-
1
-
-
84864344679
-
Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis
-
doi: 10.1002/hep.25679
-
Au, S. L., Wong, C. C., Lee, J. M., Fan, D. N., Tsang, F. H., Ng, I. O., et al. (2012). Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis. Hepatology 56, 622-631. doi: 10.1002/hep.25679.
-
(2012)
Hepatology
, vol.56
, pp. 622-631
-
-
Au, S.L.1
Wong, C.C.2
Lee, J.M.3
Fan, D.N.4
Tsang, F.H.5
Ng, I.O.6
-
2
-
-
13944260434
-
Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes
-
doi: 10.1261/rna.7240905
-
Baskerville, S., and Bartel, D. P. (2005). Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes. RNA 11, 241-247. doi: 10.1261/rna.7240905.
-
(2005)
RNA
, vol.11
, pp. 241-247
-
-
Baskerville, S.1
Bartel, D.P.2
-
3
-
-
74549118209
-
Accurate classification of non-small cell lung carcinoma using a novel microRNA-based approach
-
doi: 10.1158/1078-0432.CCR-09-2638
-
Bishop, J. A., Benjamin, H., Cholakh, H., Chajut, A., Clark, D. P., and Westra, W. H. (2010). Accurate classification of non-small cell lung carcinoma using a novel microRNA-based approach. Clin. Cancer Res. 16, 610-619. doi: 10.1158/1078-0432.CCR-09-2638.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 610-619
-
-
Bishop, J.A.1
Benjamin, H.2
Cholakh, H.3
Chajut, A.4
Clark, D.P.5
Westra, W.H.6
-
4
-
-
34547458550
-
p53-mediated activation of miRNA34 candidate tumor-suppressor genes
-
doi: 10.1016/j.cub.2007.06.068
-
Bommer, G. T., Gerin, I., Feng, Y., Kaczorowski, A. J., Kuick, R., Love, R. E., et al. (2007). p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr. Biol. 17, 1298-1307. doi: 10.1016/j.cub.2007.06.068.
-
(2007)
Curr. Biol.
, vol.17
, pp. 1298-1307
-
-
Bommer, G.T.1
Gerin, I.2
Feng, Y.3
Kaczorowski, A.J.4
Kuick, R.5
Love, R.E.6
-
5
-
-
58149145653
-
Myeloid cell differentiation arrest by miR-125b-1 in myelodysplastic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation
-
doi: 10.1084/jem.20080285
-
Bousquet, M., Quelen, C., Rosati, R., Mansat-De Mas, V., La Starza, R., Bastard, C., et al. (2008). Myeloid cell differentiation arrest by miR-125b-1 in myelodysplastic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation. J. Exp. Med. 205, 2499-2506. doi: 10.1084/jem.20080285.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2499-2506
-
-
Bousquet, M.1
Quelen, C.2
Rosati, R.3
Mansat-De Mas, V.4
La Starza, R.5
Bastard, C.6
-
6
-
-
40849124009
-
DNA methylation markers and early recurrence in stage I lung cancer
-
doi: 10.1056/NEJMoa0706550
-
Brock, M. V., Hooker, C. M., Ota-Machida, E., Han, Y., Guo, M., Ames, S., et al. (2008). DNA methylation markers and early recurrence in stage I lung cancer. N. Engl. J. Med. 358, 1118-1128. doi: 10.1056/NEJMoa0706550.
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 1118-1128
-
-
Brock, M.V.1
Hooker, C.M.2
Ota-Machida, E.3
Han, Y.4
Guo, M.5
Ames, S.6
-
7
-
-
18744396337
-
Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
doi: 10.1073/pnas.242606799
-
Calin, G. A., Dumitru, C. D., Shimizu, M., Bichi, R., Zupo, S., Noch, E., et al. (2002). Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. U.S.A. 99, 15524-15529. doi: 10.1073/pnas.242606799.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitru, C.D.2
Shimizu, M.3
Bichi, R.4
Zupo, S.5
Noch, E.6
-
8
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
doi: 10.1073/pnas.0307323101
-
Calin, G. A., Sevignani, C., Dumitru, C. D., Hyslop, T., Noch, E., Yendamuri, S., et al. (2004). Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl. Acad. Sci. U.S.A. 101, 2999-3004. doi: 10.1073/pnas.0307323101.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
Hyslop, T.4
Noch, E.5
Yendamuri, S.6
-
9
-
-
1942503942
-
The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3
-
doi: 10.1016/j.gde.2004.02.001
-
Cao, R., and Zhang, Y. (2004). The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3. Curr. Opin. Genet. Dev. 14, 155-164. doi: 10.1016/j.gde.2004.02.001.
-
(2004)
Curr. Opin. Genet. Dev.
, vol.14
, pp. 155-164
-
-
Cao, R.1
Zhang, Y.2
-
10
-
-
77957280345
-
Loss of miR-200c expression induces an aggressive, invasive, and chemoresistant phenotype in non-small cell lung cancer
-
doi: 10.1158/1541-7786.MCR-10-0052
-
Ceppi, P., Mudduluru, G., Kumarswamy, R., Rapa, I., Scagliotti, G. V., Papotti, M., et al. (2010). Loss of miR-200c expression induces an aggressive, invasive, and chemoresistant phenotype in non-small cell lung cancer. Mol. Cancer Res. 8, 1207-1216. doi: 10.1158/1541-7786.MCR-10-0052.
-
(2010)
Mol. Cancer Res.
, vol.8
, pp. 1207-1216
-
-
Ceppi, P.1
Mudduluru, G.2
Kumarswamy, R.3
Rapa, I.4
Scagliotti, G.V.5
Papotti, M.6
-
11
-
-
77954658856
-
A new recurrent translocation t(11;14)(q24;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute lymphoblastic leukemia
-
doi: 10.1038/leu.2010.93
-
Chapiro, E., Russell, L. J., Struski, S., Cave, H., Radford-Weiss, I., Valle, V. D., et al. (2010). A new recurrent translocation t(11;14)(q24;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute lymphoblastic leukemia. Leukemia 24, 1362-1364. doi: 10.1038/leu.2010.93.
-
(2010)
Leukemia
, vol.24
, pp. 1362-1364
-
-
Chapiro, E.1
Russell, L.J.2
Struski, S.3
Cave, H.4
Radford-Weiss, I.5
Valle, V.D.6
-
12
-
-
84882658876
-
Decreased miRNA-148a is associated with lymph node metastasis and poor clinical outcomes and functions as a suppressor of tumor metastasis in non-small cell lung cancer
-
doi: 10.3892/or.2013.2611
-
Chen, Y., Min, L., Zhang, X., Hu, S., Wang, B., Liu, W., et al. (2013). Decreased miRNA-148a is associated with lymph node metastasis and poor clinical outcomes and functions as a suppressor of tumor metastasis in non-small cell lung cancer. Oncol. Rep. 30, 1832-1840. doi: 10.3892/or.2013.2611.
