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Volumn 11, Issue 4, 2012, Pages 482-489

Alzheimer's disease and type 2 diabetes: Exploring the association to obesity and tyrosine hydroxylase

Author keywords

Alzheimer's disease; Dementia; Insulin resistance; Metabolic syndrome; Neurodegeneration; Neuroinflammation; Obesity; Parkinson's disease; Type 2 diabetes mellitus; Tyrosine hydroxylase

Indexed keywords

ADIPOCYTOKINE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; AMYLOID PROTEIN; CYTOKINE; FATTY ACID; GLUCOCORTICOID; GLUCOSE; GLYCOGEN SYNTHASE KINASE; INSULIN; INSULIN RECEPTOR; SOMATOMEDIN C; TAU PROTEIN; TYROSINE 3 MONOOXYGENASE;

EID: 84862523849     PISSN: 18715273     EISSN: 19963181     Source Type: Journal    
DOI: 10.2174/187152712800792767     Document Type: Review
Times cited : (45)

References (111)
  • 1
    • 84855898684 scopus 로고    scopus 로고
    • Acute and chronic animal models for the evaluation of anti-diabetic agents
    • Kumar, S.; Singh, R.; Vasudeva, N.; Sharma, S. Acute and chronic animal models for the evaluation of anti-diabetic agents. Cardiovasc. Diabetol., 2012, 11(1), 9.
    • (2012) Cardiovasc. Diabetol , vol.11 , Issue.1 , pp. 9
    • Kumar, S.1    Singh, R.2    Vasudeva, N.3    Sharma, S.4
  • 2
    • 74049099554 scopus 로고    scopus 로고
    • The relationship between alzheimer's disease and diabetes: Type 3 diabetes?
    • Kroner, Z. The relationship between alzheimer's disease and diabetes: type 3 diabetes? Altern. Med. Rev., 2009, 14(4), 373-379.
    • (2009) Altern. Med. Rev , vol.14 , Issue.4 , pp. 373-379
    • Kroner, Z.1
  • 3
    • 33750510024 scopus 로고    scopus 로고
    • Alzheimer 100 - highlights in the history of Alzheimer research
    • Jellinger, K.A. Alzheimer 100 - highlights in the history of Alzheimer research. J. Neural Transm., 2006, 113, 1603-1623.
    • (2006) J. Neural Transm , vol.113 , pp. 1603-1623
    • Jellinger, K.A.1
  • 5
    • 36448936053 scopus 로고    scopus 로고
    • Common pathological processes in Alzheimer disease and type 2 diabetes. A review
    • Li, L.; Holscher, C. Common pathological processes in Alzheimer disease and type 2 diabetes. A review. Brain Res. Rev., 2007, 56, 384-402.
    • (2007) Brain Res. Rev , vol.56 , pp. 384-402
    • Li, L.1    Holscher, C.2
  • 6
    • 33749030680 scopus 로고    scopus 로고
    • Cardiovascular risk in the spectrum of type 2 diabetes mellitus
    • Ahmed, I.; Goldstein, B.J. Cardiovascular risk in the spectrum of type 2 diabetes mellitus. Mt. Sinai J. Med., 2006, 73, 759-768.
    • (2006) Mt. Sinai J. Med , vol.73 , pp. 759-768
    • Ahmed, I.1    Goldstein, B.J.2
  • 7
    • 51049085039 scopus 로고    scopus 로고
    • Metabolic Syndrome and Alzheimer's disease: A link to a vascular hypothesis?
    • Milionis, H.J.; Florentin, M.; Giannopoulos, S. Metabolic Syndrome and Alzheimer's disease: A link to a vascular hypothesis? CNS Spectr., 2008, 13(7), 606-613.
    • (2008) CNS Spectr , vol.13 , Issue.7 , pp. 606-613
    • Milionis, H.J.1    Florentin, M.2    Giannopoulos, S.3
  • 8
    • 84857747894 scopus 로고    scopus 로고
    • Cpeptide and itscorrelation to parameters of insulin resistance in the metabolic syndrome
    • Banu, S.; Jabir, N.R.; Manjunath, C.N.; Shakil, S.; Kamal, M.A. Cpeptide and itscorrelation to parameters of insulin resistance in the metabolic syndrome. CNS Neurol. Disord. Drug Targets, 2011, 10(8), 921-927.
    • (2011) CNS Neurol. Disord. Drug Targets , vol.10 , Issue.8 , pp. 921-927
    • Banu, S.1    Jabir, N.R.2    Manjunath, C.N.3    Shakil, S.4    Kamal, M.A.5
  • 9
    • 67649682161 scopus 로고    scopus 로고
    • Adiposity, type 2 diabetes and Alzheimer's disease
    • Luchsinger J.A.; Gustafson D.R. Adiposity, type 2 diabetes and Alzheimer's disease. J. Alzheimers Dis., 2009, 16(4), 693-704.
