메뉴 건너뛰기




Volumn 1514, Issue , 2013, Pages 98-106

Progesterone-induced neuroprotection: Factors that may predict therapeutic efficacy

Author keywords

Medroxyprogesterone acetate; Neuroprotection; Progesterone; Therapeutic window

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; BRAIN DERIVED NEUROTROPHIC FACTOR; GESTAGEN; MEDROXYPROGESTERONE ACETATE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; NEUROTROPHIN; PROGESTERONE; PROGESTERONE RECEPTOR; STEROID HORMONE;

EID: 84878518152     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.01.027     Document Type: Review
Times cited : (40)

References (99)
  • 1
    • 0031016850 scopus 로고    scopus 로고
    • Medroxyprogesterone acetate antagonizes inhibitory effects of conjugated equine estrogens on coronary artery atherosclerosis
    • M.R. Adams, T.C. Register, D.L. Golden, J.D. Wagner, and J.K. Williams Medroxyprogesterone acetate antagonizes inhibitory effects of conjugated equine estrogens on coronary artery atherosclerosis Arterioscler. Thromb. Vasc. Biol. 17 1997 217 221
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 217-221
    • Adams, M.R.1    Register, T.C.2    Golden, D.L.3    Wagner, J.D.4    Williams, J.K.5
  • 2
    • 33750909432 scopus 로고    scopus 로고
    • Mechanism of progesterone neuroprotection of rat cerebellar Purkinje cells following oxygen-glucose deprivation
    • A. Ardeshiri, M.H. Kelley, I.P. Korner, P.D. Hurn, and P.S. Herson Mechanism of progesterone neuroprotection of rat cerebellar Purkinje cells following oxygen-glucose deprivation Eur. J. Neurosci. 24 2006 2567 2574
    • (2006) Eur. J. Neurosci. , vol.24 , pp. 2567-2574
    • Ardeshiri, A.1    Kelley, M.H.2    Korner, I.P.3    Hurn, P.D.4    Herson, P.S.5
  • 3
    • 0023629050 scopus 로고
    • Hormonal state affects recovery from frontal cortex lesions in adult female rats
    • M.J. Attella, A. Nattinville, and D.G. Stein Hormonal state affects recovery from frontal cortex lesions in adult female rats Behav. Neural. Biol. 48 1987 352 367
    • (1987) Behav. Neural. Biol. , vol.48 , pp. 352-367
    • Attella, M.J.1    Nattinville, A.2    Stein, D.G.3
  • 4
    • 54349088961 scopus 로고    scopus 로고
    • Nonclassical mechanisms of progesterone action in the brain: I. Protein kinase C activation in the hypothalamus of female rats
    • B. Balasubramanian, W. Portillo, A. Reyna, J.Z. Chen, A.N. Moore, P.K. Dash, and S.K. Mani Nonclassical mechanisms of progesterone action in the brain: I. Protein kinase C activation in the hypothalamus of female rats Endocrinology 149 2008 5509 5517
    • (2008) Endocrinology , vol.149 , pp. 5509-5517
    • Balasubramanian, B.1    Portillo, W.2    Reyna, A.3    Chen, J.Z.4    Moore, A.N.5    Dash, P.K.6    Mani, S.K.7
  • 5
    • 54349123069 scopus 로고    scopus 로고
    • Nonclassical mechanisms of progesterone action in the brain: II. Role of calmodulin-dependent protein kinase II in progesterone-mediated signaling in the hypothalamus of female rats
    • B. Balasubramanian, W. Portillo, A. Reyna, J.Z. Chen, A.N. Moore, P.K. Dash, and S.K. Mani Nonclassical mechanisms of progesterone action in the brain: II. Role of calmodulin-dependent protein kinase II in progesterone-mediated signaling in the hypothalamus of female rats Endocrinology 149 2008 5518 5526
    • (2008) Endocrinology , vol.149 , pp. 5518-5526
    • Balasubramanian, B.1    Portillo, W.2    Reyna, A.3    Chen, J.Z.4    Moore, A.N.5    Dash, P.K.6    Mani, S.K.7
  • 6
    • 0028971169 scopus 로고
    • 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro
    • C. Behl, M. Widmann, T. Trapp, and F. Holsboer 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro Biochem. Biophys. Res. Commun. 216 1995 473 482
    • (1995) Biochem. Biophys. Res. Commun. , vol.216 , pp. 473-482
    • Behl, C.1    Widmann, M.2    Trapp, T.3    Holsboer, F.4
  • 8
    • 77952549112 scopus 로고    scopus 로고
    • The beneficial effects of estradiol on attentional processes are dependent on timing of treatment initiation following ovariectomy in middle-aged rats
    • J. Bohacek, and J.M. Daniel The beneficial effects of estradiol on attentional processes are dependent on timing of treatment initiation following ovariectomy in middle-aged rats Psychoneuroendocrinology 35 2010 694 705
    • (2010) Psychoneuroendocrinology , vol.35 , pp. 694-705
    • Bohacek, J.1    Daniel, J.M.2
  • 9
    • 47149112183 scopus 로고    scopus 로고
    • Two different molecular mechanisms underlying progesterone neuroprotection against ischemic brain damage
    • W. Cai, Y. Zhu, K. Furuya, Z. Li, M. Sokabe, and L. Chen Two different molecular mechanisms underlying progesterone neuroprotection against ischemic brain damage Neuropharmacology 55 2008 127 138
