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Volumn 33, Issue 1, 2013, Pages 13-20

Anticancer efficacy of the metabolic blocker 3-bromopyruvate: Specific molecular targeting

Author keywords

3 Bromopyruvate; GAPDH; Glucose metabolism; Glycolysis; HCC; Locoregional therapy; Molecular targeting; Review

Indexed keywords

ALKYLATING AGENT; BROMOPYRUVIC ACID; DAUNORUBICIN; DEOXYGLUCOSE; FLUOROURACIL; GLYCERALDEHYDE 3 PHOSPHATE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; LACTATE DEHYDROGENASE; MITOXANTRONE; PYRUVIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

EID: 84873027161     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (68)

References (37)
  • 1
    • 79954970234 scopus 로고    scopus 로고
    • Usefulness of 18F-FDG-PET, combined FDGPET/ CT and EUS in diagnosing primary pancreatic carcinoma: A meta-analysis
    • Tang S, Huang G, Liu J, Liu T, Treven L, Song S, Zhang C, Pan L and Zhang T: Usefulness of 18F-FDG-PET, combined FDGPET/ CT and EUS in diagnosing primary pancreatic carcinoma: A meta-analysis. Eur J Radiol 78(1): 142-150, 2011.
    • (2011) Eur J Radiol , vol.78 , Issue.1 , pp. 142-150
    • Tang, S.1    Huang, G.2    Liu, J.3    Liu, T.4    Treven, L.5    Song, S.6    Zhang, C.7    Pan, L.8    Zhang, T.9
  • 3
    • 81855177061 scopus 로고    scopus 로고
    • Targeting glucose metabolism: An emerging concept for anticancer therapy
    • Madhok BM, Yeluri S, Perry SL, Hughes TA and Jayne DG: Targeting glucose metabolism: An emerging concept for anticancer therapy. Am J Clin Oncol 34(6): 628-635, 2011.
    • (2011) Am J Clin Oncol , vol.34 , Issue.6 , pp. 628-635
    • Madhok, B.M.1    Yeluri, S.2    Perry, S.L.3    Hughes, T.A.4    Jayne, D.G.5
  • 4
    • 84860512005 scopus 로고    scopus 로고
    • Links between metabolism and cancer
    • Dang CV: Links between metabolism and cancer. Genes Dev 26(9):877-890, 2012.
    • (2012) Genes Dev , vol.26 , Issue.9 , pp. 877-890
    • Dang, C.V.1
  • 5
    • 69849087571 scopus 로고    scopus 로고
    • Targeting glucose metabolism with 2-deoxy-D-glucose for improving cancer therapy
    • Dwarakanath B and Jain V: Targeting glucose metabolism with 2-deoxy-D-glucose for improving cancer therapy. Future Oncol 5(5): 581-585, 2009.
    • (2009) Future Oncol , vol.5 , Issue.5 , pp. 581-585
    • Dwarakanath, B.1    Jain, V.2
  • 6
    • 33746879141 scopus 로고    scopus 로고
    • Glycolysis inhibition for anticancer treatment
    • Pelicano H, Martin DS, Xu RH and Huang P: Glycolysis inhibition for anticancer treatment. Oncogene 25(34): 4633-4646, 2006.
    • (2006) Oncogene , vol.25 , Issue.34 , pp. 4633-4646
    • Pelicano, H.1    Martin, D.S.2    Xu, R.H.3    Huang, P.4
  • 7
    • 33744783432 scopus 로고    scopus 로고
    • Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
    • Fantin VR, St-Pierre J and Leder P: Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. Cancer Cell 9(6): 425-434, 2006.
    • (2006) Cancer Cell , vol.9 , Issue.6 , pp. 425-434
    • Fantin, V.R.1    St-Pierre, J.2    Leder, P.3
  • 9
    • 84865746708 scopus 로고    scopus 로고
    • Glutamine deprivation enhances antitumor activity of 3-bromopyruvate through the stabilization of monocarboxylate transporter-1
    • Cardaci S, Rizza S, Filomeni G, Bernardini R, Bertocchi F, Mattei M, Paci M, Rotilio G and Ciriolo MR: Glutamine deprivation enhances antitumor activity of 3-bromopyruvate through the stabilization of monocarboxylate transporter-1. Cancer Res 72(17): 4526-4536, 2012.
    • (2012) Cancer Res , vol.72 , Issue.17 , pp. 4526-4536
    • Cardaci, S.1    Rizza, S.2    Filomeni, G.3    Bernardini, R.4    Bertocchi, F.5    Mattei, M.6    Paci, M.7    Rotilio, G.8    Ciriolo, M.R.9
  • 10
    • 84856860890 scopus 로고    scopus 로고
    • Targeting glucose metabolism for cancer therapy
    • Hamanaka RB and Chandel NS: Targeting glucose metabolism for cancer therapy. J Exp Med 209(2): 211-215, 2012.
    • (2012) J Exp Med , vol.209 , Issue.2 , pp. 211-215
    • Hamanaka, R.B.1    Chandel, N.S.2
  • 11
    • 0035829074 scopus 로고    scopus 로고
