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Volumn 99, Issue 7, 1997, Pages 1699-1703

Transgenic mice expressing soluble tumor necrosis factor-receptor are protected against bone loss caused by estrogen deficiency

Author keywords

biomechanics; DXA; osteocalcin; osteoporosis; pathophysiology

Indexed keywords

OSTEOCALCIN; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 0030950131     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119333     Document Type: Article
Times cited : (275)

References (35)
  • 1
    • 0022648104 scopus 로고
    • Stimulation of bone resorption and inhibition of bone formation in vitro by human tumor necrosis factors
    • Bertolini, D.R., G.E. Nedwin, T.S. Bringman, D.D. Smith, and G.R. Mundy. 1986. Stimulation of bone resorption and inhibition of bone formation in vitro by human tumor necrosis factors. Nature (Lond.). 319:516-518.
    • (1986) Nature (Lond.) , vol.319 , pp. 516-518
    • Bertolini, D.R.1    Nedwin, G.E.2    Bringman, T.S.3    Smith, D.D.4    Mundy, G.R.5
  • 2
    • 0026770902 scopus 로고
    • Production of various cytokines by normal human osteoblast-like cells in response to interleukin-1β and tumor necrosis factor-α: Lack of regulation by 17β-estradiol
    • Chaudhary, L.R., T.C. Spelsberg, and B.L.P. Riggs. 1992. Production of various cytokines by normal human osteoblast-like cells in response to interleukin-1β and tumor necrosis factor-α: lack of regulation by 17β-estradiol. Endocrinology. 130:2528-2534.
    • (1992) Endocrinology , vol.130 , pp. 2528-2534
    • Chaudhary, L.R.1    Spelsberg, T.C.2    Riggs, B.L.P.3
  • 3
    • 0024523310 scopus 로고
    • Tumors producing human tumor necrosis factor induce hypercalcemia and osteoclastic bone resorption in nude mice
    • Johnson, R.A., B.F. Boyce, G.R. Mundy, and G.D. Roodman. 1989. Tumors producing human tumor necrosis factor induce hypercalcemia and osteoclastic bone resorption in nude mice. Endocrinology. 124:1424-1427.
    • (1989) Endocrinology , vol.124 , pp. 1424-1427
    • Johnson, R.A.1    Boyce, B.F.2    Mundy, G.R.3    Roodman, G.D.4
  • 4
    • 0028362416 scopus 로고
    • Osteonal and hemi-osteonal remodeling: The spatial and temporal framework for signal traffic in adult human bone
    • Parfitt, A.M. 1994. Osteonal and hemi-osteonal remodeling: the spatial and temporal framework for signal traffic in adult human bone. J. Cell. Biochem. 55:273-286.
    • (1994) J. Cell. Biochem. , vol.55 , pp. 273-286
    • Parfitt, A.M.1
  • 6
    • 0026068145 scopus 로고
    • The ovariectomized rat model of postmenopausal bone loss
    • Kalu, D.N. 1991. The ovariectomized rat model of postmenopausal bone loss. Bone Miner. 15:175-191.
    • (1991) Bone Miner. , vol.15 , pp. 175-191
    • Kalu, D.N.1
  • 7
    • 0027168210 scopus 로고
    • Long-term osteopenic changes in cancellous bone structure in ovariectomized rats
    • Miller, S.C., and T.J. Wronski. 1992. Long-term osteopenic changes in cancellous bone structure in ovariectomized rats. Anat. Rec. 236:433-441.
    • (1992) Anat. Rec. , vol.236 , pp. 433-441
    • Miller, S.C.1    Wronski, T.J.2
  • 9
    • 0025896935 scopus 로고
    • Chinese hamster ovarian cells transfected with the murine interleukin-6 gene cause hypercalcemia as well as cachexia, leukocytosis and thrombocytosis in tumor-bearing nude mice
    • Black, K., I.R. Garrett, and G.R. Mundy. 1991. Chinese hamster ovarian cells transfected with the murine interleukin-6 gene cause hypercalcemia as well as cachexia, leukocytosis and thrombocytosis in tumor-bearing nude mice. Endocrinology. 128:2657-2659.
    • (1991) Endocrinology , vol.128 , pp. 2657-2659
    • Black, K.1    Garrett, I.R.2    Mundy, G.R.3
  • 11
    • 0026516415 scopus 로고
    • 17β estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: A potential mechanism for the antiosteoporotic effect of estrogens
    • Girasole, G., R.L. Jilka, G. Passeri, S. Boswell, G. Boder, D.C. Williams, and S.C. Manolagas. 1992. 17β estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens. J. Clin. Invest. 89:883-891.
    • (1992) J. Clin. Invest. , vol.89 , pp. 883-891
    • Girasole, G.1    Jilka, R.L.2    Passeri, G.3    Boswell, S.4    Boder, G.5    Williams, D.C.6    Manolagas, S.C.7
  • 12
    • 0027174296 scopus 로고
    • Cytokines and estrogen in bone: Anti-osteoporotic effects