    • (2008) Neuropharmacology , vol.55 , pp. 127-138
    • Cai, W.1    Zhu, Y.2    Furuya, K.3    Li, Z.4    Sokabe, M.5    Chen, L.6
  • 10
    • 0036146341 scopus 로고    scopus 로고
    • Neuroprotective effects of progesterone on damage elicited by acute global cerebral ischemia in neurons of the caudate nucleus
    • M. Cervantes, M.D. Gonzalez-Vidal, R. Ruelas, A. Escobar, and G. Morali Neuroprotective effects of progesterone on damage elicited by acute global cerebral ischemia in neurons of the caudate nucleus Arch. Med. Res. 33 2002 6 14
    • (2002) Arch. Med. Res. , vol.33 , pp. 6-14
    • Cervantes, M.1    Gonzalez-Vidal, M.D.2    Ruelas, R.3    Escobar, A.4    Morali, G.5
  • 11
    • 0032724682 scopus 로고    scopus 로고
    • Neuroprotective effects of progesterone after transient middle cerebral artery occlusion in rat
    • J. Chen, M. Chopp, and Y. Li Neuroprotective effects of progesterone after transient middle cerebral artery occlusion in rat J. Neurol. Sci. 171 1999 24 30
    • (1999) J. Neurol. Sci. , vol.171 , pp. 24-30
    • Chen, J.1    Chopp, M.2    Li, Y.3
  • 12
    • 0742272125 scopus 로고    scopus 로고
    • Reduced progesterone metabolites protect rat hippocampal neurones from kainic acid excitotoxicity in vivo
    • I. Ciriza, I. Azcoitia, and L.M. Garcia-Segura Reduced progesterone metabolites protect rat hippocampal neurones from kainic acid excitotoxicity in vivo J. Neuroendocrinol. 16 2004 58 63
    • (2004) J. Neuroendocrinol. , vol.16 , pp. 58-63
    • Ciriza, I.1    Azcoitia, I.2    Garcia-Segura, L.M.3
  • 13
    • 0022349617 scopus 로고
    • Effect of progesterone upon adenylate cyclase activity and cAMP levels on brain areas
    • M.L. Collado, G. Rodriguez-Manzo, and M.L. Cruz Effect of progesterone upon adenylate cyclase activity and cAMP levels on brain areas Pharmacol. Biochem. Behav. 23 1985 501 504
    • (1985) Pharmacol. Biochem. Behav. , vol.23 , pp. 501-504
    • Collado, M.L.1    Rodriguez-Manzo, G.2    Cruz, M.L.3
  • 14
    • 0033669231 scopus 로고    scopus 로고
    • Progesterone receptors in reproduction: Functional impact of the A and B isoforms
    • O.M. Conneely, and J.P. Lydon Progesterone receptors in reproduction: functional impact of the A and B isoforms Steroids 65 2000 571 577
    • (2000) Steroids , vol.65 , pp. 571-577
    • Conneely, O.M.1    Lydon, J.P.2
  • 15
    • 77956180117 scopus 로고    scopus 로고
    • The critical period hypothesis of estrogen effects on cognition: Insights from basic research
    • J.M. Daniel, and J. Bohacek The critical period hypothesis of estrogen effects on cognition: insights from basic research Biochim. Biophys. Acta. 1800 2010 1068 1076
    • (2010) Biochim. Biophys. Acta. , vol.1800 , pp. 1068-1076
    • Daniel, J.M.1    Bohacek, J.2
  • 16
    • 0026662235 scopus 로고
    • GABA-active steroids: Endogenous modulators of GABA-gated chloride ion conductance
    • S.I. Deutsch, J. Mastropaolo, and A. Hitri GABA-active steroids: endogenous modulators of GABA-gated chloride ion conductance Clin. Neuropharmacol. 15 1992 352 364
    • (1992) Clin. Neuropharmacol. , vol.15 , pp. 352-364
    • Deutsch, S.I.1    Mastropaolo, J.2    Hitri, A.3
  • 17
    • 0347418151 scopus 로고    scopus 로고
    • Allopregnanolone and progesterone decrease cell death and cognitive deficits after a contusion of the rat pre-frontal cortex
    • M. Djebaili, S.W. Hoffman, and D.G. Stein Allopregnanolone and progesterone decrease cell death and cognitive deficits after a contusion of the rat pre-frontal cortex Neuroscience 123 2004 349 359
    • (2004) Neuroscience , vol.123 , pp. 349-359
    • Djebaili, M.1    Hoffman, S.W.2    Stein, D.G.3
  • 18
    • 7044249573 scopus 로고    scopus 로고
    • Reproductive events modify the effects of estrogen replacement therapy on cognition in healthy postmenopausal women
    • J. Dunkin, N. Rasgon, K. Wagner-Steh, S. David, L. Altshuler, and A. Rapkin Reproductive events modify the effects of estrogen replacement therapy on cognition in healthy postmenopausal women Psychoneuroendocrinology 30 2005 284 296
    • (2005) Psychoneuroendocrinology , vol.30 , pp. 284-296
    • Dunkin, J.1    Rasgon, N.2    Wagner-Steh, K.3    David, S.4    Altshuler, L.5    Rapkin, A.6
  • 20
    • 0023013514 scopus 로고
    • The role of hormones in the etiology and prevention of endometrial cancer
    • R.D. Gambrell Jr. The role of hormones in the etiology and prevention of endometrial cancer Clin. Obstet. Gynaecol. 13 1986 695 723
    • (1986) Clin. Obstet. Gynaecol. , vol.13 , pp. 695-723
    • Gambrell, Jr.R.D.1
  • 21
    • 0037056029 scopus 로고    scopus 로고
