메뉴 건너뛰기




Volumn , Issue , 2006, Pages 161-186

Physiological regulation of bone metabolism and estrogen agonism

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84892882831     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/3-540-34742-9_7     Document Type: Chapter
Times cited : (3)

References (143)
  • 2
    • 0028362416 scopus 로고
    • Osteonal and hemi-osteonal remodeling: The spatial and temporal framework for signal traffic in adult human bone
    • Parfitt AM (1994) Osteonal and hemi-osteonal remodeling: the spatial and temporal framework for signal traffic in adult human bone. J Cell Biochem 55:273-286
    • (1994) J Cell Biochem , vol.55 , pp. 273-286
    • Parfitt, A.M.1
  • 3
    • 0034455103 scopus 로고    scopus 로고
    • Birth and death of bone cells: Basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
    • Manolagas SC (2000) Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocr Rev 21:115-137
    • (2000) Endocr Rev , vol.21 , pp. 115-137
    • Manolagas, S.C.1
  • 4
    • 0019847761 scopus 로고
    • Role of osteoblast in hormonal control of bone resorption - A hypothesis
    • Rodan GA, Martin TJ (1981) Role of osteoblast in hormonal control of bone resorption - a hypothesis. Calcif Tissue Int 33:349-351
    • (1981) Calcif Tissue Int , vol.33 , pp. 349-351
    • Rodan, G.A.1    Martin, T.J.2
  • 8
    • 0028925088 scopus 로고
    • Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis
    • Manolagas SC, Jilka RL (1995) Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis. N Engl J Med 332:305-311
    • (1995) N Engl J Med , vol.332 , pp. 305-311
    • Manolagas, S.C.1    Jilka, R.L.2
  • 9
    • 0033981552 scopus 로고    scopus 로고
    • Loss of osteocyte integrity in association with microdamage and bone remodeling after fatigue in vivo
    • Verborgt O, Gibson GJ, Schaffer MB (2000) Loss of osteocyte integrity in association with microdamage and bone remodeling after fatigue in vivo. J Bone Miner Res 15:60-67
    • (2000) J Bone Miner Res , vol.15 , pp. 60-67
    • Verborgt, O.1    Gibson, G.J.2    Schaffer, M.B.3
  • 10
    • 0042844489 scopus 로고    scopus 로고
    • Biology of the basic multicellular unit and the pathophysiology of osteoporosis
    • Jilka RL (2003) Biology of the basic multicellular unit and the pathophysiology of osteoporosis. Med Pediatr Oncol 41:182-185
    • (2003) Med Pediatr Oncol , vol.41 , pp. 182-185
    • Jilka, R.L.1
  • 11
    • 0034166650 scopus 로고    scopus 로고
    • The mechanism of coupling: A role for the vasculature
    • Parfitt AM (2000) The mechanism of coupling: a role for the vasculature. Bone 26:319-323
    • (2000) Bone , vol.26 , pp. 319-323
    • Parfitt, A.M.1
  • 12
    • 0034873321 scopus 로고    scopus 로고
    • The bone remodeling compartment: A circulatory function for bone lining cells
    • Parfitt AM (2001) The bone remodeling compartment: a circulatory function for bone lining cells. J Bone Miner Res 16:1583-1585
    • (2001) J Bone Miner Res , vol.16 , pp. 1583-1585
    • Parfitt, A.M.1
  • 14
    • 0002203349 scopus 로고    scopus 로고
    • The stem cell of the osteoblast
    • Bilezikian JP, Raisz LG, Rodan GA eds, Academic, San Diego
    • Triffitt JT (1996) The stem cell of the osteoblast. In: Bilezikian JP, Raisz LG, Rodan GA (eds) Principles of bone biology. Academic, San Diego, pp 39-50
    • (1996) Principles of Bone Biology , pp. 39-50
    • Triffitt, J.T.1
  • 15
    • 0030690556 scopus 로고    scopus 로고
    • The missing bone
    • Rodan GA, Harada SI (1997) The missing bone. Cell 89:677-680
    • (1997) Cell , vol.89 , pp. 677-680
    • Rodan, G.A.1    Harada, S.I.2
  • 16
    • 0242668869 scopus 로고    scopus 로고
    • Bone morphogenetic proteins, their antagonist, and the skeleton
    • Canalis E, Economides AN, Gazzerro E (2003) Bone morphogenetic proteins, their antagonist, and the skeleton. Endocr Rev 24:218-235
    • (2003) Endocr Rev , vol.24 , pp. 218-235
    • Canalis, E.1    Economides, A.N.2    Gazzerro, E.3
  • 19
    • 0034460993 scopus 로고    scopus 로고
    • Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12
    • Lee KS, Kim HJ, Li QL, Chi XZ, Ueta C, Komori T, Wozney JM, Kim EG, Choi JY, Ryoo HM, Bae SC (2000) Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12. Mol Cell Biol 20:8783-8792
    • (2000) Mol Cell Biol , vol.20 , pp. 8783-8792
    • Lee, K.S.1    Kim, H.J.2    Li, Q.L.3    Chi, X.Z.4    Ueta, C.5    Komori, T.6    Wozney, J.M.7    Kim, E.G.8    Choi, J.Y.9    Ryoo, H.M.10    Bae, S.C.11
  • 20
    • 0036399170 scopus 로고    scopus 로고
    • Extracellular regulation of BMP signaling in vertebrates: A cocktail of modulators
    • Balemans W, Van Hul W (2002) Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators. Dev Biol 250:231-250
