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Volumn 14, Issue 10, 2013, Pages 5543-5552

Dietary non-nutritive factors in targeting of regulatory molecules in colorectal cancer: An update

Author keywords

Colon cancer; COX 2; Notch; Nrf2; catenin

Indexed keywords

ANIMAL; COLORECTAL TUMOR; DIET; GENETICS; HUMAN; METABOLISM; PROCEDURES; SIGNAL TRANSDUCTION;

EID: 84890478128     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2013.14.10.5543     Document Type: Review
Times cited : (31)

References (141)
  • 1
    • 67649424560 scopus 로고    scopus 로고
    • p21 in cancer: intricate networks and multiple activities
    • Abbas T, Dutta A (2009). p21 in cancer: intricate networks and multiple activities. Nat Rev Cancer, 9, 400-14.
    • (2009) Nat Rev Cancer , vol.9 , pp. 400-414
    • Abbas, T.1    Dutta, A.2
  • 2
    • 0030978351 scopus 로고    scopus 로고
    • β-Catenin is a target for the ubiquitin-proteasome pathway
    • Aberle H, Bauer A, Stappert J, et al (1997). β-Catenin is a target for the ubiquitin-proteasome pathway. EMBO J, 16, 3797-804.
    • (1997) EMBO J , vol.16 , pp. 3797-3804
    • Aberle, H.1    Bauer, A.2    Stappert, J.3
  • 4
    • 84884210008 scopus 로고    scopus 로고
    • Effect of dietary caraway essential oils on expression of β-catenin during 1, 2-dimethylhydrazine-induced colonic carcinogenesis
    • Allameh A, Dadkhah A, Rahbarizadeh F, et al (2012). Effect of dietary caraway essential oils on expression of β-catenin during 1, 2-dimethylhydrazine-induced colonic carcinogenesis. J Nat Med, 67, 690-7.
    • (2012) J Nat Med , vol.67 , pp. 690-697
    • Allameh, A.1    Dadkhah, A.2    Rahbarizadeh, F.3
  • 5
    • 0031984809 scopus 로고    scopus 로고
    • Frequent nitric oxide synthase-2 expression in human colon adenomas: Implication for tumor angiogenesis and colon cancer progression
    • Ambs S, Merriam WG, Bennett WP, et al (1998). Frequent nitric oxide synthase-2 expression in human colon adenomas: Implication for tumor angiogenesis and colon cancer progression. Cancer Res, 58, 334-41.
    • (1998) Cancer Res , vol.58 , pp. 334-341
    • Ambs, S.1    Merriam, W.G.2    Bennett, W.P.3
  • 6
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: cell fate control and signal integration in development
    • Artavanis-Tsakonas S, Rand MD, Lake RJ (1999). Notch signaling: cell fate control and signal integration in development. Science, 284, 770-6.
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 7
    • 84866396886 scopus 로고    scopus 로고
    • Dietary administration od scallion extract effectively inhibits colorectal tumor growth: cellular and molecular mechanisms in mice
    • Arulselvan P, Wen CC, Lan CW, et al (2012). Dietary administration od scallion extract effectively inhibits colorectal tumor growth: cellular and molecular mechanisms in mice. PLoS One, 7, 44658.
    • (2012) PLoS One , vol.7 , pp. 44658
    • Arulselvan, P.1    Wen, C.C.2    Lan, C.W.3
  • 8
    • 54149090600 scopus 로고    scopus 로고
    • Protective role of Luteolin on the status of lipid peroxidation and antioxidant defense against Azoxymethane-induced experimental colon carcinogenesis
    • Ashokkumar P, Sudhandiran G (2008). Protective role of Luteolin on the status of lipid peroxidation and antioxidant defense against Azoxymethane-induced experimental colon carcinogenesis. Biomed Pharmacother, 62, 590-7.
    • (2008) Biomed Pharmacother , vol.62 , pp. 590-597
    • Ashokkumar, P.1    Sudhandiran, G.2
  • 9
    • 79957473480 scopus 로고    scopus 로고
    • Luteolin inhibits cell proliferation during Azoxymethane-induced experimental colon carcinogenesis via Wnt/β-catenin pathway
    • Ashokkumar P, Sudhandiran G (2011). Luteolin inhibits cell proliferation during Azoxymethane-induced experimental colon carcinogenesis via Wnt/β-catenin pathway. Invest New Drugs, 29, 273-84.
    • (2011) Invest New Drugs , vol.29 , pp. 273-284
    • Ashokkumar, P.1    Sudhandiran, G.2
  • 10
    • 0037376416 scopus 로고    scopus 로고
    • An overview of the notch signalling pathway
    • Baron M (2003). An overview of the notch signalling pathway. Semin Cell DevBiol, 14, 113-9.
    • (2003) Semin Cell DevBiol , vol.14 , pp. 113-119
    • Baron, M.1
  • 11
    • 77958010589 scopus 로고    scopus 로고
    • Allicin purified from fresh garlic cloves induces apoptosis in colon cancer cells via Nrf2
    • Bat-Chen W, Golan T, Peri I, et al (2010). Allicin purified from fresh garlic cloves induces apoptosis in colon cancer cells via Nrf2. Nutr Cancer, 62, 947-57.
    • (2010) Nutr Cancer , vol.62 , pp. 947-957
    • Bat-Chen, W.1    Golan, T.2    Peri, I.3
  • 12
    • 0029781509 scopus 로고    scopus 로고
    • Functional interaction of β-catenin with the transcription factor LEF-1
    • Behrens J, Kries JV, Kuhl M, et al (1996). Functional interaction of β-catenin with the transcription factor LEF-1. Nature, 382, 638-42.
    • (1996) Nature , vol.382 , pp. 638-642
    • Behrens, J.1    Kries, J.V.2    Kuhl, M.3
  • 13
    • 0027411316 scopus 로고
    • Dietary factors related to colorectalneoplasms
    • Burnstein MJ (1993). Dietary factors related to colorectalneoplasms. Surg Clin North America, 73, 13-29.
    • (1993) Surg Clin North America , vol.73 , pp. 13-29
    • Burnstein, M.J.1
  • 14
    • 0034672595 scopus 로고    scopus 로고
    • Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein
    • Chan JY, Kwong M (2000). Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein. Biochim Biophys Acta, 1517, 19-26.
    • (2000) Biochim Biophys Acta , vol.1517 , pp. 19-26
    • Chan, J.Y.1    Kwong, M.2
  • 15
    • 0035839554 scopus 로고    scopus 로고
    • Kruppel-like factor 4 (gut-enriched Kruppel-like factor)inhibits cell proliferation by blocking G1/S progression of the cell cycle
    • Chen X, Johns DC, Geiman DE, et al (2001). Kruppel-like factor 4 (gut-enriched Kruppel-like factor)inhibits cell proliferation by blocking G1/S progression of the cell cycle. J Biol Chem, 276, 30423-8.
    • (2001) J Biol Chem , vol.276 , pp. 30423-30428
    • Chen, X.1    Johns, D.C.2    Geiman, D.E.3
  • 16
    • 84863529339 scopus 로고    scopus 로고
    • The natural alkaloid berberine targets multiple pathways to induce cell death in cultured human colon cancer cells
    • Chidambara Murthy KN, Jayaprakasha GK, Patil BS (2012). The natural alkaloid berberine targets multiple pathways to induce cell death in cultured human colon cancer cells. Eur J Pharmacol, 688, 14-21.
    • (2012) Eur J Pharmacol , vol.688 , pp. 14-21
    • Chidambara Murthy, K.N.1    Jayaprakasha, G.K.2    Patil, B.S.3
  • 17
    • 84859388853 scopus 로고    scopus 로고
    • Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice
    • Chiou YS, Ma NJ, Sang S, et al (2012).Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice. J Agric Food Chem, 60, 3441-51.