-
(2013)
Oncol. Rep.
, vol.30
, pp. 1832-1840
-
-
Chen, Y.1
Min, L.2
Zhang, X.3
Hu, S.4
Wang, B.5
Liu, W.6
-
13
-
-
84868629163
-
Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells
-
doi: 10.1172/JCI62925
-
Choudhury, Y., Tay, F. C., Lam, D. H., Sandanaraj, E., Tang, C., Ang, B. T., et al. (2012). Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells. J. Clin. Invest. 122, 4059-4076. doi: 10.1172/JCI62925.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 4059-4076
-
-
Choudhury, Y.1
Tay, F.C.2
Lam, D.H.3
Sandanaraj, E.4
Tang, C.5
Ang, B.T.6
-
14
-
-
49749150980
-
A functional screen identifies miR-34a as a candidate neuroblastoma tumor suppressor gene
-
doi: 10.1158/1541-7786.MCR-07-2102
-
Cole, K. A., Attiyeh, E. F., Mosse, Y. P., Laquaglia, M. J., Diskin, S. J., Brodeur, G. M., et al. (2008). A functional screen identifies miR-34a as a candidate neuroblastoma tumor suppressor gene. Mol. Cancer Res. 6, 735-742. doi: 10.1158/1541-7786.MCR-07-2102.
-
(2008)
Mol. Cancer Res.
, vol.6
, pp. 735-742
-
-
Cole, K.A.1
Attiyeh, E.F.2
Mosse, Y.P.3
Laquaglia, M.J.4
Diskin, S.J.5
Brodeur, G.M.6
-
15
-
-
34548803950
-
MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
-
doi: 10.1158/0008-5472.CAN-07-1585
-
Corney, D. C., Flesken-Nikitin, A., Godwin, A. K., Wang, W., and Nikitin, A. Y. (2007). MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res. 67, 8433-8438. doi: 10.1158/0008-5472.CAN-07-1585.
-
(2007)
Cancer Res.
, vol.67
, pp. 8433-8438
-
-
Corney, D.C.1
Flesken-Nikitin, A.2
Godwin, A.K.3
Wang, W.4
Nikitin, A.Y.5
-
16
-
-
48949115082
-
MicroRNA-126 inhibits invasion in non-small cell lung carcinoma cell lines
-
doi: 10.1016/j.bbrc.2008.06.090
-
Crawford, M., Brawner, E., Batte, K., Yu, L., Hunter, M. G., Otterson, G. A., et al. (2008). MicroRNA-126 inhibits invasion in non-small cell lung carcinoma cell lines. Biochem. Biophys. Res. Commun. 373, 607-612. doi: 10.1016/j.bbrc.2008.06.090.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.373
, pp. 607-612
-
-
Crawford, M.1
Brawner, E.2
Batte, K.3
Yu, L.4
Hunter, M.G.5
Otterson, G.A.6
-
17
-
-
79959954361
-
Independent and tissue-specific prognostic impact of miR-126 in nonsmall cell lung cancer: coexpression with vascular endothelial growth factor-A predicts poor survival
-
doi: 10.1002/cncr.25907
-
Donnem, T., Lonvik, K., Eklo, K., Berg, T., Sorbye, S. W., Al-Shibli, K., et al. (2011). Independent and tissue-specific prognostic impact of miR-126 in nonsmall cell lung cancer: coexpression with vascular endothelial growth factor-A predicts poor survival. Cancer 117, 3193-3200. doi: 10.1002/cncr.25907.
-
(2011)
Cancer
, vol.117
, pp. 3193-3200
-
-
Donnem, T.1
Lonvik, K.2
Eklo, K.3
Berg, T.4
Sorbye, S.W.5
Al-Shibli, K.6
-
18
-
-
35649020283
-
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
-
doi: 10.1073/pnas.0707628104
-
Fabbri, M., Garzon, R., Cimmino, A., Liu, Z., Zanesi, N., Callegari, E., et al. (2007). MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc. Natl. Acad. Sci. U.S.A. 104, 15805-15810. doi: 10.1073/pnas.0707628104.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 15805-15810
-
-
Fabbri, M.1
Garzon, R.2
Cimmino, A.3
Liu, Z.4
Zanesi, N.5
Callegari, E.6
-
19
-
-
70849087385
-
miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer
-
doi: 10.1093/carcin/bgp219
-
Gallardo, E., Navarro, A., Vinolas, N., Marrades, R. M., Diaz, T., Gel, B., et al. (2009). miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer. Carcinogenesis 30, 1903-1909. doi: 10.1093/carcin/bgp219.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1903-1909
-
-
Gallardo, E.1
Navarro, A.2
Vinolas, N.3
Marrades, R.M.4
Diaz, T.5
Gel, B.6
-
20
-
-
67650588646
-
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1
-
doi: 10.1182/blood-2008-07-170589
-
Garzon, R., Liu, S., Fabbri, M., Liu, Z., Heaphy, C. E., Callegari, E., et al. (2009). MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood 113, 6411-6418. doi: 10.1182/blood-2008-07-170589.
-
(2009)
Blood
, vol.113
, pp. 6411-6418
-
-
Garzon, R.1
Liu, S.2
Fabbri, M.3
Liu, Z.4
Heaphy, C.E.5
Callegari, E.6
-
21
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
doi: 10.1038/ncb1722
-
Gregory, P. A., Bert, A. G., Paterson, E. L., Barry, S. C., Tsykin, A., Farshid, G., et al. (2008). The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat. Cell Biol. 10, 593-601. doi: 10.1038/ncb1722.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
Barry, S.C.4
Tsykin, A.5
Farshid, G.6
-
22
-
-
9144225636
-
The Microprocessor complex mediates the genesis of microRNAs
-
doi: 10.1038/nature03120
-
Gregory, R. I., Yan, K. P., Amuthan, G., Chendrimada, T., Doratotaj, B., Cooch, N., et al. (2004). The Microprocessor complex mediates the genesis of microRNAs. Nature 432, 235-240. doi: 10.1038/nature03120.
-
(2004)
Nature
, vol.432
, pp. 235-240
-
-
Gregory, R.I.1
Yan, K.P.2
Amuthan, G.3
Chendrimada, T.4
Doratotaj, B.5
Cooch, N.6
-
23
-
-
84861798830
-
Meta-analysis of human lung cancer microRNA expression profiling studies comparing cancer tissues with normal tissues
-
doi: 10.1186/1756-9966-31-54
-
Guan, P., Yin, Z., Li, X., Wu, W., and Zhou, B. (2012). Meta-analysis of human lung cancer microRNA expression profiling studies comparing cancer tissues with normal tissues. J. Exp. Clin. Cancer Res. 31, 54. doi: 10.1186/1756-9966-31-54.