    • (2002) Dev Biol , vol.250 , pp. 231-250
    • Balemans, W.1    Van Hul, W.2
  • 21
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
    • Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G (1997) Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 89:747-754
    • (1997) Cell , vol.89 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3    Ridall, A.L.4    Karsenty, G.5
  • 22
    • 0031671856 scopus 로고    scopus 로고
    • Genetic control of cell differentiation in the skeleton
    • Ducy P, Karsenty G (1998) Genetic control of cell differentiation in the skeleton. Curr Opin Cell Biol 10:614-619
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 614-619
    • Ducy, P.1    Karsenty, G.2
  • 24
    • 0037673933 scopus 로고    scopus 로고
    • Control of osteoblast function and regulation of bone mass
    • Harada S, Rodan GA (2003) Control of osteoblast function and regulation of bone mass. Nature 423:349-355
    • (2003) Nature , vol.423 , pp. 349-355
    • Harada, S.1    Rodan, G.A.2
  • 25
    • 0034285013 scopus 로고    scopus 로고
    • The osteoblast: A sophisticated fibroblast under central surveillance
    • Ducy P, Schinke T, Karsenty G (2000) The osteoblast: a sophisticated fibroblast under central surveillance. Science 289:1501-1504
    • (2000) Science , vol.289 , pp. 1501-1504
    • Ducy, P.1    Schinke, T.2    Karsenty, G.3
  • 28
    • 0032192369 scopus 로고    scopus 로고
    • How the osteoclast degrades bone
    • Blair HC (1998) How the osteoclast degrades bone. Bioessays 20:837-846
    • (1998) Bioessays , vol.20 , pp. 837-846
    • Blair, H.C.1
  • 29
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle WJ, Simonet WS, Lacey DL (2003) Osteoclast differentiation and activation. Nature 423:337-342
    • (2003) Nature , vol.423 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 30
    • 0001690310 scopus 로고
    • Carbonic anhydrase II deficiency identified as the primary defect in the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification
    • Sly WS, Hewett-Emmett D, Whyte MP, Yu YS, Tashian RE (1983) Carbonic anhydrase II deficiency identified as the primary defect in the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification. Proc Natl Acad Sci USA 80:2752-2756
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 2752-2756
    • Sly, W.S.1    Hewett-Emmett, D.2    Whyte, M.P.3    Yu, Y.S.4    Tashian, R.E.5
  • 32
    • 0026551143 scopus 로고
    • Rat osteoclasts adhere to a wide range of RGD (Arg-Gly-Asp) peptide-containing proteins, including the bone sialoproteins and fibronectin, via a beta 3 integrin
    • Helfrich MH, Nesbitt SA, Dorey EL, Horton MA (1992) Rat osteoclasts adhere to a wide range of RGD (Arg-Gly-Asp) peptide-containing proteins, including the bone sialoproteins and fibronectin, via a beta 3 integrin. J Bone Miner Res 7:335-343
    • (1992) J Bone Miner Res , vol.7 , pp. 335-343
    • Helfrich, M.H.1    Nesbitt, S.A.2    Dorey, E.L.3    Horton, M.A.4
  • 34
    • 0029837583 scopus 로고    scopus 로고
    • Advances in bone biology: The osteoclast
    • Roodman GD (1996) Advances in bone biology: the osteoclast. Endocr Rev 17:308-332
    • (1996) Endocr Rev , vol.17 , pp. 308-332
    • Roodman, G.D.1
  • 36
    • 0025977548 scopus 로고
    • Congenital osteoclast deficiency in osteopetrotic (op/op) mice is cured by injections of macrophage colony-stimulating factor
    • Kodama H, Yamasaki A, Nose M, Niida S, Ohgame Y, Abe M, Kumegawa M, Suda T (1991) Congenital osteoclast deficiency in osteopetrotic (op/op) mice is cured by injections of macrophage colony-stimulating factor. J Exp Med 173:269-272
    • (1991) J Exp Med , vol.173 , pp. 269-272
    • Kodama, H.1    Yamasaki, A.2    Nose, M.3    Niida, S.4    Ohgame, Y.5    Abe, M.6    Kumegawa, M.7    Suda, T.8
  • 39
    • 0015400563 scopus 로고
    • Bone resorbing activity in supernatant fluid from cultured human peripheral blood leukocytes
    • Horton JE, Raisz LG, Simmons HA, Oppenheim JJ, Mergenhagen SE (1972) Bone resorbing activity in supernatant fluid from cultured human peripheral blood leukocytes. Science 177:793-795
    • (1972) Science , vol.177 , pp. 793-795
    • Horton, J.E.1    Raisz, L.G.2    Simmons, H.A.3    Oppenheim, J.J.4    Mergenhagen, S.E.5
  • 40
    • 0022353748 scopus 로고
    • Purification and partial sequence of human osteoclast-activating factor: Identity with interleukin 1 beta
    • Dewhirst FE, Stashenko PP, Mole JE, Tsurumachi T (1985) Purification and partial sequence of human osteoclast-activating factor: identity with interleukin 1 beta. J Immunol 135:2562-2568
    • (1985) J Immunol , vol.135 , pp. 2562-2568
    • Dewhirst, F.E.1    Stashenko, P.P.2    Mole, J.E.3    Tsurumachi, T.4
