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Volumn 15, Issue 5, 2013, Pages 417-426

No evidence of drug-induced pancreatitis in rats treated with exenatide for 13weeks

Author keywords

Exenatide; Exocrine pancreas; ZDF rat

Indexed keywords

AMYLASE; EXENDIN 4; GLUCOSE; HEMOGLOBIN A1C; INSULIN; TRIACYLGLYCEROL LIPASE;

EID: 84876332227     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/dom.12040     Document Type: Article
Times cited : (51)

References (38)
  • 1
    • 34548803017 scopus 로고    scopus 로고
    • Incretin-based treatment of type 2 diabetes: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors
    • Deacon CF. Incretin-based treatment of type 2 diabetes: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors. Diabetes Obes Metab 2007; 9: 23-31.
    • (2007) Diabetes Obes Metab , vol.9 , pp. 23-31
    • Deacon, C.F.1
  • 2
    • 33846006173 scopus 로고    scopus 로고
    • The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
    • Drucker DJ, Nauck MA. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet 2006; 368: 1696-1705.
    • (2006) Lancet , vol.368 , pp. 1696-1705
    • Drucker, D.J.1    Nauck, M.A.2
  • 3
    • 84864285795 scopus 로고    scopus 로고
    • Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
    • Inzucchi SE, Bergenstal RM, Buse JB et al. Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia 2012; 55: 1577-1596.
    • (2012) Diabetologia , vol.55 , pp. 1577-1596
    • Inzucchi, S.E.1    Bergenstal, R.M.2    Buse, J.B.3
  • 4
    • 59449101432 scopus 로고    scopus 로고
    • Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial
    • Garber A, Henry R, Ratner R et al. Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial. Lancet 2009; 373: 473-481.
    • (2009) Lancet , vol.373 , pp. 473-481
    • Garber, A.1    Henry, R.2    Ratner, R.3
  • 5
    • 33646354927 scopus 로고    scopus 로고
    • Exenatide (exendin-4)-induced pancreatitis: a case report
    • Denker PS, Dimarco PE. Exenatide (exendin-4)-induced pancreatitis: a case report. Diabetes Care 2006; 29: 471.
    • (2006) Diabetes Care , vol.29 , pp. 471
    • Denker, P.S.1    Dimarco, P.E.2
  • 6
    • 84872746074 scopus 로고    scopus 로고
    • Safety and tolerability of exenatide once weekly in patients with type 2 diabetes: an integrated analysis of 4328 patients
    • MacConell L, Gurney K, Malloy J, Zhang E, Zhou M, Chen S. Safety and tolerability of exenatide once weekly in patients with type 2 diabetes: an integrated analysis of 4328 patients. Diabetes 2012; 61: A598.
    • (2012) Diabetes , vol.61
    • MacConell, L.1    Gurney, K.2    Malloy, J.3    Zhang, E.4    Zhou, M.5    Chen, S.6
  • 8
    • 84857573175 scopus 로고    scopus 로고
    • Case report of acute necrotizing pancreatitis associated with combination treatment of sitagliptin and exenatide
    • Iyer SN, Drake AJ 3rd, West RL, Mendez CE, Tanenberg RJ. Case report of acute necrotizing pancreatitis associated with combination treatment of sitagliptin and exenatide. Endocr Pract 2012; 18: e10-e13.
    • (2012) Endocr Pract , vol.18
    • Iyer, S.N.1    Drake, III.A.J.2    West, R.L.3    Mendez, C.E.4    Tanenberg, R.J.5
  • 9
    • 79959559653 scopus 로고    scopus 로고
    • Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies
    • Elashoff M, Matveyenko AV, Gier B, Elashoff R, Butler PC. Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies. Gastroenterology 2011; 141: 150-156.
    • (2011) Gastroenterology , vol.141 , pp. 150-156
    • Elashoff, M.1    Matveyenko, A.V.2    Gier, B.3    Elashoff, R.4    Butler, P.C.5
  • 10
    • 65949111736 scopus 로고    scopus 로고
    • Increased risk of acute pancreatitis and biliary disease observed in patients with type 2 diabetes: a retrospective cohort study
    • Noel RA, Braun DK, Patterson RE, Bloomgren GL. Increased risk of acute pancreatitis and biliary disease observed in patients with type 2 diabetes: a retrospective cohort study. Diabetes Care 2009; 32: 834-838.
    • (2009) Diabetes Care , vol.32 , pp. 834-838
    • Noel, R.A.1    Braun, D.K.2    Patterson, R.E.3    Bloomgren, G.L.4
  • 12
    • 78649658112 scopus 로고    scopus 로고
    • Exenatide does not evoke pancreatitis and attenuates chemically induced pancreatitis in normal and diabetic rodents
    • Tatarkiewicz K, Smith PA, Sablan EJ et al. Exenatide does not evoke pancreatitis and attenuates chemically induced pancreatitis in normal and diabetic rodents. Am J Physiol Endocrinol Metab 2010; 299: E1076-E1086.
