.59
, pp. 257-271
-
-
Holst, J.J.1
-
20
-
-
0032794126
-
The role of growth hormone and glucocorticoid in glucose handling in vivo
-
JOHANSEN, I., DECKERT, M., MANDRUP-POULSEN, T. & MALMLÖF, K. (1999). The role of growth hormone and glucocorticoid in glucose handling in vivo. J. Endocrinol., 162, 87-93.
-
(1999)
J. Endocrinol.
, vol.162
, pp. 87-93
-
-
Johansen, I.1
Deckert, M.2
Mandrup-Poulsen, T.3
Malmlöf, K.4
-
21
-
-
0036066641
-
Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reduces fasting and postprandial glycemia in Type 2 diabetes
-
JUHL, C.B., HOLLINGDAL, M., PORKSEN, N., STURIS, J., JAKOBSEN, G. & SCHMITZ, O. (2002). Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reduces fasting and postprandial glycemia in Type 2 diabetes. Diabetes, 51, 484-492.
-
(2002)
Diabetes
, vol.51
, pp. 484-492
-
-
Juhl, C.B.1
Hollingdal, M.2
Porksen, N.3
Sturis, J.4
Jakobsen, G.5
Schmitz, O.6
-
22
-
-
0034108646
-
Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration
-
KNUDSEN, L.B., NIELSEN, P.F., HUUSFELDT, P.O., JOHANSEN, N.L., MADSEN, K., PEDERSEN, F.Z., THØGERSEN, H., WILKEN, M. & AGERSØ, H. (2000). Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration. J. Med. Chem., 43, 1664-1669.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 1664-1669
-
-
Knudsen, L.B.1
Nielsen, P.F.2
Huusfeldt, P.O.3
Johansen, N.L.4
Madsen, K.5
Pedersen, F.Z.6
ThØgersen, H.7
Wilken, M.8
AgersØ, H.9
-
23
-
-
0023638829
-
Glucagon-like peptide-1 7-36: A physiological incretin in man
-
KREYMANN, B., GHATEI, M.A., WILLIAMS, G. & BLOOM, S.R. (1987). Glucagon-like peptide-1 7-36: a physiological incretin in man. Lancet, II, 1300-1303.
-
(1987)
Lancet
, vol.2
, pp. 1300-1303
-
-
Kreymann, B.1
Ghatei, M.A.2
Williams, G.3
Bloom, S.R.4
-
24
-
-
0035432607
-
Glucagon-like peptide-1 infusion must be maintained for 24h/day to obtain acceptable glycemia in type 2 diabetic patients who are poorly controlled on sulphonylurea treatment
-
LARSEN, J., HYLLEBERG, G., NG, K. & DAMSBO, P. (2001a). Glucagon-like peptide-1 infusion must be maintained for 24h/day to obtain acceptable glycemia in type 2 diabetic patients who are poorly controlled on sulphonylurea treatment. Diabetes Care, 24, 1416-1421.
-
(2001)
Diabetes Care
, vol.24
, pp. 1416-1421
-
-
Larsen, J.1
Hylleberg, G.2
Ng, K.3
Damsbo, P.4
-
25
-
-
0035516188
-
Systemic administration of the long-acting GLP-1 derivative NN2211 induces lasting and reversible weight loss in both normal and obese rats
-
LARSEN, P.J., FLEDELIUS, C., KNUDSEN, L.B. & TANG-CHRISTENSEN, M. (2001b). Systemic administration of the long-acting GLP-1 derivative NN2211 induces lasting and reversible weight loss in both normal and obese rats. Diabetes, 50, 2530-2539.