  • 41
    • 0032145401 scopus 로고    scopus 로고
    • Cytokines, bone remodeling, and estrogen deficiency: A 1998 update
    • Jilka RL (1998) Cytokines, bone remodeling, and estrogen deficiency: a 1998 update. Bone 23:75-81
    • (1998) Bone , vol.23 , pp. 75-81
    • Jilka, R.L.1
  • 42
    • 0028675659 scopus 로고
    • The interleukin-1 family: 10 years of discovery
    • Dimarello CA (1994) The interleukin-1 family: 10 years of discovery. FASEB J 8:1314-1325
    • (1994) FASEB J , vol.8 , pp. 1314-1325
    • Dimarello, C.A.1
  • 47
    • 0023095815 scopus 로고
    • Tumor necrosis factors alpha and beta induce osteoblastic cells to stimulate osteoclastic bone resorption
    • Thomson BM, Mundy GR, Chambers TJ (1987) Tumor necrosis factors alpha and beta induce osteoblastic cells to stimulate osteoclastic bone resorption. J Immunol 138:775-779
    • (1987) J Immunol , vol.138 , pp. 775-779
    • Thomson, B.M.1    Mundy, G.R.2    Chambers, T.J.3
  • 48
    • 0024239798 scopus 로고
    • Tumor necrosis factor alpha and interleukin-1 stimulate bone resorption in vivo as measured by urinary [3H]tetracycline excretion from prelabeled mice
    • Köning A, Muhlbauer RC, Fleisch H (1988) Tumor necrosis factor alpha and interleukin-1 stimulate bone resorption in vivo as measured by urinary [3H]tetracycline excretion from prelabeled mice. J Bone Miner Res 3:621-627
    • (1988) J Bone Miner Res , vol.3 , pp. 621-627
    • Köning, A.1    Muhlbauer, R.C.2    Fleisch, H.3
  • 49
    • 0030960403 scopus 로고    scopus 로고
    • The functional block of TNF but not of IL-6 prevents bone loss in ovariectomized mice
    • Kimble RB, Bain S, Pacifici R (1997) The functional block of TNF but not of IL-6 prevents bone loss in ovariectomized mice. J Bone Miner Res 12:935-941
    • (1997) J Bone Miner Res , vol.12 , pp. 935-941
    • Kimble, R.B.1    Bain, S.2    Pacifici, R.3
  • 50
    • 0033790375 scopus 로고    scopus 로고
    • Gp130 Cytokine family and bone cells
    • Heymann D, Rousselle AV (2000) gp130 Cytokine family and bone cells. Cytokine 12:1455-1468
    • (2000) Cytokine , vol.12 , pp. 1455-1468
    • Heymann, D.1    Rousselle, A.V.2
  • 51
    • 0025313227 scopus 로고
    • IL-6 stimulates osteoclast-like multinucleated cell formation in long term human marrow cultures by inducing IL-1 release
    • Kurihara N, Bertolini D, Suda T, Akiyama Y, Roodman GD (1990) IL-6 stimulates osteoclast-like multinucleated cell formation in long term human marrow cultures by inducing IL-1 release. J Immunol 144:4226-4230
    • (1990) J Immunol , vol.144 , pp. 4226-4230
    • Kurihara, N.1    Bertolini, D.2    Suda, T.3    Akiyama, Y.4    Roodman, G.D.5
  • 52
    • 0031895576 scopus 로고    scopus 로고
    • IL-6 mediates the effects of IL-1 or TNF, but not PTHrP or 1, 25 (OH) 2D3, on osteoclast-like cell formation in normal human bone marrow cultures
    • Devlin RD, Reddy SV, Savino R, Ciliberto G, Roodman GD (1998) IL-6 mediates the effects of IL-1 or TNF, but not PTHrP or 1, 25 (OH) 2D3, on osteoclast-like cell formation in normal human bone marrow cultures. J Bone Miner Res 13:393-399
    • (1998) J Bone Miner Res , vol.13 , pp. 393-399
    • Devlin, R.D.1    Reddy, S.V.2    Savino, R.3    Ciliberto, G.4    Roodman, G.D.5
  • 55
    • 0031734956 scopus 로고    scopus 로고
    • Murine bone marrow stromally derived BMS2 adipocytes support differentiation and function of osteoclast-like cells in vitro
    • Kelly KA, Tanaka S, Baron R, Gimble JM (1998) Murine bone marrow stromally derived BMS2 adipocytes support differentiation and function of osteoclast-like cells in vitro. Endocrinology 139:2092-2101
    • (1998) Endocrinology , vol.139 , pp. 2092-2101
    • Kelly, K.A.1    Tanaka, S.2    Baron, R.3    Gimble, J.M.4
  • 56
    • 85003152202 scopus 로고
    • Modulation of osteoclast differentiation
    • Suda T, Takahashi N, Martin TJ (1992) Modulation of osteoclast differentiation. Endocr Rev 13:66-80
    • (1992) Endocr Rev , vol.13 , pp. 66-80
    • Suda, T.1    Takahashi, N.2    Martin, T.J.3
  • 60
    • 0035206443 scopus 로고    scopus 로고
    • Minireview: The OPG/RANKL/RANK system
    • Khosla S (2001) Minireview: the OPG/RANKL/RANK system. Endocrinology 142:5050-5055
    • (2001) Endocrinology , vol.142 , pp. 5050-5055
    • Khosla, S.1
  • 61
    • 0034455667 scopus 로고    scopus 로고
    • Clinical review 114: Hot topic. The role of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in the pathogenesis and treatment of metabolic bone diseases
    • Hofbauer LC, Heufelder AE (2000) Clinical review 114: hot topic. The role of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in the pathogenesis and treatment of metabolic bone diseases. J Clin Endocrinol Metab 85:2355-2363
