메뉴 건너뛰기




Volumn 2, Issue AUG, 2010, Pages

Beyond the HPA axis: Progesterone-derived neuroactive steroids in human stress and emotion

Author keywords

3 hydroxy 5 pregnan 20 one; Affiliation; Allopregnanolone; Progesterone; Social motivation; Stress

Indexed keywords


EID: 84865580017     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2011.00019     Document Type: Review
Times cited : (87)

References (130)
  • 3
    • 2342579466 scopus 로고    scopus 로고
    • Activation of GABA(A) receptors containing the alpha4 subunit by GABA and pentobarbital
    • Akk, G., Bracamontes, J., and Steinbach, J. H. (2004a). Activation of GABA(A) receptors containing the alpha4 subunit by GABA and pentobarbital. J. Physiol. (Lond.) 556, 387-399.
    • (2004) J. Physiol. (Lond. ) , vol.556 , pp. 387-399
    • Akk, G.1    Bracamontes, J.2    Steinbach, J.H.3
  • 6
    • 34248645660 scopus 로고    scopus 로고
    • The interaction of neuroactive steroids and GABA in the development of neuropsychiatric disorders in women
    • Amin,Z.,Mason,G. F.,Cavus,I.,Krystal, J. H., Rothman, D. L., and Epperson, C. N. (2006). The interaction of neuroactive steroids and GABA in the development of neuropsychiatric disorders in women. Pharmacol. Biochem. Behav. 84, 635-643.
    • (2006) Pharmacol. Biochem. Behav. , vol.84 , pp. 635-643
    • Amin, Z.1    Mason, G.F.2    Cavus, I.3    Krystal, J.H.4    Rothman, D.L.5    Epperson, C.N.6
  • 7
    • 67650585823 scopus 로고    scopus 로고
    • Sex steroid induced negative mood may be explained by the paradoxical effect mediated by GABAA modulators
    • Andreen, L., Nyberg, S., Turkmen, S., van Wingen, G., Fernandez, G., and Backstrom, T. (2009). Sex steroid induced negative mood may be explained by the paradoxical effect mediated by GABAA modulators. Psychoneuroendocrinology 34, 1121-1132.
    • (2009) Psychoneuroendocrinology , vol.34 , pp. 1121-1132
    • Andreen, L.1    Nyberg, S.2    Turkmen, S.3    van Wingen, G.4    Fernandez, G.5    Backstrom, T.6
  • 8
    • 56749158610 scopus 로고    scopus 로고
    • Progestin receptor-mediated reduction of anxiety-like behavior in male rats
    • doi: 10.1371/journal.pone.0003606
    • Auger, C. J., and Forbes-Lorman, R. M. (2008). Progestin receptor-mediated reduction of anxiety-like behavior in male rats. PLoS ONE 3, e3606. doi: 10.1371/journal.pone.0003606
    • (2008) PLoS ONE , vol.3
    • Auger, C.J.1    Forbes-Lorman, R.M.2
  • 10
    • 0030977218 scopus 로고    scopus 로고
    • The effects of inhibitors of GABAergic transmission and stress on brain and plasma allopregnanolone concentrations
    • Barbaccia, M. L., Roscetti, G., Trabucchi, M., Purdy, R. H., Mostallino, M. C., Concas,A., and Biggio, G. (1997). The effects of inhibitors of GABAergic transmission and stress on brain and plasma allopregnanolone concentrations. Br. J. Pharmacol. 120, 1582-1588.
    • (1997) Br. J. Pharmacol. , vol.120 , pp. 1582-1588
    • Barbaccia, M.L.1    Roscetti, G.2    Trabucchi, M.3    Purdy, R.H.4    Mostallino, M.C.5    Concas, A.6    Biggio, G.7
  • 13
    • 0025918687 scopus 로고
    • Anxiolytic effects of 3 alpha-hydroxy-5 alpha[beta]pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor
    • Bitran, D., Hilvers, R. J., and Kellogg, C. K. (1991). Anxiolytic effects of 3 alpha-hydroxy-5 alpha[beta]pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor. Brain Res. 561, 157-161.
    • (1991) Brain Res , vol.561 , pp. 157-161
    • Bitran, D.1    Hilvers, R.J.2    Kellogg, C.K.3
  • 14
    • 0028916048 scopus 로고
    • Anxiolytic effect of progesterone is mediated by the neurosteroid allopregnanolone at brain GABAA receptors
    • Bitran, D., Shiekh, M., and McLeod, M. (1995). Anxiolytic effect of progesterone is mediated by the neurosteroid allopregnanolone at brain GABAA receptors. J. Neuroendocrinol. 7, 171-177.
    • (1995) J. Neuroendocrinol. , vol.7 , pp. 171-177
    • Bitran, D.1    Shiekh, M.2    McLeod, M.3
  • 15
    • 11244351658 scopus 로고    scopus 로고
    • Factors related to postpartum depressive symptoms in low-income women
    • Boury, J. M., Larkin, K. T., and Krummel, D. A. (2004). Factors related to postpartum depressive symptoms in low-income women. Women Health 39, 19-34.
    • (2004) Women Health , vol.39 , pp. 19-34
    • Boury, J.M.1    Larkin, K.T.2    Krummel, D.A.3
  • 17
    • 0030968281 scopus 로고    scopus 로고
    • The anxiolytic-like effects of the neurosteroid allopregnanolone: interactions with GABA(A) receptors
    • Brot,M. D.,Akwa,Y.,Purdy,R. H.,Koob, G. F., and Britton, K. T. (1997). The anxiolytic-like effects of the neurosteroid allopregnanolone: interactions with GABA(A) receptors. Eur. J. Pharmacol. 325, 1-7.
    • (1997) Eur. J. Pharmacol. , vol.325 , pp. 1-7
    • Brot, M.D.1    Akwa, Y.2    Purdy, R.H.3    Koob, G.F.4    Britton, K.T.5
  • 21
    • 0026603924 scopus 로고
    • The 5 alpha-reductase in the brain: molecular aspects and relation to brain function
    • Celotti, F., Melcangi, R. C., and Martini,L. (1992). The 5 alpha-reductase in the brain: molecular aspects and relation to brain function. Front. Neuroendocrinol. 13, 163-215.