    • (2012) J Agric Food Chem , vol.60 , pp. 3441-3451
    • Chiou, Y.S.1    Ma, N.J.2    Sang, S.3
  • 18
    • 79952756381 scopus 로고    scopus 로고
    • Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM)-induced colon tumorigenesis via activation of the NF-E2-related factor 2 (Nrf2)-mediated antioxidant signaling pathway
    • Chiou YS, Tsai ML, Nagabhushanam K, et al (2011). Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM)-induced colon tumorigenesis via activation of the NF-E2-related factor 2 (Nrf2)-mediated antioxidant signaling pathway. J Agric Food Chem, 59, 2725-33.
    • (2011) J Agric Food Chem , vol.59 , pp. 2725-2733
    • Chiou, Y.S.1    Tsai, M.L.2    Nagabhushanam, K.3
  • 19
    • 0141629373 scopus 로고    scopus 로고
    • Cyclooxygenase 2 inhibition in colorectal cancer therapy
    • Church RD, Fleshman JW, McLeod HL (2003). Cyclooxygenase 2 inhibition in colorectal cancer therapy. Br J Surg, 90, 1055-7.
    • (2003) Br J Surg , vol.90 , pp. 1055-1057
    • Church, R.D.1    Fleshman, J.W.2    McLeod, H.L.3
  • 20
    • 0037372178 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase expression in human colorectal cancer
    • Cianchi F, Cortesini C, Fantappie O, Messerini L (2003). Inducible nitric oxide synthase expression in human colorectal cancer. Am J Pathol, 162, 793.
    • (2003) Am J Pathol , vol.162 , pp. 793
    • Cianchi, F.1    Cortesini, C.2    Fantappie, O.3    Messerini, L.4
  • 21
    • 84880442189 scopus 로고    scopus 로고
    • EpicatechinGallate induces cell death via p53 activation and stimulation of p38 and JNK in human colon cancer SW480 Cells
    • Cordero-Herrera I, Martín MA, Bravo L, et al (2013). EpicatechinGallate induces cell death via p53 activation and stimulation of p38 and JNK in human colon cancer SW480 Cells. Nutr Cancer, 65, 718-28.
    • (2013) Nutr Cancer , vol.65 , pp. 718-728
    • Cordero-Herrera, I.1    Martín, M.A.2    Bravo, L.3
  • 22
    • 0034532675 scopus 로고    scopus 로고
    • The biology of the mammalian Kruppel-like family of transcription factors
    • Dang DT, Pevsner J, Yang VW (2000). The biology of the mammalian Kruppel-like family of transcription factors. Int J Biochem Cell Biol, 32, 1103-21.
    • (2000) Int J Biochem Cell Biol , vol.32 , pp. 1103-1121
    • Dang, D.T.1    Pevsner, J.2    Yang, V.W.3
  • 23
    • 0032521538 scopus 로고    scopus 로고
    • High frequency of β-catenin (Ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rats
    • Dashwood RH, Suzui M, Nakagama H, et al (1998). High frequency of β-catenin (Ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rats. Cancer Res, 58, 1127-9.
    • (1998) Cancer Res , vol.58 , pp. 1127-1129
    • Dashwood, R.H.1    Suzui, M.2    Nakagama, H.3
  • 25
    • 84880081054 scopus 로고    scopus 로고
    • Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation
    • Derry MM, Raina K, Balaiya V, et al (2013). Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation. Cancer Prev Res (Phila), 6, 625-33.
    • (2013) Cancer Prev Res (Phila) , vol.6 , pp. 625-633
    • Derry, M.M.1    Raina, K.2    Balaiya, V.3
  • 27
    • 0344629380 scopus 로고    scopus 로고
    • Bcl- 2 family members as sentinels of cellular integrity and role of mitochondrial intermembrane space proteins in apoptotic cell death
    • Festjens N, van Gurp M, van Loo G, et al (2004). Bcl- 2 family members as sentinels of cellular integrity and role of mitochondrial intermembrane space proteins in apoptotic cell death. Acta Haematol, 111, 7-27.
    • (2004) Acta Haematol , vol.111 , pp. 7-27
    • Festjens, N.1    van Gurp, M.2    van Loo, G.3
  • 28
    • 0023554422 scopus 로고
    • Effects of chronic dietary ethanol on the in vivo and in vitro metabolism of methylazoxymethanol and methylazoxymethanol-induced DNA methylation in the rat colon and liver
    • Fiala ES, Sohn OS, Hamilton SR (1987).Effects of chronic dietary ethanol on the in vivo and in vitro metabolism of methylazoxymethanol and methylazoxymethanol-induced DNA methylation in the rat colon and liver. Cancer Res, 47, 5939-43.
    • (1987) Cancer Res , vol.47 , pp. 5939-5943
    • Fiala, E.S.1    Sohn, O.S.2    Hamilton, S.R.3
  • 29
    • 9244232804 scopus 로고    scopus 로고
    • Nitric oxide induced p53 accumulation and regulation of iNOS expression by wild type p53
    • Forrester K, Ambs S, Lupold E, et al (1996). Nitric oxide induced p53 accumulation and regulation of iNOS expression by wild type p53. Proc Natl Acad Sci USA, 93, 2441-7.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2441-2447
    • Forrester, K.1    Ambs, S.2    Lupold, E.3
  • 30
    • 11144264663 scopus 로고    scopus 로고
    • BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase
    • Furukawa M, Xiong Y (2005). BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase. Mol Cell Biol, 25, 162-71.
    • (2005) Mol Cell Biol , vol.25 , pp. 162-171
    • Furukawa, M.1    Xiong, Y.2
  • 31
    • 57749110620 scopus 로고    scopus 로고
    • Notch inhibits expression of the Krüppel-like factor 4 tumor suppressor in the intestinal epithelium
    • Ghaleb AM, Aggarwal G, Bialkoska AB, et al (2008). Notch inhibits expression of the Krüppel-like factor 4 tumor suppressor in the intestinal epithelium. Mol Cancer Res, 6, 1920-7.
    • (2008) Mol Cancer Res , vol.6 , pp. 1920-1927
    • Ghaleb, A.M.1    Aggarwal, G.2    Bialkoska, A.B.3
  • 32
    • 34547642699 scopus 로고    scopus 로고
    • Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis
    • Ghaleb AM, McConnell BB, Nandan MO, et al (2007). Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis. Cancer Res, 67, 7147-54.
    • (2007) Cancer Res , vol.67 , pp. 7147-7154
    • Ghaleb, A.M.1    McConnell, B.B.2    Nandan, M.O.3
  • 33
    • 0029150934 scopus 로고
    • Aspirin and the risk of colorectal cancer in women
    • Giovannucci E, Egan KM, Hunter DJ, et al (1995). Aspirin and the risk of colorectal cancer in women. N Engl J Med, 333, 609-14.
    • (1995) N Engl J Med , vol.333 , pp. 609-614
    • Giovannucci, E.1    Egan, K.M.2    Hunter, D.J.3
  • 34
    • 78650861188 scopus 로고    scopus 로고
    • Effects of the black tea polyphenol theaflavin-2 on apoptotic and inflammatory pathways in vitro and in vivo
    • Gosslau A, En Jao DL, Huang MT, et al (2011). Effects of the black tea polyphenol theaflavin-2 on apoptotic and inflammatory pathways in vitro and in vivo. Mol Nutr Food Res, 55, 198-208.
    • (2011) Mol Nutr Food Res , vol.55 , pp. 198-208
    • Gosslau, A.1    En Jao, D.L.2    Huang, M.T.3
  • 36
    • 17444423289 scopus 로고    scopus 로고
    • Wnt signaling in the intestinal epithelium: from endoderm to cancer
    • GregorieffA, Clevers H (2005). Wnt signaling in the intestinal epithelium: from endoderm to cancer. Gene Dev, 19, 877-90.
    • (2005) Gene Dev , vol.19 , pp. 877-890
    • Gregorieff, A.1    Clevers, H.2
  • 37
    • 84884252482 scopus 로고    scopus 로고
    • Galangin induces human colon cancer cell death via the mitochondrial dysfunction and caspase-dependent pathway
    • Ha TK, Kim ME, Yoon JH, et al (2013). Galangin induces human colon cancer cell death via the mitochondrial dysfunction and caspase-dependent pathway. Exp Biol Med (Maywood), 238, 1047-54.