-
(2001)
Diabetes
, vol.50
, pp. 2530-2539
-
-
Larsen, P.J.1
Fledelius, C.2
Knudsen, L.B.3
Tang-Christensen, M.4
-
26
-
-
0037414781
-
Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis
-
LI, Y., HANSOTIA, T., YUSTA, B., RIS, F., HALBAN, P.A. & DRUCKER, D.J. (2003). Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis. J. Biol. Chem., 278, 471-478.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 471-478
-
-
Li, Y.1
Hansotia, T.2
Yusta, B.3
Ris, F.4
Halban, P.A.5
Drucker, D.J.6
-
27
-
-
0033859232
-
Beta-cell adaptation in 60% pancreatectomy rats that preserves normoinsulinemia and normoglycemia
-
LIU, Y.Q., NEVIN, P.W. & LEAHY, J.L. (2000). Beta-cell adaptation in 60% pancreatectomy rats that preserves normoinsulinemia and normoglycemia. Am. J. Physiol., 278, E68-E73.
-
(2000)
Am. J. Physiol.
, vol.278
-
-
Liu, Y.Q.1
Nevin, P.W.2
Leahy, J.L.3
-
28
-
-
0036894315
-
The multiple actions of GLP-1 on the process of glucose-stimulated insulin secretion
-
MACDONALD, P.E., EL-KHOLY, W., RIEDEL, M.J., SALAPATEK, A.M.F., LIGHT, P.E. & WHEELER, M.B. (2002). The multiple actions of GLP-1 on the process of glucose-stimulated insulin secretion. Diabetes, 51 (Suppl 3), S434-S442.
-
(2002)
Diabetes
, vol.51
, Issue.3 SUPPL.
-
-
Macdonald, P.E.1
El-Kholy, W.2
Riedel, M.J.3
Salapatek, A.M.F.4
Light, P.E.5
Wheeler, M.B.6
-
29
-
-
0027215348
-
Dipeptidyl peptidase IV hydrolyses gastric inhibitory polypeptide, glucagons-like peptide-1 (7-36) amide, peptide histidine methionine and is responsible for their degradation in human serum
-
MENTLEIN, R., GALLWITZ, B. & SCHMIDT, W.E. (1993). Dipeptidyl peptidase IV hydrolyses gastric inhibitory polypeptide, glucagons-like peptide-1 (7-36) amide, peptide histidine methionine and is responsible for their degradation in human serum. Eur. J. Biochem., 214, 829-835.
-
(1993)
Eur. J. Biochem.
, vol.214
, pp. 829-835
-
-
Mentlein, R.1
Gallwitz, B.2
Schmidt, W.E.3
-
30
-
-
0037513100
-
Glucagon-like peptide-1 (GLP-1) and the long-acting GLP-1 derivative, NN2211, stimulate expansion of primary rat beta-cells in a camp/protein kinase A (PKA)-dependent manner
-
MOLDRUP, A., GRAM, V.K., FRIEDRICHSEN, B.N., NIELSEN, J.H. & PETERSEN, J.S. (2001). Glucagon-like peptide-1 (GLP-1) and the long-acting GLP-1 derivative, NN2211, stimulate expansion of primary rat beta-cells in a camp/protein kinase A (PKA)-dependent manner. Diabetes, 50 (Suppl 2), A336.
-
(2001)
Diabetes
, vol.50
, Issue.2 SUPPL.
-
-
Moldrup, A.1
Gram, V.K.2
Friedrichsen, B.N.3
Nielsen, J.H.4
Petersen, J.S.5
-
31
-
-
0036775170
-
Exendin 4 up-regulates expression of PDX 1 and hastens differentiation and maturation of human fetal pancreatic cells
-
MOVASSAT, J., BEATTIE, G.M., LOPEZ, A.D. & HAYEK, A. (2002). Exendin 4 up-regulates expression of PDX 1 and hastens differentiation and maturation of human fetal pancreatic cells. J. Clin. Endocrinol. Metab., 87, 4775-4781.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 4775-4781
-
-
Movassat, J.1
Beattie, G.M.2
Lopez, A.D.3
Hayek, A.4
-
32
-
-
0027248866
-
Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients
-
NAUCK, M.A., KLEINE, N., ORSKOV, C., HOLST, J.J., WILLMS, B. & CREUTZFELDT, W. (1993). Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients. Diabetologia, 36, 741-744.
