-
1
-
-
80052539042
-
Complete genome sequence of Streptomyces cattleya NRRL 8057, a producer of antibiotics and fluorometabolites
-
1:CAS:528:DC%2BC3MXhtFKntrzI 21868806 10.1128/JB.05583-11 3165681
-
Barbe V, Bouzon M, Mangenot S, Badet B, Poulain J, Segurens B, Vallenet D, Marlière P, Weissenbach J (2011) Complete genome sequence of Streptomyces cattleya NRRL 8057, a producer of antibiotics and fluorometabolites. J Bacteriol 193:5055-5056
-
(2011)
J Bacteriol
, vol.193
, pp. 5055-5056
-
-
Barbe, V.1
Bouzon, M.2
Mangenot, S.3
Badet, B.4
Poulain, J.5
Segurens, B.6
Vallenet, D.7
Marlière, P.8
Weissenbach, J.9
-
2
-
-
0037046560
-
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)
-
12000953 10.1038/417141a
-
Bentley SD, Chater KF, Cerdeno-Tarraga AM, Challis GL, Thomson NR, James KD, Harris DE, Quail MA, Kieser H, Harper D, Bateman A, Brown S, Chandra G, Chen CW, Collins M, Cronin A, Fraser A, Goble A, Hidalgo J, Hornsby T, Howarth S, Huang CH, Kieser T, Larke L, Murphy L, Oliver K, O'Neil S, Rabbinowitsch E, Rajandream MA, Rutherford K, Rutter S, Seeger K, Saunders D, Sharp S, Squares R, Squares S, Taylor K, Warren T, Wietzorrek A, Woodward J, Barrell BG, Parkhill J, Hopwood DA (2002) Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature 417:141-147
-
(2002)
Nature
, vol.417
, pp. 141-147
-
-
Bentley, S.D.1
Chater, K.F.2
Cerdeno-Tarraga, A.M.3
Challis, G.L.4
Thomson, N.R.5
James, K.D.6
Harris, D.E.7
Quail, M.A.8
Kieser, H.9
Harper, D.10
Bateman, A.11
Brown, S.12
Chandra, G.13
Chen, C.W.14
Collins, M.15
Cronin, A.16
Fraser, A.17
Goble, A.18
Hidalgo, J.19
Hornsby, T.20
Howarth, S.21
Huang, C.H.22
Kieser, T.23
Larke, L.24
Murphy, L.25
Oliver, K.26
O'Neil, S.27
Rabbinowitsch, E.28
Rajandream, M.A.29
Rutherford, K.30
Rutter, S.31
Seeger, K.32
Saunders, D.33
Sharp, S.34
Squares, R.35
Squares, S.36
Taylor, K.37
Warren, T.38
Wietzorrek, A.39
Woodward, J.40
Barrell, B.G.41
Parkhill, J.42
Hopwood, D.A.43
more..
-
3
-
-
75749150917
-
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions
-
1:CAS:528:DC%2BC3cXovVWksA%3D%3D 20064060 10.1094/MPMI-23-2-0161
-
Bignell DRD, Seipke RF, Huguet-Tapia JC, Chambers AH, Parry RJ, Loria R (2010) Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions. Mol Plant Microbe Interact 23:161-175
-
(2010)
Mol Plant Microbe Interact
, vol.23
, pp. 161-175
-
-
Bignell, D.R.D.1
Seipke, R.F.2
Huguet-Tapia, J.C.3
Chambers, A.H.4
Parry, R.J.5
Loria, R.6
-
4
-
-
0018386220
-
Avermectins, new family of potent anthelmintic agents: Producing organism and fermentation
-
1:CAS:528:DyaE1MXktlOntro%3D 464561 10.1128/AAC.15.3.361 352666
-
Burg RW, Miller BM, Baker EE, Birnbaum J, Currie SA, Hartman R, Kong YL, Monaghan RL, Olson G, Putter I, Tunac JB, Wallick H, Stapley EO, Oiwa R, Omura S (1979) Avermectins, new family of potent anthelmintic agents: producing organism and fermentation. Antimicrob Agents Chemother 15:361-367
-
(1979)
Antimicrob Agents Chemother
, vol.15
, pp. 361-367
-
-
Burg, R.W.1
Miller, B.M.2
Baker, E.E.3
Birnbaum, J.4
Currie, S.A.5
Hartman, R.6
Kong, Y.L.7
Monaghan, R.L.8
Olson, G.9
Putter, I.10
Tunac, J.B.11
Wallick, H.12
Stapley, E.O.13
Oiwa, R.14
Omura, S.15
-
5
-
-
33749474044
-
Geosmin biosynthesis in Streptomyces avermitilis
-
1:CAS:528:DC%2BD28XpvVGitb0%3D 17080683 10.1038/ja.2006.66
-
Cane DE, He X, Kobayashi S, Omura S, Ikeda H (2006) Geosmin biosynthesis in Streptomyces avermitilis. J Antibiot 59:471-479
-
(2006)
J Antibiot
, vol.59
, pp. 471-479
-
-
Cane, D.E.1
He, X.2
Kobayashi, S.3
Omura, S.4
Ikeda, H.5
-
6
-
-
33847674077
-
Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtlF, a short-chain dehydrogenase from Streptomyces avermitilis, and identification of a new biosynthetic intermediate
-
17178094 10.1016/j.abb.2006.11.016 1857356
-
Cane DE, You Z, Omura S, Ikeda H (2007) Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtlF, a short-chain dehydrogenase from Streptomyces avermitilis, and identification of a new biosynthetic intermediate. Arch Biochem Biophys 459:233-240
-
(2007)
Arch Biochem Biophys
, vol.459
, pp. 233-240
-
-
Cane, D.E.1
You, Z.2
Omura, S.3
Ikeda, H.4
-
7
-
-
0032443691
-
Characterization of the genes for the biosynthesis of the compatible solute ectoine in the moderately halophilic bacterium Halomonas elongata DSM 3043
-
9924816 10.1016/S0723-2020(98)80060-X
-
Cánovas D, Vargas C, Calderon MI, Ventosa A, Nieto JJ (1998) Characterization of the genes for the biosynthesis of the compatible solute ectoine in the moderately halophilic bacterium Halomonas elongata DSM 3043. Syst Appl Microbiol 21:487-497
-
(1998)
Syst Appl Microbiol
, vol.21
, pp. 487-497
-
-
Cánovas, D.1
Vargas, C.2
Calderon, M.I.3
Ventosa, A.4
Nieto, J.J.5
-
8
-
-
0023886117
-
LL-F28249 antibiotic complex: A new family of antiparasitic macrocyclic lactones: Isolation, characterization and structures of LL-F28249 α, β, γ, λ
-
1:CAS:528:DyaL1cXkvV2gur0%3D 3372359 10.7164/antibiotics.41.519
-
Carter GT, Nietsche JA, Hertz MR, Williams DR, Siegel MM, Morton GO, James JC, Borders DB (1988) LL-F28249 antibiotic complex: a new family of antiparasitic macrocyclic lactones: isolation, characterization and structures of LL-F28249 α, β, γ, λ. J Antibiot 41:519-529
-
(1988)
J Antibiot
, vol.41
, pp. 519-529
-
-
Carter, G.T.1
Nietsche, J.A.2
Hertz, M.R.3
Williams, D.R.4
Siegel, M.M.5
Morton, G.O.6
James, J.C.7
Borders, D.B.8
-
9
-
-
77954303579
-
Genome mining in Streptomyces avermitilis: Cloning and characterization of SAV-76, the synthase for a new sesquiterpene, avermitilol
-
1:CAS:528:DC%2BC3cXntlWrtb8%3D 20536237 10.1021/ja103087w 2904616
-
Chou WKW, Fanizza I, Uchiyama T, Komatsu M, Ikeda H, Cane DE (2010) Genome mining in Streptomyces avermitilis: cloning and characterization of SAV-76, the synthase for a new sesquiterpene, avermitilol. J Am Chem Soc 132:8850-8851
-
(2010)
J Am Chem Soc
, vol.132
, pp. 8850-8851
-
-
Chou, W.K.W.1
Fanizza, I.2
Uchiyama, T.3
Komatsu, M.4
Ikeda, H.5
Cane, D.E.6
-
10
-
-
0023631215
-
Tn4556, a 6.8-kilobase-pair transposable element of Streptomyces fradiae
-
1:CAS:528:DyaL2sXlvFWqsbg%3D 2820925 213805
-
Chung ST (1987) Tn4556, a 6.8-kilobase-pair transposable element of Streptomyces fradiae. J Bacteriol 169:4436-4441
-
(1987)
J Bacteriol
, vol.169
, pp. 4436-4441
-
-
Chung, S.T.1
-
11
-
-
0027965019
-
A Streptomyces avermitilis gene encoding a 4-hydroxyphenylpyruvic acid dioxygenase-like protein that directs the production of homogentisic acid and an ochronotic pigment in Escherichia coli
-
1:CAS:528:DyaK2cXmt1egu78%3D 8071207 196716
-
Denoya CD, Skinner DD, Morgenstern MR (1994) A Streptomyces avermitilis gene encoding a 4-hydroxyphenylpyruvic acid dioxygenase-like protein that directs the production of homogentisic acid and an ochronotic pigment in Escherichia coli. J Bacteriol 176:5312-5319
-
(1994)
J Bacteriol
, vol.176
, pp. 5312-5319
-
-
Denoya, C.D.1
Skinner, D.D.2
Morgenstern, M.R.3
-
12
-
-
62149143362
-
Engineered production of iso-migrastatin in heterologous Streptomyces hosts
-
1:CAS:528:DC%2BD1MXjsFWqt7o%3D 19010685 10.1016/j.bmc.2008.10.074 3075207
-