    • (2009) J. Alzheimers Dis , vol.16 , Issue.4 , pp. 693-704
    • Luchsinger, J.A.1    Gustafson, D.R.2
  • 10
    • 33644850953 scopus 로고    scopus 로고
    • Obesity and cardiovascular disease: Pathophysiology, evaluation, and effect of weight loss: An update of the 1997 American Heart Association scientific statement on obesity and heart disease from the Obesity Committee of the Council on Nutrition, PhysicalActivity, and Metabolism
    • Poirier, P.; Giles, T.D.; Bray, G.A.; Hong, Y.; Stern, J.S.; Pi-Sunyer, F.X.; Eckel, R.H. Obesity and cardiovascular disease: Pathophysiology, evaluation, and effect of weight loss: An update of the 1997 American Heart Association scientific statement on obesity and heart disease from the Obesity Committee of the Council on Nutrition, PhysicalActivity, and Metabolism. Circulation, 2006, 113, 898-918.
    • (2006) Circulation , vol.113 , pp. 898-918
    • Poirier, P.1    Giles, T.D.2    Bray, G.A.3    Hong, Y.4    Stern, J.S.5    Pi-Sunyer, F.X.6    Eckel, R.H.7
  • 11
    • 0042484813 scopus 로고    scopus 로고
    • The obesity epidemic: Pathophysiology and consequences of obesity
    • Pi-Sunyer, F.X. The obesity epidemic: Pathophysiology and consequences of obesity. Obes. Res., 2002, 10, 97-104.
    • (2002) Obes. Res. , vol.10 , pp. 97-104
    • Pi-Sunyer, F.X.1
  • 12
    • 70450255115 scopus 로고    scopus 로고
    • Obesity and Alzheimer's disease: A link between body weight and cognitive function in old age
    • Naderali, E.K.; Ratcliffe, S.H.; Dale, M.C. Obesity and Alzheimer's disease: a link between body weight and cognitive function in old age. Am. J. Alzheimers Dis. Other Demen., 2010, 24(6), 445-449.
    • (2010) Am. J. Alzheimers Dis. Other Demen , vol.24 , Issue.6 , pp. 445-449
    • Naderali, E.K.1    Ratcliffe, S.H.2    Dale, M.C.3
  • 13
    • 0034604234 scopus 로고    scopus 로고
    • Pharmacologic therapy for type 2 diabetes mellitus
    • DeFronzo, R.A. Pharmacologic therapy for type 2 diabetes mellitus. Ann. Intern. Med., 2000, 133, 73-74.
    • (2000) Ann. Intern. Med , vol.133 , pp. 73-74
    • Defronzo, R.A.1
  • 14
    • 33745302884 scopus 로고    scopus 로고
    • The Natural course of {beta}- cell function in nondiabetic and diabetic individuals: The insulin resistance atherosclerosis study
    • Festa, A.; Williams, K.; D'Agostino, R. Jr.; Wagenknecht, L.E.; Haffner, S.M. The Natural course of {beta}- cell function in nondiabetic and diabetic individuals: The insulin resistance atherosclerosis study. Diabetes, 2006, 55, 1114-1120.
    • (2006) Diabetes , vol.55 , pp. 1114-1120
    • Festa, A.1    Williams, K.2    D'Agostino Jr., R.3    Wagenknecht, L.E.4    Haffner, S.M.5
  • 15
    • 30944431500 scopus 로고    scopus 로고
    • Insulin resistance, type 2 diabetes mellitus, and cardiovascular disease: The end of the beginning
    • Reaven, G. Insulin resistance, type 2 diabetes mellitus, and cardiovascular disease: the end of the beginning. Circulation, 2005, 112, 3030-3032.
    • (2005) Circulation , vol.112 , pp. 3030-3032
    • Reaven, G.1
  • 17
    • 20544462061 scopus 로고    scopus 로고
    • Obesity in middle age and future risk of dementia: A 27 year longitudinal population based study
    • Whitmer, R.A.; Gunderson, E.P.; Barrett-Connor, E.; Quesenberry, C.P., Jr.; Yaffe, K. Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study. BMJ, 2005, 330(7504), 1360.
    • (2005) BMJ , vol.330 , Issue.7504 , pp. 1360
    • Whitmer, R.A.1    Gunderson, E.P.2    Barrett-Connor, E.3    Quesenberry Jr., C.P.4    Yaffe, K.5
  • 18
    • 79954996833 scopus 로고    scopus 로고
    • Body mass index in midlife and late-life as a risk factor for dementia: A meta-analysis of prospective studies
    • Anstey, K.J.; Cherbuin, N.; Budge, M.; Young, J. Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies. Obes. Rev., 2011, 12(5), e426-e437.
    • (2011) Obes. Rev , vol.12 , Issue.5
    • Anstey, K.J.1    Cherbuin, N.2    Budge, M.3    Young, J.4
  • 19
    • 0027991714 scopus 로고
    • Hyperinsulinaemia and Alzheimer's disease
    • Razay, G.; Wilcock, G.K. Hyperinsulinaemia and Alzheimer's disease. Age Ageing., 1994, 23, 396-399.