-
(2012)
J. Exp. Clin. Cancer Res.
, vol.31
, pp. 54
-
-
Guan, P.1
Yin, Z.2
Li, X.3
Wu, W.4
Zhou, B.5
-
24
-
-
27544495514
-
A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation
-
doi: 10.1158/0008-5472.CAN-05-2352
-
Hayashita, Y., Osada, H., Tatematsu, Y., Yamada, H., Yanagisawa, K., Tomida, S., et al. (2005). A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res. 65, 9628-9632. doi: 10.1158/0008-5472.CAN-05-2352.
-
(2005)
Cancer Res.
, vol.65
, pp. 9628-9632
-
-
Hayashita, Y.1
Osada, H.2
Tatematsu, Y.3
Yamada, H.4
Yanagisawa, K.5
Tomida, S.6
-
25
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
doi: 10.1038/nature05939
-
He, L., He, X., Lim, L. P., De Stanchina, E., Xuan, Z., Liang, Y., et al. (2007). A microRNA component of the p53 tumour suppressor network. Nature 447, 1130-1134. doi: 10.1038/nature05939.
-
(2007)
Nature
, vol.447
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.P.3
De Stanchina, E.4
Xuan, Z.5
Liang, Y.6
-
26
-
-
20444467290
-
A microRNA polycistron as a potential human oncogene
-
doi: 10.1038/nature03552
-
He, L., Thomson, J. M., Hemann, M. T., Hernando-Monge, E., Mu, D., Goodson, S., et al. (2005). A microRNA polycistron as a potential human oncogene. Nature 435, 828-833. doi: 10.1038/nature03552.
-
(2005)
Nature
, vol.435
, pp. 828-833
-
-
He, L.1
Thomson, J.M.2
Hemann, M.T.3
Hernando-Monge, E.4
Mu, D.5
Goodson, S.6
-
27
-
-
84858239830
-
Genome-wide miRNA expression profiling identifies miR-9-3 and miR-193a as targets for DNA methylation in non-small cell lung cancers
-
doi: 10.1158/1078-0432.CCR-11-2450
-
Heller, G., Weinzierl, M., Noll, C., Babinsky, V., Ziegler, B., Altenberger, C., et al. (2012). Genome-wide miRNA expression profiling identifies miR-9-3 and miR-193a as targets for DNA methylation in non-small cell lung cancers. Clin. Cancer Res. 18, 1619-1629. doi: 10.1158/1078-0432.CCR-11-2450.
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 1619-1629
-
-
Heller, G.1
Weinzierl, M.2
Noll, C.3
Babinsky, V.4
Ziegler, B.5
Altenberger, C.6
-
28
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
doi: 10.1056/NEJMra023075
-
Herman, J. G., and Baylin, S. B. (2003). Gene silencing in cancer in association with promoter hypermethylation. N. Engl. J. Med. 349, 2042-2054. doi: 10.1056/NEJMra023075.
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
29
-
-
74249123570
-
The miR-34 family in cancer and apoptosis
-
doi: 10.1038/cdd.2009.56
-
Hermeking, H. (2010). The miR-34 family in cancer and apoptosis. Cell Death Differ. 17, 193-199. doi: 10.1038/cdd.2009.56.
-
(2010)
Cell Death Differ.
, vol.17
, pp. 193-199
-
-
Hermeking, H.1
-
30
-
-
67749129007
-
DICER1 mutations in familial pleuropulmonary blastoma
-
doi: 10.1126/science.1174334
-
Hill, D. A., Ivanovich, J., Priest, J. R., Gurnett, C. A., Dehner, L. P., Desruisseau, D., et al. (2009). DICER1 mutations in familial pleuropulmonary blastoma. Science 325, 965. doi: 10.1126/science.1174334.
-
(2009)
Science
, vol.325
, pp. 965
-
-
Hill, D.A.1
Ivanovich, J.2
Priest, J.R.3
Gurnett, C.A.4
Dehner, L.P.5
Desruisseau, D.6
-
31
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
doi: 10.1126/science.1062961
-
Hutvagner, G., Mclachlan, J., Pasquinelli, A. E., Balint, E., Tuschl, T., and Zamore, P. D. (2001). A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293, 834-838. doi: 10.1126/science.1062961.
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvagner, G.1
Mclachlan, J.2
Pasquinelli, A.E.3
Balint, E.4
Tuschl, T.5
Zamore, P.D.6
-
32
-
-
84857998198
-
Enhancer of zeste homolog 2 is a novel prognostic biomarker in nonsmall cell lung cancer
-
doi: 10.1002/cncr.26441
-
Huqun, Ishikawa, R., Zhang, J., Miyazawa, H., Goto, Y., Shimizu, Y., et al. (2012). Enhancer of zeste homolog 2 is a novel prognostic biomarker in nonsmall cell lung cancer. Cancer 118, 1599-1606. doi: 10.1002/cncr.26441.
-
(2012)
Cancer
, vol.118
, pp. 1599-1606
-
-
Huqun Ishikawa, R.1
Zhang, J.2
Miyazawa, H.3
Goto, Y.4
Shimizu, Y.5
-
33
-
-
84858777556
-
Epigenetic regulation of miR-212 expression in lung cancer
-
doi: 10.1371/journal.pone.0027722
-
Incoronato, M., Urso, L., Portela, A., Laukkanen, M. O., Soini, Y., Quintavalle, C., et al. (2011). Epigenetic regulation of miR-212 expression in lung cancer. PLoS ONE 6:e27722. doi: 10.1371/journal.pone.0027722 .
-
(2011)
PLoS ONE
, vol.6
-
-
Incoronato, M.1
Urso, L.2
Portela, A.3
Laukkanen, M.O.4
Soini, Y.5
Quintavalle, C.6
-
34
-
-
84859434875
-
Combining microRNA-449a/b with a HDAC inhibitor has a synergistic effect on growth arrest in lung cancer
-
doi: 10.1016/j.lungcan.2011.10.012
-
Jeon, H. S., Lee, S. Y., Lee, E. J., Yun, S. C., Cha, E. J., Choi, E., et al. (2012). Combining microRNA-449a/b with a HDAC inhibitor has a synergistic effect on growth arrest in lung cancer. Lung Cancer 76, 171-176. doi: 10.1016/j.lungcan.2011.10.012.
-
(2012)
Lung Cancer
, vol.76
, pp. 171-176
-
-
Jeon, H.S.1
Lee, S.Y.2
Lee, E.J.3
Yun, S.C.4
Cha, E.J.5
Choi, E.6
-
35
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
doi: 10.1016/j.cell.2005.01.014
-
Johnson, S. M., Grosshans, H., Shingara, J., Byrom, M., Jarvis, R., Cheng, A., et al. (2005). RAS is regulated by the let-7 microRNA family. Cell 120, 635-647. doi: 10.1016/j.cell.2005.01.014.