Feng Z, Wang L, Rajski SR, Xu Z, Coeffet-LeGal MF, Shen B (2009) Engineered production of iso-migrastatin in heterologous Streptomyces hosts. Bioorg Med Chem 17:2147-2153
-
(2009)
Bioorg Med Chem
, vol.17
, pp. 2147-2153
-
-
Feng, Z.1
Wang, L.2
Rajski, S.R.3
Xu, Z.4
Coeffet-Legal, M.F.5
Shen, B.6
-
13
-
-
70349179206
-
Analysis of two additional signaling molecules in Streptomyces coelicolor and the development of a butyrolactone-specific reporter system
-
1:CAS:528:DC%2BD1MXhtFynsLrM 19778723 10.1016/j.chembiol.2009.08.010
-
Hsiao NH, Nakayama S, Merlo ME, Vries M, Bunet R, Kitani S, Nihira T, Takano T (2009) Analysis of two additional signaling molecules in Streptomyces coelicolor and the development of a butyrolactone-specific reporter system. Chem Biol 16:951-960
-
(2009)
Chem Biol
, vol.16
, pp. 951-960
-
-
Hsiao, N.H.1
Nakayama, S.2
Merlo, M.E.3
Vries, M.4
Bunet, R.5
Kitani, S.6
Nihira, T.7
Takano, T.8
-
14
-
-
0023543591
-
Genetic studies of avermectin biosynthesis in Streptomyces avermitilis
-
1:CAS:528:DyaL1cXjsVKltg%3D%3D 3680172 214006
-
Ikeda H, Kotaki H, Omura S (1987) Genetic studies of avermectin biosynthesis in Streptomyces avermitilis. J Bacteriol 169:5615-5621
-
(1987)
J Bacteriol
, vol.169
, pp. 5615-5621
-
-
Ikeda, H.1
Kotaki, H.2
Omura, S.3
-
15
-
-
0027410919
-
Transposon mutagenesis by Tn4560 and applications with avermectin-producing Streptomyces avermitilis
-
1:CAS:528:DyaK3sXit1Kkt7s%3D 8384619 204307
-
Ikeda H, Takada Y, Pang CH, Tanaka H, Omura S (1993) Transposon mutagenesis by Tn4560 and applications with avermectin-producing Streptomyces avermitilis. J Bacteriol 175:2077-2082
-
(1993)
J Bacteriol
, vol.175
, pp. 2077-2082
-
-
Ikeda, H.1
Takada, Y.2
Pang, C.H.3
Tanaka, H.4
Omura, S.5
-
16
-
-
0033578297
-
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis
-
1:CAS:528:DyaK1MXlsVyms74%3D 10449723 10.1073/pnas.96.17.9509 22239
-
Ikeda H, Nonomiya T, Usami M, Ohta T, Omura S (1999) Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis. Proc Natl Acad Sci U S A 96:9509-9514
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 9509-9514
-
-
Ikeda, H.1
Nonomiya, T.2
Usami, M.3
Ohta, T.4
Omura, S.5
-
17
-
-
0038561132
-
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis
-
12692562 10.1038/nbt820
-
Ikeda H, Ishikawa J, Hanamoto A, Shinose M, Kikuchi H, Shiba T, Sakaki Y, Hattori M, Omura S (2003) Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis. Nat Biotechnol 21:526-531
-
(2003)
Nat Biotechnol
, vol.21
, pp. 526-531
-
-
Ikeda, H.1
Ishikawa, J.2
Hanamoto, A.3
Shinose, M.4
Kikuchi, H.5
Shiba, T.6
Sakaki, Y.7
Hattori, M.8
Omura, S.9
-
18
-
-
0023787348
-
The structure and biosynthesis of new tetrahydropyrimidine derivatives in actinomycin D producer Streptomyces parvulus
-
1:CAS:528:DyaL1cXmtVyjt7Y%3D 2903148
-
Inbar L, Lapidot A (1988) The structure and biosynthesis of new tetrahydropyrimidine derivatives in actinomycin D producer Streptomyces parvulus. J Biol Chem 263:16014-16022
-
(1988)
J Biol Chem
, vol.263
, pp. 16014-16022
-
-
Inbar, L.1
Lapidot, A.2
-
19
-
-
84864697583
-
Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B0171
-
1:CAS:528:DC%2BC38XotlSlu7c%3D 10.1007/s00253-012-3973-8
-
Inokoshi J, Matsuhama M, Miyake M, Ikeda H, Tomoda H (2012) Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B0171. Appl Microb Biotechnol 95:451-460
-
(2012)
Appl Microb Biotechnol
, vol.95
, pp. 451-460
-
-
Inokoshi, J.1
Matsuhama, M.2
Miyake, M.3
Ikeda, H.4
Tomoda, H.5
-
20
-
-
67650034392
-
Genome mining in Streptomyces avermitilis: A biochemical Baeyer-Villiger reaction and discovery of a new branch of the pentalenolactone family tree