    • (1994) Age Ageing , vol.23 , pp. 396-399
    • Razay, G.1    Wilcock, G.K.2
  • 22
    • 2442424380 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function
    • Arvanitakis, Z.; Wilson, R.S.; Bienias, J.L.; Evans, D.A.; Bennett, D.A. Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch. Neurol., 2004, 61, 661-666.
    • (2004) Arch. Neurol , vol.61 , pp. 661-666
    • Arvanitakis, Z.1    Wilson, R.S.2    Bienias, J.L.3    Evans, D.A.4    Bennett, D.A.5
  • 23
    • 0030330547 scopus 로고    scopus 로고
    • The role of the insulin- like growth factors in the central nervous system
    • D'Ercole, A.J.; Ye, P.; Calikoglu, A.S.; Gutierrez-Ospina, G. The role of the insulin- like growth factors in the central nervous system. Mol. Neurobiol., 1996, 13, 227-255.
    • (1996) Mol. Neurobiol , vol.13 , pp. 227-255
    • D'Ercole, A.J.1    Ye, P.2    Calikoglu, A.S.3    Gutierrez-Ospina, G.4
  • 25
    • 79751533413 scopus 로고    scopus 로고
    • Diabetes type II: Risk factor for depression-Parkinson-Alzheimer?
    • Riederer, P.; Bartl J.; Laux, G.; Grunblatt, E. Diabetes type II: risk factor for depression-Parkinson-Alzheimer? Neurotox. Res., 2011, 19, 253-265.
    • (2011) Neurotox. Res , vol.19 , pp. 253-265
    • Riederer, P.1    Bartl, J.2    Laux, G.3    Grunblatt, E.4
  • 26
    • 70349581633 scopus 로고    scopus 로고
    • Insulin resistance and Alzheimer's disease
    • de la Monte, S.M. Insulin resistance and Alzheimer's disease. BMB Rep., 2009, 42, 475-481.
    • (2009) BMB Rep , vol.42 , pp. 475-481
    • de la Monte, S.M.1
  • 28
    • 1242316296 scopus 로고    scopus 로고
    • Insulin and neurodegenerative disease: Shared and specific mechanisms
    • Craft, S.; Watson, G.S. Insulin and neurodegenerative disease: shared and specific mechanisms. Lancet Neurol., 2004, 3, 169-178.
    • (2004) Lancet Neurol , vol.3 , pp. 169-178
    • Craft, S.1    Watson, G.S.2
  • 30
    • 0027437376 scopus 로고
    • Pleiotropic insulin signals are enInsulin resistance and AD Suzanne M. de la Monte 480 BMB reports ttp://bmbreports.org gaged by multisite phosphorylation of IRS-1
    • Sun, X.J.; Crimmins, D.L.; Myers, M.J.; Miralpeix, M.; White, M.F. Pleiotropic insulin signals are enInsulin resistance and AD Suzanne M. de la Monte 480 BMB reports ttp://bmbreports.org gaged by multisite phosphorylation of IRS-1. Mol. Cell. Biol., 1993, 13, 7418-7428.
    • (1993) Mol. Cell. Biol , vol.13 , pp. 7418-7428
    • Sun, X.J.1    Crimmins, D.L.2    Myers, M.J.3    Miralpeix, M.4    White, M.F.5
  • 31
    • 0028018858 scopus 로고
    • The phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1. Stimulation by insulin and inhibition by Wortmannin
    • Lam, K.; Carpenter, C.L.; Ruderman, N.B.; Friel, J.C.; Kelly, K.L. The phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1. Stimulation by insulin and inhibition by Wortmannin. J. Biol. Chem., 1994, 269, 20648-20652.
    • (1994) J. Biol. Chem , vol.269 , pp. 20648-20652
    • Lam, K.1    Carpenter, C.L.2    Ruderman, N.B.3    Friel, J.C.4    Kelly, K.L.5
  • 34
    • 15244350991 scopus 로고    scopus 로고
    • Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: Relevance to Alzheimer's disease
    • de la Monte, S.M.; Wands J.R. Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease. J. Alzheimers Dis., 2005, 7, 45-61.
    • (2005) J. Alzheimers Dis , vol.7 , pp. 45-61
    • de la Monte, S.M.1    Wands, J.R.2
  • 36
    • 33644591150 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: Link to brain reductions in acetylcholine
    • Rivera, E.J.; Goldin, A.; Fulmer, N.; Tavares, R.; Wands, J.R.; de la Monte, S.M. Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine. J. Alzheimers Dis., 2005, 8, 247-268.
    • (2005) J. Alzheimers Dis , vol.8 , pp. 247-268
    • Rivera, E.J.1    Goldin, A.2    Fulmer, N.3    Tavares, R.4    Wands, J.R.5    de la Monte, S.M.6
  • 37
    • 36448936053 scopus 로고    scopus 로고
    • Common pathological processes in Alzheimer disease and type 2 diabetes: A review
    • Li, L., Holscher, C. Common pathological processes in Alzheimer disease and type 2 diabetes: a review. Brain Res. Rev., 2007, 56, 384-402.