    • (2013) Exp Biol Med (Maywood) , vol.238 , pp. 1047-1054
    • Ha, T.K.1    Kim, M.E.2    Yoon, J.H.3
  • 38
    • 84874004290 scopus 로고    scopus 로고
    • Amelioration of 1,2 Dimethylhydrazine (DMH) induced colon oxidative stress, inflammation and tumor promotion response by tannic acid in Wistar rats
    • Hamiza OO, Rehman MU, Tahir M, et al (2012). Amelioration of 1,2 Dimethylhydrazine (DMH) induced colon oxidative stress, inflammation and tumor promotion response by tannic acid in Wistar rats. Asian Pac J Cancer Prev, 13, 4393-402.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 4393-4402
    • Hamiza, O.O.1    Rehman, M.U.2    Tahir, M.3
  • 39
    • 0030602860 scopus 로고    scopus 로고
    • Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandinindependent pathway
    • Hanif R, Pittas A, Feng Y, et al (1996). Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandinindependent pathway. Biochem Pharmacol, 52, 237-45.
    • (1996) Biochem Pharmacol , vol.52 , pp. 237-245
    • Hanif, R.1    Pittas, A.2    Feng, Y.3
  • 40
    • 84877098153 scopus 로고    scopus 로고
    • Potential chemoprevention activity of Pterostilbene by enhancing the detoxifying enzymes in the HT-29 Cell Line
    • Harun Z, Ghazali AR (2012).Potential chemoprevention activity of Pterostilbene by enhancing the detoxifying enzymes in the HT-29 Cell Line. Asian Pac J Cancer Prev, 13, 6403-7.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 6403-6407
    • Harun, Z.1    Ghazali, A.R.2
  • 41
    • 0032483439 scopus 로고    scopus 로고
    • Identification of c-MYC as a target of the APC pathway
    • He TC, Sparks AB, Rago C, et al (1998). Identification of c-MYC as a target of the APC pathway. Science, 281, 1509-12.
    • (1998) Science , vol.281 , pp. 1509-1512
    • He, T.C.1    Sparks, A.B.2    Rago, C.3
  • 42
    • 0025835716 scopus 로고
    • Bcl2 protein is topographically restricted in tissues characterized by apoptotic cells death
    • Hockenbery DM, Zutter M, Hicky W, et al (1991). Bcl2 protein is topographically restricted in tissues characterized by apoptotic cells death. Proc Natl Acad Sci USA, 88, 6961-5.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 6961-6965
    • Hockenbery, D.M.1    Zutter, M.2    Hicky, W.3
  • 43
    • 84861831423 scopus 로고    scopus 로고
    • The role of Nrf2 and apoptotic signaling pathways in oroxylin A-mediated responses in HCT-116 colorectal adenocarcinoma cells and xenograft tumors
    • Hu R, Chen N, Yao J, et al (2012). The role of Nrf2 and apoptotic signaling pathways in oroxylin A-mediated responses in HCT-116 colorectal adenocarcinoma cells and xenograft tumors. Anticancer Drugs, 23, 651-8.
    • (2012) Anticancer Drugs , vol.23 , pp. 651-658
    • Hu, R.1    Chen, N.2    Yao, J.3
  • 44
    • 12344272682 scopus 로고    scopus 로고
    • Specific COX-2 inhibitor NS398 induces apoptosis in human liver cancer cell line HepG2 through BCL-2
    • Huang DS, Shen KZ, Wei JF, et al (2005). Specific COX-2 inhibitor NS398 induces apoptosis in human liver cancer cell line HepG2 through BCL-2. World J Gastroenterol, 11, 204-7.
    • (2005) World J Gastroenterol , vol.11 , pp. 204-207
    • Huang, D.S.1    Shen, K.Z.2    Wei, J.F.3
  • 45
    • 0037363922 scopus 로고    scopus 로고
    • HES and HERP families: multiple effectors of the Notch signaling pathway
    • Iso T, Kedes L, Hamamori Y (2003). HES and HERP families: multiple effectors of the Notch signaling pathway. J Cell Physiol, 194, 237-55. Kam PCA, See AUL (2000). Cyclo-oxygenaseisoenzymes: physiological and pharmacological role. Anaesthesia, 55, 442-9.
    • (2003) J Cell Physiol , vol.194 , pp. 237-255
    • Iso, T.1    Kedes, L.2    Hamamori, Y.3
  • 46
    • 0034062380 scopus 로고    scopus 로고
    • Cyclo-oxygenaseisoenzymes: physiological and pharmacological role
    • Kam PCA, See AUL (2000). Cyclo-oxygenaseisoenzymes: physiological and pharmacological role. Anaesthesia, 55, 442-9. Kang YJ, Park HJ, Chung HJ, et al (2012). Wnt/β-catenin signaling mediates the antitumor activity of magnolol in colorectal cancer cells. Mol Pharmacol, 82,168-77.
    • (2000) Anaesthesia , vol.55 , pp. 442-449
    • Kam, P.C.A.1    See, A.U.L.2
  • 47
    • 84863968745 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling mediates the antitumor activity of magnolol in colorectal cancer cells
    • Kang YJ, Park HJ, Chung HJ, et al (2012). Wnt/β-catenin signaling mediates the antitumor activity of magnolol in colorectal cancer cells. Mol Pharmacol, 82,168-77.
    • (2012) Mol Pharmacol , vol.82 , pp. 168-177
    • Kang, Y.J.1    Park, H.J.2    Chung, H.J.3
  • 48
    • 34748828940 scopus 로고    scopus 로고
    • Notch signaling in gastrointestinal tract (review)
    • Katoh M, Katoh M (2007). Notch signaling in gastrointestinal tract (review). Int J Oncol, 30, 247-51.
    • (2007) Int J Oncol , vol.30 , pp. 247-251
    • Katoh, M.1    Katoh, M.2
  • 49
    • 84864992319 scopus 로고    scopus 로고
    • Silibinin, a natural flavonoid, modulates the early expression of chemoprevention biomarkers in a preclinical model of colon carcinogenesis
    • Kauntz H, Bousserouel S, Gosse F, et al (2012). Silibinin, a natural flavonoid, modulates the early expression of chemoprevention biomarkers in a preclinical model of colon carcinogenesis. Int J Oncol, 41, 849-54.
    • (2012) Int J Oncol , vol.41 , pp. 849-854
    • Kauntz, H.1    Bousserouel, S.2    Gosse, F.3
  • 50
    • 84874007222 scopus 로고    scopus 로고
    • Glycyrrhizic acid suppresses the development of precancerous lesions via regulating the hyperproliferation, inflammation, angiogenesis and apoptosis inthe colon of Wistar rats
    • Khan R, Khan AQ, Lateef A, et al (2013). Glycyrrhizic acid suppresses the development of precancerous lesions via regulating the hyperproliferation, inflammation, angiogenesis and apoptosis inthe colon of Wistar rats. PLoS One, 8, 56020.
    • (2013) PLoS One , vol.8 , pp. 56020
    • Khan, R.1    Khan, A.Q.2    Lateef, A.3
  • 51
    • 84882658193 scopus 로고    scopus 로고
    • A ginseng metabolite, compound K, induces autophagy and apoptosis viageneration of reactive oxygen species and activation of JNK in human colon cancer cells
    • Kim AD, Kang KA, Kim HS, et al (2013). A ginseng metabolite, compound K, induces autophagy and apoptosis viageneration of reactive oxygen species and activation of JNK in human colon cancer cells. Cell Death Dis, 4, 750.
    • (2013) Cell Death Dis , vol.4 , pp. 750
    • Kim, A.D.1    Kang, K.A.2    Kim, H.S.3
  • 52
    • 84865114863 scopus 로고    scopus 로고
    • Quercetin enhances hypoxia-mediated apoptosis via direct inhibition of AMPK activity in HCT116 colon cancer
    • Kim HS, Wannatung T, Lee S, et al (2012). Quercetin enhances hypoxia-mediated apoptosis via direct inhibition of AMPK activity in HCT116 colon cancer. Apoptosis, 17, 938-49.