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
Byrom, M.4
Jarvis, R.5
Cheng, A.6
-
36
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
doi: 10.1038/nrg816
-
Jones, P. A., and Baylin, S. B. (2002). The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3, 415-428. doi: 10.1038/nrg816.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
37
-
-
0035839057
-
The role of DNA methylation in mammalian epigenetics
-
Jones, P. A., and Takai, D. (2001). The role of DNA methylation in mammalian epigenetics. Science 293, 1068-1070.
-
(2001)
Science
, vol.293
, pp. 1068-1070
-
-
Jones, P.A.1
Takai, D.2
-
38
-
-
84866653610
-
let-7b and miR-126 are down-regulated in tumor tissue and correlate with microvessel density and survival outcomes in non-small-cell lung cancer
-
doi: 10.1371/journal.pone.0045577
-
Jusufovic, E., Rijavec, M., Keser, D., Korosec, P., Sodja, E., Iljazovic, E., et al. (2012). let-7b and miR-126 are down-regulated in tumor tissue and correlate with microvessel density and survival outcomes in non-small-cell lung cancer. PLoS ONE 7:e45577. doi: 10.1371/journal.pone.0045577.
-
(2012)
PLoS ONE
, vol.7
-
-
Jusufovic, E.1
Rijavec, M.2
Keser, D.3
Korosec, P.4
Sodja, E.5
Iljazovic, E.6
-
39
-
-
20144373433
-
Reduced expression of Dicer associated with poor prognosis in lung cancer patients
-
Karube, Y., Tanaka, H., Osada, H., Tomida, S., Tatematsu, Y., Yanagisawa, K., et al. (2005). Reduced expression of Dicer associated with poor prognosis in lung cancer patients. Cancer Sci. 96, 111-115.
-
(2005)
Cancer Sci.
, vol.96
, pp. 111-115
-
-
Karube, Y.1
Tanaka, H.2
Osada, H.3
Tomida, S.4
Tatematsu, Y.5
Yanagisawa, K.6
-
40
-
-
52649128795
-
Frequency and fate of microRNA editing in human brain
-
doi: 10.1111/j.1349-7006.2005.00015.x
-
Kawahara, Y., Megraw, M., Kreider, E., Iizasa, H., Valente, L., Hatzigeorgiou, A. G., et al. (2008). Frequency and fate of microRNA editing in human brain. Nucleic Acids Res. 36, 5270-5280. doi: 10.1111/j.1349-7006.2005.00015.x.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 5270-5280
-
-
Kawahara, Y.1
Megraw, M.2
Kreider, E.3
Iizasa, H.4
Valente, L.5
Hatzigeorgiou, A.G.6
-
41
-
-
33847317017
-
Redirection of silencing targets by adenosine-to-inosine editing of miRNAs
-
doi: 10.1093/nar/gkn479
-
Kawahara, Y., Zinshteyn, B., Sethupathy, P., Iizasa, H., Hatzigeorgiou, A. G., and Nishikura, K. (2007). Redirection of silencing targets by adenosine-to-inosine editing of miRNAs. Science 315, 1137-1140. doi: 10.1093/nar/gkn479.
-
(2007)
Science
, vol.315
, pp. 1137-1140
-
-
Kawahara, Y.1
Zinshteyn, B.2
Sethupathy, P.3
Iizasa, H.4
Hatzigeorgiou, A.G.5
Nishikura, K.6
-
42
-
-
81855166206
-
CpG island methylation of microRNAs is associated with tumor size and recurrence of non-small-cell lung cancer
-
doi: 10.1126/science.1138050
-
Kitano, K., Watanabe, K., Emoto, N., Kage, H., Hamano, E., Nagase, T., et al. (2011). CpG island methylation of microRNAs is associated with tumor size and recurrence of non-small-cell lung cancer. Cancer Sci. 102, 2126-2131. doi: 10.1126/science.1138050.
-
(2011)
Cancer Sci.
, vol.102
, pp. 2126-2131
-
-
Kitano, K.1
Watanabe, K.2
Emoto, N.3
Kage, H.4
Hamano, E.5
Nagase, T.6
-
43
-
-
44349131472
-
Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation
-
doi: 10.1111/j.1349-7006.2011.02101.x
-
Kondo, Y., Shen, L., Cheng, A. S., Ahmed, S., Boumber, Y., Charo, C., et al. (2008). Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation. Nat. Genet. 40, 741-750. doi: 10.1111/j.1349-7006.2011.02101.x.
-
(2008)
Nat. Genet.
, vol.40
, pp. 741-750
-
-
Kondo, Y.1
Shen, L.2
Cheng, A.S.3
Ahmed, S.4
Boumber, Y.5
Charo, C.6
-
44
-
-
42049104107
-
Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer
-
doi: 10.1038/ng.159
-
Kozaki, K., Imoto, I., Mogi, S., Omura, K., and Inazawa, J. (2008). Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. Cancer Res. 68, 2094-2105. doi: 10.1038/ng.159.
-
(2008)
Cancer Res.
, vol.68
, pp. 2094-2105
-
-
Kozaki, K.1
Imoto, I.2
Mogi, S.3
Omura, K.4
Inazawa, J.5
-
45
-
-
34247593034
-
Impaired microRNA processing enhances cellular transformation and tumorigenesis
-
doi: 10.1158/0008-5472.CAN-07-5194
-
Kumar, M. S., Lu, J., Mercer, K. L., Golub, T. R., and Jacks, T. (2007). Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat. Genet. 39, 673-677. doi: 10.1158/0008-5472.CAN-07-5194.
-
(2007)
Nat. Genet.
, vol.39
, pp. 673-677
-
-
Kumar, M.S.1
Lu, J.2
Mercer, K.L.3
Golub, T.R.4
Jacks, T.5
-
46
-
-
77949877527
-
Identification of G0S2 as a gene frequently methylated in squamous lung cancer by combination of in silico and experimental approaches
-
doi: 10.1038/ng2003
-
Kusakabe, M., Kutomi, T., Watanabe, K., Emoto, N., Aki, N., Kage, H., et al. (2010). Identification of G0S2 as a gene frequently methylated in squamous lung cancer by combination of in silico and experimental approaches. Int. J. Cancer 126, 1895-1902. doi: 10.1038/ng2003.
-
(2010)
Int. J. Cancer
, vol.126
, pp. 1895-1902
-
-
Kusakabe, M.1
Kutomi, T.2
Watanabe, K.3
Emoto, N.4
Aki, N.5
Kage, H.6
-
47
-
-
0035955374
-
Identification of novel genes coding for small expressed RNAs
-
doi: 10.1126/science.1064921
-
Lagos-Quintana, M., Rauhut, R., Lendeckel, W., and Tuschl, T. (2001). Identification of novel genes coding for small expressed RNAs. Science 294, 853-858. doi: 10.1126/science.1064921.
-
(2001)
Science
, vol.294
, pp. 853-858
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Lendeckel, W.3
Tuschl, T.4
-
48
-
-
0035955361
-
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
-
doi: 10.1126/science.1065062
-
Lau, N. C., Lim, L. P., Weinstein, E. G., and Bartel, D. P. (2001). An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294, 858-862. doi: 10.1126/science.1065062.