    • Effects of long-term hormone replacement and of tibolone on choline acetyltransferase and acetylcholinesterase activities in the brains of ovariectomized, cynomologus monkeys
    • R.B. Gibbs, D. Nelson, M.S. Anthony, and T.B. Clarkson Effects of long-term hormone replacement and of tibolone on choline acetyltransferase and acetylcholinesterase activities in the brains of ovariectomized, cynomologus monkeys Neuroscience 113 2002 907 914
    • (2002) Neuroscience , vol.113 , pp. 907-914
    • Gibbs, R.B.1    Nelson, D.2    Anthony, M.S.3    Clarkson, T.B.4
  • 22
    • 79959711271 scopus 로고    scopus 로고
    • Progesterone is neuroprotective following cerebral ischaemia in reproductively ageing female mice
    • C.L. Gibson, B. Coomber, and S.P. Murphy Progesterone is neuroprotective following cerebral ischaemia in reproductively ageing female mice Brain 134 2011 2125 2133
    • (2011) Brain , vol.134 , pp. 2125-2133
    • Gibson, C.L.1    Coomber, B.2    Murphy, S.P.3
  • 27
    • 0029924284 scopus 로고    scopus 로고
    • Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neurons
    • Y. Goodman, A.J. Bruce, B. Cheng, and M.P. Mattson Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neurons J. Neurochem. 66 1996 1836 1844
    • (1996) J. Neurochem. , vol.66 , pp. 1836-1844
    • Goodman, Y.1    Bruce, A.J.2    Cheng, B.3    Mattson, M.P.4
  • 28
    • 0025013613 scopus 로고
    • Down-regulation of androgen receptor by progestins and interference with estrogenic or androgenic stimulation of mammary carcinoma cell growth
    • R. Hackenberg, J. Hofmann, G. Wolff, F. Holzel, and K.D. Schulz Down-regulation of androgen receptor by progestins and interference with estrogenic or androgenic stimulation of mammary carcinoma cell growth J. Cancer Res. Clin. Oncol. 116 1990 492 498
    • (1990) J. Cancer Res. Clin. Oncol. , vol.116 , pp. 492-498
    • Hackenberg, R.1    Hofmann, J.2    Wolff, G.3    Holzel, F.4    Schulz, K.D.5
  • 29
    • 4544282704 scopus 로고    scopus 로고
    • Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury
    • J. He, C.O. Evans, S.W. Hoffman, N.M. Oyesiku, and D.G. Stein Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury Exp. Neurol. 189 2004 404 412
    • (2004) Exp. Neurol. , vol.189 , pp. 404-412
    • He, J.1    Evans, C.O.2    Hoffman, S.W.3    Oyesiku, N.M.4    Stein, D.G.5
  • 30
    • 1942474435 scopus 로고    scopus 로고
    • Allopregnanolone, a progesterone metabolite, enhances behavioral recovery and decreases neuronal loss after traumatic brain injury
    • J. He, S.W. Hoffman, and D.G. Stein Allopregnanolone, a progesterone metabolite, enhances behavioral recovery and decreases neuronal loss after traumatic brain injury Restor. Neurol. Neurosci. 22 2004 19 31
    • (2004) Restor. Neurol. Neurosci. , vol.22 , pp. 19-31
    • He, J.1    Hoffman, S.W.2    Stein, D.G.3
  • 31
    • 33644499808 scopus 로고    scopus 로고
    • Estrogen-containing hormone therapy and Alzheimer's disease risk: Understanding discrepant inferences from observational and experimental research
    • V.W. Henderson Estrogen-containing hormone therapy and Alzheimer's disease risk: understanding discrepant inferences from observational and experimental research Neuroscience 138 2006 1031 1039
    • (2006) Neuroscience , vol.138 , pp. 1031-1039
    • Henderson, V.W.1
  • 32
    • 0029784421 scopus 로고    scopus 로고
    • Progestins
    • suppl
    • E. Hirvonen Progestins Maturitas 23 1996 S13 S18 suppl
    • (1996) Maturitas , vol.23
    • Hirvonen, E.1
  • 33
    • 0037757590 scopus 로고    scopus 로고
    • Ovarian steroid modulation of seizure severity and hippocampal cell death after kainic acid treatment
    • G.E. Hoffman, N. Moore, G. Fiskum, and A.Z. Murphy Ovarian steroid modulation of seizure severity and hippocampal cell death after kainic acid treatment Exp. Neurol. 182 2003 124 134
    • (2003) Exp. Neurol. , vol.182 , pp. 124-134
    • Hoffman, G.E.1    Moore, N.2    Fiskum, G.3    Murphy, A.Z.4
  • 35
    • 0030607198 scopus 로고    scopus 로고
    • Progesterone is neuroprotective after transient middle cerebral artery occlusion in male rats
    • N. Jiang, M. Chopp, D. Stein, and H. Feit Progesterone is neuroprotective after transient middle cerebral artery occlusion in male rats Brain Res. 735 1996 101 107
    • (1996) Brain Res. , vol.735 , pp. 101-107
    • Jiang, N.1    Chopp, M.2    Stein, D.3    Feit, H.4
  • 36
    • 67649664596 scopus 로고    scopus 로고
    • The differences in neuroprotective efficacy of progesterone and medroxyprogesterone acetate correlate with their effects on brain-derived neurotrophic factor expression