    • (2012) Apoptosis , vol.17 , pp. 938-949
    • Kim, H.S.1    Wannatung, T.2    Lee, S.3
  • 53
    • 84862572551 scopus 로고    scopus 로고
    • Dietary rice bran component γ-oryzanol inhibits tumor growth in tumorbearing mice
    • Kim SP, Kang MY, Nam SH, et al (2012a). Dietary rice bran component γ-oryzanol inhibits tumor growth in tumorbearing mice. Mol Nutr Food Res, 56, 935-44.
    • (2012) Mol Nutr Food Res , vol.56 , pp. 935-944
    • Kim, S.P.1    Kang, M.Y.2    Nam, S.H.3
  • 54
    • 14044254798 scopus 로고    scopus 로고
    • Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation
    • Kobayashi M, Yamamoto M (2005). Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation. Antioxid Redox Signal, 7, 385-94.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 385-394
    • Kobayashi, M.1    Yamamoto, M.2
  • 55
    • 73949113574 scopus 로고    scopus 로고
    • Notch-1 inhibition by Withaferin-A: a therapeutic target against colon carcinogenesis
    • Koduru S, Kumar R, Srinivasan S, et al (2010). Notch-1 inhibition by Withaferin-A: a therapeutic target against colon carcinogenesis. Mol Cancer Ther, 9, 202-10.
    • (2010) Mol Cancer Ther , vol.9 , pp. 202-210
    • Koduru, S.1    Kumar, R.2    Srinivasan, S.3
  • 56
    • 0030975671 scopus 로고    scopus 로고
    • Constitutive transcriptional activation by a β-catenin-Tcf complex in APC -/- colon carcinoma
    • Korinek V, Barker N, Morin PJ, et al (1997). Constitutive transcriptional activation by a β-catenin-Tcf complex in APC -/- colon carcinoma. Science, 275, 1784-7.
    • (1997) Science , vol.275 , pp. 1784-1787
    • Korinek, V.1    Barker, N.2    Morin, P.J.3
  • 57
    • 22544432640 scopus 로고    scopus 로고
    • Classification of cell death: recommendations of the Nomenclature Committee on Cell Death
    • Kroemer G, El-Deiry WS, Golstein P, et al (2005). Classification of cell death: recommendations of the Nomenclature Committee on Cell Death. Cell Death Differ, 12, 1463-67.
    • (2005) Cell Death Differ , vol.12 , pp. 1463-1467
    • Kroemer, G.1    El-Deiry, W.S.2    Golstein, P.3
  • 58
    • 84863135228 scopus 로고    scopus 로고
    • Preventive effects of curcumin on the development of azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db obese mice
    • Kubota M, Shimizu M, Sakai H, et al (2012).Preventive effects of curcumin on the development of azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db obese mice. Nutr Cancer, 64, 72-9.
    • (2012) Nutr Cancer , vol.64 , pp. 72-79
    • Kubota, M.1    Shimizu, M.2    Sakai, H.3
  • 59
    • 84865593352 scopus 로고    scopus 로고
    • Chemo preventive sphingadienes down regulate wnt signaling via a PP2A/Akt/GSK3β pathway in colon cancer
    • Kumar A, Pandurangan AK, Lu F, et al (2012). Chemo preventive sphingadienes down regulate wnt signaling via a PP2A/Akt/GSK3β pathway in colon cancer. Carcinogenesis, 33, 1726-35.
    • (2012) Carcinogenesis , vol.33 , pp. 1726-1735
    • Kumar, A.1    Pandurangan, A.K.2    Lu, F.3
  • 60
    • 0035296203 scopus 로고    scopus 로고
    • Role of nitric oxide in carcinogenesis and tumor progression
    • Lala PK, Chekraborty C (2001). Role of nitric oxide in carcinogenesis and tumor progression. Lancet Oncol, 3, 149-52.
    • (2001) Lancet Oncol , vol.3 , pp. 149-152
    • Lala, P.K.1    Chekraborty, C.2
  • 61
    • 19444379739 scopus 로고    scopus 로고
    • Nrf2 as a novel molecular target for chemoprevention
    • Lee JS, Surh YJ (2005). Nrf2 as a novel molecular target for chemoprevention. Cancer Lett, 224, 171-84.
    • (2005) Cancer Lett , vol.224 , pp. 171-184
    • Lee, J.S.1    Surh, Y.J.2
  • 62
    • 84880908541 scopus 로고    scopus 로고
    • Antitumor activity of 2-Hydroxycinnamaldehyde for human colon cancer cells through suppression of β-catenin signaling
    • Lee MA, Park HJ, Chung HJ, et al (2013). Antitumor activity of 2-Hydroxycinnamaldehyde for human colon cancer cells through suppression of β-catenin signaling. J Nat Prod, 76, 1278-84.
    • (2013) J Nat Prod , vol.76 , pp. 1278-1284
    • Lee, M.A.1    Park, H.J.2    Chung, H.J.3
  • 63
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P, Nijhawan D, Budihardjo I, et al (1997). Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell, 91, 479-89.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3
  • 64
    • 84879747271 scopus 로고    scopus 로고
    • Henryin, an entkauranediterpenoid, inhibits Wnt signaling through interference with β-catenin/TCF4 interaction in colorectal cancer cells
    • Li X, Pu J, Jiang S, et al (2013). Henryin, an entkauranediterpenoid, inhibits Wnt signaling through interference with β-catenin/TCF4 interaction in colorectal cancer cells. PLoS One, 8, 68525.
    • (2013) PLoS One , vol.8 , pp. 68525
    • Li, X.1    Pu, J.2    Jiang, S.3
  • 65
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c
    • Liu X, Kim CM, Yang J, et al (1996). Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell, 86, 147-57.
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.M.2    Yang, J.3
  • 66
    • 0027763413 scopus 로고
    • Cell division versus cell death: a functional model of multistep neoplasia
    • McDonnel TJ (1993). Cell division versus cell death: a functional model of multistep neoplasia. Mol Carcinogenesis, 8, 209-13.
    • (1993) Mol Carcinogenesis , vol.8 , pp. 209-213
    • McDonnel, T.J.1
  • 67
    • 0027397892 scopus 로고
    • Increased nitric oxide synthesis in ulcerative colitis
    • Middleton SJ, Shorthouse MJ, Hunter JO (1993). Increased nitric oxide synthesis in ulcerative colitis. Lancet, 341, 465.
    • (1993) Lancet , vol.341 , pp. 465
    • Middleton, S.J.1    Shorthouse, M.J.2    Hunter, J.O.3
  • 68
    • 84885109066 scopus 로고    scopus 로고
    • Suppression of colon carcinogenesis by targeting Notch signaling
    • Miyamoto S, Nakanishi M, Rosenberg DW (2013). Suppression of colon carcinogenesis by targeting Notch signaling. Carcinogenesis, 34, 2415-23.
    • (2013) Carcinogenesis , vol.34 , pp. 2415-2423
    • Miyamoto, S.1    Nakanishi, M.2    Rosenberg, D.W.3
  • 69
    • 0001003110 scopus 로고    scopus 로고
    • XTcf-3 transcription factor mediates β-catenin-induced axis formation in Xenopus embryos
    • Molenaar M, Wetering MVD, Oosterwegel M, et al (1996). XTcf-3 transcription factor mediates β-catenin-induced axis formation in Xenopus embryos. Cell, 86, 391-9.
    • (1996) Cell , vol.86 , pp. 391-399
    • Molenaar, M.1    Wetering, M.V.D.2    Oosterwegel, M.3
  • 70
    • 0030949463 scopus 로고    scopus 로고
    • Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    • Morin PJ, Sparks AB, Korinek V, et al (1997). Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science, 275, 1787-90.
    • (1997) Science , vol.275 , pp. 1787-1790
    • Morin, P.J.1    Sparks, A.B.2    Korinek, V.3
  • 71
    • 0030577102 scopus 로고    scopus 로고
    • The Albert Lasker Medical Research Awards. Signal transduction using nitric oxide and cyclic guanosine monophosphate
    • Murad F (1996). The Albert Lasker Medical Research Awards. Signal transduction using nitric oxide and cyclic guanosine monophosphate. JAMA, 276, 1189-92.