-
(2001)
Science
, vol.294
, pp. 858-862
-
-
Lau, N.C.1
Lim, L.P.2
Weinstein, E.G.3
Bartel, D.P.4
-
49
-
-
0035955366
-
An extensive class of small RNAs in Caenorhabditis elegans
-
doi: 10.1126/science.1065329
-
Lee, R. C., and Ambros, V. (2001). An extensive class of small RNAs in Caenorhabditis elegans. Science 294, 862-864. doi: 10.1126/science.1065329.
-
(2001)
Science
, vol.294
, pp. 862-864
-
-
Lee, R.C.1
Ambros, V.2
-
50
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
doi: 10.1016/0092-8674(93)90529-Y
-
Lee, R. C., Feinbaum, R. L., and Ambros, V. (1993). The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75, 843-854. doi: 10.1016/0092-8674(93)90529-Y.
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
51
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
doi: 10.1038/sj.emboj.7600385
-
Lee, Y., Kim, M., Han, J., Yeom, K. H., Lee, S., Baek, S. H., et al. (2004). MicroRNA genes are transcribed by RNA polymerase II. EMBO J. 23, 4051-4060. doi: 10.1038/sj.emboj.7600385.
-
(2004)
EMBO J.
, vol.23
, pp. 4051-4060
-
-
Lee, Y.1
Kim, M.2
Han, J.3
Yeom, K.H.4
Lee, S.5
Baek, S.H.6
-
52
-
-
84862829792
-
The mechanism involved in the loss of PTEN expression in NSCLC tumor cells
-
doi: 10.1016/j.bbrc.2012.01.065
-
Li, G., Zhao, J., Peng, X., Liang, J., Deng, X., and Chen, Y. (2012). The mechanism involved in the loss of PTEN expression in NSCLC tumor cells. Biochem. Biophys. Res. Commun. 418, 547-552. doi: 10.1016/j.bbrc.2012.01.065.
-
(2012)
Biochem. Biophys. Res. Commun.
, vol.418
, pp. 547-552
-
-
Li, G.1
Zhao, J.2
Peng, X.3
Liang, J.4
Deng, X.5
Chen, Y.6
-
53
-
-
84886716989
-
Epigenetic therapy in lung cancer
-
doi: 10.3389/fonc.2013.00135
-
Liu, S. V., Fabbri, M., Gitlitz, B. J., and Laird-Offringa, I. A. (2013). Epigenetic therapy in lung cancer. Front. Oncol. 3:135. doi: 10.3389/fonc.2013.00135.
-
(2013)
Front. Oncol.
, vol.3
, pp. 135
-
-
Liu, S.V.1
Fabbri, M.2
Gitlitz, B.J.3
Laird-Offringa, I.A.4
-
54
-
-
66049084202
-
MiR-126 restoration down-regulate VEGF and inhibit the growth of lung cancer cell lines in vitro and in vivo
-
doi: 10.1016/j.lungcan.2009.01.010
-
Liu, B., Peng, X. C., Zheng, X. L., Wang, J., and Qin, Y. W. (2009). MiR-126 restoration down-regulate VEGF and inhibit the growth of lung cancer cell lines in vitro and in vivo. Lung Cancer 66, 169-175. doi: 10.1016/j.lungcan.2009.01.010.
-
(2009)
Lung Cancer
, vol.66
, pp. 169-175
-
-
Liu, B.1
Peng, X.C.2
Zheng, X.L.3
Wang, J.4
Qin, Y.W.5
-
55
-
-
49749126791
-
Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer
-
doi: 10.4161/cc.7.16.6533
-
Lodygin, D., Tarasov, V., Epanchintsev, A., Berking, C., Knyazeva, T., Korner, H., et al. (2008). Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer. Cell Cycle 7, 2591-2600. doi: 10.4161/cc.7.16.6533.
-
(2008)
Cell Cycle
, vol.7
, pp. 2591-2600
-
-
Lodygin, D.1
Tarasov, V.2
Epanchintsev, A.3
Berking, C.4
Knyazeva, T.5
Korner, H.6
-
56
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
doi: 10.1038/nature03702
-
Lu, J., Getz, G., Miska, E. A., Alvarez-Saavedra, E., Lamb, J., Peck, D., et al. (2005). MicroRNA expression profiles classify human cancers. Nature 435, 834-838. doi: 10.1038/nature03702.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
-
57
-
-
51649083501
-
A microRNA DNA methylation signature for human cancer metastasis
-
doi: 10.1073/pnas.0803055105
-
Lujambio, A., Calin, G. A., Villanueva, A., Ropero, S., Sanchez-Cespedes, M., Blanco, D., et al. (2008). A microRNA DNA methylation signature for human cancer metastasis. Proc. Natl. Acad. Sci. U.S.A. 105, 13556-13561. doi: 10.1073/pnas.0803055105.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 13556-13561
-
-
Lujambio, A.1
Calin, G.A.2
Villanueva, A.3
Ropero, S.4
Sanchez-Cespedes, M.5
Blanco, D.6
-
58
-
-
33847763576
-
Genetic unmasking of an epigenetically silenced microRNA in human cancer cells
-
doi: 10.1158/0008-5472.CAN-06-4218
-
Lujambio, A., Ropero, S., Ballestar, E., Fraga, M. F., Cerrato, C., Setien, F., et al. (2007). Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res. 67, 1424-1429. doi: 10.1158/0008-5472.CAN-06-4218.
-
(2007)
Cancer Res.
, vol.67
, pp. 1424-1429
-
-
Lujambio, A.1
Ropero, S.2
Ballestar, E.3
Fraga, M.F.4
Cerrato, C.5
Setien, F.6
-
59
-
-
0347988235
-
Nuclear export of microRNA precursors
-
doi: 10.1126/science.1090599
-
Lund, E., Guttinger, S., Calado, A., Dahlberg, J. E., and Kutay, U. (2004). Nuclear export of microRNA precursors. Science 303, 95-98. doi: 10.1126/science.1090599.
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Guttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
60
-
-
0035807807
-
Underediting of glutamate receptor GluR-B mRNA in malignant gliomas
-
doi: 10.1073/pnas.251531398
-
Maas, S., Patt, S., Schrey, M., and Rich, A. (2001). Underediting of glutamate receptor GluR-B mRNA in malignant gliomas. Proc. Natl. Acad. Sci. U.S.A. 98, 14687-14692. doi: 10.1073/pnas.251531398.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 14687-14692
-
-
Maas, S.1
Patt, S.2
Schrey, M.3
Rich, A.4
-
61
-
-
68749113985
-
Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
-
doi: 10.1016/j.cell.2009.06.016
-
Mayr, C., and Bartel, D. P. (2009). Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell 138, 673-684. doi: 10.1016/j.cell.2009.06.016.