    • P.K. Jodhka, P. Kaur, W. Underwood, J.P. Lydon, and M. Singh The differences in neuroprotective efficacy of progesterone and medroxyprogesterone acetate correlate with their effects on brain-derived neurotrophic factor expression Endocrinology 150 2009 3162 3168
    • (2009) Endocrinology , vol.150 , pp. 3162-3168
    • Jodhka, P.K.1    Kaur, P.2    Underwood, W.3    Lydon, J.P.4    Singh, M.5
  • 38
    • 34547622839 scopus 로고    scopus 로고
    • Progesterone increases brain-derived neuroptrophic factor expression and protects against glutamate toxicity in a mitogen-activated protein kinase- and phosphoinositide-3 kinase-dependent manner in cerebral cortical explants
    • P. Kaur, P.K. Jodhka, W.A. Underwood, C.A. Bowles, N.C. de Fiebre, C.M. de Fiebre, and M. Singh Progesterone increases brain-derived neuroptrophic factor expression and protects against glutamate toxicity in a mitogen-activated protein kinase- and phosphoinositide-3 kinase-dependent manner in cerebral cortical explants J. Neurosci. Res. 85 2007 2441 2449
    • (2007) J. Neurosci. Res. , vol.85 , pp. 2441-2449
    • Kaur, P.1    Jodhka, P.K.2    Underwood, W.A.3    Bowles, C.A.4    De Fiebre, N.C.5    De Fiebre, C.M.6    Singh, M.7
  • 39
    • 0025068789 scopus 로고
    • Binding of progesterone to nerve cell membranes of rat brain using progesterone conjugated to 125I-bovine serum albumin as a ligand
    • F.C. Ke, and V.D. Ramirez Binding of progesterone to nerve cell membranes of rat brain using progesterone conjugated to 125I-bovine serum albumin as a ligand J. Neurochem. 54 1990 467 472
    • (1990) J. Neurochem. , vol.54 , pp. 467-472
    • Ke, F.C.1    Ramirez, V.D.2
  • 40
  • 41
    • 0033741196 scopus 로고    scopus 로고
    • A membrane-associated progesterone-binding protein, 25-Dx, is regulated by progesterone in brain regions involved in female reproductive behaviors
    • C.J. Krebs, E.D. Jarvis, J. Chan, J.P. Lydon, S. Ogawa, and D.W. Pfaff A membrane-associated progesterone-binding protein, 25-Dx, is regulated by progesterone in brain regions involved in female reproductive behaviors Proc. Natl. Acad. Sci. USA 97 2000 12816 12821
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 12816-12821
    • Krebs, C.J.1    Jarvis, E.D.2    Chan, J.3    Lydon, J.P.4    Ogawa, S.5    Pfaff, D.W.6
  • 42
    • 0034016139 scopus 로고    scopus 로고
    • Neuroprotective effect of postischemic administration of progesterone in spontaneously hypertensive rats with focal cerebral ischemia
    • Y. Kumon, S.C. Kim, P. Tompkins, A. Stevens, S. Sakaki, and C.M. Loftus Neuroprotective effect of postischemic administration of progesterone in spontaneously hypertensive rats with focal cerebral ischemia J. Neurosurg. 92 2000 848 852
    • (2000) J. Neurosurg. , vol.92 , pp. 848-852
    • Kumon, Y.1    Kim, S.C.2    Tompkins, P.3    Stevens, A.4    Sakaki, S.5    Loftus, C.M.6
  • 43
    • 17044361906 scopus 로고    scopus 로고
    • Effects of combined oral conjugated estrogens and medroxyprogesterone acetate on brain infarction size after experimental stroke in rat
    • M.T. Littleton-Kearney, J.A. Klaus, and P.D. Hurn Effects of combined oral conjugated estrogens and medroxyprogesterone acetate on brain infarction size after experimental stroke in rat J. Cereb. Blood Flow Metab. 25 2005 421 426
    • (2005) J. Cereb. Blood Flow Metab. , vol.25 , pp. 421-426
    • Littleton-Kearney, M.T.1    Klaus, J.A.2    Hurn, P.D.3
  • 45
    • 67649670455 scopus 로고    scopus 로고
    • Progesterone increases rat neural progenitor cell cycle gene expression and proliferation via extracellularly regulated kinase and progesterone receptor membrane components 1 and 2
    • L. Liu, J. Wang, L. Zhao, J. Nilsen, K. McClure, K. Wong, and R.D. Brinton Progesterone increases rat neural progenitor cell cycle gene expression and proliferation via extracellularly regulated kinase and progesterone receptor membrane components 1 and 2 Endocrinology 150 2009 3186 3196
    • (2009) Endocrinology , vol.150 , pp. 3186-3196
    • Liu, L.1    Wang, J.2    Zhao, L.3    Nilsen, J.4    McClure, K.5    Wong, K.6    Brinton, R.D.7
  • 46
    • 0032192065 scopus 로고    scopus 로고
    • Estradiol enhances learning and memory in a spatial memory task and effects levels of monoaminergic neurotransmitters [In Process Citation]
    • V.N. Luine, S.T. Richards, V.Y. Wu, and K.D. Beck Estradiol enhances learning and memory in a spatial memory task and effects levels of monoaminergic neurotransmitters [In Process Citation] Horm. Behav. 34 1998 149 162
    • (1998) Horm. Behav. , vol.34 , pp. 149-162
    • Luine, V.N.1    Richards, S.T.2    Wu, V.Y.3    Beck, K.D.4
  • 47
    • 0019514476 scopus 로고
