Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis

Journal of Clinical Investigation

Volumn 123, Issue 3, 2013, Pages 1241-1261

  Xi, Sichuan ^a   Xu, Hong ^b   Shan, Jigui ^c   Tao, Yongguang ^b   Hong, Julie A ^a   Inchauste, Suzanne ^a   Zhang, Mary ^a   Kunst, Tricia F ^a   Mercedes, Leandro ^a   Schrump, David S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BMI1 PROTEIN; CIGARETTE SMOKE CONDENSATE; DNA; K RAS PROTEIN; MICRORNA; MICRORNA 487B; MYC PROTEIN; UNCLASSIFIED DRUG; WNT5A PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CARCINOGENESIS; CONTROLLED STUDY; DNA METHYLATION; EPIGENETIC REPRESSION; GENE LOCUS; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VIVO STUDY; INTRACELLULAR SIGNALING; LUNG CANCER; METASTASIS POTENTIAL; MOUSE; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM;

ADENOCARCINOMA; ANIMALS; BASE SEQUENCE; BINDING SITES; CELL AGING; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CHROMATIN ASSEMBLY AND DISASSEMBLY; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HISTONES; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, NUDE; MICRORNAS; MIDDLE AGED; NEOPLASM TRANSPLANTATION; POLYCOMB REPRESSIVE COMPLEX 1; POLYCOMB REPRESSIVE COMPLEX 2; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MYC; RAS PROTEINS; RNA INTERFERENCE; SMOKE; SMOKING; TOBACCO; TRANSFORMING GROWTH FACTOR BETA1; WNT PROTEINS;

EID: 84874631435     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI61271     Document Type: Article

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