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2355-2363
    • Hofbauer, L.C.1    Heufelder, A.E.2
  • 62
    • 0033304730 scopus 로고    scopus 로고
    • Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
    • Suda T, Takahashi N, Udagawa N, Jimi E, Gillespie MT, Martin TJ (1999) Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev 20:345-357
    • (1999) Endocr Rev , vol.20 , pp. 345-357
    • Suda, T.1    Takahashi, N.2    Udagawa, N.3    Jimi, E.4    Gillespie, M.T.5    Martin, T.J.6
  • 63
    • 0033304632 scopus 로고    scopus 로고
    • Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells
    • Hofbauer LC, Khosla S, Dunstan CR, Lacey DL, Spelsberg TC, Riggs BL (1999) Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells. Endocrinology 140:4367-4370
    • (1999) Endocrinology , vol.140 , pp. 4367-4370
    • Hofbauer, L.C.1    Khosla, S.2    Dunstan, C.R.3    Lacey, D.L.4    Spelsberg, T.C.5    Riggs, B.L.6
  • 72
    • 0033304809 scopus 로고    scopus 로고
    • Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: Potential paracrine mechanisms of glucocorticoid-induced osteoporosis
    • Hofbauer LC, Gori F, Riggs BL, Lacey DL, Dunstan CR, Spelsberg TC, Khosla S (1999) Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis. Endocrinology 140:4382-4389
    • (1999) Endocrinology , vol.140 , pp. 4382-4389
    • Hofbauer, L.C.1    Gori, F.2    Riggs, B.L.3    Lacey, D.L.4    Dunstan, C.R.5    Spelsberg, T.C.6    Khosla, S.7
  • 75
    • 0034735792 scopus 로고    scopus 로고
    • Bone versus immune system
    • Arron JR, Choi Y (2000) Bone versus immune system. Nature 408:535-536
    • (2000) Nature , vol.408 , pp. 535-536
    • Arron, J.R.1    Choi, Y.2
  • 77
    • 0032588998 scopus 로고    scopus 로고
    • Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells
    • Hofbauer LC, Lacey DL, Dunstan CR, Spelsberg TC, Riggs BL, Khosla S (1999) Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells. Bone 25:255-259
    • (1999) Bone , vol.25 , pp. 255-259
    • Hofbauer, L.C.1    Lacey, D.L.2    Dunstan, C.R.3    Spelsberg, T.C.4    Riggs, B.L.5    Khosla, S.6
  • 78
    • 0041836267 scopus 로고    scopus 로고
    • Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator
    • Cenci S, Toraldo G, Weitzmann MN, Roggia C, Gao Y, Qian WP, Sierra O, Pacifici R (2003) Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator. Proc Natl Acad Sci USA 100:10405-10410
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10405-10410
    • Cenci, S.1    Toraldo, G.2    Weitzmann, M.N.3    Roggia, C.4    Gao, Y.5    Qian, W.P.6    Sierra, O.7    Pacifici, R.8
  • 79
    • 0035923727 scopus 로고    scopus 로고
    • Upregulation of TNF-producing T cells in the bone marrow: A key mechanism by which estrogen deficiency induces bone loss in vivo
    • Roggia C, Gao Y, Cenci S, Weitzmann MN, Toraldo G, Isaia G, Pacifici R (2001) Upregulation of TNF-producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo. Proc Natl Acad Sci USA 98:13960-13965
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 13960-13965
    • Roggia, C.1    Gao, Y.2    Cenci, S.3    Weitzmann, M.N.4    Toraldo, G.5    Isaia, G.6    Pacifici, R.7
  • 82
    • 0031955217 scopus 로고    scopus 로고
    • A unitary model for involutional osteoporosis: Estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men
    • Riggs BL, Khosla S, Melton LJ III (1998) A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. J Bone Miner Res 13:763-773
    • (1998) J Bone Miner Res , vol.13 , pp. 763-773
    • Riggs, B.L.1    Khosla, S.2    Melton III, L.J.3
  • 83
    • 0029798819 scopus 로고    scopus 로고
    • Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-beta
    • Hughes DE, Dai A, Tiffee JC, Li HH, Mundy GR, Boyce BF (1996) Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-beta. Nat Med 2:1132-1136
    • (1996) Nat Med , vol.2 , pp. 1132-1136
    • Hughes, D.E.1    Dai, A.2    Tiffee, J.C.3    Li, H.H.4    Mundy, G.R.5    Boyce, B.F.6
  • 84
    • 0025100436 scopus 로고
    • Cancellous bone remodeling in type I (postmenopausal) osteoporosis: Quantitative assessment of rates of formation, resorption, and bone loss at tissue and cellular levels
    • Eriksen EF, Hodgson SF, Eastell R, Cedel SL, O'Fallon WM, Riggs BL (1990) Cancellous bone remodeling in type I (postmenopausal) osteoporosis: quantitative assessment of rates of formation, resorption, and bone loss at tissue and cellular levels. J Bone Miner Res 5:311-319
    • (1990) J Bone Miner Res , vol.5 , pp. 311-319
    • Eriksen, E.F.1    Hodgson, S.F.2    Eastell, R.3    Cedel, S.L.4    O'Fallon, W.M.5    Riggs, B.L.6
  • 87
    • 0032093690 scopus 로고    scopus 로고
    • Cytokines, estrogen, and postmenopausal osteoporosis - The second decade