-
1:CAS:528:DC%2BD1MXnt1Ogur0%3D 19485417 10.1021/bi900766w 2747811
-
Jiang J, Tetzlaff CN, Takamatsu S, Iwatsuki M, Komatsu M, Ikeda H, Cane DE (2009) Genome mining in Streptomyces avermitilis: a biochemical Baeyer-Villiger reaction and discovery of a new branch of the pentalenolactone family tree. Biochemistry 48:6431-6440
-
(2009)
Biochemistry
, vol.48
, pp. 6431-6440
-
-
Jiang, J.1
Tetzlaff, C.N.2
Takamatsu, S.3
Iwatsuki, M.4
Komatsu, M.5
Ikeda, H.6
Cane, D.E.7
-
21
-
-
80053620569
-
Avenolide, a Streptomyces hormone controlling antibiotic production in Streptomyces avermitilis
-
1:CAS:528:DC%2BC3MXht1Kmtb3E 21930904 10.1073/pnas.1113908108 3182739
-
Kitani S, Miyamoto KT, Takamatsu S, Herawati E, Iguchi H, Nishitomi K, Uchida M, Nagamitsu T, Omura S, Ikeda H, Nihira T (2011) Avenolide, a Streptomyces hormone controlling antibiotic production in Streptomyces avermitilis. Proc Natl Acad Sci U S A 108:16410-16415
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 16410-16415
-
-
Kitani, S.1
Miyamoto, K.T.2
Takamatsu, S.3
Herawati, E.4
Iguchi, H.5
Nishitomi, K.6
Uchida, M.7
Nagamitsu, T.8
Omura, S.9
Ikeda, H.10
Nihira, T.11
-
22
-
-
44949176042
-
Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol
-
1:CAS:528:DC%2BD1cXmvFOltL0%3D 18492804 10.1073/pnas.0802312105 2387273
-
Komatsu M, Tsuda M, Omura S, Oikawa H, Ikeda H (2008) Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol. Proc Natl Acad Sci U S A 105:7422-7427
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 7422-7427
-
-
Komatsu, M.1
Tsuda, M.2
Omura, S.3
Oikawa, H.4
Ikeda, H.5
-
23
-
-
77249153701
-
Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism
-
1:CAS:528:DC%2BC3cXit1aksbk%3D 20133795 10.1073/pnas.0914833107 2823899
-
Komatsu M, Uchiyama T, Omura S, Cane DE, Ikeda H (2010) Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism. Proc Natl Acad Sci U S A 107:2646-2651
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 2646-2651
-
-
Komatsu, M.1
Uchiyama, T.2
Omura, S.3
Cane, D.E.4
Ikeda, H.5
-
24
-
-
84872287714
-
Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolites
-
1:CAS:528:DC%2BC3sXmvVGgtg%3D%3D 10.1021/sb3001003
-
Komatsu M, Komatsu K, Koiwai H, Yamada Y, Kozone I, Izumikawa M, Hashimoto J, Takagi M, Omura S, Shin-ya K, Cane DE, Ikeda H (2013) Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolites. ACS Syn Biol 2:384-396
-
(2013)
ACS Syn Biol
, vol.2
, pp. 384-396
-
-
Komatsu, M.1
Komatsu, K.2
Koiwai, H.3
Yamada, Y.4
Kozone, I.5
Izumikawa, M.6
Hashimoto, J.7
Takagi, M.8
Omura, S.9
Shin-Ya, K.10
Cane, D.E.11
Ikeda, H.12
-
25
-
-
0036151758
-
Osmotically regulated synthesis of the compatible solute ectoine in Bacillus pasteurii and related Bacillus spp
-
1:CAS:528:DC%2BD38XhtV2ns7c%3D 10.1128/AEM.68.2.772-783.2002
-
Kuhlmann AU, Bremer E (2002) Osmotically regulated synthesis of the compatible solute ectoine in Bacillus pasteurii and related Bacillus spp. Appl Env Microbiol 68:772-783
-
(2002)
Appl Env Microbiol
, vol.68
, pp. 772-783
-
-
Kuhlmann, A.U.1
Bremer, E.2
-
26
-
-
0042672547
-
Cytochrome P450 complement of the avermectin-producer Streptomyces avermitilis and comparison to that of Streptomyces coelicolor A3(2)
-
1:CAS:528:DC%2BD3sXlvVCrs7k%3D 12893267 10.1016/S0006-291X(03)01231-2
-
Lamb DC, Ikeda Nelson DR, Ishikawa J, Skaug T, Jackson C, Omura S, Waterman MR, Kelly SL (2003) Cytochrome P450 complement of the avermectin-producer Streptomyces avermitilis and comparison to that of Streptomyces coelicolor A3(2). Biochem Biophys Res Commun 307:610-619
-
