메뉴 건너뛰기




Volumn 141, Issue 3, 1999, Pages 195-210

Osteoprotegerin ligand and osteoprotegerin: Novel implications for osteoclast biology and bone metabolism

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE RECEPTOR; LIGAND;

EID: 0032855826     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1410195     Document Type: Review
Times cited : (120)

References (88)
  • 3
    • 0029837583 scopus 로고    scopus 로고
    • Advances in bone biology: The osteoclast
    • Roodman GR. Advances in bone biology: the osteoclast. Endocrine Reviews 1996 17 308-332.
    • (1996) Endocrine Reviews , vol.17 , pp. 308-332
    • Roodman, G.R.1
  • 5
    • 0029783770 scopus 로고    scopus 로고
    • Estrogen, cytokines, and pathogenesis of postmenopausal osteoporosis
    • Pacifici R. Estrogen, cytokines, and pathogenesis of postmenopausal osteoporosis. Journal of Bone and Mineral Research 1996 11 1043-1051.
    • (1996) Journal of Bone and Mineral Research , vol.11 , pp. 1043-1051
    • Pacifici, R.1
  • 6
    • 0028925088 scopus 로고
    • Bone marrow, cytokines, and bone remodeling: Emerging insights into the pathophysiology of osteoporosis
    • Manolagas SC & Jilka RL. Bone marrow, cytokines, and bone remodeling: emerging insights into the pathophysiology of osteoporosis. New England Journal of Medicine 1995 332 305-311.
    • (1995) New England Journal of Medicine , vol.332 , pp. 305-311
    • Manolagas, S.C.1    Jilka, R.L.2
  • 7
    • 0032145401 scopus 로고    scopus 로고
    • Cytokines, bone remodeling, and estrogen deficiency: A 1998 update
    • Jilka RL. Cytokines, bone remodeling, and estrogen deficiency: a 1998 update. Bone 1998 23 75-81.
    • (1998) Bone , vol.23 , pp. 75-81
    • Jilka, R.L.1
  • 8
    • 0031005576 scopus 로고    scopus 로고
    • Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
    • Simonet WS, Lacey DL, Dunstan CR, Kelley M, Chang M-S, Lüthy R et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 1997 89 309-319.
    • (1997) Cell , vol.89 , pp. 309-319
    • Simonet, W.S.1    Lacey, D.L.2    Dunstan, C.R.3    Kelley, M.4    Chang, M.-S.5    Lüthy, R.6
  • 9
    • 0009660825 scopus 로고    scopus 로고
    • Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): A mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro
    • Yasuda H, Shima N, Nakagawa N, Mochizuki S-I, Yano K, Fujise N et al. Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro. Endocrinology 1998 139 1329-1337.
    • (1998) Endocrinology , vol.139 , pp. 1329-1337
    • Yasuda, H.1    Shima, N.2    Nakagawa, N.3    Mochizuki, S.-I.4    Yano, K.5    Fujise, N.6
  • 10
    • 0032540319 scopus 로고    scopus 로고
    • Osteoprotegerin (OPG) ligand is a cytokine that regulates osteoclast differentiation and activation
    • Lacey DL, Timms E, Tan H-L, Kelley MJ, Dunstan CR, Burgess T et al. Osteoprotegerin (OPG) ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 1998 93 165-176.
    • (1998) Cell , vol.93 , pp. 165-176
    • Lacey, D.L.1    Timms, E.2    Tan, H.-L.3    Kelley, M.J.4    Dunstan, C.R.5    Burgess, T.6
  • 12
    • 0031786789 scopus 로고    scopus 로고
    • TNF-related ligands and their receptors
    • Orlinick JR & Chao MV. TNF-related ligands and their receptors. Cellular Signalling 1998 10 543-551.
    • (1998) Cellular Signalling , vol.10 , pp. 543-551
    • Orlinick, J.R.1    Chao, M.V.2
  • 13
    • 0031578808 scopus 로고    scopus 로고
    • Characterization of a novel TNF-like ligand and recently described TNF ligand and TNF receptor superfamily genes and their constitutive and inducible expression in hematopoietic and non-hematopoietic cells
    • Tan KB, Harrop J, Reddy M, Young P, Terrett J, Emery J et al. Characterization of a novel TNF-like ligand and recently described TNF ligand and TNF receptor superfamily genes and their constitutive and inducible expression in hematopoietic and non-hematopoietic cells. Gene 1997 204 35-46.
