Cellular and functional evidence for a protective action of neurosteroids against vincristine chemotherapy-induced painful neuropathy

Cellular and Molecular Life Sciences

Volumn 67, Issue 17, 2010, Pages 3017-3034

  Meyer, Laurence ^a   Patte Mensah, Christine ^a   Taleb, Omar ^a   Mensah Nyagan, Ayikoe Guy ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Anticancer drug induced neuropathy; Biochemical mechanisms in peripheral nerves; Cell culture; CNPase; Immunohistochemistry; Neurofilament 200 kDa; Protein gene product PGP9.5; Sandwich enzyme immunoassay

Indexed keywords

2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 5ALPHA PREGNANE 3,20 DIONE; FINASTERIDE; NEUROFILAMENT PROTEIN; NEUROSTEROID; PROGESTERONE; VASCULOTROPIN; VINCRISTINE; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ANTINEOPLASTIC AGENT; PROGESTERONE DERIVATIVE; VASCULOTROPIN A;

ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; MALE; MOUSE; NERVE CONDUCTION; NERVE FIBER; NERVE FIBER DEGENERATION; NEUROPATHIC PAIN; NONHUMAN; PAIN THRESHOLD; PROTEIN EXPRESSION; RAT; SKIN CARCINOMA; THERMAL STIMULATION; ANALYSIS OF VARIANCE; ANIMAL; BLOOD; CHEMICALLY INDUCED; DRUG EFFECTS; ELECTROPHYSIOLOGY; ENZYME IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; NEURALGIA; NONPARAMETRIC TEST; PAIN MEASUREMENT; PERIPHERAL NERVE; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

RATTUS;

5-ALPHA-DIHYDROPROGESTERONE; ANALYSIS OF VARIANCE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; ELECTROPHYSIOLOGY; HYDROXYPROGESTERONES; IMMUNOENZYME TECHNIQUES; IMMUNOHISTOCHEMISTRY; MALE; NEURAL CONDUCTION; NEURALGIA; NEUROTRANSMITTER AGENTS; PAIN MEASUREMENT; PERIPHERAL NERVES; RATS; RATS, SPRAGUE-DAWLEY; STATISTICS, NONPARAMETRIC; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VINCRISTINE;

EID: 77956784645     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-010-0372-0     Document Type: Article

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