    • Pacifici R (1998) Cytokines, estrogen, and postmenopausal osteoporosis - the second decade. Endocrinology 139:2659-2661
    • (1998) Endocrinology , vol.139 , pp. 2659-2661
    • Pacifici, R.1
  • 91
    • 0030950131 scopus 로고    scopus 로고
    • Transgenic mice expressing soluble tumor necrosis factor-receptor are protected against bone loss caused by estrogen deficiency
    • Ammann P, Rizzoli R, Bonjour JP, Bourrin S, Meyer JM, Vassalli P, Garcia I (1997) Transgenic mice expressing soluble tumor necrosis factor-receptor are protected against bone loss caused by estrogen deficiency. J Clin Invest 99:1699-1703
    • (1997) J Clin Invest , vol.99 , pp. 1699-1703
    • Ammann, P.1    Rizzoli, R.2    Bonjour, J.P.3    Bourrin, S.4    Meyer, J.M.5    Vassalli, P.6    Garcia, I.7
  • 93
    • 0028824032 scopus 로고
    • Bone marrow neutrophilia and suppressed bone turnover in human interleukin-6 transgenic mice. A cellular relationship among hematopoietic cells, osteoblasts, and osteoclasts mediated by stromal cells in bone marrow
    • Kitamura H, Kawata H, Takahashi F, Higuchi Y, Furuichi T, Ohkawa H (1995) Bone marrow neutrophilia and suppressed bone turnover in human interleukin-6 transgenic mice. A cellular relationship among hematopoietic cells, osteoblasts, and osteoclasts mediated by stromal cells in bone marrow. Am J Pathol 147:1682-1692
    • (1995) Am J Pathol , vol.147 , pp. 1682-1692
    • Kitamura, H.1    Kawata, H.2    Takahashi, F.3    Higuchi, Y.4    Furuichi, T.5    Ohkawa, H.6
  • 95
    • 0036838918 scopus 로고    scopus 로고
    • Role of RANKL and RANK in bone loss and arthritis
    • Jones DH, Kong YY, Penninger JM (2002) Role of RANKL and RANK in bone loss and arthritis. Ann Rheum Dis 61 (Suppl 2): ii32-ii39
    • (2002) Ann Rheum Dis , vol.61 , Issue.SUPPL. 2
    • Jones, D.H.1    Kong, Y.Y.2    Penninger, J.M.3
  • 96
    • 0032855826 scopus 로고    scopus 로고
    • Osteoprotegerin ligand and osteoprotegerin: Novel implications for osteoclast biology and bone metabolism
    • Hofbauer LC (1999) Osteoprotegerin ligand and osteoprotegerin: novel implications for osteoclast biology and bone metabolism. Eur J Endocrinol 141:195-210
    • (1999) Eur J Endocrinol , vol.141 , pp. 195-210
    • Hofbauer, L.C.1
  • 97
    • 0034608813 scopus 로고    scopus 로고
    • Estrogens suppress RANK ligand-induced osteoclast differentiation via a stromal cell independent mechanism involving c-Jun. repression
    • Shevde NK, Bendixen AC, Dienger KM, Pike JW (2000) Estrogens suppress RANK ligand-induced osteoclast differentiation via a stromal cell independent mechanism involving c-Jun. repression. Proc Natl Acad Sci USA 97:7829-7834
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 7829-7834
    • Shevde, N.K.1    Bendixen, A.C.2    Dienger, K.M.3    Pike, J.W.4
  • 98
    • 0035937747 scopus 로고    scopus 로고
    • Estrogen decreases osteoclast formation by down-regulating receptor activator of NF-kappa B ligand (RANKL)-induced JNK activation
    • Srivastava S, Toraldo G, Weitzmann MN, Cenci S, Ross FP, Pacifici R (2001) Estrogen decreases osteoclast formation by down-regulating receptor activator of NF-kappa B ligand (RANKL)-induced JNK activation. J Biol Chem 276:8836-8840
    • (2001) J Biol Chem , vol.276 , pp. 8836-8840
    • Srivastava, S.1    Toraldo, G.2    Weitzmann, M.N.3    Cenci, S.4    Ross, F.P.5    Pacifici, R.6
  • 101
  • 102
    • 0036372440 scopus 로고    scopus 로고
    • Transforming growth factor-beta in T-cell biology
    • Gorelik L, Flavell RA (2002) Transforming growth factor-beta in T-cell biology. Nat Rev Immunol 2:46-53
    • (2002) Nat Rev Immunol , vol.2 , pp. 46-53
    • Gorelik, L.1    Flavell, R.A.2
  • 103
    • 0033028733 scopus 로고    scopus 로고
    • Expression and localization of estrogen receptor-beta in murine and human bone
    • Vidal O, Kindblom LG, Ohlsson C (1999) Expression and localization of estrogen receptor-beta in murine and human bone. J Bone Miner Res 14:923-929
    • (1999) J Bone Miner Res , vol.14 , pp. 923-929
    • Vidal, O.1    Kindblom, L.G.2    Ohlsson, C.3
  • 104
    • 0033305457 scopus 로고    scopus 로고
    • The actions and interactions of sex steroids and growth factors/cytokines on the skeleton
    • Spelsberg TC, Subramaniam M, Riggs BL, Khosla S (1999) The actions and interactions of sex steroids and growth factors/cytokines on the skeleton. Mol Endocrinol 13:819-828
    • (1999) Mol Endocrinol , vol.13 , pp. 819-828
    • Spelsberg, T.C.1    Subramaniam, M.2    Riggs, B.L.3    Khosla, S.4
  • 105
    • 0029802660 scopus 로고    scopus 로고
    • Estrogen deficiency increases the ability of stromal cells to support murine osteoclastogenesis via an interleukin-1and tumor necrosis factor-mediated stimulation of macrophage colony-stimulating factor production