    • (1997) Gene , vol.204 , pp. 35-46
    • Tan, K.B.1    Harrop, J.2    Reddy, M.3    Young, P.4    Terrett, J.5    Emery, J.6
  • 14
    • 17344381882 scopus 로고    scopus 로고
    • TR1, a new member of the tumor necrosis factor receptor family, induces fibroblast proliferation and inhibits osteoclastogenesis and bone resorption
    • Kwon BS, Wang S, Udagawa N, Haridas V, Lee ZH, Kim KK et al. TR1, a new member of the tumor necrosis factor receptor family, induces fibroblast proliferation and inhibits osteoclastogenesis and bone resorption. FASEB Journal 1998 12 845-854.
    • (1998) FASEB Journal , vol.12 , pp. 845-854
    • Kwon, B.S.1    Wang, S.2    Udagawa, N.3    Haridas, V.4    Lee, Z.H.5    Kim, K.K.6
  • 16
    • 0032400933 scopus 로고    scopus 로고
    • OPG/FDCR-1, a TNF receptor family member, is expressed in lymphoid cells and is up-regulated by ligating CD40
    • Yun TJ, Chaudhary PM, Shu GL, Frazer JK, Ewings MK, Schwartz SM et al. OPG/FDCR-1, a TNF receptor family member, is expressed in lymphoid cells and is up-regulated by ligating CD40. Journal of Immunology 1998 161 6113-6121.
    • (1998) Journal of Immunology , vol.161 , pp. 6113-6121
    • Yun, T.J.1    Chaudhary, P.M.2    Shu, G.L.3    Frazer, J.K.4    Ewings, M.K.5    Schwartz, S.M.6
  • 19
    • 0032525912 scopus 로고    scopus 로고
    • Cloning and characterization of the gene encoding human osteoprotegerin/osteoclastogenesis-inhibitory factor
    • Morinaga T, Nakagawa N, Yasuda H, Tsuda E & Higashio K. Cloning and characterization of the gene encoding human osteoprotegerin/osteoclastogenesis-inhibitory factor. European Journal of Biochemistry 1998 254 685-691.
    • (1998) European Journal of Biochemistry , vol.254 , pp. 685-691
    • Morinaga, T.1    Nakagawa, N.2    Yasuda, H.3    Tsuda, E.4    Higashio, K.5
  • 20
    • 0032581538 scopus 로고    scopus 로고
    • Structure of the mouse osteoclastogenesis inhibitory factor/osteoprotegerin gene and its expression in embryogenesis
    • Mizuno A, Murakami A, Nakagawa N, Yasuda H, Tsuda E, Morinaga T et al. Structure of the mouse osteoclastogenesis inhibitory factor/osteoprotegerin gene and its expression in embryogenesis. Gene 1998 215 339-343.
    • (1998) Gene , vol.215 , pp. 339-343
    • Mizuno, A.1    Murakami, A.2    Nakagawa, N.3    Yasuda, H.4    Tsuda, E.5    Morinaga, T.6
  • 22
    • 0031721590 scopus 로고    scopus 로고
    • Osteoprotegerin mRNA is expressed in primary human osteoblast-like cells: Down-regulation by glucocorticoids
    • Vidal NOA, Brändström H, Jonsson KB & Ohlsson C. Osteoprotegerin mRNA is expressed in primary human osteoblast-like cells: down-regulation by glucocorticoids. Journal of Endocrinology 1998 159 191-195.
    • (1998) Journal of Endocrinology , vol.159 , pp. 191-195
    • Vidal, N.O.A.1    Brändström, H.2    Jonsson, K.B.3    Ohlsson, C.4
  • 23
    • 0033304809 scopus 로고    scopus 로고
    • Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: Potential paracrine mechanisms of glucocorticoid-induced osteoporosis
    • In Press
    • Hofbauer LC, Gori F, Riggs BL, Dunstan CR, Lacey DL, Spelsberg TC & Khosla S. Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: Potential paracrine mechanisms of glucocorticoid-induced osteoporosis. Endocrinology 1999 (In Press).