-
(2009)
Cell
, vol.138
, pp. 673-684
-
-
Mayr, C.1
Bartel, D.P.2
-
62
-
-
33947431322
-
Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
-
doi: 10.1126/science.1137999
-
Mayr, C., Hemann, M. T., and Bartel, D. P. (2007). Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 315, 1576-1579. doi: 10.1126/science.1137999.
-
(2007)
Science
, vol.315
, pp. 1576-1579
-
-
Mayr, C.1
Hemann, M.T.2
Bartel, D.P.3
-
63
-
-
77957940475
-
A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells
-
doi: 10.1016/j.ccr.2010.09.007
-
Melo, S. A., Moutinho, C., Ropero, S., Calin, G. A., Rossi, S., Spizzo, R., et al. (2010). A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells. Cancer Cell 18, 303-315. doi: 10.1016/j.ccr.2010.09.007.
-
(2010)
Cancer Cell
, vol.18
, pp. 303-315
-
-
Melo, S.A.1
Moutinho, C.2
Ropero, S.3
Calin, G.A.4
Rossi, S.5
Spizzo, R.6
-
64
-
-
61349127117
-
A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function
-
doi: 10.1038/ng.317
-
Melo, S. A., Ropero, S., Moutinho, C., Aaltonen, L. A., Yamamoto, H., Calin, G. A., et al. (2009). A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. Nat. Genet. 41, 365-370. doi: 10.1038/ng.317.
-
(2009)
Nat. Genet.
, vol.41
, pp. 365-370
-
-
Melo, S.A.1
Ropero, S.2
Moutinho, C.3
Aaltonen, L.A.4
Yamamoto, H.5
Calin, G.A.6
-
65
-
-
58049213696
-
Dicer, Drosha, and outcomes in patients with ovarian cancer
-
doi: 10.1056/NEJMoa0803785
-
Merritt, W. M., Lin, Y. G., Han, L. Y., Kamat, A. A., Spannuth, W. A., Schmandt, R., et al. (2008). Dicer, Drosha, and outcomes in patients with ovarian cancer. N. Engl. J. Med. 359, 2641-2650. doi: 10.1056/NEJMoa0803785.
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 2641-2650
-
-
Merritt, W.M.1
Lin, Y.G.2
Han, L.Y.3
Kamat, A.A.4
Spannuth, W.A.5
Schmandt, R.6
-
66
-
-
70350596499
-
MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines
-
doi: 10.1016/j.ejca.2009.09.014
-
Muniyappa, M. K., Dowling, P., Henry, M., Meleady, P., Doolan, P., Gammell, P., et al. (2009). MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines. Eur. J. Cancer 45, 3104-3118. doi: 10.1016/j.ejca.2009.09.014.
-
(2009)
Eur. J. Cancer
, vol.45
, pp. 3104-3118
-
-
Muniyappa, M.K.1
Dowling, P.2
Henry, M.3
Meleady, P.4
Doolan, P.5
Gammell, P.6
-
67
-
-
41649091906
-
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
-
doi: 10.1101/gad.1640608
-
Park, S. M., Gaur, A. B., Lengyel, E., and Peter, M. E. (2008). The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev. 22, 894-907. doi: 10.1101/gad.1640608.
-
(2008)
Genes Dev.
, vol.22
, pp. 894-907
-
-
Park, S.M.1
Gaur, A.B.2
Lengyel, E.3
Peter, M.E.4
-
68
-
-
0034597777
-
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
-
doi: 10.1038/35040556
-
Pasquinelli, A. E., Reinhart, B. J., Slack, F., Martindale, M. Q., Kuroda, M. I., Maller, B., et al. (2000). Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature 408, 86-89. doi: 10.1038/35040556.
-
(2000)
Nature
, vol.408
, pp. 86-89
-
-
Pasquinelli, A.E.1
Reinhart, B.J.2
Slack, F.3
Martindale, M.Q.4
Kuroda, M.I.5
Maller, B.6
-
69
-
-
0032481315
-
Inosine exists in mRNA at tissue-specific levels and is most abundant in brain mRNA
-
doi: 10.1093/emboj/17.4.1120
-
Paul, M. S., and Bass, B. L. (1998). Inosine exists in mRNA at tissue-specific levels and is most abundant in brain mRNA. EMBO J. 17, 1120-1127. doi: 10.1093/emboj/17.4.1120.
-
(1998)
EMBO J.
, vol.17
, pp. 1120-1127
-
-
Paul, M.S.1
Bass, B.L.2
-
70
-
-
0034708122
-
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
-
doi: 10.1038/35002607
-
Reinhart, B. J., Slack, F. J., Basson, M., Pasquinelli, A. E., Bettinger, J. C., Rougvie, A. E., et al. (2000). The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 403, 901-906. doi: 10.1038/35002607.
-
(2000)
Nature
, vol.403
, pp. 901-906
-
-
Reinhart, B.J.1
Slack, F.J.2
Basson, M.3
Pasquinelli, A.E.4
Bettinger, J.C.5
Rougvie, A.E.6
-
71
-
-
84885730364
-
Epigenetic therapy in lung cancer-role of microRNAs
-
doi: 10.3389/fonc.2013.00158
-
Rothschild, S. I. (2013). Epigenetic therapy in lung cancer-role of microRNAs. Front. Oncol. 3:158. doi: 10.3389/fonc.2013.00158 .
-
(2013)
Front. Oncol.
, vol.3
, pp. 158
-
-
Rothschild, S.I.1
-
72
-
-
84866541922
-
MicroRNA-29b is involved in the Src-ID1 signaling pathway and is dysregulated in human lung adenocarcinoma
-
doi: 10.1038/onc.2011.578
-
Rothschild, S. I., Tschan, M. P., Federzoni, E. A., Jaggi, R., Fey, M. F., Gugger, M., et al. (2012). MicroRNA-29b is involved in the Src-ID1 signaling pathway and is dysregulated in human lung adenocarcinoma. Oncogene 31, 4221-4232. doi: 10.1038/onc.2011.578.
-
(2012)
Oncogene
, vol.31
, pp. 4221-4232
-
-
Rothschild, S.I.1
Tschan, M.P.2
Federzoni, E.A.3
Jaggi, R.4
Fey, M.F.5
Gugger, M.6
-
73
-
-
33744805399
-
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
-
doi: 10.1016/j.ccr.2006.04.020
-
Saito, Y., Liang, G., Egger, G., Friedman, J. M., Chuang, J. C., Coetzee, G. A., et al. (2006). Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 9, 435-443. doi: 10.1016/j.ccr.2006.04.020.