    • (2007) Brain Res. Rev , vol.56 , pp. 384-402
    • Li, L.1    Holscher, C.2
  • 38
    • 0142042435 scopus 로고    scopus 로고
    • Transient hypoxia causes Alzheimer-type molecular and biochemical abnormalities in cortical neurons: Potential strategies for neuroprotection
    • Chen, G.J.; Xu, J.; Lahousse, S.A.; Caggiano, N.L.; de la Monte, S.M: Transient hypoxia causes Alzheimer-type molecular and biochemical abnormalities in cortical neurons: potential strategies for neuroprotection. J. Alzheimers Dis., 2003, 5, 209-228.
    • (2003) J. Alzheimers Dis , vol.5 , pp. 209-228
    • Chen, G.J.1    Xu, J.2    Lahousse, S.A.3    Caggiano, N.L.4    de la Monte, S.M.5
  • 39
    • 0345276565 scopus 로고    scopus 로고
    • Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
    • Mandelkow, E.M.; Stamer, K.; Vogel, R.; Thies, E.; Mandelkow, E. Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses. Neurobiol. Aging, 2003, 24, 1079-1085.
    • (2003) Neurobiol. Aging , vol.24 , pp. 1079-1085
    • Mandelkow, E.M.1    Stamer, K.2    Vogel, R.3    Thies, E.4    Mandelkow, E.5
  • 40
    • 84859757164 scopus 로고    scopus 로고
    • Brain insulin resistance accelerates Aß fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes
    • Yamamoto, N.; Matsubara, T.; Sobue, K.; Tanida, M.; Kasahara, R.; Naruse, K.; Taniura, H.; Sato, T.; Suzuki, K. Brain insulin resistance accelerates Aß fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes. J. Neurochem., 2012, 121(4), 619-628.
    • (2012) J. Neurochem , vol.121 , Issue.4 , pp. 619-628
    • Yamamoto, N.1    Matsubara, T.2    Sobue, K.3    Tanida, M.4    Kasahara, R.5    Naruse, K.6    Taniura, H.7    Sato, T.8    Suzuki, K.9
  • 41
    • 17044372334 scopus 로고    scopus 로고
    • Serum or cerebrospinal fluid levels of glyceraldehyde-derived advanced glycation end products (AGEs) may be a promising biomarker for early detection of Alzheimer's disease
    • Yamagishi, S.; Nakamura, K.; Inoue, H.; Kikuchi, S.; Takeuchi, M. Serum or cerebrospinal fluid levels of glyceraldehyde-derived advanced glycation end products (AGEs) may be a promising biomarker for early detection of Alzheimer's disease. Med. Hypotheses, 2005, 64, 1205-1207.
    • (2005) Med. Hypotheses , vol.64 , pp. 1205-1207
    • Yamagishi, S.1    Nakamura, K.2    Inoue, H.3    Kikuchi, S.4    Takeuchi, M.5
  • 43
    • 67650844275 scopus 로고    scopus 로고
    • Epidemiology of Alzheimer's disease: Occurrence, determinants, and strategies toward intervention
    • Qiu, C.; Kivipelto, M.; von Strauss, E. Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention. Dialogues Clin. Neurosci., 2009, 11, 111-128.
    • (2009) Dialogues Clin. Neurosci , vol.11 , pp. 111-128
    • Qiu, C.1    Kivipelto, M.2    von Strauss, E.3
  • 47
    • 42249107660 scopus 로고    scopus 로고
    • Obesity and central obesity as risk factors for incident dementia and its subtypes: A systematic review and meta-analysis
    • Beydoun, M.A.; Beydoun, H.A.; Wang, Y. Obesity and central obesity as risk factors for incident dementia and its subtypes: a systematic review and meta-analysis. Obes. Rev., 2008, 9, 204-218.
    • (2008) Obes. Rev , vol.9 , pp. 204-218
    • Beydoun, M.A.1    Beydoun, H.A.2    Wang, Y.3
  • 48
    • 77957734519 scopus 로고    scopus 로고
    • Obesity and the brain: A possible genetic link
    • Bertram, L.; Heekeren, H. Obesity and the brain: a possible genetic link. Alzheimer's Res. Ther., 2010, 2, 27.
    • (2010) Alzheimer's Res. Ther , vol.2 , pp. 27
    • Bertram, L.1    Heekeren, H.2
  • 49
    • 62449142597 scopus 로고    scopus 로고
    • The role of metabolic disorders in alzheimer disease and vascular dementia
    • Craft, S. The role of metabolic disorders in alzheimer disease and vascular dementia. Arch. Neurol., 2009, 66(3), 300-305.
    • (2009) Arch. Neurol , vol.66 , Issue.3 , pp. 300-305
    • Craft, S.1
  • 50
  • 51
    • 0036712472 scopus 로고    scopus 로고
    • The influence of different fats and fatty acids on obesity, insulin resistance and inflammation
    • Bray, G.A.; Lovejoy, J.C.; Smith, S.R.; DeLany, J.P.; Lefevre, M.; Hwang, D.; Ryan, D.H.; York, D.A. The influence of different fats and fatty acids on obesity, insulin resistance and inflammation. J. Nutr., 2002, 132(9), 2488-2491.