    • (1992) Front. Neuroendocrinol. , vol.13 , pp. 163-215
    • Celotti, F.1    Melcangi, R.C.2    Martini, L.3
  • 22
    • 0029067030 scopus 로고
    • Gas chromatographic-mass fragmentographic quantitation of 3 alpha-hydroxy-5 alpha-pregnan20-one (allopregnanolone) and its precursors in blood and brain of adrenalectomized and castrated rats
    • Cheney, D. L., Uzunov, D., Costa, E., and Guidotti, A. (1995). Gas chromatographic-mass fragmentographic quantitation of 3 alpha-hydroxy-5 alpha-pregnan20-one (allopregnanolone) and its precursors in blood and brain of adrenalectomized and castrated rats. J. Neurosci. 15, 4641-4650.
    • (1995) J. Neurosci. , vol.15 , pp. 4641-4650
    • Cheney, D.L.1    Uzunov, D.2    Costa, E.3    Guidotti, A.4
  • 23
    • 60449113181 scopus 로고    scopus 로고
    • Hormonal, cardiovascular, and subjective responses to acute stress in smokers
    • Childs, E., and de Wit, H. (2009). Hormonal, cardiovascular, and subjective responses to acute stress in smokers. Psychopharmacology (Berl.) 203, 1-12.
    • (2009) Psychopharmacology (Berl. ) , vol.203 , pp. 1-12
    • Childs, E.1    de Wit, H.2
  • 24
    • 77950669330 scopus 로고    scopus 로고
    • Cardiovascular, hormonal, and emotional responses to the TSST in relation to sex and menstrual cycle phase
    • Childs, E., Dlugos, A., and De Wit, H. (2010a). Cardiovascular, hormonal, and emotional responses to the TSST in relation to sex and menstrual cycle phase. Psychophysiology 47, 550-559.
    • (2010) Psychophysiology , vol.47 , pp. 550-559
    • Childs, E.1    Dlugos, A.2    De Wit, H.3
  • 25
    • 76749142519 scopus 로고    scopus 로고
    • Effects of acute progesterone administration upon responses to acute psychosocial stress in men
    • Childs, E., Van Dam, N. T., and de Wit, H. (2010b). Effects of acute progesterone administration upon responses to acute psychosocial stress in men. Exp. Clin. Psychopharmacol. 18, 78-86.
    • (2010) Exp. Clin. Psychopharmacol. , vol.18 , pp. 78-86
    • Childs, E.1    Van Dam, N.T.2    de Wit, H.3
  • 27
    • 0033953033 scopus 로고    scopus 로고
    • Neurosteroids: biosynthesis and function of these novel neuromodulators
    • Compagnone, N. A., and Mellon, S. H. (2000). Neurosteroids: biosynthesis and function of these novel neuromodulators. Front. Neuroendocrinol. 21, 1-56.
    • (2000) Front. Neuroendocrinol. , vol.21 , pp. 1-56
    • Compagnone, N.A.1    Mellon, S.H.2
  • 30
    • 0033215376 scopus 로고    scopus 로고
    • Stress and cognition: are corticosteroids good or bad guys?
    • de Kloet, E. R., Oitzl, M. S., and Joels, M. (1999). Stress and cognition: are corticosteroids good or bad guys?Trends Neurosci. 22, 422-426.
    • (1999) Trends Neurosci , vol.22 , pp. 422-426
    • de Kloet, E.R.1    Oitzl, M.S.2    Joels, M.3
  • 32
    • 0034910592 scopus 로고    scopus 로고
    • Effects of acute progesterone administration in healthy postmenopausal women and normally-cycling women
    • de Wit, H., Schmitt, L., Purdy, R., and Hauger, R. (2001). Effects of acute progesterone administration in healthy postmenopausal women and normally-cycling women. Psychoneuroendocrinology 26, 697-710.
    • (2001) Psychoneuroendocrinology , vol.26 , pp. 697-710
    • de Wit, H.1    Schmitt, L.2    Purdy, R.3    Hauger, R.4
  • 33
    • 26644451838 scopus 로고    scopus 로고
    • A neurobehavioral model of affiliative bonding: implications for conceptualizing a human trait of affiliation
    • discussion 2005 350-395
    • Depue, R. A., and Morrone-Strupinsky, J. V. (2005). A neurobehavioral model of affiliative bonding: implications for conceptualizing a human trait of affiliation. Behav. Brain Sci. 28, 313-350; discussion 350-395.
    • Behav. Brain Sci. , vol.28 , pp. 313-350
    • Depue, R.A.1    Morrone-Strupinsky, J.V.2
  • 34
    • 2442604444 scopus 로고    scopus 로고
    • Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research
    • Dickerson, S. S., and Kemeny, M. E. (2004). Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research. Psychol. Bull. 130, 355-391.
    • (2004) Psychol. Bull. , vol.130 , pp. 355-391
    • Dickerson, S.S.1    Kemeny, M.E.2
  • 36
    • 3543092145 scopus 로고    scopus 로고
    • Effects of PhD examination stress on allopregnanolone and cortisol plasma levels and peripheral benzodiazepine receptor density
    • Droogleever Fortuyn, H. A., van Broekhoven, F., Span, P. N., Backstrom, T., Zitman, F. G., and Verkes, R. J. (2004). Effects of PhD examination stress on allopregnanolone and cortisol plasma levels and peripheral benzodiazepine receptor density. Psychoneuroendocrinology 29, 1341-1344.
    • (2004) Psychoneuroendocrinology , vol.29 , pp. 1341-1344
    • Droogleever Fortuyn, H.A.1    van Broekhoven, F.2    Span, P.N.3    Backstrom, T.4    Zitman, F.G.5    Verkes, R.J.6
  • 37
    • 34250847013 scopus 로고    scopus 로고
    • Neurosteroids, neuroactive steroids, and symptoms of affective disorders
    • Dubrovsky, B. (2006). Neurosteroids, neuroactive steroids, and symptoms of affective disorders. Pharmacol. Biochem. Behav. 84, 644-655.
    • (2006) Pharmacol. Biochem. Behav. , vol.84 , pp. 644-655
    • Dubrovsky, B.1
  • 39
    • 0036713954 scopus 로고    scopus 로고
    • Cortical gamma-aminobutyric acid levels across the menstrual cycle in healthy women and those with premenstrual dysphoric disorder: a proton magnetic resonance spectroscopy study
    • Epperson, C. N., Haga, K., Mason, G. F., Sellers, E., Gueorguieva, R., Zhang, W., Weiss, E., Rothman, D. L., and Krystal, J. H. (2002). Cortical gamma-aminobutyric acid levels across the menstrual cycle in healthy women and those with premenstrual dysphoric disorder: a proton magnetic resonance spectroscopy study. Arch. Gen. Psychiatry 59, 851-858.