(2003)
Biochem Biophys Res Commun
, vol.307
, pp. 610-619
-
-
Lamb, D.C.1
Ikeda, N.D.2
Ishikawa, J.3
Skaug, T.4
Jackson, C.5
Omura, S.6
Waterman, M.R.7
Kelly, S.L.8
-
27
-
-
27544477567
-
Discovery of a new peptide natural product by Streptomyces coelicolor genome mining
-
1:CAS:528:DC%2BD2MXhtVamtrfM 16408055 10.1038/nchembio731
-
Lautru S, Deeth RJ, Bailey LM, Challis GL (2005) Discovery of a new peptide natural product by Streptomyces coelicolor genome mining. Nat Chem Biol 1:265-269
-
(2005)
Nat Chem Biol
, vol.1
, pp. 265-269
-
-
Lautru, S.1
Deeth, R.J.2
Bailey, L.M.3
Challis, G.L.4
-
28
-
-
69949157277
-
Biosynthesis of sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor. Mechanism and stereochemistry of the enzymatic formation of epi-isozizaene
-
1:CAS:528:DC%2BD1MXkvVGgtL0%3D 19385616 10.1021/ja901313v 2690639
-
Lin X, Cane DE (2009) Biosynthesis of sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor. Mechanism and stereochemistry of the enzymatic formation of epi-isozizaene. J Am Chem Soc 131:6332-6333
-
(2009)
J Am Chem Soc
, vol.131
, pp. 6332-6333
-
-
Lin, X.1
Cane, D.E.2
-
29
-
-
0030922377
-
Characterization of genes for the biosynthesis of the compatible solute ectoine from Marinococcus halophilus and osmoregulated expression in Escherichia coli
-
1:CAS:528:DyaK2sXjtVWqsLw%3D 9141677 10.1099/00221287-143-4-1141
-
Louis P, Galinski EA (1997) Characterization of genes for the biosynthesis of the compatible solute ectoine from Marinococcus halophilus and osmoregulated expression in Escherichia coli. Microbiology 143:1141-1149
-
(1997)
Microbiology
, vol.143
, pp. 1141-1149
-
-
Louis, P.1
Galinski, E.A.2
-
30
-
-
0030031726
-
Induction of synthesis of tetrahydropyrimidine derivatives in Streptomyces strains and their effect on Escherichia coli in response to osmotic and heat stress
-
1:CAS:528:DyaK28Xjs1WgtQ%3D%3D
-
Malin G, Lapidot A (1996) Induction of synthesis of tetrahydropyrimidine derivatives in Streptomyces strains and their effect on Escherichia coli in response to osmotic and heat stress. J Bactriol 178:385-395
-
(1996)
J Bactriol
, vol.178
, pp. 385-395
-
-
Malin, G.1
Lapidot, A.2
-
31
-
-
13944259584
-
Genetically modified bacterial strains and novel bacterial artificial chromosome shuttle vectors for constructing environmental libraries and detecting heterologous natural products in multiple expression hosts
-
1:CAS:528:DC%2BD2cXjtlOhs7c%3D 15066844 10.1128/AEM.70.4.2452-2463.2004 383137
-
Martinez A, Kolvek SJ, Yip CLT, Hopke J, Brown KA, MacNeil IA, Osburne MS (2004) Genetically modified bacterial strains and novel bacterial artificial chromosome shuttle vectors for constructing environmental libraries and detecting heterologous natural products in multiple expression hosts. Appl Environ Microbiol 70:2452-2463
-
(2004)
Appl Environ Microbiol
, vol.70
, pp. 2452-2463
-
-
Martinez, A.1
Kolvek, S.J.2
Yip, C.L.T.3
Hopke, J.4
Brown, K.A.5
Macneil, I.A.6
Osburne, M.S.7
-
32
-
-
77958475358
-
The sequence of a 1.8-Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways
-
20624727 10.1093/gbe/evq013 2997539
-
Medema MH, Trefzer A, Kovalchuk A, Berg M, Müller U, Heijne W, Wu L, Alam MT, Ronning CM, Nierman WC, Bovenberg RAL, Breitling R, Takano E (2010) The sequence of a 1.8-Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways. Genome Biol Evol 2:212-224
-
(2010)
Genome Biol Evol
, vol.2
, pp. 212-224
-
-
Medema, M.H.1
Trefzer, A.2
Kovalchuk, A.3
Berg, M.4
Müller, U.5
Heijne, W.6
Wu, L.7
Alam, M.T.8
Ronning, C.M.9
Nierman, W.C.10
Bovenberg, R.A.L.11
Breitling, R.12