    • (1996) JAMA , vol.276 , pp. 1189-1192
    • Murad, F.1
  • 72
    • 84860856963 scopus 로고    scopus 로고
    • Chemopreventive efficacy of hesperetin (citrus flavonone) against 1,2-dimethylhydrazine-induced rat colon carcinogenesis
    • Nalini N, Aranganathan S, Kabalimurthy J (2012). Chemopreventive efficacy of hesperetin (citrus flavonone) against 1,2-dimethylhydrazine-induced rat colon carcinogenesis. Toxicol Mech Methods, 22, 397-408.
    • (2012) Toxicol Mech Methods , vol.22 , pp. 397-408
    • Nalini, N.1    Aranganathan, S.2    Kabalimurthy, J.3
  • 73
    • 0028019746 scopus 로고
    • Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria
    • Newmeyer DD, Farschon DM, Reed JC (1994). Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria. Cell, 79, 353-64.
    • (1994) Cell , vol.79 , pp. 353-364
    • Newmeyer, D.D.1    Farschon, D.M.2    Reed, J.C.3
  • 74
    • 77952890136 scopus 로고    scopus 로고
    • Anticarcinogenic efficacy of phytic acid extracted from rice bran on azoxymethane-induced colon carcinogenesis in rats
    • Norazalina S, Mohd.-Esa N, Hairuszah I, Norashareena MS (2010). Anticarcinogenic efficacy of phytic acid extracted from rice bran on azoxymethane-induced colon carcinogenesis in rats. Exp Toxicol Pathol, 62, 259-68.
    • (2010) Exp Toxicol Pathol , vol.62 , pp. 259-268
    • Norazalina, S.1    Mohd-Esa, N.2    Hairuszah, I.3    Norashareena, M.S.4
  • 75
    • 78650529785 scopus 로고    scopus 로고
    • Rice bran phytic acid (IP6) induces growth inhibition, cell cycle arrest and apoptosis on human colorectal adenocarcinoma cells
    • Nurul-Husna S, Norhaizan ME, Abdah MA, et al (2010). Rice bran phytic acid (IP6) induces growth inhibition, cell cycle arrest and apoptosis on human colorectal adenocarcinoma cells. J Med Plants Res, 4, 2283-9.
    • (2010) J Med Plants Res , vol.4 , pp. 2283-2289
    • Nurul-Husna, S.1    Norhaizan, M.E.2    Abdah, M.A.3
  • 76
    • 33748893228 scopus 로고    scopus 로고
    • Nrf2 regulates an adaptive response protecting against oxidative damage following diquat-mediated formation of superoxide anion
    • Osburn W, Wakabayashi N, Misra V, et al (2006). Nrf2 regulates an adaptive response protecting against oxidative damage following diquat-mediated formation of superoxide anion. Arch Biochem Biophys, 454, 7-15.
    • (2006) Arch Biochem Biophys , vol.454 , pp. 7-15
    • Osburn, W.1    Wakabayashi, N.2    Misra, V.3
  • 77
    • 84869995154 scopus 로고    scopus 로고
    • Antiinflammatory effects of resveratrol occur via inhibition of lipopolysaccharide-induced NF-κB activation in Caco-2 and SW480 human coloncancer cells
    • Panaro MA, Carofiglio V, Acquafredda A, et al (2012). Antiinflammatory effects of resveratrol occur via inhibition of lipopolysaccharide-induced NF-κB activation in Caco-2 and SW480 human coloncancer cells. Br J Nutr, 108, 1623-32.
    • (2012) Br J Nutr , vol.108 , pp. 1623-1632
    • Panaro, M.A.1    Carofiglio, V.2    Acquafredda, A.3
  • 78
    • 84880255103 scopus 로고    scopus 로고
    • Potential targets for the prevention of colorectal cancer: A focus on PI3K/Akt/mTOR and Wnt pathways
    • Pandurangan AK (2013). Potential targets for the prevention of colorectal cancer: A focus on PI3K/Akt/mTOR and Wnt pathways. Asian Pac J Cancer Prev, 14, 2201-5.
    • (2013) Asian Pac J Cancer Prev , vol.14 , pp. 2201-2205
    • Pandurangan, A.K.1
  • 81
    • 84884137005 scopus 로고    scopus 로고
    • Luteolin induces growth arrest in colon cancer cells through involvement of Wnt/β-catenin/GSK-3β signaling
    • Pandurangan AK, Dharmalingam P, AnandaSadagopan SK, et al (2013c). Luteolin induces growth arrest in colon cancer cells through involvement of Wnt/β-catenin/GSK-3β signaling. J Environ Pathol Toxicol Oncol, 32, 131-9.
    • (2013) J Environ Pathol Toxicol Oncol , vol.32 , pp. 131-139
    • Pandurangan, A.K.1    Dharmalingam, P.2    AnandaSadagopan, S.K.3
  • 82
    • 84880286722 scopus 로고    scopus 로고
    • Luteolin modulates cellular thiols on Azoxymenthane-induced colon carcinogenesis
    • Pandurangan AK, Ganapasam S (2013). Luteolin modulates cellular thiols on Azoxymenthane-induced colon carcinogenesis. Asian J Exp Bio lSci, 4, 245-50.
    • (2013) Asian J Exp Bio lSci , vol.4 , pp. 245-250
    • Pandurangan, A.K.1    Ganapasam, S.2
  • 83
    • 84877899687 scopus 로고    scopus 로고
    • Luteolin induces apoptosis in azoxymethane-induced colon carcinogenesis through involvement of Bcl-2, Bax, and Caspase-3
    • Pandurangan AK, Ganapsam S (2013). Luteolin induces apoptosis in azoxymethane-induced colon carcinogenesis through involvement of Bcl-2, Bax, and Caspase-3. J Chem Pharm Res, 5, 143-8.
    • (2013) J Chem Pharm Res , vol.5 , pp. 143-148
    • Pandurangan, A.K.1    Ganapsam, S.2
  • 84
    • 84880634420 scopus 로고    scopus 로고
    • Inhibitory effect of Luteolin on the status of membrane bound ATPases against Azoxymethane-induced colorectal cancer
    • Pandurangan AK, Dharmalingam P, Anandasadagopan SK, et al (2013). Inhibitory effect of Luteolin on the status of membrane bound ATPases against Azoxymethane-induced colorectal cancer. J Chem Pharm Res, 5, 123-7.
    • (2013) J Chem Pharm Res , vol.5 , pp. 123-127
    • Pandurangan, A.K.1    Dharmalingam, P.2    Anandasadagopan, S.K.3
  • 85
    • 84873027164 scopus 로고    scopus 로고
    • Effect of Luteolin on the levels of Glycoproteins during Azoxymethane-induced colon carcinogenesis in mice
    • Pandurangan AK, Dharmalingam P, Anandasadagopan SK, Ganapasam S (2012). Effect of Luteolin on the levels of Glycoproteins during Azoxymethane-induced colon carcinogenesis in mice. Asian Pac J Cancer Prev, 13, 1569-73.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 1569-1573
    • Pandurangan, A.K.1    Dharmalingam, P.2    Anandasadagopan, S.K.3    Ganapasam, S.4
  • 86
    • 84878869508 scopus 로고    scopus 로고
    • Cardamonin suppresses the proliferation of colon cancer cells by promoting β-catenin degradation
    • Park S, Gwak J, Han SJ, Oh S (2013).Cardamonin suppresses the proliferation of colon cancer cells by promoting β-catenin degradation. Biol Pharm Bull, 36, 1040-4.