    • Neuronal plasticity in the deafferented hypothalamic arcuate nucleus of adult female rats and its enhancement by treatment with estrogen
    • A. Matsumoto, and Y. Arai Neuronal plasticity in the deafferented hypothalamic arcuate nucleus of adult female rats and its enhancement by treatment with estrogen J. Comp. Neurol. 197 1981 197 205
    • (1981) J. Comp. Neurol. , vol.197 , pp. 197-205
    • Matsumoto, A.1    Arai, Y.2
  • 48
    • 33846620383 scopus 로고    scopus 로고
    • Neuro(active)steroids actions at the neuromodulatory sigma1 (sigma1) receptor: Biochemical and physiological evidences, consequences in neuroprotection
    • T. Maurice, C. Gregoire, and J. Espallergues Neuro(active)steroids actions at the neuromodulatory sigma1 (sigma1) receptor: biochemical and physiological evidences, consequences in neuroprotection Pharmacol. Biochem. Behav. 84 2006 581 597
    • (2006) Pharmacol. Biochem. Behav. , vol.84 , pp. 581-597
    • Maurice, T.1    Gregoire, C.2    Espallergues, J.3
  • 49
    • 0032949983 scopus 로고    scopus 로고
    • Activation of p42 mitogen-activated protein kinase by arachidonic acid and trans-1-amino-cyclopentyl-1,3-dicarboxylate impacts on long-term potentiation in the dentate gyrus in the rat: Analysis of age-related changes
    • B. McGahon, C. Maguire, A. Kelly, and M.A. Lynch Activation of p42 mitogen-activated protein kinase by arachidonic acid and trans-1-amino- cyclopentyl-1,3-dicarboxylate impacts on long-term potentiation in the dentate gyrus in the rat: analysis of age-related changes Neuroscience 90 1999 1167 1175
    • (1999) Neuroscience , vol.90 , pp. 1167-1175
    • McGahon, B.1    Maguire, C.2    Kelly, A.3    Lynch, M.A.4
  • 50
    • 20144368632 scopus 로고    scopus 로고
    • The membrane-associated progesterone-binding protein 25-Dx is expressed in brain regions involved in water homeostasis and is up-regulated after traumatic brain injury
    • D. Meffre, B. Delespierre, M. Gouezou, P. Leclerc, G.P. Vinson, M. Schumacher, D.G. Stein, and R. Guennoun The membrane-associated progesterone-binding protein 25-Dx is expressed in brain regions involved in water homeostasis and is up-regulated after traumatic brain injury J. Neurochem. 93 2005 1314 1326
    • (2005) J. Neurochem. , vol.93 , pp. 1314-1326
    • Meffre, D.1    Delespierre, B.2    Gouezou, M.3    Leclerc, P.4    Vinson, G.P.5    Schumacher, M.6    Stein, D.G.7    Guennoun, R.8
  • 51
    • 0029900104 scopus 로고    scopus 로고
    • Purification and partial sequencing of high-affinity progesterone-binding site(s) from porcine liver membranes
    • C. Meyer, R. Schmid, P.C. Scriba, and M. Wehling Purification and partial sequencing of high-affinity progesterone-binding site(s) from porcine liver membranes Eur. J. Biochem. 239 1996 726 731
    • (1996) Eur. J. Biochem. , vol.239 , pp. 726-731
    • Meyer, C.1    Schmid, R.2    Scriba, P.C.3    Wehling, M.4
  • 56
    • 0036141071 scopus 로고    scopus 로고
    • Impact of progestins on estrogen-induced neuroprotection: Synergy by progesterone and 19-norprogesterone and antagonism by medroxyprogesterone acetate
    • J. Nilsen, and R.D. Brinton Impact of progestins on estrogen-induced neuroprotection: synergy by progesterone and 19-norprogesterone and antagonism by medroxyprogesterone acetate Endocrinology 143 2002 205 212
    • (2002) Endocrinology , vol.143 , pp. 205-212
    • Nilsen, J.1    Brinton, R.D.2
  • 57
    • 0037035590 scopus 로고    scopus 로고
    • Impact of progestins on estradiol potentiation of the glutamate calcium response
    • J. Nilsen, and R.D. Brinton Impact of progestins on estradiol potentiation of the glutamate calcium response Neuroreport 13 2002 825 830
    • (2002) Neuroreport , vol.13 , pp. 825-830
    • Nilsen, J.1    Brinton, R.D.2
  • 58
    • 0042337371 scopus 로고    scopus 로고
    • Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling
    • J. Nilsen, and R.D. Brinton Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling Proc. Natl. Acad. Sci. USA 100 2003 10506 10511
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 10506-10511
    • Nilsen, J.1    Brinton, R.D.2
  • 59
    • 20444477493 scopus 로고    scopus 로고
    • Progesterone treatment inhibits the inflammatory agents that accompany traumatic brain injury
    • E.H. Pettus, D.W. Wright, D.G. Stein, and S.W. Hoffman Progesterone treatment inhibits the inflammatory agents that accompany traumatic brain injury Brain Res. 1049 2005 112 119
    • (2005) Brain Res. , vol.1049 , pp. 112-119
    • Pettus, E.H.1    Wright, D.W.2    Stein, D.G.3    Hoffman, S.W.4
  • 60
    • 40849141078 scopus 로고    scopus 로고
    • Prolonged ovarian hormone deprivation impairs the protective vascular actions of estrogen receptor alpha agonists