Takano, E.13
-
33
-
-
70350722394
-
Genomic basis for natural product biosynthetic diversity in the actinomycetes
-
10.1039/b817069j
-
Nett M, Ikeda H, Moore BS (2009) Genomic basis for natural product biosynthetic diversity in the actinomycetes. Nat Prod Rep 26:1326-1384
-
(2009)
Nat Prod Rep
, vol.26
, pp. 1326-1384
-
-
Nett, M.1
Ikeda, H.2
Moore, B.S.3
-
34
-
-
44349169524
-
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350
-
1:CAS:528:DC%2BD1cXmsVOmsbg%3D 18375553 10.1128/JB.00204-08 2395044
-
Ohnishi Y, Ishikawa J, Hara H, Suzuki H, Ikenoya M, Ikeda H, Yamashita A, Hattori M, Horinouchi S (2008) Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350. J Bacteriol 190:4050-4060
-
(2008)
J Bacteriol
, vol.190
, pp. 4050-4060
-
-
Ohnishi, Y.1
Ishikawa, J.2
Hara, H.3
Suzuki, H.4
Ikenoya, M.5
Ikeda, H.6
Yamashita, A.7
Hattori, M.8
Horinouchi, S.9
-
35
-
-
0035834039
-
Genome sequence of an industrial microorganism Streptomyces avermitilis: Deducing the ability of producing secondary metabolites
-
1:CAS:528:DC%2BD3MXns1Cjtrk%3D 11572948 10.1073/pnas.211433198 59794
-
Omura S, Ikeda H, Ishikawa J, Hanamoto A, Takahashi C, Shinose M, Takahashi Y, Horikawa H, Nakazawa H, Osonoe T, Kikuchi H, Shiba T, Sakaki Y, Hattori M (2001) Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites. Proc Natl Acad Sci U S A 98:12215-12220
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 12215-12220
-
-
Omura, S.1
Ikeda, H.2
Ishikawa, J.3
Hanamoto, A.4
Takahashi, C.5
Shinose, M.6
Takahashi, Y.7
Horikawa, H.8
Nakazawa, H.9
Osonoe, T.10
Kikuchi, H.11
Shiba, T.12
Sakaki, Y.13
Hattori, M.14
-
36
-
-
0036306047
-
Process and metabolic strategies for improved production of Escherichia coli-derived 6-deoxyerythronolide B
-
1:CAS:528:DC%2BD38Xlt1Sntro%3D 12089005 10.1128/AEM.68.7.3287-3292.2002 126764
-
Pfeifer B, Hu Z, Licari P, Khosla C (2002) Process and metabolic strategies for improved production of Escherichia coli-derived 6-deoxyerythronolide B. Appl Environ Microbiol 68:3287-3292
-
(2002)
Appl Environ Microbiol
, vol.68
, pp. 3287-3292
-
-
Pfeifer, B.1
Hu, Z.2
Licari, P.3
Khosla, C.4
-
37
-
-
79953265166
-
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes
-
1:CAS:528:DC%2BC3MXkvV2guro%3D 21463507 10.1186/1471-2164-12-175 3087709
-
Pullan ST, Chandra G, Bibb MJ, Merrick M (2011) Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes. BMC Genomics 12:175
-
(2011)
BMC Genomics
, vol.12
, pp. 175
-
-
Pullan, S.T.1
Chandra, G.2
Bibb, M.J.3
Merrick, M.4
-
38
-
-
33749534302
-
Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtlI, a cytochrome P450 of Streptomyces avermitilis
-
1:CAS:528:DC%2BD28Xps1aksLk%3D 17017767 10.1021/ja0639214 2533730
-
Quaderer R, Omura S, Ikeda H, Cane DE (2006) Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtlI, a cytochrome P450 of Streptomyces avermitilis. J Am Chem Soc 128:13036-13037
-
(2006)
J Am Chem Soc
, vol.128
, pp. 13036-13037
-
-
Quaderer, R.1
Omura, S.2
Ikeda, H.3
Cane, D.E.4
-
39
-
-
79952425620
-
Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone
-
1:CAS:528:DC%2BC3MXhs1aitrs%3D 21250661 10.1021/bi1019786 3051010
-
Seo MJ, Zhu D, Endo S, Ikeda H, Cane DE (2011) Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone. Biochemistry 50:1739-1754
-
(2011)
Biochemistry
, vol.50
, pp. 1739-1754
-
-
Seo, M.J.1
Zhu, D.2
Endo, S.3
Ikeda, H.4
Cane, D.E.5
-
40
-
-
0024308490
-
Method for selection of transposable DNA and characterization of a new insertion sequence, IS493, from Streptomyces lividans
-
1:CAS:528:DyaK3cXktFynur0%3D 2549001 210283
-
