Involvement of multidrug resistance-associated protein 2 (Abcc2) in molecular weight-dependent biliary excretion of β-lactam antibiotics

Drug Metabolism and Disposition

Volumn 36, Issue 6, 2008, Pages 1088-1096

  Kato, Yukio ^a   Takahara, Seiko ^a   Kato, Sayaka ^a   Kubo, Yoshiyuki ^a   Sai, Yoshimichi ^a   Tamai, Ikumi ^a   Yabuuchi, Hikaru ^b   Tsuji, Akira ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b GenoMembrane Inc   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM ANTIBIOTIC; BREAST CANCER RESISTANCE PROTEIN; CEFALEXIN; CEFAMANDOLE; CEFAZOLIN; CEFBUPERAZONE; CEFDINIR; CEFIXIME; CEFMETAZOLE; CEFOPERAZONE; CEFOTETAN; CEFOTIAM; CEFPIRAMIDE; CEFTEZOLE; CEFTRIAXONE; CEFUROXIME; MULTIDRUG RESISTANCE PROTEIN 2;

ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BILIARY EXCRETION; CONTROLLED STUDY; DRUG CLEARANCE; DRUG POTENCY; DRUG TRANSPORT; GLOMERULUS FILTRATION RATE; HYPERBILIRUBINEMIA; MALE; MEMBRANE TRANSPORT; MEMBRANE VESICLE; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTI-BACTERIAL AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; BILE; CELL MEMBRANE PERMEABILITY; CEPHALOSPORINS; HUMANS; HYPERBILIRUBINEMIA; KIDNEY; LIVER; MALE; MOLECULAR WEIGHT; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 44149128448     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.107.019125     Document Type: Article

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