    • C. Pinna, A. Cignarella, P. Sanvito, V. Pelosi, and C. Bolego Prolonged ovarian hormone deprivation impairs the protective vascular actions of estrogen receptor alpha agonists Hypertension 51 2008 1210 1217
    • (2008) Hypertension , vol.51 , pp. 1210-1217
    • Pinna, C.1    Cignarella, A.2    Sanvito, P.3    Pelosi, V.4    Bolego, C.5
  • 61
    • 29144480051 scopus 로고    scopus 로고
    • Physiologic progesterone reduces mitochondrial dysfunction and hippocampal cell loss after traumatic brain injury in female rats
    • C.L. Robertson, A. Puskar, G.E. Hoffman, A.Z. Murphy, M. Saraswati, and G. Fiskum Physiologic progesterone reduces mitochondrial dysfunction and hippocampal cell loss after traumatic brain injury in female rats Exp. Neurol. 197 2006 235 243
    • (2006) Exp. Neurol. , vol.197 , pp. 235-243
    • Robertson, C.L.1    Puskar, A.2    Hoffman, G.E.3    Murphy, A.Z.4    Saraswati, M.5    Fiskum, G.6
  • 62
    • 0029878565 scopus 로고    scopus 로고
    • Progesterone rapidly decreases brain edema: Treatment delayed up to 24 h is still effective
    • R.L. Roof, R. Duvdevani, J.W. Heyburn, and D.G. Stein Progesterone rapidly decreases brain edema: treatment delayed up to 24 h is still effective Exp. Neurol. 138 1996 246 251
    • (1996) Exp. Neurol. , vol.138 , pp. 246-251
    • Roof, R.L.1    Duvdevani, R.2    Heyburn, J.W.3    Stein, D.G.4
  • 63
    • 0030855406 scopus 로고    scopus 로고
    • Progesterone protects against lipid peroxidation following traumatic brain injury in rats
    • R.L. Roof, S.W. Hoffman, and D.G. Stein Progesterone protects against lipid peroxidation following traumatic brain injury in rats Mol. Chem. Neuropathol. 31 1997 1 11
    • (1997) Mol. Chem. Neuropathol. , vol.31 , pp. 1-11
    • Roof, R.L.1    Hoffman, S.W.2    Stein, D.G.3
  • 64
    • 0034128362 scopus 로고    scopus 로고
    • Gender differences in acute CNS trauma and stroke: Neuroprotective effects of estrogen and progesterone
    • R.L. Roof, and E.D. Hall Gender differences in acute CNS trauma and stroke: neuroprotective effects of estrogen and progesterone J. Neurotrauma. 17 2000 367 388
    • (2000) J. Neurotrauma. , vol.17 , pp. 367-388
    • Roof, R.L.1    Hall, E.D.2
  • 65
    • 0033662080 scopus 로고    scopus 로고
    • Natural progesterone, but not medroxyprogesterone acetate, enhances the beneficial effect of estrogen on exercise-induced myocardial ischemia in postmenopausal women
    • G.M. Rosano, C.M. Webb, S. Chierchia, G.L. Morgani, M. Gabraele, P.M. Sarrel, D. de Ziegler, and P. Collins Natural progesterone, but not medroxyprogesterone acetate, enhances the beneficial effect of estrogen on exercise-induced myocardial ischemia in postmenopausal women J. Am. Coll. Cardiol. 36 2000 2154 2159
    • (2000) J. Am. Coll. Cardiol. , vol.36 , pp. 2154-2159
    • Rosano, G.M.1    Webb, C.M.2    Chierchia, S.3    Morgani, G.L.4    Gabraele, M.5    Sarrel, P.M.6    De Ziegler, D.7    Collins, P.8
  • 66
    • 2942683219 scopus 로고    scopus 로고
    • Expression and localization of 25-Dx, a membrane-associated putative progesterone-binding protein, in the developing Purkinje cell
    • H. Sakamoto, K. Ukena, H. Takemori, M. Okamoto, M. Kawata, and K. Tsutsui Expression and localization of 25-Dx, a membrane-associated putative progesterone-binding protein, in the developing Purkinje cell Neuroscience 126 2004 325 334
    • (2004) Neuroscience , vol.126 , pp. 325-334
    • Sakamoto, H.1    Ukena, K.2    Takemori, H.3    Okamoto, M.4    Kawata, M.5    Tsutsui, K.6
  • 67
    • 61849137768 scopus 로고    scopus 로고
    • Direct inhibition of the mitochondrial permeability transition pore: A possible mechanism for better neuroprotective effects of allopregnanolone over progesterone
    • I. Sayeed, S. Parvez, B. Wali, D. Siemen, and D.G. Stein Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism for better neuroprotective effects of allopregnanolone over progesterone Brain Res. 1263 2009 165 173
    • (2009) Brain Res. , vol.1263 , pp. 165-173
    • Sayeed, I.1    Parvez, S.2    Wali, B.3    Siemen, D.4    Stein, D.G.5
  • 70
    • 0031892683 scopus 로고    scopus 로고
    • Cloning and functional characterization of a sigma receptor from rat brain
    • P. Seth, Y.J. Fei, H.W. Li, W. Huang, F.H. Leibach, and V. Ganapathy Cloning and functional characterization of a sigma receptor from rat brain J. Neurochem. 70 1998 922 931
    • (1998) J. Neurochem. , vol.70 , pp. 922-931
    • Seth, P.1    Fei, Y.J.2    Li, H.W.3    Huang, W.4    Leibach, F.H.5    Ganapathy, V.6
  • 71
    • 25144438043 scopus 로고    scopus 로고
    • Surgical menopause, estrogen, and cognitive function in women: What do the findings tell us?
