Progesterone regulation of synaptic transmission and plasticity in rodent hippocampus

Learning and Memory

Volumn 15, Issue 11, 2008, Pages 820-822

  Foy, Michael R ^a   Akopian, Garnik ^b   Thompson, Richard F ^a  

^a LOYOLA MARYMOUNT UNIVERSITY   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; PROGESTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FEMALE; HIPPOCAMPUS; LONG TERM DEPRESSION; LONG TERM POTENTIATION; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTIC TRANSMISSION;

ANIMALS; BIOPHYSICS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; HIPPOCAMPUS; NEURONAL PLASTICITY; OVARIECTOMY; PATCH-CLAMP TECHNIQUES; PROGESTERONE; PROGESTINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SYNAPTIC TRANSMISSION;

EID: 55749094209     PISSN: 10720502     EISSN: 15495485     Source Type: Journal    
DOI: 10.1101/lm.1124708     Document Type: Article

References (12)

1. Edwards, H.E., Epps, T., Carlen, P.L., and MacLusky, N.J. 2000. Progestin receptors mediate progesterone suppression of epileptiform activity in tetanized hippocampal slices in vitro. Neuroscience 101: 895-906.
2. Feng, X.Q., Dong, Y., Fu, Y.M., Zhu, Y.H., Sun, J.L., Wang, Z., Sun, F.Y., and Zheng, P. 2004. Progesterone inhibition of dopamine-induced increase in frequency of spontaneous excitatory postsynaptic currents in rat prelimbic cortical neurons. Neuropharmacology 46: 211-222.
3. Foy, M.R. 2001. 17β-Estradiol: Effect on CA1 hippocampal synaptic plasticity. Neurobiol. Learn. Mem. 76: 239-252.
4. Foy, M.R., Xu, J., Xie, X., Brinton, R.D., Thompson, R.F., and Berger, T.W. 1999. 17β-Estradiol enhances NMDA receptor-mediated EPSPs and long-term potentiation. J. Neurophysiol. 81: 925-929.
5. Herd, M.B., Belelli, D., and Lambert, J.J. 2007. Neurosteroid modulation of synaptic and extrasynaptic GABAA receptors. Pharmacol. Ther. 116: 20-34.
6. Ito, K., Skinkle, K.L., and Hicks, T.P. 1999. Age-dependent, steroid-specific effects of oestrogen on long-term potentiation in rat hippocampal slices. J. Physiol. 515: 209-220.
7. A receptors: Molecular determinants and significance in health and disease. Neurochem. Int. 52: 588-595.
8. Nilsen, J. and Brinton, R.D. 2002. Impact of progestins on estrogen-induced neuroprotection: Synergy by progesterone and 19-norprogesterone and antagonism by medroxyprogesterone acetate. Endocrinology 143: 205-212.
9. Rodgers, A.K. and Falcone, T. 2008. Treatment strategies for endometriosis. Expert Opin. Pharmacother. 9: 243-255.
10. Singh, M. 2006. Progesterone-induced neuroprotection. Endocrine 29: 271-274.
11. Singh, M., Sumien, N., Kyser, C., and Simpkins, J.W. 2008. Estrogens and progesterone as neuroprotectants: What animal models teach us. Front. Biosci. 13: 1083-1089.
12. Suzuki, S., Brown, C.M., and Wise, P.M. 2006. Mechanisms of neuroprotection by estrogen. Endocrine 29: 209-215.