    • (1999) Endocrinology
    • Hofbauer, L.C.1    Gori, F.2    Riggs, B.L.3    Dunstan, C.R.4    Lacey, D.L.5    Spelsberg, T.C.6    Khosla, S.7
  • 24
    • 0344098459 scopus 로고    scopus 로고
    • Estrogen stimulates production of the anti-resorptive cytokine receptor osteoprotegerin in human osteoblastic cells
    • In Press
    • Hofbauer LC, Khosla S, Dunstan CR, Spelsberg TC & Riggs BL. Estrogen stimulates production of the anti-resorptive cytokine receptor osteoprotegerin in human osteoblastic cells. Endocrinology 1999 (In Press).
    • (1999) Endocrinology
    • Hofbauer, L.C.1    Khosla, S.2    Dunstan, C.R.3    Spelsberg, T.C.4    Riggs, B.L.5
  • 29
    • 0342771125 scopus 로고    scopus 로고
    • Recombinant osteoprotegerin (OPG), a novel TNF-receptor family member, inhibits in vitro murine osteoclast formation from bone marrow precursors
    • Abstract no. P213
    • Tan H-L, Van G, Scully S, Shimamoto G, Kelley M, Boyle B et al. Recombinant osteoprotegerin (OPG), a novel TNF-receptor family member, inhibits in vitro murine osteoclast formation from bone marrow precursors. Journal of Bone and Mineral Research 1997 12 (Suppl 1) S155 (Abstract no. P213).
    • (1997) Journal of Bone and Mineral Research , vol.12 , Issue.SUPPL. 1
    • Tan, H.-L.1    Van, G.2    Scully, S.3    Shimamoto, G.4    Kelley, M.5    Boyle, B.6
  • 32
  • 33
    • 0032494113 scopus 로고    scopus 로고
    • TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts
    • Fuller K, Wong B, Fox S, Choi Y & Chambers TJ. TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts. Journal of Experimental Medicine 1998 188 997-1001.
    • (1998) Journal of Experimental Medicine , vol.188 , pp. 997-1001
    • Fuller, K.1    Wong, B.2    Fox, S.3    Choi, Y.4    Chambers, T.J.5
  • 34
    • 0001480937 scopus 로고    scopus 로고
    • Osteoprotegerin (OPG), a novel TNF-receptor family member, profoundly inhibits endosteal bone resorption due to growth, humoral hypercalcemia of malignancy, and interleukin 1
    • Abstract no. 134
    • Dunstan CR, Capparelli C, Kelley M, Shimamoto G, Kaufman S, Russell D et al. Osteoprotegerin (OPG), a novel TNF-receptor family member, profoundly inhibits endosteal bone resorption due to growth, humoral hypercalcemia of malignancy, and interleukin 1. Journal of Bone and Mineral Research 1997 12 (Suppl 1) S136 (Abstract no. 134).
    • (1997) Journal of Bone and Mineral Research , vol.12 , Issue.SUPPL. 1
    • Dunstan, C.R.1    Capparelli, C.2    Kelley, M.3    Shimamoto, G.4    Kaufman, S.5    Russell, D.6
  • 35
    • 0031762476 scopus 로고    scopus 로고
    • Hypocalcemic effect of osteoclastogenesis inhibitory factor/osteoprotegerin in the thyroparathyroidectomized rat
    • Yamamoto M, Murakami T, Nishikawa M, Tsuda E, Mochizuki S-I, Higashio K et al. Hypocalcemic effect of osteoclastogenesis inhibitory factor/osteoprotegerin in the thyroparathyroidectomized rat. Endocrinology 1998 139 4012-4015.
    • (1998) Endocrinology , vol.139 , pp. 4012-4015
    • Yamamoto, M.1    Murakami, T.2    Nishikawa, M.3    Tsuda, E.4    Mochizuki, S.-I.5    Higashio, K.6
  • 36
    • 0032404069 scopus 로고    scopus 로고
    • Osteoclastogenesis inhibitory factor exhibits hypocalcemic effects in normal mice and in hypercalcemic nude mice carrying tumors associated with humoral hypercalcemia of malignancy
    • Akatsu T, Murakami T, Ono K, Nishikawa M, Tsuda E, Mochizuki S-I et al. Osteoclastogenesis inhibitory factor exhibits hypocalcemic effects in normal mice and in hypercalcemic nude mice carrying tumors associated with humoral hypercalcemia of malignancy. Bone 1998 23 495-498.