    • B.B. Sherwin Surgical menopause, estrogen, and cognitive function in women: what do the findings tell us? Ann. N. Y. Acad. Sci. 1052 2005 3 10
    • (2005) Ann. N. Y. Acad. Sci. , vol.1052 , pp. 3-10
    • Sherwin, B.B.1
  • 72
    • 0030818062 scopus 로고    scopus 로고
    • Role of estrogen replacement therapy in memory enhancement and the prevention of neuronal loss associated with Alzheimer's disease
    • J.W. Simpkins, P.S. Green, K.E. Gridley, M. Singh, N.C. de Fiebre, and G. Rajakumar Role of estrogen replacement therapy in memory enhancement and the prevention of neuronal loss associated with Alzheimer's disease Am. J. Med. 103 1997 19S 25S
    • (1997) Am. J. Med. , vol.103
    • Simpkins, J.W.1    Green, P.S.2    Gridley, K.E.3    Singh, M.4    De Fiebre, N.C.5    Rajakumar, G.6
  • 73
    • 0028224213 scopus 로고
    • Ovarian steroid deprivation results in a reversible learning impairment and compromised cholinergic function in female Sprague-Dawley rats
    • M. Singh, E.M. Meyer, W.J. Millard, and J.W. Simpkins Ovarian steroid deprivation results in a reversible learning impairment and compromised cholinergic function in female Sprague-Dawley rats Brain Res. 644 1994 305 312
    • (1994) Brain Res. , vol.644 , pp. 305-312
    • Singh, M.1    Meyer, E.M.2    Millard, W.J.3    Simpkins, J.W.4
  • 74
    • 0028918161 scopus 로고
    • The effect of ovariectomy and estradiol replacement on brain-derived neurotrophic factor messenger ribonucleic acid expression in cortical and hippocampal brain regions of female Sprague-Dawley rats
    • M. Singh, E.M. Meyer, and J.W. Simpkins The effect of ovariectomy and estradiol replacement on brain-derived neurotrophic factor messenger ribonucleic acid expression in cortical and hippocampal brain regions of female Sprague-Dawley rats Endocrinology 136 1995 2320 2324
    • (1995) Endocrinology , vol.136 , pp. 2320-2324
    • Singh, M.1    Meyer, E.M.2    Simpkins, J.W.3
  • 75
    • 0034969952 scopus 로고    scopus 로고
    • Ovarian hormones elicit phosphorylation of Akt and extracellular-signal regulated kinase in explants of the cerebral cortex
    • M. Singh Ovarian hormones elicit phosphorylation of Akt and extracellular-signal regulated kinase in explants of the cerebral cortex Endocrine 14 2001 407 415
    • (2001) Endocrine , vol.14 , pp. 407-415
    • Singh, M.1
  • 76
    • 84872853663 scopus 로고    scopus 로고
    • Progesterone and neuroprotection
    • M. Singh, and C. Su Progesterone and neuroprotection Horm. Behav. 63 2012 284 290
    • (2012) Horm. Behav. , vol.63 , pp. 284-290
    • Singh, M.1    Su, C.2
  • 77
    • 78650592833 scopus 로고    scopus 로고
    • Duration of estrogen deprivation, not chronological age, prevents estrogen's ability to enhance hippocampal synaptic physiology
    • C.C. Smith, L.C. Vedder, A.R. Nelson, T.M. Bredemann, and L.L. McMahon Duration of estrogen deprivation, not chronological age, prevents estrogen's ability to enhance hippocampal synaptic physiology Proc. Natl. Acad. Sci. USA 107 2010 19543 19548
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 19543-19548
    • Smith, C.C.1    Vedder, L.C.2    Nelson, A.R.3    Bredemann, T.M.4    McMahon, L.L.5
  • 78
    • 0028843912 scopus 로고
    • Identification of a putative estrogen response element in the gene encoding brain-derived neurotrophic factor
    • F. Sohrabji, R.C. Miranda, and C.D. Toran-Allerand Identification of a putative estrogen response element in the gene encoding brain-derived neurotrophic factor Proc. Natl. Acad. Sci. USA 92 1995 11110 11114
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11110-11114
    • Sohrabji, F.1    Miranda, R.C.2    Toran-Allerand, C.D.3
  • 79
    • 25144525563 scopus 로고    scopus 로고
    • The case for progesterone
    • D.G. Stein The case for progesterone Ann. N. Y. Acad. Sci. 1052 2005 152 169
    • (2005) Ann. N. Y. Acad. Sci. , vol.1052 , pp. 152-169
    • Stein, D.G.1
  • 80
    • 79961210010 scopus 로고    scopus 로고
    • ERK1/2 and ERK5 have distinct roles in the regulation of brain-derived neurotrophic factor expression
    • C. Su, W. Underwood, N. Rybalchenko, and M. Singh ERK1/2 and ERK5 have distinct roles in the regulation of brain-derived neurotrophic factor expression J. Neurosci. Res. 89 2011 1542 1550
    • (2011) J. Neurosci. Res. , vol.89 , pp. 1542-1550
    • Su, C.1    Underwood, W.2    Rybalchenko, N.3    Singh, M.4
  • 81
    • 84865418488 scopus 로고    scopus 로고
    • Progesterone increases the release of brain-derived neurotrophic factor from glia via progesterone receptor membrane component 1 (Pgrmc1)-dependent ERK5 signaling
    • C. Su, R.L. Cunningham, N. Rybalchenko, and M. Singh Progesterone increases the release of brain-derived neurotrophic factor from glia via progesterone receptor membrane component 1 (Pgrmc1)-dependent ERK5 signaling Endocrinology 153 2012 4389 4400
    • (2012) Endocrinology , vol.153 , pp. 4389-4400
    • Su, C.1    Cunningham, R.L.2    Rybalchenko, N.3    Singh, M.4
  • 83
    • 0033570133 scopus 로고    scopus 로고
    • Progesterone is neuroprotective after acute experimental spinal cord trauma in rats
    • A.J. Thomas, R.P. Nockels, H.Q. Pan, C.I. Shaffrey, and M. Chopp Progesterone is neuroprotective after acute experimental spinal cord trauma in rats Spine 24 1999 2134 2138
    • (1999) Spine , vol.24 , pp. 2134-2138
    • Thomas, A.J.1    Nockels, R.P.2    Pan, H.Q.3    Shaffrey, C.I.4    Chopp, M.5
  • 84
    • 69849099152 scopus 로고    scopus 로고
    • Nongenomic mechanisms of progesterone