    • (2002) J. Nutr , vol.132 , Issue.9 , pp. 2488-2491
    • Bray, G.A.1    Lovejoy, J.C.2    Smith, S.R.3    Delany, J.P.4    Lefevre, M.5    Hwang, D.6    Ryan, D.H.7    York, D.A.8
  • 53
    • 51749118278 scopus 로고    scopus 로고
    • Distinctive postprandial modulation of beta cell function and insulin sensitivity by dietary fats: Monounsaturated compared with saturated fatty acids
    • Lopez, S.; Bermúdez, B.; Pacheco, Y.M.; Villar, J.; Abia, R.; Muriana, F.J. Distinctive postprandial modulation of beta cell function and insulin sensitivity by dietary fats: monounsaturated compared with saturated fatty acids. Am. J. Clin. Nutr., 2008, 88(3), 638-644.
    • (2008) Am. J. Clin. Nutr , vol.88 , Issue.3 , pp. 638-644
    • Lopez, S.1    Bermúdez, B.2    Pacheco, Y.M.3    Villar, J.4    Abia, R.5    Muriana, F.J.6
  • 54
    • 79951701971 scopus 로고    scopus 로고
    • Targeting TNF-α to elucidate and ameliorate neuroinflammation in neurodegenerative diseases
    • Frankola, K.A.; Greig, N.H.; Luo, W.; Tweedie, D. Targeting TNF-α to elucidate and ameliorate neuroinflammation in neurodegenerative diseases. CNS Neurol. Disord. Drug Targets. 2011, 10(3), 391-403.
    • (2011) CNS Neurol. Disord. Drug Targets , vol.10 , Issue.3 , pp. 391-403
    • Frankola, K.A.1    Greig, N.H.2    Luo, W.3    Tweedie, D.4
  • 55
    • 84856021238 scopus 로고    scopus 로고
    • Amyloid precursor protein and proinflammatory changes are regulated in brain and adipose tissue in a murine model of high fat diet-induced obesity
    • Puig, K.L.; Floden, A.M.; Adhikari, R.; Golovko, M.Y.; Combs, C.K. Amyloid precursor protein and proinflammatory changes are regulated in brain and adipose tissue in a murine model of high fat diet-induced obesity. PLoS ONE, 2012, 7(1), e30378.
    • (2012) PLoS ONE , vol.7 , Issue.1
    • Puig, K.L.1    Floden, A.M.2    Adhikari, R.3    Golovko, M.Y.4    Combs, C.K.5
  • 56
    • 71849089826 scopus 로고    scopus 로고
    • Plasma amyloid- beta peptide levels correlate with adipocyte amyloid precursor protein gene expression in obese individuals
    • Lee, Y.H.; Martin, J.M.; Maple, R.L.; Tharp, W.G.; Pratley, R.E. Plasma amyloid- beta peptide levels correlate with adipocyte amyloid precursor protein gene expression in obese individuals. Neuroendocrinology, 2009, 90, 383-390.
    • (2009) Neuroendocrinology , vol.90 , pp. 383-390
    • Lee, Y.H.1    Martin, J.M.2    Maple, R.L.3    Tharp, W.G.4    Pratley, R.E.5
  • 59
    • 77952507253 scopus 로고    scopus 로고
    • Mattson. Adverse stress, hippocampal networks, and alzheimer's disease
    • Rothman, S.M.; Mark, P. Mattson. Adverse stress, hippocampal networks, and alzheimer's disease. Neuromol. Med., 2010, 12(1), 56-70.
    • (2010) Neuromol. Med , vol.12 , Issue.1 , pp. 56-70
    • Rothman, S.M.1    Mark, P.2
  • 60
    • 77953614413 scopus 로고    scopus 로고
    • Interactions between age, stress and insulin on cognition: Implications for alzheimer's disease
    • Solas, M.; Aisa, B.; Mugueta, M.C.; Del Rio, J.; Tordera, R.M.; Ramirez, M.J. Interactions between age, stress and insulin on cognition: implications for alzheimer's disease. Neuropsychopharmacology, 2010, 35, 1664-1673.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1664-1673
    • Solas, M.1    Aisa, B.2    Mugueta, M.C.3    Del Rio, J.4    Tordera, R.M.5    Ramirez, M.J.6
  • 62
    • 0015434647 scopus 로고
    • Regulation of glucocorticoid release
    • Nelson, D.H. Regulation of glucocorticoid release. Am. J. Med., 1972, 53, 590-594.
    • (1972) Am. J. Med. , vol.53 , pp. 590-594
    • Nelson, D.H.1
  • 63
    • 31444441701 scopus 로고    scopus 로고
    • New approaches to antidepressant drug discovery: Beyond monoamines
    • Berton, O.; Nestler, E.J. New approaches to antidepressant drug discovery: beyond monoamines. Nat. Rev. Neurosci., 2006, 7, 137-151.