-
(1993)
Diabetologia
, vol.36
, pp. 741-744
-
-
Nauck, M.A.1
Kleine, N.2
Orskov, C.3
Holst, J.J.4
Willms, B.5
Creutzfeldt, W.6
-
33
-
-
0030667056
-
Glucagon-like peptide-1 inhibition of gastric-emptying outweighs its insulinotropic effects in healthy humans
-
NAUCK, M.A., NIEDEREREICHHOLZ, U., ETTLER, R., HOLST, J.J., ØRSKOV, C., RITZEL, R. & SCHMIGEL, W.H. (1997). Glucagon-like peptide-1 inhibition of gastric-emptying outweighs its insulinotropic effects in healthy humans. Am. J. Physiol., 273, E981-E988.
-
(1997)
Am. J. Physiol.
, vol.273
-
-
Nauck, M.A.1
Niederereichholz, U.2
Ettler, R.3
Holst, J.J.4
Ørskov, C.5
Ritzel, R.6
Schmigel, W.H.7
-
34
-
-
0028833276
-
Caloric restriction in obese pre-diabetic rats prevents beta-cell depletion, loss of beta-cell GLUT 2 and glucose incompetence
-
OHNEDA, M., INMAN, L.R. & UNGER, R.H. (1995). Caloric restriction in obese pre-diabetic rats prevents beta-cell depletion, loss of beta-cell GLUT 2 and glucose incompetence. Diabetologia, 38, 173-179.
-
(1995)
Diabetologia
, vol.38
, pp. 173-179
-
-
Ohneda, M.1
Inman, L.R.2
Unger, R.H.3
-
35
-
-
0026659679
-
Glucagon-like peptide-1, a new hormone of the enteroinsular axis
-
ØRSKOV, C. (1992). Glucagon-like peptide-1, a new hormone of the enteroinsular axis. Diabetologia, 35, 701-711.
-
(1992)
Diabetologia
, vol.35
, pp. 701-711
-
-
Ørskov, C.1
-
36
-
-
0034522773
-
Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats
-
PERFETTI, R., ZHOU, J., DOYLE, M.E. & EGAN, J.M. (2000). Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats. Endocrinology, 141, 4600-4605.
-
(2000)
Endocrinology
, vol.141
, pp. 4600-4605
-
-
Perfetti, R.1
Zhou, J.2
Doyle, M.E.3
Egan, J.M.4
-
37
-
-
0030137757
-
Leptin receptor missense mutation in the fatty Zucker rat
-
PHILLIPS, M.S., LIU, Q., HAMMOND, H.A., DUGAN, V., HEY, P.J., CASKEY, C.J. & HESS, J.F. (1996). Leptin receptor missense mutation in the fatty Zucker rat. Nat. Genet., 13, 18-19.
-
(1996)
Nat. Genet.
, vol.13
, pp. 18-19
-
-
Phillips, M.S.1
Liu, Q.2
Hammond, H.A.3
Dugan, V.4
Hey, P.J.5
Caskey, C.J.6
Hess, J.F.7
-
38
-
-
0031033531
-
Near normalization of diurnal glucose concentrations by continuous administration of GLP-1 in subjects with NIDDM
-
RACHMAN, J., BARROW, B.A., LEVY, J.C. & TURNER, R.C. (1997). Near normalization of diurnal glucose concentrations by continuous administration of GLP-1 in subjects with NIDDM. Diabetologia, 40, 205-211.
-
(1997)
Diabetologia
, vol.40
, pp. 205-211
-
-
Rachman, J.1
Barrow, B.A.2
Levy, J.C.3
Turner, R.C.4
-
39
-
-
0037072573
-
NN2211: A long-acting glucagon-like peptide-1 derivative with anti-diabetic effects in glucose-intolerant pigs
-
RIBEL, U., LARSEN, M.O., ROLIN, B., CARR, R.D., WILKEN, M., STURIS, J., WESTERGAARD, L., DEACON, C.F. & KNUDSEN, L.B. (2002). NN2211: a long-acting glucagon-like peptide-1 derivative with anti-diabetic effects in glucose-intolerant pigs, Eur. J. Pharmacol., 451, 217-225.
