Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-γ-induced class II transactivator

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 18, 2003, Pages 10405-10410

  Cenci, Simone ^a,b   Toraldo, Gianluca ^c   Weitzmann, M Neale ^a   Roggia, Cristiana ^a   Gao, Yuhao ^a   Qian, Wei Ping ^a,c   Sierra, Oscar ^c   Pacifici, Roberto ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c BARNES JEWISH HOSPITAL   (United States)

Author keywords

Osteoporosis; Ovariectomy; Sex steroids; Tumor necrosis factor

Indexed keywords

CYTOKINE; ESTROGEN; GAMMA INTERFERON INDUCED CLASS 2 TRANSACTIVATOR; GAMMA INTERFERON RECEPTOR; INTERLEUKIN 12; INTERLEUKIN 18; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ESTROGEN DEFICIENCY; FEMALE; GENE CONTROL; IMMUNOMODULATION; IN VIVO STUDY; LIFESPAN; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MOUSE; NONHUMAN; OSTEOLYSIS; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN FUNCTION; TH1 CELL; UPREGULATION;

ANIMALS; ANTIGEN-PRESENTING CELLS; ESTROGENS; INTERFERON TYPE II; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NUCLEAR PROTEINS; OSTEOPOROSIS; OVARIECTOMY; RECEPTORS, INTERFERON; T-LYMPHOCYTES; TRANS-ACTIVATORS;

ANIMALIA;

EID: 0041836267     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1533207100     Document Type: Article

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