    • (2013) Biol Pharm Bull , vol.36 , pp. 1040-1044
    • Park, S.1    Gwak, J.2    Han, S.J.3    Oh, S.4
  • 87
    • 38749114296 scopus 로고    scopus 로고
    • Polymeric black tea polyphenols inhibit 1, 2-dimethylhydrazine induced carcinogenesis by inhibiting cell proliferation via Wnt/β- catenin pathway
    • Patel R, Ingle A, Maru GB (2008). Polymeric black tea polyphenols inhibit 1, 2-dimethylhydrazine induced carcinogenesis by inhibiting cell proliferation via Wnt/β- catenin pathway. Toxicol Appl Pharmacol, 227, 136-46.
    • (2008) Toxicol Appl Pharmacol , vol.227 , pp. 136-146
    • Patel, R.1    Ingle, A.2    Maru, G.B.3
  • 88
    • 0031557898 scopus 로고    scopus 로고
    • The adenomatous polyposis coli (APC) tumor suppressor
    • Polakis P (1997). The adenomatous polyposis coli (APC) tumor suppressor. Biochim Biophys Acta, 1332, 127-47.
    • (1997) Biochim Biophys Acta , vol.1332 , pp. 127-147
    • Polakis, P.1
  • 89
    • 0026630266 scopus 로고
    • APC mutations occur early during colorectal tumorigenesis
    • Powell S, Zilz N, Beazer-Barclay Y, et al (1992). APC mutations occur early during colorectal tumorigenesis. Nature, 359, 235-7.
    • (1992) Nature , vol.359 , pp. 235-237
    • Powell, S.1    Zilz, N.2    Beazer-Barclay, Y.3
  • 90
    • 62849123061 scopus 로고    scopus 로고
    • Antioxidative and antiproliferative effects of astaxanthin during the initiation stages of 1,2-dimethyl hydrazine-inducedexperimental colon carcinogenesis
    • Prabhu PN, Ashokkumar P, Sudhandiran G (2009). Antioxidative and antiproliferative effects of astaxanthin during the initiation stages of 1,2-dimethyl hydrazine-inducedexperimental colon carcinogenesis. Fundam Clin Pharmacol, 23, 225-34.
    • (2009) Fundam Clin Pharmacol , vol.23 , pp. 225-234
    • Prabhu, P.N.1    Ashokkumar, P.2    Sudhandiran, G.3
  • 91
    • 84881643495 scopus 로고    scopus 로고
    • Yerba mate tea and mate saponins prevented azoxymethane-induced inflammation of rat colon through suppression of NF-κB p65ser(311) signaling via IκB-α and GSK-3β reduced phosphorylation
    • Puangpraphant S, Dia VP, de Mejia EG, et al (2013). Yerba mate tea and mate saponins prevented azoxymethane-induced inflammation of rat colon through suppression of NF-κB p65ser(311) signaling via IκB-α and GSK-3β reduced phosphorylation. Biofactors, 39, 430-40.
    • (2013) Biofactors , vol.39 , pp. 430-440
    • Puangpraphant, S.1    Dia, V.P.2    de Mejia, E.G.3
  • 92
    • 0007755935 scopus 로고    scopus 로고
    • Chemoprevention of colon cancer by iNOS specific and non-specific inhibitors: a safer colon cancer chemopreventive strategy
    • Rao CV, Kawamori T, Hamid R, et al (1998). Chemoprevention of colon cancer by iNOS specific and non-specific inhibitors: a safer colon cancer chemopreventive strategy. Proc Am Assoc Cancer Res, 39, 197.
    • (1998) Proc Am Assoc Cancer Res , vol.39 , pp. 197
    • Rao, C.V.1    Kawamori, T.2    Hamid, R.3
  • 94
    • 3242804439 scopus 로고    scopus 로고
    • Studies with the azoxymethane-rat preclinical model for assessing colon tumor development and chemoprevention
    • Reddy BS(2004). Studies with the azoxymethane-rat preclinical model for assessing colon tumor development and chemoprevention. Environ Mol Mutagen, 44, 26-35.
    • (2004) Environ Mol Mutagen , vol.44 , pp. 26-35
    • Reddy, B.S.1
  • 95
    • 0034650771 scopus 로고    scopus 로고
    • Chemoprevention of colon cancer by specific cycloxygenase-2 inhibitor, celeoxib, administrated during different stages of carcinogenesis
    • Reddy BS, Hirose Y, Lubet R, et al (2000). Chemoprevention of colon cancer by specific cycloxygenase-2 inhibitor, celeoxib, administrated during different stages of carcinogenesis. Cancer Res, 60, 293-298.
    • (2000) Cancer Res , vol.60 , pp. 293-298
    • Reddy, B.S.1    Hirose, Y.2    Lubet, R.3
  • 96
    • 59049088446 scopus 로고    scopus 로고
    • Activation of Notch signaling in human colon adenocarcinoma
    • Reedijk M, Odorcic S, Zhang H, et al (2008). Activation of Notch signaling in human colon adenocarcinoma. Int J Oncol, 33, 1223-9.
    • (2008) Int J Oncol , vol.33 , pp. 1223-1229
    • Reedijk, M.1    Odorcic, S.2    Zhang, H.3
  • 97
    • 84880346496 scopus 로고    scopus 로고
    • Suppression of β-catenin and cyclooxygenase-2 on expression and cell proliferation in azoxymethane-induced colonic cancer in rats by rice bran phytic acid (PA)
    • Saad N, Esa NM, Ithnin H (2013). Suppression of β-catenin and cyclooxygenase-2 on expression and cell proliferation in azoxymethane-induced colonic cancer in rats by rice bran phytic acid (PA). Asian Pac J Cancer Prev, 14, 3093-9.
    • (2013) Asian Pac J Cancer Prev , vol.14 , pp. 3093-3099
    • Saad, N.1    Esa, N.M.2    Ithnin, H.3
  • 99
    • 84883466738 scopus 로고    scopus 로고
    • Chemopreventive activity of plant flavonoid isorhamnetin in colorectal cancer is mediated by oncogenic Src and β-Catenin
    • Saud SM, Young MR, Jones-Hall YL, et al (2013). Chemopreventive activity of plant flavonoid isorhamnetin in colorectal cancer is mediated by oncogenic Src and β-Catenin. Cancer Res, 73, 5473-84.
    • (2013) Cancer Res , vol.73 , pp. 5473-5484
    • Saud, S.M.1    Young, M.R.2    Jones-Hall, Y.L.3
  • 100
  • 101
    • 85008398010 scopus 로고    scopus 로고
    • Prophylactic Inositol Hexaphosphate (IP6) inhibits colon cancer through involvement of Wnt/β-catenin and COX-2 pathway
    • Shafie NH, MohdEsa NM, Ithnin H, et al (2013). Prophylactic Inositol Hexaphosphate (IP6) inhibits colon cancer through involvement of Wnt/β-catenin and COX-2 pathway. BioMed Res Int, 2013, 10.
    • (2013) BioMed Res Int , vol.2013 , pp. 10
    • Shafie, N.H.1    MohdEsa, N.M.2    Ithnin, H.3
  • 102
    • 0031984810 scopus 로고    scopus 로고
    • Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells
    • Sheng H, Shao J, Morrow JD, et al (1998). Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. Cancer Res, 58, 362-6.
    • (1998) Cancer Res , vol.58 , pp. 362-366
    • Sheng, H.1    Shao, J.2    Morrow, J.D.3
  • 103
    • 0029829236 scopus 로고    scopus 로고
    • Identification and characterization of a gene encoding a gut-enriched Krüppellike factor expressed during growth arrest
    • Shields JM, Christy RJ, Yang VW (1996). Identification and characterization of a gene encoding a gut-enriched Krüppellike factor expressed during growth arrest. J Biol Chem, 271, 20009-17.
    • (1996) J Biol Chem , vol.271 , pp. 20009-20017
    • Shields, J.M.1    Christy, R.J.2    Yang, V.W.3
  • 104
    • 0025280477 scopus 로고
    • Primary prevention of colorectal cancer: WHO collaborating center for prevention of colorectal cancer
    • Shike M, Winawar SJ, Greenwald PH, et al (1990). Primary prevention of colorectal cancer: WHO collaborating center for prevention of colorectal cancer. Bull WHO, 68, 377-85.