    • (2006) Nat. Rev. Neurosci , vol.7 , pp. 137-151
    • Berton, O.1    Nestler, E.J.2
  • 64
    • 33847183893 scopus 로고    scopus 로고
    • Glucocorticoids may initiate Alzheimer's disease: A potential therapeutic role for mifepristone (RU-486)
    • Dhikav, V.; Anand, K.S. Glucocorticoids may initiate Alzheimer's disease: a potential therapeutic role for mifepristone (RU-486). Med. Hypotheses, 2007, 68, 1088-1092.
    • (2007) Med. Hypotheses , vol.68 , pp. 1088-1092
    • Dhikav, V.1    Anand, K.S.2
  • 65
    • 0022250141 scopus 로고
    • Cellular mechanisms in selected states of insulin resistance: Human obesity, glucocorticoid excess and chronic renal failure
    • Amatruda, J.M.; Livingston, J.N.; Lockwood, D.H. Cellular mechanisms in selected states of insulin resistance: human obesity, glucocorticoid excess and chronic renal failure. Diabetes Metab. Rev., 1985, 1, 293-317.
    • (1985) Diabetes Metab. Rev , vol.1 , pp. 293-317
    • Amatruda, J.M.1    Livingston, J.N.2    Lockwood, D.H.3
  • 67
    • 66949152096 scopus 로고    scopus 로고
    • Parkinson's disease
    • Lees, A.J.; Hardy, J.; Revesz, T. Parkinson's disease. Lancet, 2009, 373, 2055-2066.
    • (2009) Lancet , vol.373 , pp. 2055-2066
    • Lees, A.J.1    Hardy, J.2    Revesz, T.3
  • 68
    • 38449091547 scopus 로고    scopus 로고
    • Biochemistry of postmortem brains in Parkinson's disease: Historical overview and future prospects
    • Nagatsu, T.; Sawada, M. Biochemistry of postmortem brains in Parkinson's disease: historical overview and future prospects. J. Neural Transm., 2007, 72, 113-120.
    • (2007) J. Neural Transm , vol.72 , pp. 113-120
    • Nagatsu, T.1    Sawada, M.2
  • 70
    • 0034531475 scopus 로고    scopus 로고
    • The a-Synucleinopathies: Parkinson's disease, dementia with lewy bodies, and multiple system atrophy
    • Spillantini, M.G.; Goedert, M. The a-Synucleinopathies: Parkinson's disease, dementia with lewy bodies, and multiple system atrophy. Ann. NY Acad. Sci., 2000, 920, 16-27.
    • (2000) Ann. NY Acad. Sci , vol.920 , pp. 16-27
    • Spillantini, M.G.1    Goedert, M.2
  • 71
    • 0033919992 scopus 로고    scopus 로고
    • Lewy bodies in Alzheimer's disease: Aneuropathological review of 145 cases using a-Synuclein immunohistochemistry
    • Hamilton, R.L. Lewy bodies in Alzheimer's disease: Aneuropathological review of 145 cases using a-Synuclein immunohistochemistry. Brain Pathol., 2000, 10, 378-384.
    • (2000) Brain Pathol , vol.10 , pp. 378-384
    • Hamilton, R.L.1
  • 73
    • 70450213422 scopus 로고    scopus 로고
    • Peripheral chemo-cytokine profiles in Alzheimer's and Parkinson's diseases
    • Reale, M.; Greig, N.H.; Kamal, M.A. Peripheral chemo-cytokine profiles in Alzheimer's and Parkinson's diseases. Mini Rev. Med. Chem., 2009, 9(10), 1229-1241.
    • (2009) Mini Rev. Med. Chem , vol.9 , Issue.10 , pp. 1229-1241
    • Reale, M.1    Greig, N.H.2    Kamal, M.A.3
  • 75
    • 0028912476 scopus 로고
    • Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development
    • Zhou, Q-Y.; Qualfe, C.J.; Palmiter, R.D. Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development. Nature, 1995, 374, 640-643.
    • (1995) Nature , vol.374 , pp. 640-643
    • Zhou, Q.-Y.1    Qualfe, C.J.2    Palmiter, R.D.3
  • 76
    • 38649121744 scopus 로고    scopus 로고
    • Towards a pathway definition of Parkinson's disease: A complex disorder with links to cancer, diabetes and inflammation
    • Moran, L.B.; Graeber, M.B. Towards a pathway definition of Parkinson's disease: a complex disorder with links to cancer, diabetes and inflammation. Neurogenetics, 2008, 9, 1-13.
    • (2008) Neurogenetics , vol.9 , pp. 1-13
    • Moran, L.B.1    Graeber, M.B.2
  • 78
    • 34447521460 scopus 로고    scopus 로고
    • Human disease classification in the postgenomic era: A complex systems approach to human pathobiology
    • Loscalzo, J.; Kohane, I.; Barabasi, A.L. Human disease classification in the postgenomic era: a complex systems approach to human pathobiology. Mol. Syst. Biol., 2007, 3, 124.