    • (1998) Bone , vol.23 , pp. 495-498
    • Akatsu, T.1    Murakami, T.2    Ono, K.3    Nishikawa, M.4    Tsuda, E.5    Mochizuki, S.-I.6
  • 39
    • 0031735152 scopus 로고    scopus 로고
    • Osteotropic agents regulate the expression of osteoclast differentiation factor and osteoprotegerin in osteoblastic stromal cells
    • Horwood NJ, Elliott J, Martin TJ & Gillespie MT. Osteotropic agents regulate the expression of osteoclast differentiation factor and osteoprotegerin in osteoblastic stromal cells. Endocrinology 1998 139 4743-4746.
    • (1998) Endocrinology , vol.139 , pp. 4743-4746
    • Horwood, N.J.1    Elliott, J.2    Martin, T.J.3    Gillespie, M.T.4
  • 40
    • 0032573559 scopus 로고    scopus 로고
    • Transforming growth factor-β1 increases mRNA levels of osteoclastogenesis inhibitory factor in osteoblastic/stromal cells and inhibits the survival of murine osteoclast-like cells
    • Murakami T, Yamamoto M, Yamamoto M, Ono K, Nishikawa M, Nagata N et al. Transforming growth factor-β1 increases mRNA levels of osteoclastogenesis inhibitory factor in osteoblastic/stromal cells and inhibits the survival of murine osteoclast-like cells. Biochemical and Biophysical Research Communications 1998 252 747-752.
    • (1998) Biochemical and Biophysical Research Communications , vol.252 , pp. 747-752
    • Murakami, T.1    Yamamoto, M.2    Yamamoto, M.3    Ono, K.4    Nishikawa, M.5    Nagata, N.6
  • 41
    • 0026737258 scopus 로고
    • Release of soluble receptors for tumor necrosis factor (TNF) in relation to circulating TNF during experimental endotoxinemia
    • Spinas GA, Keller U & Brockhaus M. Release of soluble receptors for tumor necrosis factor (TNF) in relation to circulating TNF during experimental endotoxinemia. Journal of Clinical Investigation 1992 90 533-536.
    • (1992) Journal of Clinical Investigation , vol.90 , pp. 533-536
    • Spinas, G.A.1    Keller, U.2    Brockhaus, M.3
  • 43
    • 0023764033 scopus 로고
    • Transforming growth factor beta inhibits bone resorption in fetal rat long bone cultures
    • Pfeilschifter J, Seyedin SM & Mundy GR. Transforming growth factor beta inhibits bone resorption in fetal rat long bone cultures. Journal of Clinical Investigation 1988 82 680-685.
    • (1988) Journal of Clinical Investigation , vol.82 , pp. 680-685
    • Pfeilschifter, J.1    Seyedin, S.M.2    Mundy, G.R.3
  • 44
    • 0032538566 scopus 로고    scopus 로고
    • Transforming growth factor-β stimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cells
    • Takai H, Kanematsu M, Yano K, Tsuda E, Higashio K, Ikeda K et al. Transforming growth factor-β stimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cells. Journal of Biological Chemistry 1998 273 27091-27096.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 27091-27096
    • Takai, H.1    Kanematsu, M.2    Yano, K.3    Tsuda, E.4    Higashio, K.5    Ikeda, K.6
  • 46
    • 14444272043 scopus 로고    scopus 로고
    • TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-jun N-terminal kinase in T cells
    • Wong BR, Rho J, Arron J, Robinson E, Orlinick J, Chao M et al. TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-jun N-terminal kinase in T cells. Journal of Biological Chemistry 1997 272 25190-25194.
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 25190-25194
    • Wong, B.R.1    Rho, J.2    Arron, J.3    Robinson, E.4    Orlinick, J.5    Chao, M.6
  • 48
    • 0032588998 scopus 로고    scopus 로고
    • Interleukin-1β and tumor necrosis factor-α, but not interleukin-6 stimulate osteoprotegerin ligand mRNA levels in human osteoblastic cells
    • In Press
    • Hofbauer LC, Lacey DL, Dunstan CR, Spelsberg TC, Riggs BL & Khosla S. Interleukin-1β and tumor necrosis factor-α, but not interleukin-6 stimulate osteoprotegerin ligand mRNA levels in human osteoblastic cells. Bone 1999 24 (In Press).
