Neuroprotective effects of progesterone on damage elicited by acute global cerebral ischemia in neurons of the caudate nucleus

Archives of Medical Research

Volumn 33, Issue 1, 2002, Pages 6-14

  Cervantes, Miguel ^a   González Vidal, María ^a   Ruelas, Rodrigo ^a   Moralí, Gabriela ^a   Escobar, Alfonso ^b  

^a INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Cat; Caudate nucleus; Global cerebral ischemia; Neuroprotection; Progesterone

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; PROGESTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; CARDIOPULMONARY INSUFFICIENCY; CAT; CAUDATE NUCLEUS; CONTROLLED STUDY; HEMODYNAMICS; NEUROMUSCULAR BLOCKING; NEUROPROTECTION; NONHUMAN; PYRAMIDAL NERVE CELL; SUBSTANTIA NIGRA;

ANIMALS; BRAIN ISCHEMIA; CATS; CAUDATE NUCLEUS; FEMALE; HEART ARREST; NEURONS; NEUROPROTECTIVE AGENTS; OVARIECTOMY; PROGESTERONE; RANDOM ALLOCATION; SUBSTANTIA NIGRA;

EID: 0036146341     PISSN: 01884409     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0188-4409(01)00347-2     Document Type: Article

References (89)

1. The pathophysiology of brain ischemia
2. Ischaemic brain
3. The pathology of brain ischaemia and possibilities for therapeutic intervention
4. Neurochemical correlates to selective neuronal vulnerability
5. Mechanisms of ischemic cerebral injury
6. The mechanism of ischemia-induced brain cell injury
7. Brain cell death following ischemia and reperfusion; a proposed biochemical sequence
8. 2 deprivation in the central nervous system; on mechanisms of neuronal response, differential sensitivity and injury
9. Mechanism and pathogenesis of ischemia-induced neuronal damage
10. Altered gene expression in cerebral ischemia
11. Brain injury by global ischemia and reperfusion; a theoretical perspective on membrane damage and repair
12. The biochemical basis of cerebral ischemic damage
13. Role of oxidants in ischemic brain damage
14. Gene expression induced by cerebral ischemia; an apoptotic perspective
15. Global cerebral ischemia
16. Pathophysiology of ischemic brain damage
17. Post-ischemic resuscitation of the brain; selective vulnerability versus global resistance
18. Selective vulnerability of the hippocampus to ischemia-reversible and irreversible types of ischemic cell damage
19. Temporal profile of neuronal damage in a model of transient forebrain ischemia
20. Selective neuronal vulnerability; morphological and molecular characteristics
21. Selective neuronal death after transient forebrain ischemia in the Mongolian gerbil; a silver impregnation study
22. Global cerebral ischemia associated with cardiac arrest in the rat. I. Dynamics of early neuronal changes
23. Synaptic release of excitatory aminoacid neurotransmitter mediates anoxic neuronal death
24. Excitatory amino acid neurotoxicity and neurodegenerative disease
25. Zinc and brain injury
26. Effect of ischemia on the in vivo release of striatal dopamine, glutamate, and γ-aminobutyric acid studied by intracerebral microdialysis
27. Increase in extracellular dopamine in the striatum during cerebral ischemia; a study utilizing cerebral microdialysis
28. The non-NMDA antagonists, NBQX and GYKI 52466, protect against cortical and striatal cell loss following transient global ischaemia in the rat
29. Dopamine has inhibitory and accelerating effects on ischemia-induced neuronal cell damage in the rat striatum
30. Amine-mediated toxicity. The effect of dopamine, norepinephrine, 5-hydroxytriptamine, 6-hydroxydopa-mine, ascorbate, glutathion and peroxide on the in vitro activities of creatinine and adenylate kinase in the brain of the rat
31. 3 agonist pramipexole against postischemic or methamphetamine-induced degeneration of nigrostriatal neurons
32. Excitotoxic index-a biochemical marker of selective vulnerability
33. GABA and neuroprotection
34. Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain
35. Protective effect of cyclohexyl adenosine in treatment of cerebral ischemia in gerbils
36. Treatment with an AMPA antagonist 12 hours following severe normothermic forebrain ischemia prevents CA1 neuronal injury
37. Lamotrigine protects hippocampal CA1 neurons from ischemic damage after cardiac arrest
38. Role for γ- aminobutyric acid in selective vulnerability in gerbils
39. Enhancement of GABA neurotransmission after cerebral ischemia in the rat reduces loss of hippocampal CA1 pyramidal cells
40. Gamma-vinyl GABA prevents hippocampal and substantia nigra reticulata damage in repetitive transient forebrain ischemia