    • Kimble RB, Srivastava S, Ross FP, Matayoshi A, Pacifici R (1996) Estrogen deficiency increases the ability of stromal cells to support murine osteoclastogenesis via an interleukin-1and tumor necrosis factor-mediated stimulation of macrophage colony-stimulating factor production. J Biol Chem 271:28890-28897
    • (1996) J Biol Chem , vol.271 , pp. 28890-28897
    • Kimble, R.B.1    Srivastava, S.2    Ross, F.P.3    Matayoshi, A.4    Pacifici, R.5
  • 106
    • 0029147741 scopus 로고
    • Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP beta
    • Stein B, Yang MX (1995) Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP beta. Mol Cell Biol 15:4971-4979
    • (1995) Mol Cell Biol , vol.15 , pp. 4971-4979
    • Stein, B.1    Yang, M.X.2
  • 107
    • 0031796493 scopus 로고    scopus 로고
    • Estrogen regulation of a transforming growth factor-beta inducible early gene that inhibits deoxyribonucleic acid synthesis in human osteoblasts
    • Tau KR, Hefferan TE, Waters KM, Robinson JA, Subramaniam M, Riggs BL, Spelsberg TC (1998) Estrogen regulation of a transforming growth factor-beta inducible early gene that inhibits deoxyribonucleic acid synthesis in human osteoblasts. Endocrinology 139:1346-1353
    • (1998) Endocrinology , vol.139 , pp. 1346-1353
    • Tau, K.R.1    Hefferan, T.E.2    Waters, K.M.3    Robinson, J.A.4    Subramaniam, M.5    Riggs, B.L.6    Spelsberg, T.C.7
  • 108
    • 0032518282 scopus 로고    scopus 로고
    • Bone morphogenetic protein-6 production in human osteoblastic cell lines. Selective regulation by estrogen
    • Rickard DJ, Hofbauer LC, Bonde SK, Gori F, Spelsberg TC, Riggs BL (1998) Bone morphogenetic protein-6 production in human osteoblastic cell lines. Selective regulation by estrogen. J Clin Invest 101:413-422
    • (1998) J Clin Invest , vol.101 , pp. 413-422
    • Rickard, D.J.1    Hofbauer, L.C.2    Bonde, S.K.3    Gori, F.4    Spelsberg, T.C.5    Riggs, B.L.6
  • 110
    • 0032717624 scopus 로고    scopus 로고
    • Estrogen's bone-protective effects may involve differential IL-1 receptor regulation in human osteoclast-like cells
    • Sunyer T, Lewis J, Collin-Osdoby P, Osdoby P (1999) Estrogen's bone-protective effects may involve differential IL-1 receptor regulation in human osteoclast-like cells. J Clin Invest 103:1409-1418
    • (1999) J Clin Invest , vol.103 , pp. 1409-1418
    • Sunyer, T.1    Lewis, J.2    Collin-Osdoby, P.3    Osdoby, P.4
  • 111
    • 0032694582 scopus 로고    scopus 로고
    • Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun. and JunD
    • Srivastava S, Weitzmann MN, Cenci S, Ross FP, Adler S, Pacifici R (1999) Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun. and JunD. J Clin Invest 104:503-513
    • (1999) J Clin Invest , vol.104 , pp. 503-513
    • Srivastava, S.1    Weitzmann, M.N.2    Cenci, S.3    Ross, F.P.4    Adler, S.5    Pacifici, R.6
  • 112
    • 0026570922 scopus 로고
    • Estrogen maintains trabecular bone volume in rats not only by suppression of bone resorption but also by stimulation of bone formation
    • Chow J, Tobias JH, Colston KW, Chambers TJ (1992) Estrogen maintains trabecular bone volume in rats not only by suppression of bone resorption but also by stimulation of bone formation. J Clin Invest 89:74-78
    • (1992) J Clin Invest , vol.89 , pp. 74-78
    • Chow, J.1    Tobias, J.H.2    Colston, K.W.3    Chambers, T.J.4
  • 113
    • 0033303829 scopus 로고    scopus 로고
    • Estrogen prevents glucocorticoid-induced apoptosis in osteoblasts in vivo and in vitro
    • Gohel A, McCarthy MB, Gronowicz G (1999) Estrogen prevents glucocorticoid-induced apoptosis in osteoblasts in vivo and in vitro. Endocrinology 140:5339-5347
    • (1999) Endocrinology , vol.140 , pp. 5339-5347
    • Gohel, A.1    McCarthy, M.B.2    Gronowicz, G.3
  • 116
    • 0038819062 scopus 로고    scopus 로고
    • Kinase-mediated regulation of common transcription factors accounts for the boneprotective effects of sex steroids
    • Kousteni S, Han L, Chen JR, Almeida M, Plotkin LI, Bellido T, Manolagas SC (2003) Kinase-mediated regulation of common transcription factors accounts for the boneprotective effects of sex steroids. J Clin Invest 111:1651-1664
    • (2003) J Clin Invest , vol.111 , pp. 1651-1664
    • Kousteni, S.1    Han, L.2    Chen, J.R.3    Almeida, M.4    Plotkin, L.I.5    Bellido, T.6    Manolagas, S.C.7
  • 119
    • 0036677998 scopus 로고    scopus 로고
    • Meta-analyses of therapies for postmenopausal osteoporosis. V. Meta-analysis of the efficacy of hormone replacement therapy in treating and preventing osteoporosis in postmenopausal women
