Regulation of death induction and chemosensitizing action of 3-bromopyruvate in myeloid leukemia cells: Energy depletion, oxidative stress, and protein kinase activity modulations

Journal of Pharmacology and Experimental Therapeutics

Volumn 348, Issue 2, 2014, Pages 324-335

  Calviño, Eva ^a   Estañ, María Cristina ^a   Sánchez Martín, Carlos ^a   Brea, Rocío ^a   De Blas, Elena ^a   Del Carmen Boyano Adánez, María ^b   Rial, Eduardo ^a   Aller, Patricio ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; ANTINEOPLASTIC AGENT; ARSENIC TRIOXIDE; BROMOPYRUVIC ACID; CURCUMIN; GLUTATHIONE; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE LKB1; PYRUVIC ACID; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CELL ENERGY; CHEMOSENSITIZATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EFFECT; ENERGY METABOLISM; ENZYME ACTIVATION; GLYCOLYSIS; HUMAN; HUMAN CELL; LEUKEMIA CELL; METABOLIC INHIBITION; MITOCHONDRIAL RESPIRATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 84893048809     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.113.206714     Document Type: Article

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