    • Horowitz, M.C. 1993. Cytokines and estrogen in bone: anti-osteoporotic effects. Science (Wash. DC). 260:626-627.
    • (1993) Science (Wash. DC) , vol.260 , pp. 626-627
    • Horowitz, M.C.1
  • 13
    • 0028925088 scopus 로고
    • Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis
    • Manolagas, S.C., and R.L. Jilka. 1995. Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis. N. Engl. J. Med. 332:305-311.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 305-311
    • Manolagas, S.C.1    Jilka, R.L.2
  • 17
    • 0027423242 scopus 로고
    • Monocytic secretion of interleukin-1 receptor antagonist in normal and osteoporotic women: Effects of menopause and estrogen/progesterone therapy
    • Pacifici, R., J.L. Vannice, L. Rifas, and R.B. Kimble. 1993. Monocytic secretion of interleukin-1 receptor antagonist in normal and osteoporotic women: effects of menopause and estrogen/progesterone therapy. J. Clin. Endocrinol. Metab. 77:1135-1141.
    • (1993) J. Clin. Endocrinol. Metab. , vol.77 , pp. 1135-1141
    • Pacifici, R.1    Vannice, J.L.2    Rifas, L.3    Kimble, R.B.4
  • 19
    • 0029131488 scopus 로고
    • Transgenic mice expressing high levels of soluble TNF-R1 fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections
    • Garcia, I., Y. Miyazaki, K. Araki, R. Lucas, G.E. Grau, G. Milon, Y. Belkaid, C. Montixi, W. Lesslauer, and P. Vassalli. 1995. Transgenic mice expressing high levels of soluble TNF-R1 fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections. Eur. J. Immunology 25:2401-2407.
    • (1995) Eur. J. Immunology , vol.25 , pp. 2401-2407
    • Garcia, I.1    Miyazaki, Y.2    Araki, K.3    Lucas, R.4    Grau, G.E.5    Milon, G.6    Belkaid, Y.7    Montixi, C.8    Lesslauer, W.9    Vassalli, P.10
  • 20
    • 0026596410 scopus 로고
    • Sequential and precise in vivo measurement of bone mineral density in rats using dual-energy X-ray absorptiometry
    • Ammann, P., R. Rizzoli, D. Slosman, and J.P. Bonjour. 1992. Sequential and precise in vivo measurement of bone mineral density in rats using dual-energy X-ray absorptiometry. J. Bone Miner. Res. 7:311-316.
    • (1992) J. Bone Miner. Res. , vol.7 , pp. 311-316
    • Ammann, P.1    Rizzoli, R.2    Slosman, D.3    Bonjour, J.P.4
  • 21
    • 0029898269 scopus 로고    scopus 로고
    • Bone density and shape as determinants of bone strength in IGF-I and/or pamidronate-treated ovariectomized rats
    • Ammann, P., R. Rizzoli, J.-M. Meyer, and J.-P. Bonjour. 1996. Bone density and shape as determinants of bone strength in IGF-I and/or pamidronate-treated ovariectomized rats. Osteoporosis Inf. 6:219-227.
    • (1996) Osteoporosis Inf. , vol.6 , pp. 219-227
    • Ammann, P.1    Rizzoli, R.2    Meyer, J.-M.3    Bonjour, J.-P.4
  • 22
    • 0028970831 scopus 로고
    • Effects of physical training on bone adaptation in three zones of the rat tibia
    • Bourrin, S., S. Palle, R. Pupier, L. Vico, and C. Alexandre. 1995. Effects of physical training on bone adaptation in three zones of the rat tibia. J. Bone Miner. Res. 10: 1745-1752.
    • (1995) J. Bone Miner. Res. , vol.10 , pp. 1745-1752
    • Bourrin, S.1    Palle, S.2    Pupier, R.3    Vico, L.4    Alexandre, C.5
  • 23
    • 0023488581 scopus 로고
    • Bone histomorphometry: Standardization of nomenclature, symbols and units
    • Parfitt, A.M. 1987. Bone histomorphometry: standardization of nomenclature, symbols and units. J. Bone Miner. Res. 2:595-610.
    • (1987) J. Bone Miner. Res. , vol.2 , pp. 595-610
    • Parfitt, A.M.1
  • 24
    • 0001817786 scopus 로고
    • Stereologic basis of bone histomorphometry: Theory of quantitative microscopy and reconstruction of the third dimension
    • R.R. Recker, editor. CRC Press. Boca Raton. FL
    • Parfitt, A.M. 1983. Stereologic basis of bone histomorphometry: theory of quantitative microscopy and reconstruction of the third dimension. In Bone Histomorphometry: Techniques and Interpretation. R.R. Recker, editor. CRC Press. Boca Raton. FL. 53-89.
    • (1983) Bone Histomorphometry: Techniques and Interpretation , pp. 53-89
    • Parfitt, A.M.1
  • 26
    • 85036446790 scopus 로고
    • Interleukin-1 beta gene deletion ("knock-out") does not reduce bone loss in ovariectomized mice
    • Gentile, M., R. Balena, H. Chen, and G.A. Rodan. 1995. Interleukin-1 beta gene deletion ("knock-out") does not reduce bone loss in ovariectomized mice. J. Bone Miner. Res. 10:s364.