    • (2002) Arch. Gen. Psychiatry , vol.59 , pp. 851-858
    • Epperson, C.N.1    Haga, K.2    Mason, G.F.3    Sellers, E.4    Gueorguieva, R.5    Zhang, W.6    Weiss, E.7    Rothman, D.L.8    Krystal, J.H.9
  • 41
    • 0031396408 scopus 로고    scopus 로고
    • Cortisol, hedonics, and maternal responsiveness in human mothers
    • Fleming, A. S., Steiner, M., and Corter, C. (1997). Cortisol, hedonics, and maternal responsiveness in human mothers. Horm. Behav. 32, 85-98.
    • (1997) Horm. Behav. , vol.32 , pp. 85-98
    • Fleming, A.S.1    Steiner, M.2    Corter, C.3
  • 42
    • 0027381920 scopus 로고
    • Anxiolytic metabolites of progesterone: correlation with mood and performance measures following oral progesterone administration to healthy female volunteers
    • Freeman, E. W., Purdy, R. H., Coutifaris, C., Rickels, K., and Paul, S. M. (1993). Anxiolytic metabolites of progesterone: correlation with mood and performance measures following oral progesterone administration to healthy female volunteers. Neuroendocrinology 58, 478-484.
    • (1993) Neuroendocrinology , vol.58 , pp. 478-484
    • Freeman, E.W.1    Purdy, R.H.2    Coutifaris, C.3    Rickels, K.4    Paul, S.M.5
  • 44
    • 0032511643 scopus 로고    scopus 로고
    • The neurosteroids,progesterone and 3alpha,5alpha-THP, enhance sexual motivation, receptivity, and proceptivity in female rats
    • Frye, C. A., Bayon, L. E., Pursnani, N. K., and Purdy, R. H. (1998). The neurosteroids,progesterone and 3alpha,5alpha-THP, enhance sexual motivation, receptivity, and proceptivity in female rats. Brain Res. 808, 72-83.
    • (1998) Brain Res , vol.808 , pp. 72-83
    • Frye, C.A.1    Bayon, L.E.2    Pursnani, N.K.3    Purdy, R.H.4
  • 45
    • 33644514957 scopus 로고    scopus 로고
    • 3alphahydroxy-5alpha-pregnan-20-one in the midbrain ventral tegmental area mediates social, sexual, and affective behaviors
    • Frye, C. A., Rhodes, M. E., Petralia, S. M., Walf, A. A., Sumida, K., and Edinger, K. L. (2006). 3alphahydroxy-5alpha-pregnan-20-one in the midbrain ventral tegmental area mediates social, sexual, and affective behaviors. Neuroscience 138, 1007-1014.
    • (2006) Neuroscience , vol.138 , pp. 1007-1014
    • Frye, C.A.1    Rhodes, M.E.2    Petralia, S.M.3    Walf, A.A.4    Sumida, K.5    Edinger, K.L.6
  • 46
    • 1642345295 scopus 로고    scopus 로고
    • Progesterone enhances motor, anxiolytic, analgesic, and antidepressive behavior of wild-type mice, but not those deficient in type 1 5 alpha-reductase
    • Frye, C. A., Walf, A. A., Rhodes, M. E., and Harney, J. P. (2004). Progesterone enhances motor, anxiolytic, analgesic, and antidepressive behavior of wild-type mice, but not those deficient in type 1 5 alpha-reductase. Brain Res. 1004, 116-124.
    • (2004) Brain Res , vol.1004 , pp. 116-124
    • Frye, C.A.1    Walf, A.A.2    Rhodes, M.E.3    Harney, J.P.4
  • 48
    • 34548558865 scopus 로고    scopus 로고
    • Neurosteroids in the context of stress: implications for depressive disorders
    • Girdler, S. S., and Klatzkin, R. (2007). Neurosteroids in the context of stress: implications for depressive disorders. Pharmacol. Ther. 116, 125-139.
    • (2007) Pharmacol. Ther. , vol.116 , pp. 125-139
    • Girdler, S.S.1    Klatzkin, R.2
  • 49
    • 0035336907 scopus 로고    scopus 로고
    • Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder
    • Girdler, S. S., Straneva, P. A., Light, K. C., Pedersen, C. A., and Morrow, A. L. (2001). Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder. Biol. Psychiatry 49, 788-797.
    • (2001) Biol. Psychiatry , vol.49 , pp. 788-797
    • Girdler, S.S.1    Straneva, P.A.2    Light, K.C.3    Pedersen, C.A.4    Morrow, A.L.5
  • 50
    • 0035663937 scopus 로고    scopus 로고
    • The sociallyisolated mouse: a model to study the putative role of allopregnanolone and 5alpha-dihydroprogesterone in psychiatric disorders
    • Guidotti, A., Dong, E., Matsumoto, K., Pinna, G., Rasmusson, A. M., and Costa, E. (2001). The sociallyisolated mouse: a model to study the putative role of allopregnanolone and 5alpha-dihydroprogesterone in psychiatric disorders. Brain Res. Brain Res. Rev. 37, 110-115.
    • (2001) Brain Res. Brain Res. Rev , vol.37 , pp. 110-115
    • Guidotti, A.1    Dong, E.2    Matsumoto, K.3    Pinna, G.4    Rasmusson, A.M.5    Costa, E.6
  • 51
    • 0023175459 scopus 로고
    • Structure-activity relationships for steroid interaction with the gamma-aminobutyric acidA receptor complex
    • Harrison, N. L., Majewska, M. D., Harrington, J. W., and Barker, J. L. (1987). Structure-activity relationships for steroid interaction with the gamma-aminobutyric acidA receptor complex. J. Pharmacol. Exp. Ther. 241, 346-353.
    • (1987) J. Pharmacol. Exp. Ther. , vol.241 , pp. 346-353
    • Harrison, N.L.1    Majewska, M.D.2    Harrington, J.W.3    Barker, J.L.4
  • 52
    • 0021741846 scopus 로고
    • Modulation of the GABA receptor complex by a steroid anaesthetic
    • Harrison, N. L., and Simmonds, M. A. (1984). Modulation of the GABA receptor complex by a steroid anaesthetic. Brain Res. 323, 287-292.