    • Wells G, Tugwell P, Shea B, Guyatt G, Peterson J, Zytaruk N, Robinson V, Henry D, O'Connell D, Cranney A (2002) Meta-analyses of therapies for postmenopausal osteoporosis. V. Meta-analysis of the efficacy of hormone replacement therapy in treating and preventing osteoporosis in postmenopausal women. Endocr Rev 23:529-539
    • (2002) Endocr Rev , vol.23 , pp. 529-539
    • Wells, G.1    Tugwell, P.2    Shea, B.3    Guyatt, G.4    Peterson, J.5    Zytaruk, N.6    Robinson, V.7    Henry, D.8    O'Connell, D.9    Cranney, A.10
  • 124
    • 0037138787 scopus 로고    scopus 로고
    • Raloxifene and cardiovascular events in osteoporotic postmenopausal women: Four-year results from the MORE (Multiple Outcomes of Raloxifene Evaluation) randomized trial
    • Barrett-Connor E, Grady D, Sashegyi A, Anderson PW, Cox DA, Hoszowski K, Rautaharju P, Harper KD (2002) Raloxifene and cardiovascular events in osteoporotic postmenopausal women: four-year results from the MORE (Multiple Outcomes of Raloxifene Evaluation) randomized trial. J Am Med Assoc 287:847-857
    • (2002) J Am Med Assoc , vol.287 , pp. 847-857
    • Barrett-Connor, E.1    Grady, D.2    Sashegyi, A.3    Anderson, P.W.4    Cox, D.A.5    Hoszowski, K.6    Rautaharju, P.7    Harper, K.D.8
  • 127
    • 0035950447 scopus 로고    scopus 로고
    • Regulation of human cbfa1 gene transcription in osteoblasts by selective estrogen receptor modulators (SERMs)
    • Tou L, Quibria N, Alexander JM (2001) Regulation of human cbfa1 gene transcription in osteoblasts by selective estrogen receptor modulators (SERMs). Mol Cell Endocrinol 183:71-79
    • (2001) Mol Cell Endocrinol , vol.183 , pp. 71-79
    • Tou, L.1    Quibria, N.2    Alexander, J.M.3
  • 128
    • 0029961569 scopus 로고    scopus 로고
    • Estrogen and raloxifene stimulate transforming growth factor-beta 3 gene expression in rat bone: A potential mechanism for estroge- or raloxifene-mediated bone maintenance
    • Yang NN, Bryant HU, Hardikar S, Sato M, Galvin RJ, Glasebrook AL, Termine JD (1996) Estrogen and raloxifene stimulate transforming growth factor-beta 3 gene expression in rat bone: a potential mechanism for estroge- or raloxifene-mediated bone maintenance. Endocrinology 137:2075-2084
    • (1996) Endocrinology , vol.137 , pp. 2075-2084
    • Yang, N.N.1    Bryant, H.U.2    Hardikar, S.3    Sato, M.4    Galvin, R.J.5    Glasebrook, A.L.6    Termine, J.D.7
  • 129
    • 0038377650 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6), IL-1, receptor activator of nuclear factor kappaB ligand (RANKL) and osteoprotegerin production by human osteoblastic cells: Comparison of the effects of 17-beta oestradiol and raloxifene
    • Cheung J, Mak YT, Papaioannou S, Evans BA, Fogelman I, Hampson G (2003) Interleukin-6 (IL-6), IL-1, receptor activator of nuclear factor kappaB ligand (RANKL) and osteoprotegerin production by human osteoblastic cells: comparison of the effects of 17-beta oestradiol and raloxifene. J Endocrinol 177:423-433
    • (2003) J Endocrinol , vol.177 , pp. 423-433
    • Cheung, J.1    Mak, Y.T.2    Papaioannou, S.3    Evans, B.A.4    Fogelman, I.5    Hampson, G.6
  • 131
    • 0344142469 scopus 로고    scopus 로고
    • Comparative effects of estrogen and antiestrogens on differentiation of osteoblasts in mouse bone marrow culture
    • Qu Q, Harkonen PL, Vaananen HK (1999) Comparative effects of estrogen and antiestrogens on differentiation of osteoblasts in mouse bone marrow culture. J Cell BioChem 73:500-507
    • (1999) J Cell BioChem , vol.73 , pp. 500-507
    • Qu, Q.1    Harkonen, P.L.2    Vaananen, H.K.3
  • 133
    • 0034088850 scopus 로고    scopus 로고
    • Comparative effects of estrogen and raloxifene on B lymphopoiesis and bone loss induced by sex steroid deficiency in mice
    • Onoe Y, Miyaura C, Ito M, Ohta H, Nozawa S, Suda T (2000) Comparative effects of estrogen and raloxifene on B lymphopoiesis and bone loss induced by sex steroid deficiency in mice. J Bone Miner Res 15:541-549
    • (2000) J Bone Miner Res , vol.15 , pp. 541-549
    • Onoe, Y.1    Miyaura, C.2    Ito, M.3    Ohta, H.4    Nozawa, S.5    Suda, T.6
  • 134
    • 0025936415 scopus 로고
    • Isolation of a murine osteoclast colonystimulating factor
    • Lee MY, Eyre DR, Osborne WR (1991) Isolation of a murine osteoclast colonystimulating factor. Proc Natl Acad Sci USA 88:8500-8504
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 8500-8504
    • Lee, M.Y.1    Eyre, D.R.2    Osborne, W.R.3
  • 135
    • 0032578611 scopus 로고    scopus 로고
    • Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines
    • Hofbauer LC, Dunstan CR, Spelsberg TC, Riggs BL, Khosla S (1998) Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines. BioChem Biophys Res Commun 250:776-781
    • (1998) BioChem Biophys Res Commun , vol.250 , pp. 776-781