    • (2010) Am J Physiol Endocrinol Metab , vol.299
    • Tatarkiewicz, K.1    Smith, P.A.2    Sablan, E.J.3
  • 13
    • 70349120958 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor activation modulates pancreatitis-associated gene expression but does not modify the susceptibility to experimental pancreatitis in mice
    • Koehler JA, Baggio LL, Lamont BJ, Ali S, Drucker DJ. Glucagon-like peptide-1 receptor activation modulates pancreatitis-associated gene expression but does not modify the susceptibility to experimental pancreatitis in mice. Diabetes 2009; 58: 2148-2161.
    • (2009) Diabetes , vol.58 , pp. 2148-2161
    • Koehler, J.A.1    Baggio, L.L.2    Lamont, B.J.3    Ali, S.4    Drucker, D.J.5
  • 14
    • 84860577431 scopus 로고    scopus 로고
    • The human GLP-1 analog liraglutide and the pancreas: evidence for the absence of structural pancreatic changes in three species
    • Nyborg NC, Molck AM, Madsen LW, Knudsen LB. The human GLP-1 analog liraglutide and the pancreas: evidence for the absence of structural pancreatic changes in three species. Diabetes 2012; 61: 1243-1249.
    • (2012) Diabetes , vol.61 , pp. 1243-1249
    • Nyborg, N.C.1    Molck, A.M.2    Madsen, L.W.3    Knudsen, L.B.4
  • 15
    • 84863950236 scopus 로고    scopus 로고
    • The effects of 13weeks of liraglutide treatment on endocrine and exocrine pancreas in male and female ZDF-rats : no evidence of drug induced pancreatitis
    • Vrang N, Jelsing J, Simonsen L et al. The effects of 13weeks of liraglutide treatment on endocrine and exocrine pancreas in male and female ZDF-rats : no evidence of drug induced pancreatitis. Am J Physiol Endocrinol Metab 2012; 303: E253-E264.
    • (2012) Am J Physiol Endocrinol Metab , vol.303
    • Vrang, N.1    Jelsing, J.2    Simonsen, L.3
  • 16
    • 72449157026 scopus 로고    scopus 로고
    • Biochemical and histological effects of exendin-4 (exenatide) on the rat pancreas
    • Nachnani JS, Bulchandani DG, Nookala A et al. Biochemical and histological effects of exendin-4 (exenatide) on the rat pancreas. Diabetologia 2010; 53: 153-159.
    • (2010) Diabetologia , vol.53 , pp. 153-159
    • Nachnani, J.S.1    Bulchandani, D.G.2    Nookala, A.3
  • 17
    • 84860567470 scopus 로고    scopus 로고
    • Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model
    • Gier B, Matveyenko AV, Kirakossian D, Dawson D, Dry SM, Butler PC. Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model. Diabetes 2012; 61: 1250-1262.
    • (2012) Diabetes , vol.61 , pp. 1250-1262
    • Gier, B.1    Matveyenko, A.V.2    Kirakossian, D.3    Dawson, D.4    Dry, S.M.5    Butler, P.C.6
  • 19
    • 0032739213 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 does not mediate amylase release from AR42J cells
    • Zhou J, Montrose-Rafizadeh C, Janczewski AM et al. Glucagon-like peptide-1 does not mediate amylase release from AR42J cells. J Cell Physiol 1999; 181: 470-478.
    • (1999) J Cell Physiol , vol.181 , pp. 470-478
    • Zhou, J.1    Montrose-Rafizadeh, C.2    Janczewski, A.M.3
  • 21
    • 78649911161 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of exenatide extended-release after single and multiple dosing
    • Fineman M, Flanagan S, Taylor K et al. Pharmacokinetics and pharmacodynamics of exenatide extended-release after single and multiple dosing. Clin Pharmacokinet 2011; 50: 65-74.
    • (2011) Clin Pharmacokinet , vol.50 , pp. 65-74
    • Fineman, M.1    Flanagan, S.2    Taylor, K.3
  • 22
    • 23944488440 scopus 로고    scopus 로고
    • Dose-response for glycaemic and metabolic changes 28days after single injection of long-acting release exenatide in diabetic fatty Zucker rats
    • Gedulin BR, Smith P, Prickett KS et al. Dose-response for glycaemic and metabolic changes 28days after single injection of long-acting release exenatide in diabetic fatty Zucker rats. Diabetologia 2005; 48: 1380-1385.
    • (2005) Diabetologia , vol.48 , pp. 1380-1385
    • Gedulin, B.R.1    Smith, P.2    Prickett, K.S.3
  • 23
    • 0032908654 scopus 로고    scopus 로고
    • Glucose-lowering and insulin-sensitizing actions of exendin-4: studies in obese diabetic (ob/ob, db/db) mice, diabetic fatty Zucker rats, and diabetic rhesus monkeys (Macaca mulatta)
    • Young AA, Gedulin BR, Bhavsar S et al. Glucose-lowering and insulin-sensitizing actions of exendin-4: studies in obese diabetic (ob/ob, db/db) mice, diabetic fatty Zucker rats, and diabetic rhesus monkeys (Macaca mulatta). Diabetes 1999; 48: 1026-1034.