    • (1984) Brain Res , vol.323 , pp. 287-292
    • Harrison, N.L.1    Simmonds, M.A.2
  • 53
    • 0024409096 scopus 로고
    • Effect of acute ether or restraint stress on plasma corticotropin-releasing hormone, vasopressin and oxytocin levels in the rat
    • Hashimoto, K., Murakami, K., Takao, T., Makino, S., Sugawara, M., and Ota, Z. (1989). Effect of acute ether or restraint stress on plasma corticotropin-releasing hormone, vasopressin and oxytocin levels in the rat. Acta Med. Okayama 43, 161-167.
    • (1989) Acta Med. Okayama , vol.43 , pp. 161-167
    • Hashimoto, K.1    Murakami, K.2    Takao, T.3    Makino, S.4    Sugawara, M.5    Ota, Z.6
  • 54
    • 0347627798 scopus 로고    scopus 로고
    • Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress
    • Heinrichs, M., Baumgartner, T., Kirschbaum, C., and Ehlert, U. (2003). Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress. Biol. Psychiatry 54, 1389-1398.
    • (2003) Biol. Psychiatry , vol.54 , pp. 1389-1398
    • Heinrichs, M.1    Baumgartner, T.2    Kirschbaum, C.3    Ehlert, U.4
  • 55
    • 0023808877 scopus 로고
    • Social relationships and health
    • House, J. S., Landis, K. R., and Umberson, D. (1988). Social relationships and health. Science 241, 540-545.
    • (1988) Science , vol.241 , pp. 540-545
    • House, J.S.1    Landis, K.R.2    Umberson, D.3
  • 56
    • 0030905913 scopus 로고    scopus 로고
    • A neurobiological basis of social attachment
    • Insel, T. R. (1997). A neurobiological basis of social attachment. Am. J. Psychiatry 154, 726-735.
    • (1997) Am. J. Psychiatry , vol.154 , pp. 726-735
    • Insel, T.R.1
  • 57
    • 33646246383 scopus 로고    scopus 로고
    • Corticosteroid effects in the brain: U-shape it
    • Joels, M. (2006). Corticosteroid effects in the brain: U-shape it. Trends Pharmacol. Sci. 27, 244-250.
    • (2006) Trends Pharmacol. Sci. , vol.27 , pp. 244-250
    • Joels, M.1
  • 59
    • 0023819525 scopus 로고
    • Opiate modulation of separation-induced distress in non-human primates
    • Kalin, N. H., Shelton, S. E., and Barksdale, C. M. (1988). Opiate modulation of separation-induced distress in non-human primates. Brain Res. 440, 285-292.
    • (1988) Brain Res , vol.440 , pp. 285-292
    • Kalin, N.H.1    Shelton, S.E.2    Barksdale, C.M.3
  • 60
    • 0029564647 scopus 로고
    • Opiate systems in mother and infant primates coordinate intimate contact during reunion
    • Kalin, N. H., Shelton, S. E., and Lynn, D. E. (1995). Opiate systems in mother and infant primates coordinate intimate contact during reunion. Psychoneuroendocrinology 20, 735-742.
    • (1995) Psychoneuroendocrinology , vol.20 , pp. 735-742
    • Kalin, N.H.1    Shelton, S.E.2    Lynn, D.E.3
  • 61
    • 0018648787 scopus 로고
    • In vivo uptake and metabolism of [3H]progesterone and [3H]5 alpha-dihydroprogesterone by rat CNS and anterior pituitary: tissue concentration of progesterone itself or metabolites? J
    • Karavolas, H. J., Hodges, D. R., and O'Brien, D. J. (1979). In vivo uptake and metabolism of [3H]progesterone and [3H]5 alpha-dihydroprogesterone by rat CNS and anterior pituitary: tissue concentration of progesterone itself or metabolites? J. Steroid Biochem. 11, 863-872.
    • (1979) Steroid Biochem , vol.11 , pp. 863-872
    • Karavolas, H.J.1    Hodges, D.R.2    O'Brien, D.J.3
  • 63
    • 0033672097 scopus 로고    scopus 로고
    • Antidepressant-like effect of the neurosteroid 3alphahydroxy-5alpha-pregnan-20-one in mice forced swim test
    • Khisti, R. T., Chopde, C. T., and Jain,S. P. (2000).Antidepressant-like effect of the neurosteroid 3alphahydroxy-5alpha-pregnan-20-one in mice forced swim test. Pharmacol. Biochem. Behav. 67, 137-143.
    • (2000) Pharmacol. Biochem. Behav. , vol.67 , pp. 137-143
    • Khisti, R.T.1    Chopde, C.T.2    Jain, S.P.3
  • 64
    • 0034650302 scopus 로고    scopus 로고
    • Profiling neurosteroids in cerebrospinal fluids and plasma by gas chromatography/electron capture negative chemical ionization mass spectrometry
    • Kim, Y. S., Zhang, H., and Kim, H. Y. (2000). Profiling neurosteroids in cerebrospinal fluids and plasma by gas chromatography/electron capture negative chemical ionization mass spectrometry. Anal. Biochem. 277, 187-195.
    • (2000) Anal. Biochem. , vol.277 , pp. 187-195
    • Kim, Y.S.1    Zhang, H.2    Kim, H.Y.3
  • 65
    • 0027517172 scopus 로고
    • The 'Trier Social Stress Test' a tool for investigating psychobiological stress responses in a laboratory setting
    • Kirschbaum, C., Pirke, K. M., and Hellhammer, D. H. (1993). The 'Trier Social Stress Test' a tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology 28, 76-81.
    • (1993) Neuropsychobiology , vol.28 , pp. 76-81
    • Kirschbaum, C.1    Pirke, K.M.2    Hellhammer, D.H.3
  • 66
    • 33751224171 scopus 로고    scopus 로고
    • Associations of histories of depression and PMDD diagnosis with allopregnanolone concentrations following the oral administration of micronized progesterone
    • Klatzkin, R. R., Morrow, A. L., Light, K. C., Pedersen, C. A., and Girdler, S. S. (2006a). Associations of histories of depression and PMDD diagnosis with allopregnanolone concentrations following the oral administration of micronized progesterone. Psychoneuroendocrinology 31, 1208-1219.