Solenberg PJ, Burgett SG (1989) Method for selection of transposable DNA and characterization of a new insertion sequence, IS493, from Streptomyces lividans. J Bacteriol 171:4807-4813
-
(1989)
J Bacteriol
, vol.171
, pp. 4807-4813
-
-
Solenberg, P.J.1
Burgett, S.G.2
-
41
-
-
79251633167
-
Pentalenic acid is a shunt metabolite in the biosynthesis of the pentalenolactone family of metabolites: Hydroxylation of 1-deoxypentalenic acid mediated by CYP105D7 (SAV-7469) of Streptomyces avermitilis
-
1:CAS:528:DC%2BC3MXhtFSiur4%3D 21081950 10.1038/ja.2010.135 3030646
-
Takamatsu S, Xu LH, Fushinobu S, Shoun H, Komastu M, Cane DE, Ikeda H (2011) Pentalenic acid is a shunt metabolite in the biosynthesis of the pentalenolactone family of metabolites: hydroxylation of 1-deoxypentalenic acid mediated by CYP105D7 (SAV-7469) of Streptomyces avermitilis. J. Antibiot 64:65-71
-
(2011)
J. Antibiot
, vol.64
, pp. 65-71
-
-
Takamatsu, S.1
Xu, L.H.2
Fushinobu, S.3
Shoun, H.4
Komastu, M.5
Cane, D.E.6
Ikeda, H.7
-
42
-
-
79251608086
-
Characterization of a silent sesquiterpenoid biosynthetic pathway in Streptomyces avermitilis controlling epi-isozizaene albaflavenone biosynthesis and isolation of a new oxidized epi-isozizaene metabolite
-
1:CAS:528:DC%2BC3MXjt1Wqurk%3D 21342464 10.1111/j.1751-7915.2010.00209.x 3711710
-
Takamatsu S, Lin X, Nara A, Komatsu M, Cane DE, Ikeda H (2011) Characterization of a silent sesquiterpenoid biosynthetic pathway in Streptomyces avermitilis controlling epi-isozizaene albaflavenone biosynthesis and isolation of a new oxidized epi-isozizaene metabolite. Microb Biotechnol 4:184-191
-
(2011)
Microb Biotechnol
, vol.4
, pp. 184-191
-
-
Takamatsu, S.1
Lin, X.2
Nara, A.3
Komatsu, M.4
Cane, D.E.5
Ikeda, H.6
-
43
-
-
0019216927
-
Milbemycins, a new family of macrolide antibiotics: Fermentation, isolation and physico-chemical properties
-
1:CAS:528:DyaL3cXmtlKrtr8%3D 7451362 10.7164/antibiotics.33.1120
-
Takiguchi Y, Mishima H, Okuda M, Terao M, Aoki A, Fukuda R (1980) Milbemycins, a new family of macrolide antibiotics: fermentation, isolation and physico-chemical properties. J Antibiot 33:1120-1127
-
(1980)
J Antibiot
, vol.33
, pp. 1120-1127
-
-
Takiguchi, Y.1
Mishima, H.2
Okuda, M.3
Terao, M.4
Aoki, A.5
Fukuda, R.6
-
44
-
-
33646591928
-
A gene cluster for biosynthesis of the sesquiterpenoid antibiotic pentalenolactone in Streptomyces avermitilis
-
1:CAS:528:DC%2BD28XjsFKitLY%3D 16681390 10.1021/bi060419n 2518623
-
Tetzlaff CN, You Z, Cane DE, Takamatsu S, Omura S, Ikeda H (2006) A gene cluster for biosynthesis of the sesquiterpenoid antibiotic pentalenolactone in Streptomyces avermitilis. Biochemistry 45:6179-6186
-
(2006)
Biochemistry
, vol.45
, pp. 6179-6186
-
-
Tetzlaff, C.N.1
You, Z.2
Cane, D.E.3
Takamatsu, S.4
Omura, S.5
Ikeda, H.6
-
45
-
-
84255195189
-
Total synthesis and absolute configuration of avenolide, extracelluar factor in Streptomyces avermitilis
-
1:CAS:528:DC%2BC3MXhs1Gks7bF 21989459 10.1038/ja.2011.90
-
Uchida M, Takamatsu S, Arima S, Miyamoto KT, Kitani S, Nihira T, Ikeda H, Nagamitsu T (2011) Total synthesis and absolute configuration of avenolide, extracelluar factor in Streptomyces avermitilis. J Antibiot 64:781-787
-
(2011)
J Antibiot
, vol.64
, pp. 781-787
-
-
Uchida, M.1
Takamatsu, S.2
Arima, S.3
Miyamoto, K.T.4
Kitani, S.5
Nihira, T.6
Ikeda, H.7
Nagamitsu, T.8
-
46
-
-
78649870448
-
Nocardamin production by Streptomyces avermitilis
-
1:CAS:528:DC%2BC3cXjvF2nsbY%3D 10.3209/saj.SAJ230203
-
Ueki M, Suzuki R, Takamatsu S, Takagi H, Uramoto M, Ikeda H, Osada H (2009) Nocardamin production by Streptomyces avermitilis. Actinomycetologica 23:34-39