    • (2007) Mol. Syst. Biol , vol.3 , pp. 124
    • Loscalzo, J.1    Kohane, I.2    Barabasi, A.L.3
  • 81
    • 56149110407 scopus 로고    scopus 로고
    • Prospective cohort study of type 2 diabetes and the risk of Parkinson's disease
    • Driver, J.A.; Smith, A.; Buring, J.E.; Gaziano, J.M.; Kurth, T.; Logroscino, G. Prospective cohort study of type 2 diabetes and the risk of Parkinson's disease. Diabetes Care, 2008, 31(10), 2003-2005.
    • (2008) Diabetes Care , vol.31 , Issue.10 , pp. 2003-2005
    • Driver, J.A.1    Smith, A.2    Buring, J.E.3    Gaziano, J.M.4    Kurth, T.5    Logroscino, G.6
  • 88
    • 77449109099 scopus 로고    scopus 로고
    • Age, obesity, and sex effects on insulin sensitivity and skeletal muscle mitochondrial function
    • Karakelides, H.; Irving, B.A.; Short, K.R.; O'Brien, P.; Nair, K.S. Age, obesity, and sex effects on insulin sensitivity and skeletal muscle mitochondrial function. Diabetes, 2010, 59, 89-97.
    • (2010) Diabetes , vol.59 , pp. 89-97
    • Karakelides, H.1    Irving, B.A.2    Short, K.R.3    O'Brien, P.4    Nair, K.S.5
  • 89
  • 90
    • 0033821791 scopus 로고    scopus 로고
    • Tyrosine hydroxylase gene microsatellite polymorphism associated with insulin resistance in depressive disorder
    • Chiba, M.; Suzuki, S.; Hinokio, Y.; Hirai, M.; Satoh, Y.; Tashiro, A.; Utsumi, A.; Awata, T.; Hongo, M.; Toyota, T. Tyrosine hydroxylase gene microsatellite polymorphism associated with insulin resistance in depressive disorder. Metabolism, 2000, 49(9), 1145-1149.
    • (2000) Metabolism , vol.49 , Issue.9 , pp. 1145-1149
    • Chiba, M.1    Suzuki, S.2    Hinokio, Y.3    Hirai, M.4    Satoh, Y.5    Tashiro, A.6    Utsumi, A.7    Awata, T.8    Hongo, M.9    Toyota, T.10
  • 91
    • 66749129095 scopus 로고    scopus 로고
    • Is there an association between the level of highsensitivity C-reactive protein and idiopathic Parkinson's disease? A comparison of Parkinson's disease patients, disease controls and healthy individuals
    • Song, I.U.; Kim, J.S.; Chung, S.W.; Lee, K.S. Is there an association between the level of highsensitivity C-reactive protein and idiopathic Parkinson's disease? A comparison of Parkinson's disease patients, disease controls and healthy individuals. Eur. Neurol., 2009, 62, 99-104.
    • (2009) Eur. Neurol , vol.62 , pp. 99-104
    • Song, I.U.1    Kim, J.S.2    Chung, S.W.3    Lee, K.S.4
  • 99
    • 79955746757 scopus 로고    scopus 로고
    • The cholinergic system and Parkinson disease
    • Bohnen, N.I.; Albin, R.L. The cholinergic system and Parkinson disease. Behav. Brain Res., 2011, 221(2), 564-673.
    • (2011) Behav. Brain Res , vol.221 , Issue.2 , pp. 564-673
    • Bohnen, N.I.1    Albin, R.L.2
  • 100
    • 0029553116 scopus 로고
    • Acetylcholine: A neurotransmitter for learning and memory? Brain Res. Brain Res
    • Blokland, A. Acetylcholine: a neurotransmitter for learning and memory? Brain Res. Brain Res. Rev., 1995, 21, 285-300.
    • (1995) Rev , vol.21 , pp. 285-300
    • Blokland, A.1
  • 101
    • 11144263652 scopus 로고    scopus 로고
    • Different nicotinic acetylcholine receptor subtypes mediating striatal and prefrontal cortical [3H]dopamine release
    • Cao, Y.J.; Surowy, C.S.; Puttfarcken, P.S. Different nicotinic acetylcholine receptor subtypes mediating striatal and prefrontal cortical [3H]dopamine release. Neuropharmacology, 2005, 48, 72-79.
    • (2005) Neuropharmacology , vol.48 , pp. 72-79
    • Cao, Y.J.1    Surowy, C.S.2    Puttfarcken, P.S.3
  • 102
    • 34247849235 scopus 로고    scopus 로고
    • Activation of dopamine D1 receptors enhances cholinergic transmission and social cognition: A parallel dialysis and behavioural study in rats
    • Di Cara, B.; Panayi, F.; Gobert, A.; Dekeyne, A.; Sicard, D.; De Groote, L.; Millan, M.J. Activation of dopamine D1 receptors enhances cholinergic transmission and social cognition: a parallel dialysis and behavioural study in rats. Int. J. Neuropsychopharmacol., 2007, 10, 383-399.