    • (2006) Psychoneuroendocrinology , vol.31 , pp. 1208-1219
    • Klatzkin, R.R.1    Morrow, A.L.2    Light, K.C.3    Pedersen, C.A.4    Girdler, S.S.5
  • 67
    • 29144512348 scopus 로고    scopus 로고
    • Histories of depression, allopregnanolone responses to stress, and premenstrual symptoms in women
    • Klatzkin, R. R., Morrow, A. L., Light, K. C., Pedersen, C. A., and Girdler, S. S. (2006b). Histories of depression, allopregnanolone responses to stress, and premenstrual symptoms in women. Biol. Psychol. 71, 2-11.
    • (2006) Biol. Psychol. , vol.71 , pp. 2-11
    • Klatzkin, R.R.1    Morrow, A.L.2    Light, K.C.3    Pedersen, C.A.4    Girdler, S.S.5
  • 68
    • 0034628965 scopus 로고    scopus 로고
    • Prolonged intracerebroventricular infusion of neurosteroids affects cognitive performances in the mouse
    • Ladurelle, N., Eychenne, B., Denton, D., Blair-West, J., Schumacher, M., Robel, P., and Baulieu, E. (2000). Prolonged intracerebroventricular infusion of neurosteroids affects cognitive performances in the mouse. Brain Res. 858, 371-379.
    • (2000) Brain Res , vol.858 , pp. 371-379
    • Ladurelle, N.1    Eychenne, B.2    Denton, D.3    Blair-West, J.4    Schumacher, M.5    Robel, P.6    Baulieu, E.7
  • 71
    • 35748961429 scopus 로고    scopus 로고
    • The effects of stress and stress hormones on human cognition: implications for the field of brain and cognition
    • Lupien, S. J., Maheu, F., Tu, M., Fiocco, A., and Schramek, T. E. (2007). The effects of stress and stress hormones on human cognition: implications for the field of brain and cognition. Brain Cogn. 65, 209-237.
    • (2007) Brain Cogn , vol.65 , pp. 209-237
    • Lupien, S.J.1    Maheu, F.2    Tu, M.3    Fiocco, A.4    Schramek, T.E.5
  • 72
    • 33947637046 scopus 로고    scopus 로고
    • GABA and neuroactive steroid interactions in glia: new roles for old players? Curr
    • Magnaghi, V. (2007). GABA and neuroactive steroid interactions in glia: new roles for old players? Curr. Neuropharmacol. 5, 47-64.
    • (2007) Neuropharmacol , vol.5 , pp. 47-64
    • Magnaghi, V.1
  • 73
    • 0022483382 scopus 로고
    • Steroid hormone metabolites are barbituratelike modulators of the GABA receptor
    • Majewska, M. D., Harrison, N. L., Schwartz, R. D., Barker, J. L., and Paul, S. M. (1986). Steroid hormone metabolites are barbituratelike modulators of the GABA receptor. Science 232, 1004-1007.
    • (1986) Science , vol.232 , pp. 1004-1007
    • Majewska, M.D.1    Harrison, N.L.2    Schwartz, R.D.3    Barker, J.L.4    Paul, S.M.5
  • 74
    • 77951215312 scopus 로고    scopus 로고
    • The endocrinology of exclusion: rejection elicits motivationally tuned changes in progesterone
    • Maner, J. K., Miller, S. L., Schmidt, N. B., and Eckel, L. A. (2010). The endocrinology of exclusion: rejection elicits motivationally tuned changes in progesterone. Psychol. Sci. 21, 581-588.
    • (2010) Psychol. Sci. , vol.21 , pp. 581-588
    • Maner, J.K.1    Miller, S.L.2    Schmidt, N.B.3    Eckel, L.A.4
  • 76
    • 0020400067 scopus 로고
    • Intimacy motivation and psychosocial adjustment: a longitudinal study
    • McAdams, D. P., and Vaillant, G. E. (1982). Intimacy motivation and psychosocial adjustment: a longitudinal study. J. Pers. Assess. 46, 586.
    • (1982) J. Pers. Assess. , vol.46 , pp. 586
    • McAdams, D.P.1    Vaillant, G.E.2
  • 77
    • 0024653402 scopus 로고
    • Motivational factors in health and disease
    • McClelland, D. C. (1989). Motivational factors in health and disease. Am. Psychol. 44, 675.
    • (1989) Am. Psychol. , vol.44 , pp. 675
    • McClelland, D.C.1
  • 78
    • 0242691232 scopus 로고    scopus 로고
    • Neurosteroids, GABAA receptors, and escalated aggressive behavior
    • Miczek, K. A., Fish, E. W., and De Bold, J. F. (2003). Neurosteroids, GABAA receptors, and escalated aggressive behavior. Horm. Behav. 44, 242-257.
    • (2003) Horm. Behav , vol.44 , pp. 242-257
    • Miczek, K.A.1    Fish, E.W.2    De Bold, J.F.3
  • 79
    • 34548557525 scopus 로고    scopus 로고
    • Recent developments in the significance and therapeutic relevance of neuroactive steroids Introduction to the special issue
    • Morrow, A. L. (2007). Recent developments in the significance and therapeutic relevance of neuroactive steroids Introduction to the special issue. Pharmacol. Ther. 116, 1-6.
    • (2007) Pharmacol. Ther. , vol.116 , pp. 16
    • Morrow, A.L.1
  • 81
    • 0023238727 scopus 로고
    • The anaesthetic potency of 3 alpha-hydroxy5 alpha-pregnan-20-one and 3 alpha-hydroxy-5 beta-pregnan-20one determined with an intravenous EEG-threshold method in male rats
    • Norberg, L., Wahlstrom, G., and Backstrom, T. (1987). The anaesthetic potency of 3 alpha-hydroxy5 alpha-pregnan-20-one and 3 alpha-hydroxy-5 beta-pregnan-20one determined with an intravenous EEG-threshold method in male rats. Pharmacol. Toxicol. 61, 4247.
    • (1987) Pharmacol. Toxicol. , vol.61 , pp. 42-47
    • Norberg, L.1    Wahlstrom, G.2    Backstrom, T.3
  • 82
    • 33744467698 scopus 로고    scopus 로고
    • Action by and sensitivity to neuroactive steroids in menstrual cycle related CNS disorders
    • N-Wihlback, A. C., SundstromPoromaa, I., and Backstrom, T. (2006). Action by and sensitivity to neuroactive steroids in menstrual cycle related CNS disorders. Psychopharmacology (Berl.) 186, 388401.