41. GABA agonist 'muscimol' is neuroprotective in repetitive transient forebrain ischemia in gerbils
42. Combination therapy protects ischemic brain in rats. A glutamate antagonist plus a γ-aminobutyric acid agonist
43. Clomethiazole protects the brain in transient forebrain ischemia when used up to 4 h after the insult
44. Diazepam given postischemia protects selectively vulnerable neurons in the rat hippocampus and striatum
45. Neuroprotective properties of the benzodiazepine receptor, partial agonist PNU-101017 in the gerbil forebrain ischemia model
46. A receptors
47. Evidence for glutamic acid decarboxylase-containing interneurons in the neostriatum
48. The GABA neurons and their axon terminals in rat corpus striatum as demonstrated by GAD immunocytochemistry
49. Relative sparing of GABAergic interneurons in the striatum of gerbils with ischemia-induced lesions
50. The GABAergic striatonigral neurons of the cat; demonstration by double peroxidase labeling
51. Immunocytochemical demonstration of GABAergic synaptic connections in rat substantia nigra after different lesions of the striatonigral projections
52. Progesterone is neuroprotective after transient middle cerebral artery occlusion in male rats
53. Progesterone; protective effects on the cat hippocampal neuronal damage due to acute global cerebral ischemia
54. Neuroprotective effects of female gonadal steroids in reproductively senescent female rats
55. Neuroprotective effects of progesterone after transient middle cerebral artery occlusion in rat
56. Delayed transneuronal death of substantia nigra neurons prevented by γ-aminobutyric acid agonist
57. Delayed histologic damage and neuron death in the substantia nigra reticulata following transient forebrain ischemia depends on the extent of initial striatal injury
58. Transient forebrain ischemia induces delayed injury in the substantia nigra reticulata; degeneration of GABA neurons, compensatory expression of GAD mRNA
59. Involvement of N-methyl-D-aspartate receptor in the delayed transneuronal regression of substantia nigra neurons in rats
60. Steroid hormone metabolites are barbiturate-like modulators of the GABA receptors
61. Steroid modulation of the chloride ionophore in rat brain; structure-activity requirements, regional dependence and mechanism of action
62. A receptors
63. Steroid anesthetics and naturally occurring analogs modulate the γ-aminobutyric acid receptor complex at a site distinct from barbiturates
64. A receptor
65. A receptor function
66. The neurologic effects of thiopental therapy following experimental cardiac arrest in cats
67. Nimodipine does not improve neurologic outcome after 14 minutes of cardiac arrest in cats
68. Effects of propofol on alterations of multineuronal activity of limbic and mesencephalic structures and neurological deficit elicited by acute global cerebral ischemia
69. Quantitative cytochemistry of RNA in axotomized feline rubral neurons
70. Comparative morphology of the substantia nigra and ventral tegmental area in the monkey, cat and rat
71. Changes in multiunit activity and EEG induced by administration of natural progestins to flaxedil immobilized cats
72. A receptor function
73. Progesterone-induced changes in sleep in male subjects
74. Expression of steroid metabolizing enzymes by aggregating fetal brain cells in culture; a model for developmental regulation of the progesterone 5-alpha-reductase pathways
75. Regional and interspecies differences in brain progesterone metabolism
76. Progesterone administration attenuates excitatory amino acid responses of cerebellar Purkinje cells
77. Progesterone facilitates cognitive recovery and reduces secondary neuronal loss caused by cortical contusion injury in male rats
78. The neurosteroid 3α,5α-THP has antiseizure and possible neuroprotective effects in an animal model of epilepsy
79. Progesterone protects against lipid peroxidation following traumatic brain injury in rats
80. Progesterone and recovery after traumatic brain injury; an overview
81. Progesterone in conjunction with estradiol has neuroprotective effects in an animal model of neurodegeneration
82. Anti-seizure effects of progesterone and 3α,5α-THP in kainic acid and perforant pathway models of epilepsy
83. Gender differences in acute CNS trauma and stroke; neuroprotective effects of estrogen and progesterone
84. Neuroprotective effect of postischemic administration of progesterone in spontaneously hypertensive rats with focal cerebral ischemia
85. Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neurons