    • (1999) Bone , vol.24
    • Hofbauer, L.C.1    Lacey, D.L.2    Dunstan, C.R.3    Spelsberg, T.C.4    Riggs, B.L.5    Khosla, S.6
  • 49
    • 0000986684 scopus 로고    scopus 로고
    • Identification of an OSF-2 binding site in the murine RANKL/OPGL gene promoter: A potential link between osteoblastogenesis and osteoclastogenesis
    • Abstract no. 1003
    • O'Brien CA, Farrar NC & Manolagas SC. Identification of an OSF-2 binding site in the murine RANKL/OPGL gene promoter: a potential link between osteoblastogenesis and osteoclastogenesis. Bone 1998 23 (Suppl 1) S149 (Abstract no. 1003).
    • (1998) Bone , vol.23 , Issue.SUPPL. 1
    • O'Brien, C.A.1    Farrar, N.C.2    Manolagas, S.C.3
  • 50
    • 0032573550 scopus 로고    scopus 로고
    • Potential role of cbfa1, an essential transcriptional factor for osteoblast differentiation, in osteoclastogenesis: Regulation of mRNA expression of osteoclast differentiation factor (ODF)
    • Gao Y-H, Shinki T, Yuase T, Kataoka-Enomoto H, Komori T, Suda T et al. Potential role of cbfa1, an essential transcriptional factor for osteoblast differentiation, in osteoclastogenesis: Regulation of mRNA expression of osteoclast differentiation factor (ODF). Biochemical and Biophysical Research Communications 1998 252 697-702.
    • (1998) Biochemical and Biophysical Research Communications , vol.252 , pp. 697-702
    • Gao, Y.-H.1    Shinki, T.2    Yuase, T.3    Kataoka-Enomoto, H.4    Komori, T.5    Suda, T.6
  • 51
    • 0033611467 scopus 로고    scopus 로고
    • OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
    • Kong Y-Y, Yoshida H, Sarosi I, Tan H-L, Timms E, Capparelli C et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999 397 315-323.
    • (1999) Nature , vol.397 , pp. 315-323
    • Kong, Y.-Y.1    Yoshida, H.2    Sarosi, I.3    Tan, H.-L.4    Timms, E.5    Capparelli, C.6
  • 52
    • 0031765480 scopus 로고    scopus 로고
    • A combination of osteoclast differentiation factor and macrophage-colony stimulating factor is sufficient for both human and mouse osteoclast formation in vitro
    • Quinn JMW, Elliott J, Gillespie MT & Martin TJ. A combination of osteoclast differentiation factor and macrophage-colony stimulating factor is sufficient for both human and mouse osteoclast formation in vitro. Endocrinology 1998 139 4424-4427.
    • (1998) Endocrinology , vol.139 , pp. 4424-4427
    • Quinn, J.M.W.1    Elliott, J.2    Gillespie, M.T.3    Martin, T.J.4
  • 54
    • 0008171364 scopus 로고    scopus 로고
    • Osteoblasts/stromal cells activate osteoclast function through osteoclast differentiation factor (ODF)
    • Abstract no. T072
    • Udagawa N, Takahashi N, Matsuzaki K, Jimi E, Tsurukai T, Itoh K et al. Osteoblasts/stromal cells activate osteoclast function through osteoclast differentiation factor (ODF). Bone 1998 23 (Suppl 1) S220 (Abstract no. T072).
    • (1998) Bone , vol.23 , Issue.SUPPL. 1
    • Udagawa, N.1    Takahashi, N.2    Matsuzaki, K.3    Jimi, E.4    Tsurukai, T.5    Itoh, K.6
  • 55
    • 0004935244 scopus 로고    scopus 로고
    • Osteoclast differentiation factor (ODF) induces fusion, survival and activation of osteoclasts
    • Abstract no. T079
    • Jimi E, Akiyama S, Tsurukai T, Kobayashi K, Takahashi N, Udagawa N et al. Osteoclast differentiation factor (ODF) induces fusion, survival and activation of osteoclasts. Bone 1998 23 (Suppl 1) S222 (Abstract no. T079).
    • (1998) Bone , vol.23 , Issue.SUPPL. 1
    • Jimi, E.1    Akiyama, S.2    Tsurukai, T.3    Kobayashi, K.4    Takahashi, N.5    Udagawa, N.6
  • 56
    • 0031439265 scopus 로고    scopus 로고
    • TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor
    • Wong BR, Josien R, Young Lee S, Sauter B, Li H-L, Steinman RM et al. TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor. Journal of Experimental Medicine 1997 186 2075-2080.