    • (2006) Psychopharmacology (Berl.) , vol.186 , pp. 388-401
    • N-Wihlback, A.C.1    SundstromPoromaa, I.2    Backstrom, T.3
  • 83
    • 2442536988 scopus 로고    scopus 로고
    • Neural pathways controlling central and peripheral oxytocin release during stress
    • Onaka, T. (2004). Neural pathways controlling central and peripheral oxytocin release during stress. J. Neuroendocrinol. 16, 308312.
    • (2004) J. Neuroendocrinol. , vol.16 , pp. 308-312
    • Onaka, T.1
  • 85
    • 0030560881 scopus 로고    scopus 로고
    • Theneurosteroid tetrahydroprogesterone attenuates the endocrine response to stress and exerts glucocorticoidlike effects on vasopressin gene transcription in the rat hypothalamus
    • Patchev,V.K.,Hassan,A.H.,Holsboer,D. F.,andAlmeida,O.F.(1996).Theneurosteroid tetrahydroprogesterone attenuates the endocrine response to stress and exerts glucocorticoidlike effects on vasopressin gene transcription in the rat hypothalamus. Neuropsychopharmacology 15, 533540.
    • (1996) Neuropsychopharmacology Almeida , vol.15 , pp. 533-540
    • Patchev, V.K.1    Hassan, A.H.2    Holsboer, D.F.3
  • 86
    • 0027990941 scopus 로고
    • The neurosteroid tetrahydroprogesterone counteracts corticotropinreleasing hormone-induced anxiety and alters the release and gene expression of corticotropinreleasing hormone in the rat hypothalamus
    • Patchev, V. K., Shoaib, M., Holsboer, F., and Almeida, O. F. (1994). The neurosteroid tetrahydroprogesterone counteracts corticotropinreleasing hormone-induced anxiety and alters the release and gene expression of corticotropinreleasing hormone in the rat hypothalamus. Neuroscience 62, 265271.
    • (1994) Neuroscience , vol.62 , pp. 265-271
    • Patchev, V.K.1    Shoaib, M.2    Holsboer, F.3    Almeida, O.F.4
  • 87
    • 0026579057 scopus 로고
    • Neuroactive steroids
    • Paul, S. M., and Purdy, R. H. (1992). Neuroactive steroids. FASEB J. 6, 23112322.
    • (1992) FASEB J , vol.6 , pp. 2311-2322
    • Paul, S.M.1    Purdy, R.H.2
  • 88
    • 0033736883 scopus 로고    scopus 로고
    • Determination of progesterone and some of its neuroactive ring A-reduced metabolites in human serum
    • Pearson Murphy, B. E., and Allison, C. M. (2000). Determination of progesterone and some of its neuroactive ring A-reduced metabolites in human serum. J. Steroid Biochem. Mol. Biol. 74, 137142.
    • (2000) J. Steroid Biochem. Mol. Biol. , vol.74 , pp. 137-142
    • Pearson Murphy, B.E.1    Allison, C.M.2
  • 89
    • 4644368990 scopus 로고    scopus 로고
    • Neurosteroids and neuroactive drugs in mental disorders
    • Pisu, M. G., and Serra, M. (2004). Neurosteroids and neuroactive drugs in mental disorders. Life Sci. 74, 31813197.
    • (2004) Life Sci , vol.74 , pp. 3181-3197
    • Pisu, M.G.1    Serra, M.2
  • 90
    • 61349178503 scopus 로고    scopus 로고
    • Simultaneous quantification of GABAergic 3alpha,5alpha/3alpha 5beta neuroactive steroids in human and rat serum
    • Porcu, P., O'Buckley, T. K., Alward, S. E., Marx, C. E., Shampine, L. J., Girdler, S. S., and Morrow, A. L. (2009). Simultaneous quantification of GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in human and rat serum. Steroids 74, 463473.
    • (2009) Steroids , vol.74 , pp. 463-473
    • Porcu, P.1    O'Buckley, T.K.2    Alward, S.E.3    Marx, C.E.4    Shampine, L.J.5    Girdler, S.S.6    Morrow, A.L.7
  • 92
    • 0025882098 scopus 로고
    • Stressinduced elevations of gammaaminobutyric acid type A receptoractive steroids in the rat brain
    • Purdy, R. H., Morrow, A. L., Moore, P. H. Jr., and Paul, S. M. (1991). Stressinduced elevations of gammaaminobutyric acid type A receptoractive steroids in the rat brain. Proc. Natl. Acad. Sci. U.S.A. 88, 45534557.
    • (1991) Proc. Natl. Acad. Sci. U. S. A. , vol.88 , pp. 4553-4557
    • Purdy, R.H.1    Morrow, A.L.2    Moore Jr, P.H.3    Paul, S.M.4
  • 94
  • 95
    • 0042885330 scopus 로고    scopus 로고
    • The physiology of marriage: pathways to health
    • Robles, T. F., and Kiecolt-Glaser, J. K. (2003). The physiology of marriage: pathways to health. Physiol. Behav. 79, 409416.
    • (2003) Physiol. Behav. , vol.79 , pp. 409-416
    • Robles, T.F.1    Kiecolt-Glaser, J.K.2
  • 96
    • 33845731841 scopus 로고    scopus 로고
    • Allopregnanolone reduces immobility in the forced swimming test and increases the firing rate of lateral septal neurons through actions on the GABAA receptor in the rat
    • Rodriguez-Landa, J. F., Contreras, C. M., Bernal-Morales, B., GutierrezGarcia, A. G., and Saavedra, M. (2007). Allopregnanolone reduces immobility in the forced swimming test and increases the firing rate of lateral septal neurons through actions on the GABAA receptor in the rat. J. Psychopharmacol. 21, 7684.
    • (2007) J. Psychopharmacol. , vol.21 , pp. 76-84
    • Rodriguez-Landa, J.F.1    Contreras, C.M.2    Bernal-Morales, B.3    GutierrezGarcia, A.G.4    Saavedra, M.5
  • 98
    • 0030821426 scopus 로고    scopus 로고
    • The neuropsychopharmacological potential of neuroactive steroids
    • Rupprecht, R. (1997). The neuropsychopharmacological potential of neuroactive steroids. J. Psychiatr. Res. 31, 297314.