    • (1995) J. Bone Miner. Res. , vol.10
    • Gentile, M.1    Balena, R.2    Chen, H.3    Rodan, G.A.4
  • 27
    • 0028151432 scopus 로고
    • Interleukin-1 receptor antagonist and tumor necrosis factor binding protein decrease osteoclast formation and bone resorption in ovariectomized mice
    • Kitazawa, R., R.B. Kimble, J.L. Vannice, V.T. Kung, and R. Pacifici. 1994. Interleukin-1 receptor antagonist and tumor necrosis factor binding protein decrease osteoclast formation and bone resorption in ovariectomized mice. J. Clin. Invest. 94:2397-2406.
    • (1994) J. Clin. Invest. , vol.94 , pp. 2397-2406
    • Kitazawa, R.1    Kimble, R.B.2    Vannice, J.L.3    Kung, V.T.4    Pacifici, R.5
  • 28
    • 0029054872 scopus 로고
    • Simulatneous block of interleukin-1 and tumor necrosis factor is required to completely prevent bone loss in the early postovariectomy period
    • Kimble, R.B., A.B. Matayoshi, J.L. Vannice, V.T. Kung, C. Williams, and R. Pacifici. 1995. Simulatneous block of interleukin-1 and tumor necrosis factor is required to completely prevent bone loss in the early postovariectomy period. Endocrinology. 136:3054-3061.
    • (1995) Endocrinology , vol.136 , pp. 3054-3061
    • Kimble, R.B.1    Matayoshi, A.B.2    Vannice, J.L.3    Kung, V.T.4    Williams, C.5    Pacifici, R.6
  • 29
    • 0025107432 scopus 로고
    • Macrophage colony stimulating factor restores in vivo bone resorption in the OP/OP osteopetrotic mouse
    • Felix, R., M.G. Cecchini, and H. Fleisch. 1990. Macrophage colony stimulating factor restores in vivo bone resorption in the OP/OP osteopetrotic mouse. Endocrinology. 127:2592-2594.
    • (1990) Endocrinology , vol.127 , pp. 2592-2594
    • Felix, R.1    Cecchini, M.G.2    Fleisch, H.3
  • 31
    • 1842283615 scopus 로고
    • Inhibition of IL-6 activity in genetically normal mice does not prevent ovariectomy-induced bone loss
    • Kimble. R.B., S.D. Bain, V. Kung, and R. Pacifici. 1995. Inhibition of IL-6 activity in genetically normal mice does not prevent ovariectomy-induced bone loss. J. Bone Miner. Res. 10:S160.
    • (1995) J. Bone Miner. Res. , vol.10
    • Kimble, R.B.1    Bain, S.D.2    Kung, V.3    Pacifici, R.4
  • 32
    • 0028786577 scopus 로고
    • Interleukin (IL-6) induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors
    • Udagawa, N., N. Takahashi, T. Katagiri, T. Tamura, S. Wada, D.M. Findlay, T.J. Martin, H. Hirota, T. Tada, T. Kishimoto, and T. Suda. 1995. Interleukin (IL-6) induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors. J. Exp. Med. 182:1461-1468.
    • (1995) J. Exp. Med. , vol.182 , pp. 1461-1468
    • Udagawa, N.1    Takahashi, N.2    Katagiri, T.3    Tamura, T.4    Wada, S.5    Findlay, D.M.6    Martin, T.J.7    Hirota, H.8    Tada, T.9    Kishimoto, T.10    Suda, T.11
  • 33
    • 0025979013 scopus 로고
    • Production of granulocyte-macrophage (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) by rat clonal osteoblastic cell line IRC 10/30-mycl stimulated by tumor necrosis factor-alpha
    • Felix, R., M.G. Cecchini, W. Hofstetter, H.L. Guenther, and H. Fleisch. 1991. Production of granulocyte-macrophage (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) by rat clonal osteoblastic cell line IRC 10/30-mycl stimulated by tumor necrosis factor-alpha. Endocrinology. 128:661-667.
    • (1991) Endocrinology , vol.128 , pp. 661-667
    • Felix, R.1    Cecchini, M.G.2    Hofstetter, W.3    Guenther, H.L.4    Fleisch, H.5
  • 34
    • 0026717674 scopus 로고
    • The pathophysiology of tumor necrosis factors
    • Vassalli, P. 1992. The pathophysiology of tumor necrosis factors. Annu. Rev. Immunol. 10.411-452.
    • (1992) Annu. Rev. Immunol. , vol.10 , pp. 411-452
    • Vassalli, P.1
  • 35
    • 0026005559 scopus 로고
    • Involement of a nuclear factor-kappa B-like protein in induction of the macrophage colony-stimulating factor gene by tumor necrosis factor
    • Yamada, H., S. Iwase, M. Mohri, and D. Kufe. 1991. Involement of a nuclear factor-kappa B-like protein in induction of the macrophage colony-stimulating factor gene by tumor necrosis factor. Blood. 78 (8):1988-1995.
    • (1991) Blood , vol.78 , Issue.8 , pp. 1988-1995
    • Yamada, H.1    Iwase, S.2    Mohri, M.3    Kufe, D.4


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