    • A.A. Tokmakov, and Y. Fukami Nongenomic mechanisms of progesterone Tsitologiia 51 2009 403 416
    • (2009) Tsitologiia , vol.51 , pp. 403-416
    • Tokmakov, A.A.1    Fukami, Y.2
  • 85
    • 0017229245 scopus 로고
    • Sex steroids and the development of the newborn mouse hypothalamus and preoptic area in vitro: Implications for sexual differentiation
    • C. Toran-Allerand Sex steroids and the development of the newborn mouse hypothalamus and preoptic area in vitro: implications for sexual differentiation Brain Res. 106 1976 407 412
    • (1976) Brain Res. , vol.106 , pp. 407-412
    • Toran-Allerand, C.1
  • 86
    • 0018833686 scopus 로고
    • Sex steroids and the development of the newborn mouse hypothalamus and preoptic area in vitro. II. morphological correlates and hormonal specificity
    • C. Toran-Allerand Sex steroids and the development of the newborn mouse hypothalamus and preoptic area in vitro. II. morphological correlates and hormonal specificity Brain Res. 189 1980 413 427
    • (1980) Brain Res. , vol.189 , pp. 413-427
    • Toran-Allerand, C.1
  • 87
    • 0020695007 scopus 로고
    • Steroid binding to synaptic plasma membrane: Differential binding of glucocorticoids and gonadal steroids
    • A.C. Towle, and P.Y. Sze Steroid binding to synaptic plasma membrane: differential binding of glucocorticoids and gonadal steroids J. Steroid Biochem. 18 1983 135 143
    • (1983) J. Steroid Biochem. , vol.18 , pp. 135-143
    • Towle, A.C.1    Sze, P.Y.2
  • 88
    • 52449092324 scopus 로고    scopus 로고
    • Progesterone in traumatic brain injury: Time to move on to phase III trials
    • M. Vandromme, S.M. Melton, and J.D. Kerby Progesterone in traumatic brain injury: time to move on to phase III trials Crit. Care 12 2008 153
    • (2008) Crit. Care , vol.12 , pp. 153
    • Vandromme, M.1    Melton, S.M.2    Kerby, J.D.3
  • 90
    • 3543027426 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha expression and protein levels after fluid percussion injury in rats: The effect of injury severity and brain temperature
    • discussion 424-5
    • E.A. Vitarbo, K. Chatzipanteli, K. Kinoshita, J.S. Truettner, O.F. Alonso, and W.D. Dietrich Tumor necrosis factor alpha expression and protein levels after fluid percussion injury in rats: the effect of injury severity and brain temperature Neurosurgery 55 2004 416 424 discussion 424-5
    • (2004) Neurosurgery , vol.55 , pp. 416-424
    • Vitarbo, E.A.1    Chatzipanteli, K.2    Kinoshita, K.3    Truettner, J.S.4    Alonso, O.F.5    Dietrich, W.D.6
  • 91
    • 79951937638 scopus 로고    scopus 로고
    • Improved behavioral outcomes after progesterone administration in aged male rats with traumatic brain injury
    • B. Wali, I. Sayeed, and D.G. Stein Improved behavioral outcomes after progesterone administration in aged male rats with traumatic brain injury Restor. Neurol. Neurosci. 29 2011 61 71
    • (2011) Restor. Neurol. Neurosci. , vol.29 , pp. 61-71
    • Wali, B.1    Sayeed, I.2    Stein, D.G.3
  • 92
    • 0345735759 scopus 로고    scopus 로고
    • The preclinical biology of a new potent and selective progestin: Trimegestone
    • R.C. Winneker, D. Bitran, and Z. Zhang The preclinical biology of a new potent and selective progestin: trimegestone Steroids 68 2003 915 920
    • (2003) Steroids , vol.68 , pp. 915-920
    • Winneker, R.C.1    Bitran, D.2    Zhang, Z.3
  • 94
    • 79951835437 scopus 로고    scopus 로고
    • Ovarian hormone deficiency reduces intrinsic excitability and abolishes acute estrogen sensitivity in hippocampal CA1 pyramidal neurons
    • W.W. Wu, J.P. Adelman, and J. Maylie Ovarian hormone deficiency reduces intrinsic excitability and abolishes acute estrogen sensitivity in hippocampal CA1 pyramidal neurons J. Neurosci. 31 2011 2638 2648
    • (2011) J. Neurosci. , vol.31 , pp. 2638-2648
    • Wu, W.W.1    Adelman, J.P.2    Maylie, J.3
  • 95
    • 43249131666 scopus 로고    scopus 로고
    • Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: A randomized controlled trial
    • G. Xiao, J. Wei, W. Yan, W. Wang, and Z. Lu Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial Crit. Care 12 2008 R61
    • (2008) Crit. Care , vol.12 , pp. 61
    • Xiao, G.1    Wei, J.2    Yan, W.3    Wang, W.4    Lu, Z.5
  • 97
    • 0033427196 scopus 로고    scopus 로고
    • Age-associated impairment in brain MAPK signal pathways and the effect of caloric restriction in Fischer 344 rats
    • X. Zhen, K. Uryu, G. Cai, G.P. Johnson, and E. Friedman Age-associated impairment in brain MAPK signal pathways and the effect of caloric restriction in Fischer 344 rats J. Gerontol. A Biol. Sci. Med. Sci. 54 1999 B539 B548
    • (1999) J. Gerontol. A Biol. Sci. Med. Sci. , vol.54
    • Zhen, X.1    Uryu, K.2    Cai, G.3    Johnson, G.P.4    Friedman, E.5
  • 98
    • 0344885580 scopus 로고    scopus 로고
    • Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor
    • Y. Zhu, J. Bond, and P. Thomas Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor Proc. Natl. Acad. Sci. USA 100 2003 2237 2242
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 2237-2242
    • Zhu, Y.1    Bond, J.2    Thomas, P.3
  • 99
    • 0344885581 scopus 로고    scopus 로고
    • Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes
    • Y. Zhu, C.D. Rice, Y. Pang, M. Pace, and P. Thomas Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes Proc. Natl. Acad. Sci. USA 100 2003 2231 2236
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 2231-2236
    • Zhu, Y.1    Rice, C.D.2    Pang, Y.3    Pace, M.4    Thomas, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.