-
(2002)
Eur. J. Pharmacol.
, vol.451
, pp. 217-225
-
-
Ribel, U.1
Larsen, M.O.2
Rolin, B.3
Carr, R.D.4
Wilken, M.5
Sturis, J.6
Westergaard, L.7
Deacon, C.F.8
Knudsen, L.B.9
-
40
-
-
0036784675
-
The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases β-cell mass in diabetic mice
-
ROLIN, B., LARSEN, M.O., GOTFREDSEN, C.F., DEACON, C.F., CARR, R.D., WILKEN, M. & KNUDSEN, L.B. (2002). The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases β-cell mass in diabetic mice. Am. J. Physiol. Endocrinol. Metab., 283, E745-E752.
-
(2002)
Am. J. Physiol. Endocrinol. Metab.
, vol.283
-
-
Rolin, B.1
Larsen, M.O.2
Gotfredsen, C.F.3
Deacon, C.F.4
Carr, R.D.5
Wilken, M.6
Knudsen, L.B.7
-
41
-
-
0029911348
-
Prevention of hyperglycemia in the Zucker diabetic fatty rat by treatment with metformin or troglitazone
-
SREENAN, S., STURIS, J., PUGH, W.L., BURANT, C.F. & POLONSKY, K.S. (1996). Prevention of hyperglycemia in the Zucker diabetic fatty rat by treatment with metformin or troglitazone. Am. J. Physiol., 271, E742-E747.
-
(1996)
Am. J. Physiol.
, vol.271
-
-
Sreenan, S.1
Sturis, J.2
Pugh, W.L.3
Burant, C.F.4
Polonsky, K.S.5
-
42
-
-
0037107429
-
Somatostatin inhibits glucagon-like peptide-1-induced insulin secretion and proliferation of RINm5F insulinoma cells
-
STARK, A. & MENTLEIN, R. (2002). Somatostatin inhibits glucagon-like peptide-1-induced insulin secretion and proliferation of RINm5F insulinoma cells. Regul. Pept., 108, 97-102.
-
(2002)
Regul. Pept.
, vol.108
, pp. 97-102
-
-
Stark, A.1
Mentlein, R.2
-
43
-
-
0028840490
-
Prevention of diabetes does not completely prevent insulin secretory defects in the ZDF Rat
-
STURIS, J., PUGH, W.L., TANG, J. & POLONSKY, K.S. (1995). Prevention of diabetes does not completely prevent insulin secretory defects in the ZDF Rat. Am. J. Physiol., 269, E786-E792.
-
(1995)
Am. J. Physiol.
, vol.269
-
-
Sturis, J.1
Pugh, W.L.2
Tang, J.3
Polonsky, K.S.4
-
44
-
-
0034456212
-
Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats
-
SZAYNA, M., DOYLE, M.E., BETKEY, J.A., HOLLOWAY, H.W., SPENCER, R.G., GREIG, N.H. & EGAN, J.M. (2000). Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats. Endocrinology, 141, 1936-1941.
-
(2000)
Endocrinology
, vol.141
, pp. 1936-1941
-
-
Szayna, M.1
Doyle, M.E.2
Betkey, J.A.3
Holloway, H.W.4
Spencer, R.G.5
Greig, N.H.6
Egan, J.M.7
-
45
-
-
0032976939
-
Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients
-
TOFT-NIELSEN, M.B., MADSBAD, S. & HOLST, J.J. (1999). Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients. Diabetes Care, 22, 1137-1143.
