Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate

Biochemical Journal

Volumn 417, Issue 3, 2009, Pages 717-726

  Periera da Silva, Ana Paula ^a   El Bacha, Tatiana ^a   Kyaw, Nattascha ^a   dos Santosa, Reinaldo Sousa ^a   da Silva, Wagner Seixas ^a   Almeida, Fabio C ^a   da Poian, Andrea T ^a   Galina, Antonio ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

3 bromopyruvate; Glycolysis; Hepatocellular carcinoma; HepG2 cell; Mitochondrion; Oxygen consumption; Tumour cell

Indexed keywords

3-BROMOPYRUVATE; GLYCOLYSIS; HEPATOCELLULAR CARCINOMA; HEPG2 CELL; OXYGEN CONSUMPTION; TUMOUR CELL;

CELL DEATH; ENZYMES; GLUCOSE; OXYGEN; PATHOLOGY; PHOSPHORYLATION; PLANTS (BOTANY); TUMORS;

CELL MEMBRANES;

6 PHOSPHOFRUCTOKINASE; ANTIMYCIN A1; BROMOPYRUVIC ACID; GLUCOSE; GLUCOSE 6 PHOSPHATE ISOMERASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; LACTIC ACID; MALIC ACID; MITOCHONDRIAL ENZYME; MITOCHONDRIAL HEXOKINASE II; OLIGOMYCIN; PHOSPHOGLYCERATE KINASE; PYRUVATE KINASE; PYRUVIC ACID DERIVATIVE; SUCCINATE DEHYDROGENASE; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; ENZYME INHIBITOR;

ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL DEATH; CELL PERMEABILIZATION; CELL STRAIN HEPG2; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENERGY METABOLISM; ENERGY YIELD; ENZYME INHIBITION; GLYCOLYSIS; HUMAN; HUMAN CELL; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; TIME; DRUG ANTAGONISM; DRUG EFFECT; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; MITOCHONDRION;

ADENOSINE TRIPHOSPHATE; CARCINOMA, HEPATOCELLULAR; ENERGY METABOLISM; ENZYME INHIBITORS; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; GLYCOLYSIS; HUMANS; LACTIC ACID; LIVER NEOPLASMS; MITOCHONDRIA; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PYRUVATES; SUCCINATE DEHYDROGENASE;

EID: 59849092584     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20080805     Document Type: Article

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