-
(2006)
Cancer Cell
, vol.9
, pp. 435-443
-
-
Saito, Y.1
Liang, G.2
Egger, G.3
Friedman, J.M.4
Chuang, J.C.5
Coetzee, G.A.6
-
74
-
-
84863360077
-
Preclinical rationale for combining an EGFR antibody with cisplatin/gemcitabine for the treatment of NSCLC
-
Samakoglu, S., Deevi, D. S., Li, H., Wang, S., Murphy, M., Bao, C., et al. (2012). Preclinical rationale for combining an EGFR antibody with cisplatin/gemcitabine for the treatment of NSCLC. Cancer Genomics Proteomics 9, 77-92.
-
(2012)
Cancer Genomics Proteomics
, vol.9
, pp. 77-92
-
-
Samakoglu, S.1
Deevi, D.S.2
Li, H.3
Wang, S.4
Murphy, M.5
Bao, C.6
-
75
-
-
34250196272
-
A second-generation profiling system for quantitative methylation analysis of multiple gene promoters: application to lung cancer
-
doi: 10.1038/sj.onc.1210483
-
Sano, A., Kage, H., Sugimoto, K., Kitagawa, H., Aki, N., Goto, A., et al. (2007). A second-generation profiling system for quantitative methylation analysis of multiple gene promoters: application to lung cancer. Oncogene 26, 6518-6525. doi: 10.1038/sj.onc.1210483.
-
(2007)
Oncogene
, vol.26
, pp. 6518-6525
-
-
Sano, A.1
Kage, H.2
Sugimoto, K.3
Kitagawa, H.4
Aki, N.5
Goto, A.6
-
76
-
-
84864881089
-
Downregulation of miR-126 induces angiogenesis and lymphangiogenesis by activation of VEGF-A in oral cancer
-
doi: 10.1038/bjc.2012.330
-
Sasahira, T., Kurihara, M., Bhawal, U. K., Ueda, N., Shimomoto, T., Yamamoto, K., et al. (2012). Downregulation of miR-126 induces angiogenesis and lymphangiogenesis by activation of VEGF-A in oral cancer. Br. J. Cancer 107, 700-706. doi: 10.1038/bjc.2012.330.
-
(2012)
Br. J. Cancer
, vol.107
, pp. 700-706
-
-
Sasahira, T.1
Kurihara, M.2
Bhawal, U.K.3
Ueda, N.4
Shimomoto, T.5
Yamamoto, K.6
-
77
-
-
84877868296
-
Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells
-
doi: 10.1158/0008-5472.CAN-12-4136
-
Shien, K., Toyooka, S., Yamamoto, H., Soh, J., Jida, M., Thu, K. L., et al. (2013). Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells. Cancer Res. 73, 3051-3061. doi: 10.1158/0008-5472.CAN-12-4136.
-
(2013)
Cancer Res.
, vol.73
, pp. 3051-3061
-
-
Shien, K.1
Toyooka, S.2
Yamamoto, H.3
Soh, J.4
Jida, M.5
Thu, K.L.6
-
78
-
-
0035829691
-
Silencing of HTR1B and reduced expression of EDN1 in human lung cancers, revealed by methylation-sensitive representational difference analysis
-
doi: 10.1038/sj.onc.1204940
-
Takai, D., Yagi, Y., Wakazono, K., Ohishi, N., Morita, Y., Sugimura, T., et al. (2001). Silencing of HTR1B and reduced expression of EDN1 in human lung cancers, revealed by methylation-sensitive representational difference analysis. Oncogene 20, 7505-7513. doi: 10.1038/sj.onc.1204940.
-
(2001)
Oncogene
, vol.20
, pp. 7505-7513
-
-
Takai, D.1
Yagi, Y.2
Wakazono, K.3
Ohishi, N.4
Morita, Y.5
Sugimura, T.6
-
79
-
-
2542626605
-
Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
-
doi: 10.1158/0008-5472.CAN-04-0637
-
Takamizawa, J., Konishi, H., Yanagisawa, K., Tomida, S., Osada, H., Endoh, H., et al. (2004). Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res. 64, 3753-3756. doi: 10.1158/0008-5472.CAN-04-0637.
-
(2004)
Cancer Res.
, vol.64
, pp. 3753-3756
-
-
Takamizawa, J.1
Konishi, H.2
Yanagisawa, K.3
Tomida, S.4
Osada, H.5
Endoh, H.6
-
80
-
-
84858006067
-
Frequent methylation and oncogenic role of microRNA-34b/c in small-cell lung cancer
-
doi: 10.1016/j.lungcan.2011.10.002
-
Tanaka, N., Toyooka, S., Soh, J., Kubo, T., Yamamoto, H., Maki, Y., et al. (2012). Frequent methylation and oncogenic role of microRNA-34b/c in small-cell lung cancer. Lung Cancer 76, 32-38. doi: 10.1016/j.lungcan.2011.10.002.
-
(2012)
Lung Cancer
, vol.76
, pp. 32-38
-
-
Tanaka, N.1
Toyooka, S.2
Soh, J.3
Kubo, T.4
Yamamoto, H.5
Maki, Y.6
-
81
-
-
38049115129
-
Endogenous human microRNAs that suppress breast cancer metastasis
-
doi: 10.1038/nature06487
-
Tavazoie, S. F., Alarcon, C., Oskarsson, T., Padua, D., Wang, Q., Bos, P. D., et al. (2008). Endogenous human microRNAs that suppress breast cancer metastasis. Nature 451, 147-152. doi: 10.1038/nature06487.
-
(2008)
Nature
, vol.451
, pp. 147-152
-
-
Tavazoie, S.F.1
Alarcon, C.2
Oskarsson, T.3
Padua, D.4
Wang, Q.5
Bos, P.D.6
-
82
-
-
79954576652
-
EMT and stem cell-like properties associated with miR-205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells
-
doi: 10.1158/0008-5472.CAN-10-3035
-
Tellez, C. S., Juri, D. E., Do, K., Bernauer, A. M., Thomas, C. L., Damiani, L. A., et al. (2011). EMT and stem cell-like properties associated with miR-205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells. Cancer Res. 71, 3087-3097. doi: 10.1158/0008-5472.CAN-10-3035.
-
(2011)
Cancer Res.
, vol.71
, pp. 3087-3097
-
-
Tellez, C.S.1
Juri, D.E.2
Do, K.3
Bernauer, A.M.4
Thomas, C.L.5
Damiani, L.A.6
-
83
-
-
49249121155
-
Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer
-
doi: 10.1158/0008-5472.CAN-08-0325
-
Toyota, M., Suzuki, H., Sasaki, Y., Maruyama, R., Imai, K., Shinomura, Y., et al. (2008). Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res. 68, 4123-4132. doi: 10.1158/0008-5472.CAN-08-0325.
-
(2008)
Cancer Res.
, vol.68
, pp. 4123-4132
-
-
Toyota, M.1
Suzuki, H.2
Sasaki, Y.3
Maruyama, R.4
Imai, K.5
Shinomura, Y.6
-
84
-
-
58149239686
-
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
-
doi: 10.1126/science.1165395
-
Varambally, S., Cao, Q., Mani, R. S., Shankar, S., Wang, X., Ateeq, B., et al. (2008). Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science 322, 1695-1699. doi: 10.1126/science.1165395.
