LXR and TSPO as new therapeutic targets to increase the levels of neuroactive steroids in the central nervous system of diabetic animals

Neurochemistry International

Volumn 60, Issue 6, 2012, Pages 616-621

  Mitro, Nico ^a   Cermenati, Gaia ^a   Giatti, Silvia ^a   Abbiati, Federico ^a   Pesaresi, Marzia ^a   Calabrese, Donato ^a   Garcia Segura, Luis Miguel ^b   Caruso, Donatella ^a   Melcangi, Roberto C ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b INSTITUTO CAJAL   (Spain)

Author keywords

Central nervous system; Cholesterol; Liquid chromatography tandem mass spectrometry; Rat; Steroid level; Streptozotocin

Indexed keywords

17ALPHA ESTRADIOL; 20ALPHA DIHYDROPROGESTERONE; 3 [3 [[2 CHLORO 3 (TRIFLUOROMETHYL)BENZYL](2 DIPHENYLETHYL)AMINO]PROPOXY]PHENYLACETIC ACID; 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 3BETA HYDROXY 5ALPHA PREGNAN 20 ONE; 4' CHLORODIAZEPAM; 5ALPHA PREGNANE 3,20 DIONE; ANDROSTANEDIOL; ANDROSTANOLONE; CARRIER PROTEIN; ESTRADIOL; ESTROGEN; LIVER X RECEPTOR; MYELIN BASIC PROTEIN; PRASTERONE; PREGNENOLONE; PROGESTERONE; STEROID; TESTOSTERONE; TETRAHYDROPROGESTERONE; TRANSLOCATOR PROTEIN 18 KDA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CONTROLLED STUDY; DRUG TARGETING; MALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; RAT; SPINAL CORD; STREPTOZOCIN DIABETES;

ANIMALS; BENZODIAZEPINONES; CARRIER PROTEINS; DIABETES COMPLICATIONS; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; MALE; NERVE DEGENERATION; ORPHAN NUCLEAR RECEPTORS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; STEROIDS; UP-REGULATION;

ANIMALIA; RATTUS;

EID: 84860448923     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2012.02.025     Document Type: Article

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