    • (1997) Journal of Experimental Medicine , vol.186 , pp. 2075-2080
    • Wong, B.R.1    Josien, R.2    Young Lee, S.3    Sauter, B.4    Li, H.-L.5    Steinman, R.M.6
  • 61
    • 0032530455 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor-associated factors (TRAFs) - A family of adapter proteins that regulates life and death
    • Arch RH, Gedrich RW & Thompson CB. Tumor necrosis factor receptor-associated factors (TRAFs) - a family of adapter proteins that regulates life and death. Genes and Development 1998 12 2821-2830.
    • (1998) Genes and Development , vol.12 , pp. 2821-2830
    • Arch, R.H.1    Gedrich, R.W.2    Thompson, C.B.3
  • 62
    • 0032545465 scopus 로고    scopus 로고
    • The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanism of receptor activator of NF-κB, a member of the TNFR superfamily
    • Galibert L, Tometsko ME, Anderson DM, Cosman D & Dougall WC. The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanism of receptor activator of NF-κB, a member of the TNFR superfamily. Journal of Biological Chemistry 1998 273 34120-34127.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 34120-34127
    • Galibert, L.1    Tometsko, M.E.2    Anderson, D.M.3    Cosman, D.4    Dougall, W.C.5
  • 63
    • 0032544710 scopus 로고    scopus 로고
    • An intact zinc finger is required for tumor necrosis factor receptor-associated factor-mediated nuclear factor-κB activation but is dispensible for c-Jun N-terminal kinase signaling
    • Dadgostar H & Cheng G. An intact zinc finger is required for tumor necrosis factor receptor-associated factor-mediated nuclear factor-κB activation but is dispensible for c-Jun N-terminal kinase signaling. Journal of Biological Chemistry 1998 273 24775-24780.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 24775-24780
    • Dadgostar, H.1    Cheng, G.2
  • 64
    • 0032508414 scopus 로고    scopus 로고
    • NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and C-IAP2 to suppress caspase-8 activation
    • Wang C-Y, Mayo MW, Korneluk RG, Goeddel DV & Baldwin AS. NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and C-IAP2 to suppress caspase-8 activation. Science 1998 281 1680-1683.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.-Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin, A.S.5
  • 65
    • 0033561039 scopus 로고    scopus 로고
    • TRAF6-deficiency results in osteopetrosis and defective interleukin-1, CD40 and LPS signaling
    • Lomaga MA, Yeh W-C, Sarosi I, Duncan GS, Furlonger C, Ho A et al. TRAF6-deficiency results in osteopetrosis and defective interleukin-1, CD40 and LPS signaling. Genes and Development 1999 13 1015-1024.
    • (1999) Genes and Development , vol.13 , pp. 1015-1024
    • Lomaga, M.A.1    Yeh, W.-C.2    Sarosi, I.3    Duncan, G.S.4    Furlonger, C.5    Ho, A.6
  • 66
    • 0013051937 scopus 로고    scopus 로고
    • Mechanisms by which NF-κB regulates osteoclast numbers
    • Abstract no. 1172
    • Hing L, Carlson L, Siebenlist U & Boyce BF. Mechanisms by which NF-κB regulates osteoclast numbers. Bone 1998 23 (Suppl 1) S190 (Abstract no. 1172).
    • (1998) Bone , vol.23 , Issue.SUPPL. 1
    • Hing, L.1    Carlson, L.2    Siebenlist, U.3    Boyce, B.F.4
  • 67
    • 0031955217 scopus 로고    scopus 로고
    • A unitary model for involutional osteoporosis: Estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men
    • Riggs BL, Khosla S & Melton LJ. A unitary model for involutional osteoporosis: Estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. Journal of Bone and Mineral Research 1998 13 763-773.
    • (1998) Journal of Bone and Mineral Research , vol.13 , pp. 763-773
    • Riggs, B.L.1    Khosla, S.2    Melton, L.J.3
  • 68
    • 0025838316 scopus 로고
    • Modulation of transforming growth factor-β production in normal human osteoblast-like cells by 17β-estradiol and parathyroid hormone
    • Oursler MJ, Cortese C, Keeting PE, Anderson MA, Bonde SK, Riggs BL et al. Modulation of transforming growth factor-β production in normal human osteoblast-like cells by 17β-estradiol and parathyroid hormone. Endocrinology 1991 129 3313-3320.
