In vitro characterization of intestinal and hepatic transporters: MRP2

Methods in Pharmacology and Toxicology

Volumn , Issue , 2014, Pages 369-404

  Alluri, Ravindra Varma ^a   Ward, Peter ^b   Kunta, Jeevan R ^b   Ferslew, Brian C ^a   Thakker, Dhiren R ^a   Dallas, Shannon ^b  

^a UNC Hamner Institute for Drug Safety Sciences   (United States)

^b JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

ABCC2; ATPase assays; Caco 2; Drug drug interactions; Efflux; Hepatic MRP2; Intestinal MRP2; MDCKII; Sandwich cultured hepatocytes, MRP2 knockdown; Vesicular transport assays

Indexed keywords

MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2;

ANIMAL CELL; ARTICLE; ATPASE ACTIVITY ASSAY; CELL ASSAY; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG ABSORPTION; DRUG EXCRETION; DRUG TARGETING; GENE SILENCING; HEPATOBILIARY SYSTEM; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE ABSORPTION; INTRACELLULAR TRANSPORT; LIVER CELL CULTURE; MDCK CELL; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FAMILY; WILD TYPE;

EID: 84891905870     PISSN: 15572153     EISSN: 19406053     Source Type: Book Series    
DOI: 10.1007/978-1-62703-742-6_22     Document Type: Article

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