-
(1999)
Diabetes Care
, vol.22
, pp. 1137-1143
-
-
Toft-Nielsen, M.B.1
Madsbad, S.2
Holst, J.J.3
-
46
-
-
0032529111
-
Inhibitory effect of glucagon-like peptide-1 on small bowel motility
-
TOLESSA, T., GUTNIAK, M., HOLST, J.J., EFENDIC, S. & HELLSTRÖM, P.M. (1998). Inhibitory effect of glucagon-like peptide-1 on small bowel motility. J. Clin. Invest., 102, 764-774.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 764-774
-
-
Tolessa, T.1
Gutniak, M.2
Holst, J.J.3
Efendic, S.4
Hellström, P.M.5
-
47
-
-
0034111103
-
Effect of glucagon-like peptide 1(7-36) amide on glucose effectiveness and insulin action in people with type 2 diabetes
-
VELLA, A., SHAH, P., BASU, R., BASU, A., HOLST, J.J. & RIZZA, R.A. (2000). Effect of glucagon-like peptide 1(7-36) amide on glucose effectiveness and insulin action in people with type 2 diabetes. Diabetes, 49, 611-617.
-
(2000)
Diabetes
, vol.49
, pp. 611-617
-
-
Vella, A.1
Shah, P.2
Basu, R.3
Basu, A.4
Holst, J.J.5
Rizza, R.A.6
-
48
-
-
0027533758
-
Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man
-
WETTERGREN, A., SCHJOLDAGER, B., MORTENSEN, P.E., MYHRE, J., CHRISTIANSEN, J. & HOLST, J.J. (1993). Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man. Dig. Dis. Sci., 38, 665-673.
-
(1993)
Dig. Dis. Sci.
, vol.38
, pp. 665-673
-
-
Wettergren, A.1
Schjoldager, B.2
Mortensen, P.E.3
Myhre, J.4
Christiansen, J.5
Holst, J.J.6
-
49
-
-
0001042969
-
An immunoassay for the GLP-1 derivative NN2211
-
WILKEN, M., LARSEN, F.S., JUUL, A.-G., JENSEN, L.B. & RIBEL, U. (2000). An immunoassay for the GLP-1 derivative NN2211. Diabetologia, 43 (Suppl. 1), A148.
-
(2000)
Diabetologia
, vol.43
, Issue.1 SUPPL.
-
-
Wilken, M.1
Larsen, F.S.2
Juul, A.-G.3
Jensen, L.B.4
Ribel, U.5
-
50
-
-
0030068620
-
Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: Effects of exogenous GLP-1 (7-36)amide in type 2 (noninsulin-dependent) diabetic patients
-
WILLMS, B., WERNER, J., HOLST, J.J., ØRSKOV, C., CREUTZFELDT, W. & NAUCK, M. (1996). Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous GLP-1 (7-36)amide in type 2 (noninsulin-dependent) diabetic patients. J. Clin. Endocrinol. Metab., 81, 327-332.
-
(1996)
J. Clin. Endocrinol. Metab.
, vol.81
, pp. 327-332
-
-
Willms, B.1
Werner, J.2
Holst, J.J.3
Ørskov, C.4
Creutzfeldt, W.5
Nauck, M.6
-
51
-
-
0033513455
-
Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats
-
XU, G., STOFFERS, D.A., HABENER, J.F. & BONNER-WEIR, S. (1999). Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats. Diabetes, 48, 2270-2276.
-
(1999)
Diabetes
, vol.48
, pp. 2270-2276
-
-
Xu, G.1
Stoffers, D.A.2
Habener, J.F.3
Bonner-Weir, S.4
-
52
-
-
0037045845
-
GLP-1 treatment for 6 weeks improves glycaemic control, insulin sensitivity and β-cell function in type 2 diabetic patients
-
ZANDER, M., MADSBAD, S. & HOLST, J.J. (2002). GLP-1 treatment for 6 weeks improves glycaemic control, insulin sensitivity and β-cell function in type 2 diabetic patients. Lancet, 359, 824-830.
-
(2002)
Lancet
, vol.359
, pp. 824-830
-
-
Zander, M.1
Madsbad, S.2
Holst, J.J.3
|