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Volumn 5, Issue 4, 2012, Pages 226-229

The scarlet letter of alkylation: A mini review of selective alkylating agents

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; NUCLEOPHILE; PRODRUG; PYRUVIC ACID DERIVATIVE; RRX 001; TH 302; UNCLASSIFIED DRUG;

EID: 84865460976     PISSN: None     EISSN: 19365233     Source Type: Journal    
DOI: 10.1593/tlo.12187     Document Type: Article
Times cited : (34)

References (13)
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  • 2
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    • Covalent modifiers: An orthogonal approach to drug design
    • Potashman MH and Duggan ME (2009). Covalent modifiers: an orthogonal approach to drug design. J Med Chem 52, 1231-1246.
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  • 4
    • 0011511768 scopus 로고    scopus 로고
    • Mechanisms of action of cancer chemotherapeutic agents: DNA-interactive alkylating agents and antitumour platinum-based drugs
    • Nature Publishing Group, London, UK
    • Siddik ZH (2002). Mechanisms of action of cancer chemotherapeutic agents: DNA-interactive alkylating agents and antitumour platinum-based drugs. In The Cancer Handbook. Nature Publishing Group, London, UK. pp. 1295-1313.
    • (2002) The Cancer Handbook , pp. 1295-1313
    • Siddik, Z.H.1
  • 5
    • 34248198488 scopus 로고    scopus 로고
    • Recent advances in heterolytic nucleofugal leaving groups
    • Lepore SD and Mondal D (2007). Recent advances in heterolytic nucleofugal leaving groups. Tetrahedron 63, 5103-5122.
    • (2007) Tetrahedron , vol.63 , pp. 5103-5122
    • Lepore, S.D.1    Mondal, D.2
  • 6
    • 0001727623 scopus 로고
    • The mechanism of action of alkylating agents
    • Warwick GP (1963). The mechanism of action of alkylating agents. Cancer Res 23, 1315-1333.
    • (1963) Cancer Res , vol.23 , pp. 1315-1333
    • Warwick, G.P.1
  • 9
    • 60249083822 scopus 로고    scopus 로고
    • Hexokinase-2 bound to mitochondria: Cancer's stygian link to the Warburg effect and a pivotal target for effective therapy
    • Mathupala SP, Ko YH, and Pedersen PL (2009). Hexokinase-2 bound to mitochondria: cancer's stygian link to the Warburg effect and a pivotal target for effective therapy. Semin Cancer Biol 19, 17-24.
    • (2009) Semin Cancer Biol , vol.19 , pp. 17-24
    • Mathupala, S.P.1    Ko, Y.H.2    Pedersen, P.L.3
  • 10
    • 0037099685 scopus 로고    scopus 로고
    • Novel therapy for liver cancer: Direct intraarterial injection of a potent inhibitor of ATP production
    • Geschwind JF, Ko YH, Torbenson MS, Magee C, and Pedersen PL (2002). Novel therapy for liver cancer: direct intraarterial injection of a potent inhibitor of ATP production. Cancer Res 62, 3909-3913.
    • (2002) Cancer Res , vol.62 , pp. 3909-3913
    • Geschwind, J.F.1    Ko, Y.H.2    Torbenson, M.S.3    Magee, C.4    Pedersen, P.L.5
  • 11
    • 33947726287 scopus 로고    scopus 로고
    • Intraarterial therapy with a new potent inhibitor of tumor metabolism (3-bromopyruvate): Identification of therapeutic dose and method of injection in an animal model of liver cancer
    • Vali M, Liapi E, Kowalski J, Hong K, Khwaja A, Torbenson MS, Georgiades C, and Geschwind JF (2007). Intraarterial therapy with a new potent inhibitor of tumor metabolism (3-bromopyruvate): identification of therapeutic dose and method of injection in an animal model of liver cancer. J Vasc Intery Radiol 18, 95-101.
    • (2007) J Vasc Intery Radiol , vol.18 , pp. 95-101
    • Vali, M.1    Liapi, E.2    Kowalski, J.3    Hong, K.4    Khwaja, A.5    Torbenson, M.S.6    Georgiades, C.7    Geschwind, J.F.8
  • 13
    • 79960313911 scopus 로고    scopus 로고
    • Six degrees of separation: The oxygen effect in the development of radiosensitizers
    • Oronsky BT, Knox SJ, and Scicinski J (2011). Six degrees of separation: the oxygen effect in the development of radiosensitizers. Transl Oncol 4, 189-198.
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    • Oronsky, B.T.1    Knox, S.J.2    Scicinski, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.