    • (1990) Bull WHO , vol.68 , pp. 377-385
    • Shike, M.1    Winawar, S.J.2    Greenwald, P.H.3
  • 105
    • 76749112922 scopus 로고    scopus 로고
    • NOTCH signaling is required for formation and selfrenewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer
    • Sikandar SS, Pate KT, Anderson S, et al (2010). NOTCH signaling is required for formation and selfrenewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer. Cancer Res, 70, 1469-78.
    • (2010) Cancer Res , vol.70 , pp. 1469-1478
    • Sikandar, S.S.1    Pate, K.T.2    Anderson, S.3
  • 106
    • 80555123045 scopus 로고    scopus 로고
    • Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications
    • Singh BN, Shankar S, Srivastava RK (2011). Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications. Biochem Pharmacol, 82, 1807-21.
    • (2011) Biochem Pharmacol , vol.82 , pp. 1807-1821
    • Singh, B.N.1    Shankar, S.2    Srivastava, R.K.3
  • 107
    • 0033569986 scopus 로고    scopus 로고
    • Life style and colon cancer: an assessment of factors associated with risk
    • Slattery ML, Edwards SL, Boucher KM, et al (1999). Life style and colon cancer: an assessment of factors associated with risk. Am J Epidemiol, 150, 869-77.
    • (1999) Am J Epidemiol , vol.150 , pp. 869-877
    • Slattery, M.L.1    Edwards, S.L.2    Boucher, K.M.3
  • 108
    • 0026082126 scopus 로고
    • Metabolism of azoxymethane, methylazoxymethanol and N-nitrosodimethylamine by cytochrome P450IIE1
    • Sohn OS, Ishizaki H, Yang CS, Fiala ES (1991). Metabolism of azoxymethane, methylazoxymethanol and N-nitrosodimethylamine by cytochrome P450IIE1. Carcinogenesis, 12, 127-31.
    • (1991) Carcinogenesis , vol.12 , pp. 127-131
    • Sohn, O.S.1    Ishizaki, H.2    Yang, C.S.3    Fiala, E.S.4
  • 109
    • 0032521433 scopus 로고    scopus 로고
    • Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer
    • Sparks AB, Morin PJ, Vogelstein B, Kinzler KW (1998). Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer. Cancer Res, 58, 1130-4.
    • (1998) Cancer Res , vol.58 , pp. 1130-1134
    • Sparks, A.B.1    Morin, P.J.2    Vogelstein, B.3    Kinzler, K.W.4
  • 110
    • 84873896815 scopus 로고    scopus 로고
    • Effects of hexahydrocurcumin in combination with 5-fluorouracil on dimethylhydrazine-induced colon cancer in rats
    • Srimuangwong K, Tocharus C, Tocharus J, et al (2012). Effects of hexahydrocurcumin in combination with 5-fluorouracil on dimethylhydrazine-induced colon cancer in rats. World J Gastroenterol, 18, 6951-9.
    • (2012) World J Gastroenterol , vol.18 , pp. 6951-6959
    • Srimuangwong, K.1    Tocharus, C.2    Tocharus, J.3
  • 111
    • 0032085941 scopus 로고    scopus 로고
    • Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
    • Srinivasula SM, Ahmad M, Fernandes-Alnemri T, et al (1998). Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization. Mol Cell, 1, 949-57.
    • (1998) Mol Cell , vol.1 , pp. 949-957
    • Srinivasula, S.M.1    Ahmad, M.2    Fernandes-Alnemri, T.3
  • 112
    • 41349115251 scopus 로고    scopus 로고
    • Diallyl sulfide induces apoptosis in Colo 320 DM human colon cancer cells: involvement of caspase-3, NF-κB, and ERK-2
    • Sriram N, Kalayarasan S, Ashokkumar P, et al (2008). Diallyl sulfide induces apoptosis in Colo 320 DM human colon cancer cells: involvement of caspase-3, NF-κB, and ERK-2. Mol Cell Biochem, 311, 157-65.
    • (2008) Mol Cell Biochem , vol.311 , pp. 157-165
    • Sriram, N.1    Kalayarasan, S.2    Ashokkumar, P.3
  • 113
    • 0029783253 scopus 로고    scopus 로고
    • Transcription of cyclooxygenase-2 is enhanced in transformed mammary epithelial cells
    • Subbaramiah K, Telang N, Ramonetti JT, et al (1996). Transcription of cyclooxygenase-2 is enhanced in transformed mammary epithelial cells. Cancer Res, 56, 4424-9.
    • (1996) Cancer Res , vol.56 , pp. 4424-4429
    • Subbaramiah, K.1    Telang, N.2    Ramonetti, J.T.3
  • 114
    • 0032958592 scopus 로고    scopus 로고
    • Frequent mutations of the rat β-catenin gene in colon cancers induced by methylazoxymethanol acetate plus 1-hydroxyanthraquinone
    • Suzui M, Ushijima T, Dashwood RH, et al (1999). Frequent mutations of the rat β-catenin gene in colon cancers induced by methylazoxymethanol acetate plus 1-hydroxyanthraquinone. Mol Carcinogenesis, 24, 232-7.
    • (1999) Mol Carcinogenesis , vol.24 , pp. 232-237
    • Suzui, M.1    Ushijima, T.2    Dashwood, R.H.3
  • 115
    • 0030901206 scopus 로고    scopus 로고
    • Increased expression of inducible and endothelial constitutive nitric oxide synthases in rat colon tumors induced by azoxymethane
    • Takahashi M, Fukuda K, Ohata T, et al (1997). Increased expression of inducible and endothelial constitutive nitric oxide synthases in rat colon tumors induced by azoxymethane. Cancer Res, 57, 1233-7.
    • (1997) Cancer Res , vol.57 , pp. 1233-1237
    • Takahashi, M.1    Fukuda, K.2    Ohata, T.3
  • 116
    • 0031984227 scopus 로고    scopus 로고
    • β-Catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors
    • Takahashi M, Fukuda K, Sugimura T, et al (1998). β-Catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors. Cancer Res, 58, 42-6.
    • (1998) Cancer Res , vol.58 , pp. 42-46
    • Takahashi, M.1    Fukuda, K.2    Sugimura, T.3
  • 118
    • 77956627421 scopus 로고    scopus 로고
    • Chemoprevention of 1,2-Dimethylhydrazine-induced colon carcinogenesis by a Non-steroidal anti-inflammatory drug, etoricoxib, in rats: Inhibition of nuclear factor κB
    • Tanwar L, Vaish V, Sanyal SN (2009). Chemoprevention of 1,2-Dimethylhydrazine-induced colon carcinogenesis by a Non-steroidal anti-inflammatory drug, etoricoxib, in rats: Inhibition of nuclear factor κB. Asian Pac J Cancer Prev, 10, 1141-6.
    • (2009) Asian Pac J Cancer Prev , vol.10 , pp. 1141-1146
    • Tanwar, L.1    Vaish, V.2    Sanyal, S.N.3
  • 119
    • 0033119801 scopus 로고    scopus 로고
    • β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O, McCormick F (1999). β-Catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature, 398, 422-6.
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 120
    • 0025998557 scopus 로고
    • Aspirin use and reduced risk of fatal colon cancer
    • Thun MJ, Namboodiri MM, Heath Jr CW (1991). Aspirin use and reduced risk of fatal colon cancer. N Engl J Med, 325, 1593-6.
    • (1991) N Engl J Med , vol.325 , pp. 1593-1596
    • Thun, M.J.1    Namboodiri, M.M.2    Heath Jr., C.W.3
  • 121
    • 0028803728 scopus 로고
    • Alteration in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
    • Tsujii M, DuBois RN (1995). Alteration in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell, 83, 493-501.
    • (1995) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    DuBois, R.N.2
  • 122
    • 0036177671 scopus 로고    scopus 로고
    • Cyclooxygenase-2: a therapeutic target
    • Turini ME, DuBois RN (2002). Cyclooxygenase-2: a therapeutic target. Annu Rev Med, 53, 35-57.