    • (1991) Endocrinology , vol.129 , pp. 3313-3320
    • Oursler, M.J.1    Cortese, C.2    Keeting, P.E.3    Anderson, M.A.4    Bonde, S.K.5    Riggs, B.L.6
  • 69
    • 0029798819 scopus 로고    scopus 로고
    • Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-beta
    • Hughes DE, Dai A, Tiffee JC, Li HH & Mundy GR. Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-beta. Nature Medicine 1997 2 1132-1136.
    • (1997) Nature Medicine , vol.2 , pp. 1132-1136
    • Hughes, D.E.1    Dai, A.2    Tiffee, J.C.3    Li, H.H.4    Mundy, G.R.5
  • 70
    • 0033026628 scopus 로고    scopus 로고
    • Immunological characterization of circulating osteoprotegerin/osteoclastogenesis inhibitory factor: Increased serum concentrations in postmenopausal women with osteoporosis
    • Yano K, Tsuda E, Washida N, Kobayashi F, Goto M, Harada A et al. Immunological characterization of circulating osteoprotegerin/osteoclastogenesis inhibitory factor: Increased serum concentrations in postmenopausal women with osteoporosis. Journal of Bone and Mineral Research 1999 14 518-527.
    • (1999) Journal of Bone and Mineral Research , vol.14 , pp. 518-527
    • Yano, K.1    Tsuda, E.2    Washida, N.3    Kobayashi, F.4    Goto, M.5    Harada, A.6
  • 71
    • 0001028160 scopus 로고    scopus 로고
    • Osteoprotegerin serum levels in healthy volunteers
    • Abstract no. T411
    • Arrighi HM, Hsieh A, Wong H, Khoo H, Reyes A, Asbury D et al. Osteoprotegerin serum levels in healthy volunteers. Bone 1998 23 (Suppl 1) S298 (Abstract no. T411).
    • (1998) Bone , vol.23 , Issue.SUPPL. 1
    • Arrighi, H.M.1    Hsieh, A.2    Wong, H.3    Khoo, H.4    Reyes, A.5    Asbury, D.6
  • 73
    • 0029802660 scopus 로고    scopus 로고
    • Estrogen deficiency increases the ability of stromal cells to support murine osteoclastogenesis via an interleukin-1- and tumor necrosis factor-mediated stimulation of macrophage colony-stimulating factor production
    • Kimble RB, Srivastava S, Ross FP, Matayoshi A & Pacifici R. Estrogen deficiency increases the ability of stromal cells to support murine osteoclastogenesis via an interleukin-1- and tumor necrosis factor-mediated stimulation of macrophage colony-stimulating factor production. Journal of Biological Chemistry 1996 46 28890-28897.
    • (1996) Journal of Biological Chemistry , vol.46 , pp. 28890-28897
    • Kimble, R.B.1    Srivastava, S.2    Ross, F.P.3    Matayoshi, A.4    Pacifici, R.5
  • 74
    • 0025101215 scopus 로고
    • Glucocorticoid-induced osteoporosis: Pathogenesis and management
    • Lukert B & Raisz LG. Glucocorticoid-induced osteoporosis: pathogenesis and management. Annals of Internal Medicine 1990 112 352-364.
    • (1990) Annals of Internal Medicine , vol.112 , pp. 352-364
    • Lukert, B.1    Raisz, L.G.2
  • 75
    • 0030763592 scopus 로고    scopus 로고
    • Glucocorticoid osteoporosis - Mechanisms and management
    • Reid IR. Glucocorticoid osteoporosis - mechanisms and management. European Journal of Endocrinology 1997 137 209-217.
    • (1997) European Journal of Endocrinology , vol.137 , pp. 209-217
    • Reid, I.R.1
  • 77
    • 0029821686 scopus 로고    scopus 로고
    • Mechanisms of glucocorticoid action in bone: Implications to glucocorticoid-induced osteoporosis
    • Canalis E. Mechanisms of glucocorticoid action in bone: Implications to glucocorticoid-induced osteoporosis. Journal of Clinical Endocrinology and Metabolism 1996 81 3441-3447.
    • (1996) Journal of Clinical Endocrinology and Metabolism , vol.81 , pp. 3441-3447
    • Canalis, E.1
  • 78
    • 0029759430 scopus 로고    scopus 로고
    • Stimulation of neonatal mouse calvarial bone resorption by the glucocorticoids hydrocortisone and dexamethasone
    • Conaway HH, Grogorie D & Lerner UH. Stimulation of neonatal mouse calvarial bone resorption by the glucocorticoids hydrocortisone and dexamethasone. Journal of Bone and Mineral Research 1996 11 1419-1429.