    • (2007) Int. J. Neuropsychopharmacol , vol.10 , pp. 383-399
    • Di Cara, B.1    Panayi, F.2    Gobert, A.3    Dekeyne, A.4    Sicard, D.5    de Groote, L.6    Millan, M.J.7
  • 103
    • 33846841096 scopus 로고    scopus 로고
    • Selective blockade of dopamine D(3) versus D(2) receptors enhances frontocortical cholinergic transmission and social memory in rats: A parallel neurochemical and behavioural analysis
    • Millan, M.J.; Di Cara, B.; Dekeyne, A.; Panayi, F.; De Groote, L.; Sicard, D.; Cistarelli, L.; Billiras, R.; Gobert, A. Selective blockade of dopamine D(3) versus D(2) receptors enhances frontocortical cholinergic transmission and social memory in rats: a parallel neurochemical and behavioural analysis. J. Neurochem., 2007, 100, 1047-1061.
    • (2007) J. Neurochem , vol.100 , pp. 1047-1061
    • Millan, M.J.1    Di Cara, B.2    Dekeyne, A.3    Panayi, F.4    de Groote, L.5    Sicard, D.6    Cistarelli, L.7    Billiras, R.8    Gobert, A.9
  • 104
    • 0028939762 scopus 로고
    • Damage to dopamine systems differs between Parkinson's disease and Alzheimer's disease with parkinsonism
    • Murray, A.M.; Weihmueller, F.B.; Marshall, J.F.; Hurtig, H.I.; Gottleib, G.L.; J Joyce, J.N. Damage to dopamine systems differs between Parkinson's disease and Alzheimer's disease with parkinsonism. Ann. Neurol., 1995, 37, 300-312.
    • (1995) Ann. Neurol , vol.37 , pp. 300-312
    • Murray, A.M.1    Weihmueller, F.B.2    Marshall, J.F.3    Hurtig, H.I.4    Gottleib, G.L.5    Joyce, J.J.N.6
  • 105
    • 0029834869 scopus 로고    scopus 로고
    • Reduced striatal dopamine receptors in Alzheimer's disease: Single photon emission tomography study with the D2 tracer [123I]-IBZM
    • Pizzolato, G.; Chierichetti, F.; Fabbri, M.; Cagnin, A.; Dam, M.; Ferlin, G.; Battistin, L. Reduced striatal dopamine receptors in Alzheimer's disease: single photon emission tomography study with the D2 tracer [123I]-IBZM. Neurology, 1996, 47, 1065-1068.
    • (1996) Neurology , vol.47 , pp. 1065-1068
    • Pizzolato, G.1    Chierichetti, F.2    Fabbri, M.3    Cagnin, A.4    Dam, M.5    Ferlin, G.6    Battistin, L.7
  • 106
    • 0042668338 scopus 로고    scopus 로고
    • Hippocampal dopamine D2 receptors correlate with memory functions in Alzheimer's disease
    • Kemppainen, N.; Laine, M.; Laakso, M.P.; Kaasinen, V.; Nagren, K.; Vahlberg, T. Hippocampal dopamine D2 receptors correlate with memory functions in Alzheimer's disease. Eur. J. Neurosci., 2003, 18, 149-154.
    • (2003) Eur. J. Neurosci , vol.18 , pp. 149-154
    • Kemppainen, N.1    Laine, M.2    Laakso, M.P.3    Kaasinen, V.4    Nagren, K.5    Vahlberg, T.6
  • 108
    • 33846000337 scopus 로고    scopus 로고
    • Immunohistochemical localization of dopamine receptor subtypes (D1R-D5R) in Alzheimer's disease brain
    • Kumar, U.; Patel, S.C. Immunohistochemical localization of dopamine receptor subtypes (D1R-D5R) in Alzheimer's disease brain. Brain Res., 2007, 1131, 187-196.
    • (2007) Brain Res , vol.1131 , pp. 187-196
    • Kumar, U.1    Patel, S.C.2
  • 109
    • 0026503538 scopus 로고
    • Tyrosine hydroxylase-like (TH) immunoreactivity in Parkinson's disease and Alzheimer's disease
    • Torack, R.M.; Morris, J.C. Tyrosine hydroxylase-like (TH) immunoreactivity in Parkinson's disease and Alzheimer's disease. J. Neural Transm. Park. Dis. Dement. Sect., 1992, 4(2), 165-171.
    • (1992) J. Neural Transm. Park. Dis. Dement. Sect , vol.4 , Issue.2 , pp. 165-171
    • Torack, R.M.1    Morris, J.C.2
  • 110
    • 79151475168 scopus 로고    scopus 로고
    • Differential response of the central noradrenergic nervous system to the loss of locus coeruleus neurons in Parkinson's disease and Alzheimer's disease
    • McMillan, P.J.; White, S.S.; Franklin, A.; Greenup, J.L.; Leverenz, J.B.; Raskin, A.M.; Szot, P. Differential response of the central noradrenergic nervous system to the loss of locus coeruleus neurons in Parkinson's disease and Alzheimer's disease. Brain Res., 2011, 10(1373), 240-252.
    • (2011) Brain Res , vol.10 , Issue.1373 , pp. 240-252
    • McMillan, P.J.1    White, S.S.2    Franklin, A.3    Greenup, J.L.4    Leverenz, J.B.5    Raskin, A.M.6    Szot, P.7


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