Inducible synthesis of the mitomycin C resistance gene product (MCRA) from Streptomyces lavendulae

Gene

Volumn 175, Issue 1-2, 1996, Pages 261-267

  August, Paul R ^a,b   Rahn, John A ^a   Flickinger, Michael C ^a   Sherman, David H ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Cellular self protection; Drug inducible production; Enzyme linked immunosorbent assay; Mitomycins; Streptomyces lividans

Indexed keywords

BACTERIAL PROTEIN; MITOMYCIN A; MITOMYCIN B; MITOMYCIN C; MITOMYCIN D; PORFIROMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOBLOTTING; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; STREPTOMYCES LAVENDULAE; STREPTOMYCES LIVIDANS; STRUCTURE ACTIVITY RELATION;

BACTERIA (MICROORGANISMS); STREPTOMYCES LAVENDULAE; STREPTOMYCES LIVIDANS;

EID: 0030579148     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-1119(96)00172-2     Document Type: Article

References (22)

1. August, P.R., Flickinger, M.C. and Sherman, D.H. (1994) Cloning and analysis of a locus (mcr) involved in mitomycin C resistance in Streptomyces lavendulae. J. Bacteriol. 176, 4448-4454.
2. Beijnen, J.H., Lingeman, H., Van Munster, H.A. and Underberg, W.J.M. (1986) Mitomycin antitumour agents: a review of their physico-chemical and analytical properties and stability. J. Pharm. Biomed. Anal. 4, 275-295.
3. Bjerrum, O.J. and Schafer-Nielsen, C. (1986) In: Dunn, M.J. (Ed.), Analytical Electrophoresis. Verlag Chemie, Weinheim, Germany, p. 315.
4. Cundliffe, E. (1989) How antibiotic-producing organisms avoid suicide. Annu. Rev. Microbiol. 43, 207-233.
5. Cundliffe, E. (1992) Self-protection mechanisms in antibiotic producers. In: Secondary Metabolites: Their Function and Evolution. Ciba Foundation Symposium, 171. Wiley, Chichester, UK, pp. 199-214.
6. Davies, J. (1986) A new look at antibiotic resistance. FEMS Microbiol. Lett. 39, 363-371.
7. Hata, T., Sano, Y., Sugawara, R., Matsumae, A., Kanamori, K., Shima, T. and Hoshi, T. (1956) Mitomycin, a new antibiotic from Streptomyces. J. Antibiot. Ser. A. 9, 141-146.
8. Holmes, D.J., Caso, J.L. and Thompson, C.J. (1993) Autogenous transcriptional activation of a thiostrepton-induced gene in Streptomyces lividans. EMBO J. 12, 3183-3191.
9. Hopwood, D.A., Bibb, M.J., Chater, K.F., Kieser, T., Bruton, C.J., Kieser, H.M., Lydiate, D.J., Smith, C.P., Ward, J.M. and Schrempf, H. (1985) In Genetic Manipulation of Streptomyces. A Laboratory Manual. John Innes Foundation, Norwich, UK.
10. Katz, E., Thompson, C.J. and Hopwood, D.A. (1983) Cloning and expression of the tyrosinase gene from Streptomyces antibioticus in Streptomyces lividans. J. Gen. Microbiol. 129, 2703-2714.
11. Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
12. Mandwal, A.K., Subramainian, P.M., Bhatia, M.C. and Kapil, R.S. (1985) Production of mitomycin C and porfiromycin by Streptomyces species. J. Nat. Prod. 48, 334-335.
13. Murakami, T., Holt, T.G. and Thompson, C.J. (1989) Thiostrepton-induced gene expression in Streptomyces lividans. J. Bacteriol. 171, 1459-1466.
14. Quinones, A., Juterbock, W.R. and Messer, W. (1991a) Expression of dnaA gene of Escherichia coli is inducible by DNA damage. Mol. Gen. Genet. 227, 9-16.
15. Quinones, A., Juterbock, W.R. and Messer, W. (1991b) DNA lesions that block DNA replication are responsible for the dnaA induction caused by DNA damage. Mol. Gen. Genet. 231, 81-87.
16. Silver, S. and Walserhaug, M. (1992) Gene regulation of plasmid-and chromosome-determined inorganic ion transport in bacteria. Microbiol. Rev. 56, 195-228.
17. Summers, A.O. (1992) Untwist and shout: a heavy metal-responsive transcriptional regulator. J. Bacteriol. 174, 3097-3101.
18. Wakaki, S., Marumo, H., Tomioka, K., Shimizu, G., Kato, E., Damada, H., Kudo, S. and Fujimoto, Y. (1958) Isolation of new fractions of antitumor mitomycins. Antibiot. Chemother. 8, 228-240.
19. Webb, J.S., Cosulich, D.B., Mowat, J.H., Patrick, J.B., Broschard, R.W., Meyer, W.E., Williams, R.P., Wolf, C.F., Fulmor, W., Pidacks, C. and Lancaster, J.E. (1962a) The structures of mitomycins A, B, C and porfiromycin - Part I. J. Am. Chem. Soc. 84, 3185-3187.
20. Webb, J.S., Cosulich, D.B., Mowat, J.H., Patrick, J.B., Broschard, R.W., Meyer, W.E., Williams, R.P., Wolf, C.F., Fulmor, W., Pidacks, C. and Lancaster, J.E. (1962b) The structures of mitomycins A, B, C and porfiromycin - Part II. J. Am. Chem. Soc. 84, 3187-3188.
21. Yamagata, H., Kodama, T. and Minoda, Y. (1988) Mode of action for mitomycin C inactivating factors of Pseudomanas convexa 4-87. Agric. Biol. Chem. 52, 3093-3097.
22. Zakrzewska-Czerwinska, J., Nardman, J. and Schrempf, H. (1994) Inducible transcription of the dnaA gene from Streptomyces lividans 66. Mol. Gen. Genet. 242, 440-447.