    • (1996) Journal of Bone and Mineral Research , vol.11 , pp. 1419-1429
    • Conaway, H.H.1    Grogorie, D.2    Lerner, U.H.3
  • 81
    • 15644372741 scopus 로고    scopus 로고
    • Alterations of bone turnover and bone mass at different skeletal sites due to pure glucocorticoid excess: Study in eumenorrheic patients with Cushing's syndrome
    • Chiodini I, Carnevale V, Torlontano M, Fusilli S, Gugglielmi G, Pileri M et al. Alterations of bone turnover and bone mass at different skeletal sites due to pure glucocorticoid excess: study in eumenorrheic patients with Cushing's syndrome. Journal of Clinical Endocrinology and Metabolism 1998 83 1863-1867.
    • (1998) Journal of Clinical Endocrinology and Metabolism , vol.83 , pp. 1863-1867
    • Chiodini, I.1    Carnevale, V.2    Torlontano, M.3    Fusilli, S.4    Gugglielmi, G.5    Pileri, M.6
  • 82
    • 0013946259 scopus 로고
    • Quantitative microradiographic study of bone remodeling in Cushing's syndrome
    • Riggs BL, Jowsey J & Kelly PJ. Quantitative microradiographic study of bone remodeling in Cushing's syndrome. Metabolism 1966 15 773-780.
    • (1966) Metabolism , vol.15 , pp. 773-780
    • Riggs, B.L.1    Jowsey, J.2    Kelly, P.J.3
  • 83
    • 0000107804 scopus 로고    scopus 로고
    • Bone histomorphometry in glucocorticoid-induced osteoporosis
    • Dempster D. Bone histomorphometry in glucocorticoid-induced osteoporosis. Journal of Bone and Mineral Research 1998 13 137-141.
    • (1998) Journal of Bone and Mineral Research , vol.13 , pp. 137-141
    • Dempster, D.1
  • 84
    • 0030048510 scopus 로고    scopus 로고
    • Recent developments on the understanding of the pathophysiology of osteopetrosis
    • Felix R, Hofstetter W & Cecchini MG. Recent developments on the understanding of the pathophysiology of osteopetrosis. European Journal of Endocrinology 1996 134 143-156.
    • (1996) European Journal of Endocrinology , vol.134 , pp. 143-156
    • Felix, R.1    Hofstetter, W.2    Cecchini, M.G.3
  • 86
    • 0025332897 scopus 로고
    • The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene
    • Yoshida H, Hayashi S, Kunisada T, Ogawa M, Nishikawa S, Okamura H et al. The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature 1990 345 442-444.
    • (1990) Nature , vol.345 , pp. 442-444
    • Yoshida, H.1    Hayashi, S.2    Kunisada, T.3    Ogawa, M.4    Nishikawa, S.5    Okamura, H.6
  • 87
    • 0004556472 scopus 로고    scopus 로고
    • Activated T cells are capable of inducing osteoclast formation: A mechanism for rheumatoid arthritis
    • Abstract no. T046
    • Horwood NJ, Kartsgiannis V, Lam MHC, Romas E, Quinn JMW, Martin TJ et al. Activated T cells are capable of inducing osteoclast formation: a mechanism for rheumatoid arthritis. Bone 1998 23 (Suppl 1) S214 (Abstract no. T046).
    • (1998) Bone , vol.23 , Issue.SUPPL. 1
    • Horwood, N.J.1    Kartsgiannis, V.2    Lam, M.H.C.3    Romas, E.4    Quinn, J.M.W.5    Martin, T.J.6
  • 88
    • 0001295334 scopus 로고    scopus 로고
    • Presence of osteoclastogenesis inhibitory factor/osteoprotegerin in synovial fluids from patients with rheumatoid arthritis
    • Abstract no. 1727
    • Kotake S, Udagawa N, Takahashi N, Yano K, Tsuda E, Higashio K et al. Presence of osteoclastogenesis inhibitory factor/osteoprotegerin in synovial fluids from patients with rheumatoid arthritis. Arthritis and Rheumatism 1998 41 (Suppl) S320 (Abstract no. 1727).
    • (1998) Arthritis and Rheumatism , vol.41 , Issue.SUPPL.
    • Kotake, S.1    Udagawa, N.2    Takahashi, N.3    Yano, K.4    Tsuda, E.5    Higashio, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.