    • Glucose catabolism in the rabbit VX2 tumor model for liver cancer: Characterization and targeting hexokinase
    • Ko YH, Pedersen PL and Geschwind JF: Glucose catabolism in the rabbit VX2 tumor model for liver cancer: Characterization and targeting hexokinase. Cancer Lett 173(1): 83-91, 2001.
    • (2001) Cancer Lett , vol.173 , Issue.1 , pp. 83-91
    • Ko, Y.H.1    Pedersen, P.L.2    Geschwind, J.F.3
  • 12
    • 0037099685 scopus 로고    scopus 로고
    • Novel therapy for liver cancer: Direct intra-arterial injection of a potent inhibitor of ATP production
    • Geschwind JF, Ko YH, Torbenson MS, Magee C and Pedersen PL: Novel therapy for liver cancer: Direct intra-arterial injection of a potent inhibitor of ATP production. Cancer Res 62(14): 3909-3913, 2002.
    • (2002) Cancer Res , vol.62 , Issue.14 , pp. 3909-3913
    • Geschwind, J.F.1    Ko, Y.H.2    Torbenson, M.S.3    Magee, C.4    Pedersen, P.L.5
  • 16
    • 84862777922 scopus 로고    scopus 로고
    • Overexpression of GAPDH in human colorectal carcinoma as a preferred target of 3-bromopyruvate propyl ester
    • Tang Z, Yuan S, Hu Y, Zhang H, Wu W, Zeng Z, Yang J, Yun J, Xu R and Huang P: Overexpression of GAPDH in human colorectal carcinoma as a preferred target of 3-bromopyruvate propyl ester. J Bioenerg Biomembr 44(1): 117-125, 2012.
    • (2012) J Bioenerg Biomembr , vol.44 , Issue.1 , pp. 117-125
    • Tang, Z.1    Yuan, S.2    Hu, Y.3    Zhang, H.4    Wu, W.5    Zeng, Z.6    Yang, J.7    Yun, J.8    Xu, R.9    Huang, P.10
  • 17
    • 43649097186 scopus 로고    scopus 로고
    • 3-Bromopyruvate as inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs
    • Ihrlund LS, Hernlund E, Khan O and Shoshan MC: 3-Bromopyruvate as inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs. Mol Oncol 2(1): 94-101, 2008.
    • (2008) Mol Oncol , vol.2 , Issue.1 , pp. 94-101
    • Ihrlund, L.S.1    Hernlund, E.2    Khan, O.3    Shoshan, M.C.4
  • 19
    • 84858716352 scopus 로고    scopus 로고
    • Human hepatocellular carcinoma in a mouse model: Assessment of tumor response to percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists
    • Ganapathy-Kanniappan S, Kunjithapatham R, Torbenson MS, Rao PP, Carson KA, Buijs M, Vali M and Geschwind JF: Human hepatocellular carcinoma in a mouse model: Assessment of tumor response to percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists. Radiology 262(3): 834-845, 2012.
    • (2012) Radiology , vol.262 , Issue.3 , pp. 834-845
    • Ganapathy-Kanniappan, S.1    Kunjithapatham, R.2    Torbenson, M.S.3    Rao, P.P.4    Carson, K.A.5    Buijs, M.6    Vali, M.7    Geschwind, J.F.8
  • 20
    • 67849086442 scopus 로고    scopus 로고
    • Human serum albumin interaction with oxaliplatin studied by capillary isoelectric focusing with the whole column imaging detection and spectroscopic method
    • Lemma T and Pawliszyn J: Human serum albumin interaction with oxaliplatin studied by capillary isoelectric focusing with the whole column imaging detection and spectroscopic method. J Pharm Biomed Anal 50(4): 570-575, 2009.
    • (2009) J Pharm Biomed Anal , vol.50 , Issue.4 , pp. 570-575
    • Lemma, T.1    Pawliszyn, J.2
  • 21
    • 77649227455 scopus 로고    scopus 로고
    • Reactivity of anticancer metallodrugs with serum proteins: New insights from size exclusion chromatography-ICPMS and ESI-MS
    • Groessl M, Terenghi M, Casini A, Elviri L, Lobinski R and Dyson PJ: Reactivity of anticancer metallodrugs with serum proteins: New insights from size exclusion chromatography-ICPMS and ESI-MS. J Anal At Spectrom 25(3): 305-313, 2010.
    • (2010) J Anal at Spectrom , vol.25 , Issue.3 , pp. 305-313
    • Groessl, M.1    Terenghi, M.2    Casini, A.3    Elviri, L.4    Lobinski, R.5    Dyson, P.J.6
  • 22
    • 0032563825 scopus 로고    scopus 로고
    • Doxorubicin-induced cardiomyopathy
    • Singal PK and Iliskovic N: Doxorubicin-induced cardiomyopathy. N Engl J Med 339(13): 900-905, 1998.
    • (1998) N Engl J Med , vol.339 , Issue.13 , pp. 900-905
    • Singal, P.K.1    Iliskovic, N.2
  • 27
    • 70350101307 scopus 로고    scopus 로고
    • Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3-bromopyruvate
    • Thangaraju M, Karunakaran SK, Itagaki S, Gopal E, Elangovan S, Prasad PD and Ganapathy V: Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3-bromopyruvate. Cancer 115(20): 4655-4666, 2009.
    • (2009) Cancer , vol.115 , Issue.20 , pp. 4655-4666
    • Thangaraju, M.1    Karunakaran, S.K.2    Itagaki, S.3    Gopal, E.4    Elangovan, S.5    Prasad, P.D.6    Ganapathy, V.7
  • 29
  • 30
    • 51849088295 scopus 로고    scopus 로고
    • Non-invasive MRI tumor imaging and synergistic anticancer effect of HSP90 inhibitor and glycolysis inhibitor in RIP1-Tag2 transgenic pancreatic tumor model
    • Cao X, Jia G, Zhang T, Yang M, Wang B, Wassenaar PA, Cheng H, Knopp MV and Sun D: Non-invasive MRI tumor imaging and synergistic anticancer effect of HSP90 inhibitor and glycolysis inhibitor in RIP1-Tag2 transgenic pancreatic tumor model. Cancer Chemother Pharmacol 62(6): 985-994, 2008.
    • (2008) Cancer Chemother Pharmacol , vol.62 , Issue.6 , pp. 985-994
    • Cao, X.1    Jia, G.2    Zhang, T.3    Yang, M.4    Wang, B.5    Wassenaar, P.A.6    Cheng, H.7    Knopp, M.V.8    Sun, D.9
  • 31
    • 79960263592 scopus 로고    scopus 로고
    • Metabolic oxidative stress elicited by the copper (II) complex [Cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of the AMP-activated protein kinase/p38MAPK/p53 signaling axis: Evidence for a combined use with 3-bromopyruvate in neuroblastoma treatment
    • Filomeni G, Cardaci S, Da Costa Ferreira AM, Rotilio G and Ciriolo MR: Metabolic oxidative stress elicited by the copper (II) complex [Cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of the AMP-activated protein kinase/p38MAPK/p53 signaling axis: Evidence for a combined use with 3-bromopyruvate in neuroblastoma treatment. Biochem J 437(3): 443-453, 2011.
    • (2011) Biochem J , vol.437 , Issue.3 , pp. 443-453
    • Filomeni, G.1    Cardaci, S.2    Da Costa Ferreira, A.M.3    Rotilio, G.4    Ciriolo, M.R.5
  • 32
    • 79960056596 scopus 로고    scopus 로고
    • Inhibition of hypoxia-inducible carbonic anhydrase-IX enhances hexokinase II inhibitor-induced hepatocellular carcinoma cell apoptosis
    • Yu SJ, Yoon JH, Lee JH, Myung SJ, Jang ES, Kwak MS, Cho EJ, Jang JJ, Kim YJ and Lee HS: Inhibition of hypoxia-inducible carbonic anhydrase-IX enhances hexokinase II inhibitor-induced hepatocellular carcinoma cell apoptosis. Acta Pharmacol Sin 32(7): 912-920, 2011.
    • (2011) Acta Pharmacol Sin , vol.32 , Issue.7 , pp. 912-920
    • Yu, S.J.1    Yoon, J.H.2    Lee, J.H.3    Myung, S.J.4    Jang, E.S.5    Kwak, M.S.6    Cho, E.J.7    Jang, J.J.8    Kim, Y.J.9    Lee, H.S.10
  • 34
    • 84862777172 scopus 로고    scopus 로고
    • Enhancement of hexokinase II inhibitor-induced apoptosis in hepatocellular carcinoma cells via augmenting ER stress and antiangiogenesis by protein disulfide isomerase inhibition
    • Yu SJ, Yoon JH, Yang JI, Cho EJ, Kwak MS, Jang ES, Lee JH, Kim YJ, Lee HS and Kim CY: Enhancement of hexokinase II inhibitor-induced apoptosis in hepatocellular carcinoma cells via augmenting ER stress and antiangiogenesis by protein disulfide isomerase inhibition. J Bioenerg Biomembr 44(1): 101-115, 2012.
    • (2012) J Bioenerg Biomembr , vol.44 , Issue.1 , pp. 101-115
    • Yu, S.J.1    Yoon, J.H.2    Yang, J.I.3    Cho, E.J.4    Kwak, M.S.5    Jang, E.S.6    Lee, J.H.7    Kim, Y.J.8    Lee, H.S.9    Kim, C.Y.10
  • 35
    • 84870667447 scopus 로고    scopus 로고
    • Repeated cisplatin treatment can lead to a multiresistant tumor cell population with stem cell features and sensitivity to 3-bromopyruvate
    • Wintzell M, Lofstedt L, Johansson J, Pedersen AB, Fuxe J and Shoshan M: Repeated cisplatin treatment can lead to a multiresistant tumor cell population with stem cell features and sensitivity to 3-bromopyruvate Cancer Biol Ther 13(14): 2012.
    • (2012) Cancer Biol Ther , vol.13 , Issue.14
    • Wintzell, M.1    Lofstedt, L.2    Johansson, J.3    Pedersen, A.B.4    Fuxe, J.5    Shoshan, M.6


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