-
(2009)
Actinomycetologica
, vol.23
, pp. 34-39
-
-
Ueki, M.1
Suzuki, R.2
Takamatsu, S.3
Takagi, H.4
Uramoto, M.5
Ikeda, H.6
Osada, H.7
-
47
-
-
77956529801
-
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis
-
1:CAS:528:DC%2BC3cXhtlegsbbI 20581206 10.1128/JB.00596-10 2937363
-
Wang XJ, Yan YJ, Zhang B, An J, Wang JJ, Tian J, Jiang L, Chen YH, Huang SX, Yin M, Zhang J, Gao AL, Liu CX, Zhu ZX, Xiang WS (2010) Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis. J Bacteriol 192:4526-4527
-
(2010)
J Bacteriol
, vol.192
, pp. 4526-4527
-
-
Wang, X.J.1
Yan, Y.J.2
Zhang, B.3
An, J.4
Wang, J.J.5
Tian, J.6
Jiang, L.7
Chen, Y.H.8
Huang, S.X.9
Yin, M.10
Zhang, J.11
Gao, A.L.12
Liu, C.X.13
Zhu, Z.X.14
Xiang, W.S.15
-
48
-
-
60849125093
-
Crystal structures of cytochrome P450 105P1 from Streptomyces avermitilis: Conformational flexibility and histidine-liganded state
-
1:CAS:528:DC%2BD1MXhvFCmtLg%3D 19074393 10.1128/JB.01276-08 2631996
-
Xu L, Fushinobu S, Ikeda H, Wakagi T, Shoun H (2009) Crystal structures of cytochrome P450 105P1 from Streptomyces avermitilis: conformational flexibility and histidine-liganded state. J Bacteriol 191:1211-1219
-
(2009)
J Bacteriol
, vol.191
, pp. 1211-1219
-
-
Xu, L.1
Fushinobu, S.2
Ikeda, H.3
Wakagi, T.4
Shoun, H.5
-
49
-
-
77952754570
-
Regio- and stereospecificity of filipin hydroxylation sites revealed by crystal structures of cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis
-
1:CAS:528:DC%2BC3cXmtlygtrY%3D 20375018 10.1074/jbc.M109.092460
-
Xu L, Fushinobu S, Takamatsu S, Wakagi T, Ikeda H, Shoun H (2010) Regio- and stereospecificity of filipin hydroxylation sites revealed by crystal structures of cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis. J Biol Chem 285:16844-16853
-
(2010)
J Biol Chem
, vol.285
, pp. 16844-16853
-
-
Xu, L.1
Fushinobu, S.2
Takamatsu, S.3
Wakagi, T.4
Ikeda, H.5
Shoun, H.6
-
50
-
-
33646720503
-
Pentalenolactone biosynthesis. Moleclar cloning and assignment of biochemical function to PtlH, a non-heme iron dioxygenase of Streptomyces avermitilis
-
1:CAS:528:DC%2BD28XjvFyiur4%3D 16704250 10.1021/ja061469i 2533727
-
You Z, Omura S, Ikeda H, Cane DE (2006) Pentalenolactone biosynthesis. Moleclar cloning and assignment of biochemical function to PtlH, a non-heme iron dioxygenase of Streptomyces avermitilis. J Am Chem Soc 128:6566-6567
-
(2006)
J Am Chem Soc
, vol.128
, pp. 6566-6567
-
-
You, Z.1
Omura, S.2
Ikeda, H.3
Cane, D.E.4
-
51
-
-
37549011812
-
Crystal structure of the non-heme iron dioxygenase PtlH in pentalenolactone biosynthesis
-
1:CAS:528:DC%2BD2sXhsVSgtrnN 17942405 10.1074/jbc.M706358200 3010413
-
You Z, Omura S, Ikeda H, Cane DE, Jogl G (2007) Crystal structure of the non-heme iron dioxygenase PtlH in pentalenolactone biosynthesis. J Biol Chem 282:36552-36560
-
(2007)
J Biol Chem
, vol.282
, pp. 36552-36560
-
-
You, Z.1
Omura, S.2
Ikeda, H.3
Cane, D.E.4
Jogl, G.5
-
52
-
-
79951833485
-
Genome mining in Streptomyces. Discovery of an unprecedented P450-catalyzed oxidative rearrangement that is the final step in the biosynthesis of pentalenolactone
-
1:CAS:528:DC%2BC3MXhsVOnsbk%3D 21284395 10.1021/ja111279h 3041837
-
Zhu D, Seo MJ, Ikeda H, Cane DE (2011) Genome mining in Streptomyces. Discovery of an unprecedented P450-catalyzed oxidative rearrangement that is the final step in the biosynthesis of pentalenolactone. J Am Chem Soc 133:2128-2131
-
(2011)
J Am Chem Soc
, vol.133
, pp. 2128-2131
-
-
Zhu, D.1
Seo, M.J.2
Ikeda, H.3
Cane, D.E.4
|