    • (1997) J. Psychiatr. Res. , vol.31 , pp. 297-314
    • Rupprecht, R.1
  • 99
    • 0012294674 scopus 로고    scopus 로고
    • Behavioral Endocrinology,edsJ.B. Becker,S.M.Breedlove,D.Crews, and M. M. McCarthy (Cambridge, MA: MIT Press)
    • Sapolsky, R. M. (2002). "Endocrinology of the stress-response," in Behavioral Endocrinology,edsJ.B. Becker,S.M.Breedlove,D.Crews, and M. M. McCarthy (Cambridge, MA: MIT Press), 409450
    • (2002) Endocrinology of the stress-response , pp. 409-450
    • Sapolsky, R.M.1
  • 101
    • 0037304804 scopus 로고    scopus 로고
    • Implicit motives and gonadal steroid hormones: effects of menstrual cycle phase, oral contraceptive use, and relationship status
    • Schultheiss, O. C., Dargel, A., and Rohde, W. (2003). Implicit motives and gonadal steroid hormones: effects of menstrual cycle phase, oral contraceptive use, and relationship status. Horm. Behav. 43, 293301.
    • (2003) Horm. Behav. , vol.43 , pp. 293-301
    • Schultheiss, O.C.1    Dargel, A.2    Rohde, W.3
  • 102
    • 8844255375 scopus 로고    scopus 로고
    • Effects of affiliation and power motivation arousal on salivary progesterone and testosterone
    • Schultheiss, O. C., Wirth, M. M., and Stanton, S. J. (2004). Effects of affiliation and power motivation arousal on salivary progesterone and testosterone. Horm. Behav. 46, 592599.
    • (2004) Horm. Behav. , vol.46 , pp. 592-599
    • Schultheiss, O.C.1    Wirth, M.M.2    Stanton, S.J.3
  • 105
    • 0242643502 scopus 로고    scopus 로고
    • Impairments in spatial learning and memory: ethanol, allopregnanolone, and the hippocampus
    • Silvers, J. M., Tokunaga, S., Berry, R. B., White, A. M., and Matthews, D. B. (2003). Impairments in spatial learning and memory: ethanol, allopregnanolone, and the hippocampus. Brain Res. Brain Res. Rev. 43, 275284.
    • (2003) Brain Res. Brain Res. Rev , vol.43 , pp. 275-284
    • Silvers, J.M.1    Tokunaga, S.2    Berry, R.B.3    White, A.M.4    Matthews, D.B.5
  • 107
    • 0344413437 scopus 로고    scopus 로고
    • Administration of progesterone produces mild sedative-like effects in men and women
    • Soderpalm, A. H., Lindsey, S., Purdy, R. H., Hauger, R., and Wit de, H. (2004). Administration of progesterone produces mild sedative-like effects in men and women. Psychoneuroendocrinology 29, 339354.
    • (2004) Psychoneuroendocrinology , vol.29 , pp. 339-354
    • Soderpalm, A.H.1    Lindsey, S.2    Purdy, R.H.3    Hauger, R.4    Wit de, H.5
  • 108
    • 17044444204 scopus 로고    scopus 로고
    • Concentrations of 3 alpha-reduced neuroactive steroids and their precursors in plasma of patients with major depression and after clinical recovery
    • Strohle, A., Romeo, E., Hermann, B., Pasini, A., Spalletta, G., di Michele, F., Holsboer, F., and Rupprecht, R. (1999). Concentrations of 3 alpha-reduced neuroactive steroids and their precursors in plasma of patients with major depression and after clinical recovery. Biol. Psychiatry 45, 274277.
    • (1999) Biol. Psychiatry , vol.45 , pp. 274-277
    • Strohle, A.1    Romeo, E.2    Hermann, B.3    Pasini, A.4    Spalletta, G.5    di Michele, F.6    Holsboer, F.7    Rupprecht, R.8
  • 109
    • 0031962178 scopus 로고    scopus 로고
    • Patients with premenstrual syndrome have a different sensitivity to a neuroactive steroid during the menstrual cycle compared to control subjects
    • Sundstrom, I., Andersson, A., Nyberg, S., Ashbrook, D., Purdy, R. H., and Backstrom, T. (1998). Patients with premenstrual syndrome have a different sensitivity to a neuroactive steroid during the menstrual cycle compared to control subjects. Neuroendocrinology 67, 126138.
    • (1998) Neuroendocrinology , vol.67 , pp. 126-138
    • Sundstrom, I.1    Andersson, A.2    Nyberg, S.3    Ashbrook, D.4    Purdy, R.H.5    Backstrom, T.6
  • 113
    • 0032342065 scopus 로고    scopus 로고
    • Antistress pattern induced by oxytocin
    • Uvnas-Moberg, K. (1998a). Antistress pattern induced by oxytocin. News Physiol. Sci. 13, 2225.
    • (1998) News Physiol. Sci. , vol.13 , pp. 22-25
    • Uvnas-Moberg, K.1
  • 114
    • 0345059241 scopus 로고    scopus 로고
    • Oxytocin may mediate the benefits of positive social interaction and emotions
    • Uvnas-Moberg, K. (1998b). Oxytocin may mediate the benefits of positive social interaction and emotions. Psychoneuroendocrinology 23, 819835.
    • (1998) Psychoneuroendocrinology , vol.23 , pp. 819-835
    • Uvnas-Moberg, K.1
  • 115
    • 0028169479 scopus 로고
    • High doses of oxytocin cause sedation and low doses cause an anxiolytic-like effect in male rats
    • Uvnas-Moberg, K., Ahlenius, S., Hillegaart, V., and Alster, P. (1994). High doses of oxytocin cause sedation and low doses cause an anxiolytic-like effect in male rats. Pharmacol. Biochem. Behav. 49, 101106.
    • (1994) Pharmacol. Biochem. Behav. , vol.49 , pp. 101-106
    • Uvnas-Moberg, K.1    Ahlenius, S.2    Hillegaart, V.3    Alster, P.4
  • 116
    • 33744503400 scopus 로고    scopus 로고
    • Relevance of endogenous 3alpha-reduced neurosteroids to depression and antidepressant action
    • Uzunova, V., Sampson, L., and Uzunov, D. P. (2006). Relevance of endogenous 3alpha-reduced neurosteroids to depression and antidepressant action. Psychopharmacology (Berl.) 186, 351361.