    • Hofbauer, L.C.1    Dunstan, C.R.2    Spelsberg, T.C.3    Riggs, B.L.4    Khosla, S.5
  • 136
    • 0036312825 scopus 로고    scopus 로고
    • Characterization of the bone-resorptive effect of interleukin-11 in cultured mouse calvarial bones
    • Ahlen J, Andersson S, Mukohyama H, Roth C, Backman A, Conaway HH, Lerner UH (2002) Characterization of the bone-resorptive effect of interleukin-11 in cultured mouse calvarial bones. Bone 31:242-251
    • (2002) Bone , vol.31 , pp. 242-251
    • Ahlen, J.1    Andersson, S.2    Mukohyama, H.3    Roth, C.4    Backman, A.5    Conaway, H.H.6    Lerner, U.H.7
  • 137
    • 0034522704 scopus 로고    scopus 로고
    • Intracellular calcium and protein kinase C mediate expression of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in osteoblasts
    • Takami M, Takahashi N, Udagawa N, Miyaura C, Suda K, Woo JT, Martin TJ, Nagai K, Suda T (2000) Intracellular calcium and protein kinase C mediate expression of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in osteoblasts. Endocrinology 141:4711-4719
    • (2000) Endocrinology , vol.141 , pp. 4711-4719
    • Takami, M.1    Takahashi, N.2    Udagawa, N.3    Miyaura, C.4    Suda, K.5    Woo, J.T.6    Martin, T.J.7    Nagai, K.8    Suda, T.9
  • 138
    • 0032573550 scopus 로고    scopus 로고
    • Potential role of cbfa1, an essential transcriptional factor for osteoblast differentiation, in osteoclastogenesis: Regulation of mRNA expression of osteoclast differentiation factor (ODF)
    • Gao YH, Shinki T, Yuasa T, Kataoka-Enomoto H, Komori T, Suda T, Yamaguchi A (1998) Potential role of cbfa1, an essential transcriptional factor for osteoblast differentiation, in osteoclastogenesis: regulation of mRNA expression of osteoclast differentiation factor (ODF). BioChem Biophys Res Commun 252:697-702
    • (1998) BioChem Biophys Res Commun , vol.252 , pp. 697-702
    • Gao, Y.H.1    Shinki, T.2    Yuasa, T.3    Kataoka-Enomoto, H.4    Komori, T.5    Suda, T.6    Yamaguchi, A.7
  • 139
    • 0037105542 scopus 로고    scopus 로고
    • IL-6, leukemia inhibitory factor, and oncostatin M stimulate bone resorption and regulate the expression of receptor activator of NF-kappa B ligand, osteoprotegerin, and receptor activator of NF-kappa B in mouse calvariae
    • Palmqvist P, Persson E, Conaway HH, Lerner UH (2002) IL-6, leukemia inhibitory factor, and oncostatin M stimulate bone resorption and regulate the expression of receptor activator of NF-kappa B ligand, osteoprotegerin, and receptor activator of NF-kappa B in mouse calvariae. J Immunol 169:3353-3362
    • (2002) J Immunol , vol.169 , pp. 3353-3362
    • Palmqvist, P.1    Persson, E.2    Conaway, H.H.3    Lerner, U.H.4
  • 140
    • 0034618580 scopus 로고    scopus 로고
    • Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-kappaB ligand: Modulation of the expression by osteotropic factors and cytokines
    • Nakashima T, Kobayashi Y, Yamasaki S, Kawakami A, Eguchi K, Sasaki H, Sakai H (2000) Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-kappaB ligand: modulation of the expression by osteotropic factors and cytokines. Biochem Biophys Res Commun 275:768-775
    • (2000) Biochem Biophys Res Commun , vol.275 , pp. 768-775
    • Nakashima, T.1    Kobayashi, Y.2    Yamasaki, S.3    Kawakami, A.4    Eguchi, K.5    Sasaki, H.6    Sakai, H.7
  • 141
    • 0032573559 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 increases mRNA levels of osteoclastogenesis inhibitory factor in osteoblastic/stromal cells and inhibits the survival of murine osteoclast-like cells
    • Murakami T, Yamamoto M, Ono K, Nishikawa M, Nagata N, Motoyoshi K, Akatsu T (1998) Transforming growth factor-beta1 increases mRNA levels of osteoclastogenesis inhibitory factor in osteoblastic/stromal cells and inhibits the survival of murine osteoclast-like cells. Biochem Biophys Res Commun 252:747-752
    • (1998) Biochem Biophys Res Commun , vol.252 , pp. 747-752
    • Murakami, T.1    Yamamoto, M.2    Ono, K.3    Nishikawa, M.4    Nagata, N.5    Motoyoshi, K.6    Akatsu, T.7
  • 143
    • 0034817070 scopus 로고    scopus 로고
    • Effects of immunosuppressants on receptor activator of NF-kappaB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells
    • Hofbauer LC, Shui C, Riggs BL, Dunstan CR, Spelsberg TC, O'Brien T, Khosla S (2001) Effects of immunosuppressants on receptor activator of NF-kappaB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells. Biochem Biophys Res Commun 280:334-339
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 334-339
    • Hofbauer, L.C.1    Shui, C.2    Riggs, B.L.3    Dunstan, C.R.4    Spelsberg, T.C.5    O'Brien, T.6    Khosla, S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.