    • (1999) Diabetes , vol.48 , pp. 1026-1034
    • Young, A.A.1    Gedulin, B.R.2    Bhavsar, S.3
  • 24
    • 0033513455 scopus 로고    scopus 로고
    • Exendin-4 stimulates both β-cell replication and neogenesis, resulting in increased β-cell mass and improved glucose tolerance in diabetic rats
    • Xu G, Stoffers DA, Habener JF, Bonner-Weir S. Exendin-4 stimulates both β-cell replication and neogenesis, resulting in increased β-cell mass and improved glucose tolerance in diabetic rats. Diabetes 1999; 48: 2270-2276.
    • (1999) Diabetes , vol.48 , pp. 2270-2276
    • Xu, G.1    Stoffers, D.A.2    Habener, J.F.3    Bonner-Weir, S.4
  • 25
    • 0034032317 scopus 로고    scopus 로고
    • Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas
    • Stoffers DA, Kieffer TJ, Hussain MA et al. Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas. Diabetes 2000; 49: 741-748.
    • (2000) Diabetes , vol.49 , pp. 741-748
    • Stoffers, D.A.1    Kieffer, T.J.2    Hussain, M.A.3
  • 26
    • 0036312680 scopus 로고    scopus 로고
    • Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the β-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4
    • Tourrel C, Bailbe D, Lacorne M, Meile MJ, Kergoat M, Portha B. Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the β-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4. Diabetes 2002; 51: 1443-1452.
    • (2002) Diabetes , vol.51 , pp. 1443-1452
    • Tourrel, C.1    Bailbe, D.2    Lacorne, M.3    Meile, M.J.4    Kergoat, M.5    Portha, B.6
  • 27
    • 0036828227 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats
    • Farilla L, Hui H, Bertolotto C et al. Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats. Endocrinology 2002; 143: 4397-4408.
    • (2002) Endocrinology , vol.143 , pp. 4397-4408
    • Farilla, L.1    Hui, H.2    Bertolotto, C.3
  • 30
    • 19944418280 scopus 로고    scopus 로고
    • Pathophysiology of acute pancreatitis
    • Bhatia M, Wong FL, Cao Y et al. Pathophysiology of acute pancreatitis. Pancreatology 2005; 5: 132-144.
    • (2005) Pancreatology , vol.5 , pp. 132-144
    • Bhatia, M.1    Wong, F.L.2    Cao, Y.3
  • 32
    • 34250635159 scopus 로고    scopus 로고
    • GLP-1 receptor expression in human tumors and human normal tissues: potential for in vivo targeting
    • Korner M, Stockli M, Waser B, Reubi JC. GLP-1 receptor expression in human tumors and human normal tissues: potential for in vivo targeting. J Nucl Med 2007; 48: 736-743.
    • (2007) J Nucl Med , vol.48 , pp. 736-743
    • Korner, M.1    Stockli, M.2    Waser, B.3    Reubi, J.C.4
  • 33
    • 34250732525 scopus 로고    scopus 로고
    • [Lys40(Ahx-DTPA-111In)NH2]exendin-4, a very promising ligand for glucagon-like peptide-1 (GLP-1) receptor targeting
    • Wild D, Behe M, Wicki A et al. [Lys40(Ahx-DTPA-111In)NH2]exendin-4, a very promising ligand for glucagon-like peptide-1 (GLP-1) receptor targeting. J Nucl Med 2006; 47: 2025-2033.
    • (2006) J Nucl Med , vol.47 , pp. 2025-2033
    • Wild, D.1    Behe, M.2    Wicki, A.3
  • 34
    • 0036232690 scopus 로고    scopus 로고
    • Use of the incretin hormone glucagon-like peptide-1 (GLP-1) for the detection of insulinomas: initial experimental results
    • Gotthardt M, Fischer M, Naeher I et al. Use of the incretin hormone glucagon-like peptide-1 (GLP-1) for the detection of insulinomas: initial experimental results. Eur J Nucl Med Mol Imaging 2002; 29: 597-606.
    • (2002) Eur J Nucl Med Mol Imaging , vol.29 , pp. 597-606
    • Gotthardt, M.1    Fischer, M.2    Naeher, I.3
  • 36
    • 72449148137 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 therapy and the exocrine pancreas: innocent bystander or friendly fire?
    • Butler PC, Matveyenko AV, Dry S, Bhushan A, Elashoff R. Glucagon-like peptide-1 therapy and the exocrine pancreas: innocent bystander or friendly fire? Diabetologia 2010; 53: 1-6.
    • (2010) Diabetologia , vol.53 , pp. 1-6
    • Butler, P.C.1    Matveyenko, A.V.2    Dry, S.3    Bhushan, A.4    Elashoff, R.5
  • 38
    • 77958110361 scopus 로고    scopus 로고
    • Characterization of human pancreatic progenitor cells
    • Noguchi H, Naziruddin B, Jackson A et al. Characterization of human pancreatic progenitor cells. Cell Transplant 2010; 19: 879-886.
    • (2010) Cell Transplant , vol.19 , pp. 879-886
    • Noguchi, H.1    Naziruddin, B.2    Jackson, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.