    • (2006) Psychopharmacology (Berl.) , vol.186 , pp. 351-361
    • Uzunova, V.1    Sampson, L.2    Uzunov, D.P.3
  • 117
    • 0032539862 scopus 로고    scopus 로고
    • Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine
    • Uzunova, V., Sheline, Y., Davis, J. M., Rasmusson, A., Uzunov, D. P., Costa, E., and Guidotti, A. (1998). Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine. Proc. Natl. Acad. Sci. U.S.A. 95, 32393244.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 3239-3244
    • Uzunova, V.1    Sheline, Y.2    Davis, J.M.3    Rasmusson, A.4    Uzunov, D.P.5    Costa, E.6    Guidotti, A.7
  • 118
    • 0034544581 scopus 로고    scopus 로고
    • Quantification of neurosteroids in rat plasma and brain following swim stress and allopregnanolone administration using negative chemical ionization gas chromatography/mass spectrometry
    • Vallee, M., Rivera, J. D., Koob, G. F., Purdy, R. H., and Fitzgerald, R. L. (2000). Quantification of neurosteroids in rat plasma and brain following swim stress and allopregnanolone administration using negative chemical ionization gas chromatography/mass spectrometry. Anal. Biochem. 287, 153166.
    • (2000) Anal. Biochem. , vol.287 , pp. 153-166
    • Vallee, M.1    Rivera, J.D.2    Koob, G.F.3    Purdy, R.H.4    Fitzgerald, R.L.5
  • 122
    • 0030785064 scopus 로고    scopus 로고
    • The regional brain distribution of the neurosteroids pregnenolone and pregnenolone sulfate following intravenous infusion
    • Wang, M. D., Wahlstrom, G., and Backstrom, T. (1997). The regional brain distribution of the neurosteroids pregnenolone and pregnenolone sulfate following intravenous infusion. J. Steroid Biochem. Mol. Biol. 62, 299306.
    • (1997) J. Steroid Biochem. Mol. Biol. , vol.62 , pp. 299-306
    • Wang, M.D.1    Wahlstrom, G.2    Backstrom, T.3
  • 123
    • 0025987983 scopus 로고
    • Anxiolytic activity of the progesterone metaboite 5 alpha-pregnan-3 alphao1-20one
    • Wieland, S., Lan, N. C., Mirasedeghi, S., and Gee, K. W. (1991). Anxiolytic activity of the progesterone metaboite 5 alpha-pregnan-3 alphao1-20one. Brain Res. 565, 263268.
    • (1991) Brain Res , vol.565 , pp. 263-268
    • Wieland, S.1    Lan, N.C.2    Mirasedeghi, S.3    Gee, K.W.4
  • 124
    • 84874162197 scopus 로고    scopus 로고
    • Wikipedia. Progesterone. [July 18 2011]
    • Wikipedia. (2011). Progesterone. Available at: http://en.wikipedia.org/ wiki/Progesterone [July 18, 2011].
    • (2011)
  • 125
    • 33751200330 scopus 로고    scopus 로고
    • Relationship between salivary cortisol and progesterone levels in humans
    • Wirth, M. M., Meier, E. A., Fredrickson, B. L., and Schultheiss, O. C. (2007). Relationship between salivary cortisol and progesterone levels in humans. Biol. Psychol. 74, 104107.
    • (2007) Biol. Psychol. , vol.74 , pp. 104-107
    • Wirth, M.M.1    Meier, E.A.2    Fredrickson, B.L.3    Schultheiss, O.C.4
  • 126
    • 33750955315 scopus 로고    scopus 로고
    • Effects of affiliation arousal (hope of closeness) and affiliation stress (fear of rejection) on progesterone and cortisol
    • Wirth, M. M., and Schultheiss, O. C. (2006). Effects of affiliation arousal (hope of closeness) and affiliation stress (fear of rejection) on progesterone and cortisol. Horm. Behav. 50, 786795.
    • (2006) Horm. Behav. , vol.50 , pp. 786-795
    • Wirth, M.M.1    Schultheiss, O.C.2
  • 127
    • 0032986681 scopus 로고    scopus 로고
    • Clinical applications of gas chromatography and gas chromatography-mass spectrometry of steroids
    • Wolthers, B. G., and Kraan, G. P. (1999). Clinical applications of gas chromatography and gas chromatography-mass spectrometry of steroids. J. Chromatogr. A 843, 247274.
    • (1999) J. Chromatogr. A , vol.843 , pp. 247-274
    • Wolthers, B.G.1    Kraan, G.P.2
  • 128
    • 0023872480 scopus 로고
    • Intimacy, power, and psychological well-being in medical students
    • Zeldow, P. B., Daugherty, S. R., and McAdams, D. P. (1988). Intimacy, power, and psychological well-being in medical students. J. Nerv. Ment. Dis. 176, 182.
    • (1988) J. Nerv. Ment. Dis. , vol.176 , pp. 182
    • Zeldow, P.B.1    Daugherty, S.R.2    McAdams, D.P.3
  • 129
    • 0035108694 scopus 로고    scopus 로고
    • Evaluation and comparison of the pharmacokinetic and pharmacodynamic properties of allopregnanolone and pregnanolone at induction of anaesthesia in the male rat
    • Zhu, D., Wang, M. D., Backstrom, T., and Wahlstrom, G. (2001). Evaluation and comparison of the pharmacokinetic and pharmacodynamic properties of allopregnanolone and pregnanolone at induction of anaesthesia in the male rat. Br. J. Anaesth. 86, 403412.
    • (2001) Br. J. Anaesth. , vol.86 , pp. 403-412
    • Zhu, D.1    Wang, M.D.2    Backstrom, T.3    Wahlstrom, G.4
  • 130
    • 0028348176 scopus 로고
    • Reduction of rat pup ultrasonic vocalizations by the neuroactive steroid allopregnanolone
    • Zimmerberg, B., Brunelli, S. A., and Hofer, M. A. (1994). Reduction of rat pup ultrasonic vocalizations by the neuroactive steroid allopregnanolone. Pharmacol. Biochem. Behav. 47, 735738.
    • (1994) Pharmacol. Biochem. Behav. , vol.47 , pp. 735-738
    • Zimmerberg, B.1    Brunelli, S.A.2    Hofer, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.