-
(2008)
Science
, vol.322
, pp. 1695-1699
-
-
Varambally, S.1
Cao, Q.2
Mani, R.S.3
Shankar, S.4
Wang, X.5
Ateeq, B.6
-
85
-
-
33144490646
-
A microRNA expression signature of human solid tumors defines cancer gene targets
-
doi: 10.1073/pnas.0510565103
-
Volinia, S., Calin, G. A., Liu, C. G., Ambs, S., Cimmino, A., Petrocca, F., et al. (2006). A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. U.S.A. 103, 2257-2261. doi: 10.1073/pnas.0510565103.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 2257-2261
-
-
Volinia, S.1
Calin, G.A.2
Liu, C.G.3
Ambs, S.4
Cimmino, A.5
Petrocca, F.6
-
86
-
-
84876099353
-
Meta-analysis of microRNA expression in lung cancer
-
doi: 10.1002/ijc.27981
-
Vosa, U., Vooder, T., Kolde, R., Vilo, J., Metspalu, A., and Annilo, T. (2013). Meta-analysis of microRNA expression in lung cancer. Int. J. Cancer 132, 2884-2893. doi: 10.1002/ijc.27981.
-
(2013)
Int. J. Cancer
, vol.132
, pp. 2884-2893
-
-
Vosa, U.1
Vooder, T.2
Kolde, R.3
Vilo, J.4
Metspalu, A.5
Annilo, T.6
-
87
-
-
48549106378
-
The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis
-
doi: 10.1016/j.devcel.2008.07.002
-
Wang, S., Aurora, A. B., Johnson, B. A., Qi, X., Mcanally, J., Hill, J. A., et al. (2008). The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis. Dev. Cell 15, 261-271. doi: 10.1016/j.devcel.2008.07.002.
-
(2008)
Dev. Cell
, vol.15
, pp. 261-271
-
-
Wang, S.1
Aurora, A.B.2
Johnson, B.A.3
Qi, X.4
Mcanally, J.5
Hill, J.A.6
-
88
-
-
79952331586
-
DNA hypermethylation of microRNA-34b/c has prognostic value for stage non-small cell lung cancer
-
doi: 10.4161/cbt.11.5.14550
-
Wang, Z., Chen, Z., Gao, Y., Li, N., Li, B., Tan, F., et al. (2011). DNA hypermethylation of microRNA-34b/c has prognostic value for stage non-small cell lung cancer. Cancer Biol. Ther. 11, 490-496. doi: 10.4161/cbt.11.5.14550.
-
(2011)
Cancer Biol. Ther.
, vol.11
, pp. 490-496
-
-
Wang, Z.1
Chen, Z.2
Gao, Y.3
Li, N.4
Li, B.5
Tan, F.6
-
89
-
-
84859157171
-
Genome structure-based screening identified epigenetically silenced microRNA associated with invasiveness in non-small-cell lung cancer
-
doi: 10.1002/ijc.26254
-
Watanabe, K., Emoto, N., Hamano, E., Sunohara, M., Kawakami, M., Kage, H., et al. (2012). Genome structure-based screening identified epigenetically silenced microRNA associated with invasiveness in non-small-cell lung cancer. Int. J. Cancer 130, 2580-2590. doi: 10.1002/ijc.26254.
-
(2012)
Int. J. Cancer
, vol.130
, pp. 2580-2590
-
-
Watanabe, K.1
Emoto, N.2
Hamano, E.3
Sunohara, M.4
Kawakami, M.5
Kage, H.6
-
90
-
-
34249812122
-
MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells
-
doi: 10.1038/sj.onc.1210293
-
Welch, C., Chen, Y., and Stallings, R. L. (2007). MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells. Oncogene 26, 5017-5022. doi: 10.1038/sj.onc.1210293.
-
(2007)
Oncogene
, vol.26
, pp. 5017-5022
-
-
Welch, C.1
Chen, Y.2
Stallings, R.L.3
-
91
-
-
0027730383
-
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C
-
doi: 10.1016/0092-8674(93)90530-4
-
Wightman, B., Ha, I., and Ruvkun, G. (1993). Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75, 855-862. doi: 10.1016/0092-8674(93)90530-4.
-
(1993)
elegans. Cell
, vol.75
, pp. 855-862
-
-
Wightman, B.1
Ha, I.2
Ruvkun, G.3
-
92
-
-
84874631435
-
Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis
-
doi: 10.1172/JCI61271
-
Xi, S., Xu, H., Shan, J., Tao, Y., Hong, J. A., Inchauste, S., et al. (2013). Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis. J. Clin. Invest. 123, 1241-1261. doi: 10.1172/JCI61271.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 1241-1261
-
-
Xi, S.1
Xu, H.2
Shan, J.3
Tao, Y.4
Hong, J.A.5
Inchauste, S.6
-
93
-
-
68049117231
-
MicroRNA miR-29 modulates expression of immunoinhibitory molecule B7-H3: potential implications for immune based therapy of human solid tumors
-
doi: 10.1158/0008-5472.CAN-08-4517
-
Xu, H., Cheung, I. Y., Guo, H. F., and Cheung, N. K. (2009). MicroRNA miR-29 modulates expression of immunoinhibitory molecule B7-H3: potential implications for immune based therapy of human solid tumors. Cancer Res. 69, 6275-6281. doi: 10.1158/0008-5472.CAN-08-4517.
-
(2009)
Cancer Res.
, vol.69
, pp. 6275-6281
-
-
Xu, H.1
Cheung, I.Y.2
Guo, H.F.3
Cheung, N.K.4
-
94
-
-
33644819964
-
Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
-
doi: 10.1016/j.ccr.2006.01.025
-
Yanaihara, N., Caplen, N., Bowman, E., Seike, M., Kumamoto, K., Yi, M., et al. (2006). Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 9, 189-198. doi: 10.1016/j.ccr.2006.01.025.
-
(2006)
Cancer Cell
, vol.9
, pp. 189-198
-
-
Yanaihara, N.1
Caplen, N.2
Bowman, E.3
Seike, M.4
Kumamoto, K.5
Yi, M.6
-
95
-
-
37349096992
-
MicroRNA signature predicts survival and relapse in lung cancer
-
doi: 10.1016/j.ccr.2007.12.008
-
Yu, S. L., Chen, H. Y., Chang, G. C., Chen, C. Y., Chen, H. W., Singh, S., et al. (2008). MicroRNA signature predicts survival and relapse in lung cancer. Cancer Cell 13, 48-57. doi: 10.1016/j.ccr.2007.12.008.
-
(2008)
Cancer Cell
, vol.13
, pp. 48-57
-
-
Yu, S.L.1
Chen, H.Y.2
Chang, G.C.3
Chen, C.Y.4
Chen, H.W.5
Singh, S.6
|