    • (2002) Annu Rev Med , vol.53 , pp. 35-57
    • Turini, M.E.1    DuBois, R.N.2
  • 123
    • 20544460148 scopus 로고    scopus 로고
    • Notch/gammasecretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
    • van Es JH, van Gijn ME, Riccio O, et al (2005). Notch/gammasecretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature, 435, 959-63.
    • (2005) Nature , vol.435 , pp. 959-963
    • van Es, J.H.1    van Gijn, M.E.2    Riccio, O.3
  • 124
    • 84878493132 scopus 로고    scopus 로고
    • Ursolic acid simultaneously targets multiple signaling pathways to suppress proliferation and induce apoptosis in colon cancer cells
    • Wang J, Liu L, Qiu H, et al (2013). Ursolic acid simultaneously targets multiple signaling pathways to suppress proliferation and induce apoptosis in colon cancer cells. PLoS One, 8, 63872.
    • (2013) PLoS One , vol.8 , pp. 63872
    • Wang, J.1    Liu, L.2    Qiu, H.3
  • 125
    • 84870721115 scopus 로고    scopus 로고
    • Gelam and Nenas honeys inhibit proliferation of HT 29 colon cancer cells by inducing DNA damage and apoptosis while suppressing inflammation
    • Wen CTP, Hussein SZ, Abdullah S, et al (2012). Gelam and Nenas honeys inhibit proliferation of HT 29 colon cancer cells by inducing DNA damage and apoptosis while suppressing inflammation. Asian Pac J Cancer Prev, 13, 6403-7.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 6403-6407
    • Wen, C.T.P.1    Hussein, S.Z.2    Abdullah, S.3
  • 127
    • 0033590207 scopus 로고    scopus 로고
    • The role of cyclooxygenases in inflammation, cancer, and development
    • Williams CS, Mann M, DuBois RN (1999). The role of cyclooxygenases in inflammation, cancer, and development. Oncogene, 18, 7908-16.
    • (1999) Oncogene , vol.18 , pp. 7908-7916
    • Williams, C.S.1    Mann, M.2    DuBois, R.N.3
  • 128
    • 0032406715 scopus 로고    scopus 로고
    • Mechanisms of Wnt signaling indevelopment
    • Wodarz A, Nusse R (1998). Mechanisms of Wnt signaling indevelopment. Annu Rev Cell DevBiol, 14, 59-88.
    • (1998) Annu Rev Cell DevBiol , vol.14 , pp. 59-88
    • Wodarz, A.1    Nusse, R.2
  • 129
    • 77952827500 scopus 로고    scopus 로고
    • The cinnamon-derived dietary factor cinnamic aldehyde activates the Nrf2-dependent antioxidant response in human epithelial colon cells
    • Wondrak GT, Villeneuve NF, Lamore SD, et al (2010).The cinnamon-derived dietary factor cinnamic aldehyde activates the Nrf2-dependent antioxidant response in human epithelial colon cells. Molecules, 15, 3338-55.
    • (2010) Molecules , vol.15 , pp. 3338-3355
    • Wondrak, G.T.1    Villeneuve, N.F.2    Lamore, S.D.3
  • 130
    • 84862315403 scopus 로고    scopus 로고
    • γ-Tocotrienol inhibits cell viability through suppression of β-catenin/Tcf signaling in human colon carcinoma HT-29 cells
    • Xu W, Du M, Zhao Y, et al (2012). γ-Tocotrienol inhibits cell viability through suppression of β-catenin/Tcf signaling in human colon carcinoma HT-29 cells. J Nutr Biochem, 23, 800-7.
    • (2012) J Nutr Biochem , vol.23 , pp. 800-807
    • Xu, W.1    Du, M.2    Zhao, Y.3
  • 131
    • 0030277219 scopus 로고    scopus 로고
    • Higher expression of oncoproteins c-myc, c-erbB-2/neu, PCNA and p53 in metastasizing colorectal cancer than in nonmetastasizing tumors
    • Yang JL, Ow KT, Russell PJ, et al (1996). Higher expression of oncoproteins c-myc, c-erbB-2/neu, PCNA and p53 in metastasizing colorectal cancer than in nonmetastasizing tumors. Ann Surg Oncol, 3, 574-9.
    • (1996) Ann Surg Oncol , vol.3 , pp. 574-579
    • Yang, J.L.1    Ow, K.T.2    Russell, P.J.3
  • 132
    • 85008412798 scopus 로고    scopus 로고
    • The protective effect of cocoa (Theobroma cacao L.) in colon cancer
    • Yazan R, Faisal A, Norhaizan ME (2013). The protective effect of cocoa (Theobroma cacao L.) in colon cancer. J Nutr Food Sci, 3, 1-3.
    • (2013) J Nutr Food Sci , vol.3 , pp. 1-3
    • Yazan, R.1    Faisal, A.2    Norhaizan, M.E.3
  • 133
    • 0037462796 scopus 로고    scopus 로고
    • Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage
    • Yoon HS, Chen X, Yang VW (2003). Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage. J Biol Chem, 278, 2101-5.
    • (2003) J Biol Chem , vol.278 , pp. 2101-2105
    • Yoon, H.S.1    Chen, X.2    Yang, V.W.3
  • 134
    • 35048858890 scopus 로고    scopus 로고
    • Inhibition of epigallocatechingallate on orthotopic colon cancer by upregulating the Nrf2-UGT1A signal pathway in nude mice
    • Yuan JH, Li YQ, Yang XY (2007). Inhibition of epigallocatechingallate on orthotopic colon cancer by upregulating the Nrf2-UGT1A signal pathway in nude mice. Pharmacol, 80, 269-78.
    • (2007) Pharmacol , vol.80 , pp. 269-278
    • Yuan, J.H.1    Li, Y.Q.2    Yang, X.Y.3
  • 135
    • 0029078323 scopus 로고
    • Alterations in Notch signaling in neoplastic lesions of the human cervix
    • Zagouras P, Stifani S, Blaumueller CM, et al (1995). Alterations in Notch signaling in neoplastic lesions of the human cervix. Proc Natl Acad Sci U S A, 92, 6414-8.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 6414-6418
    • Zagouras, P.1    Stifani, S.2    Blaumueller, C.M.3
  • 136
    • 84872030397 scopus 로고    scopus 로고
    • Genistein, a soya isoflavone, prevents azoxymethane-induced up-regulation of WNT/β-catenin signalling and reduces colon pre-neoplasia in rats
    • Zhang Y, Li Q, Zhou D, Chen H (2013). Genistein, a soya isoflavone, prevents azoxymethane-induced up-regulation of WNT/β-catenin signalling and reduces colon pre-neoplasia in rats. Br J Nutr, 109, 33-42.
    • (2013) Br J Nutr , vol.109 , pp. 33-42
    • Zhang, Y.1    Li, Q.2    Zhou, D.3    Chen, H.4
  • 137
    • 70349554099 scopus 로고    scopus 로고
    • Modulation of NRF2 and UGT1A expression by epigallocatechin-3-gallate in colon cancer cells and BALB/c mice
    • Zhang ZM, Yang XY, Yuan JH, et al (2009). Modulation of NRF2 and UGT1A expression by epigallocatechin-3-gallate in colon cancer cells and BALB/c mice. Chin Med J, 122, 1660-5.
    • (2009) Chin Med J , vol.122 , pp. 1660-1665
    • Zhang, Z.M.1    Yang, X.Y.2    Yuan, J.H.3
  • 138
    • 0842329848 scopus 로고    scopus 로고
    • Identification of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer
    • Zhao W, Hisamuddin IM, Nandan MO, et al (2004). Identification of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer. Oncogene, 23, 395-402.
    • (2004) Oncogene , vol.23 , pp. 395-402
    • Zhao, W.1    Hisamuddin, I.M.2    Nandan, M.O.3
  • 139
    • 20444381360 scopus 로고    scopus 로고
    • Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: Protection against reactive oxygen and nitrogen species-induced cell injury
    • Zhu H, Itoh K, Yaamamoto M, et al (2005). Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: Protection against reactive oxygen and nitrogen species-induced cell injury. FEBS Lett, 579, 3029-36.
    • (2005) FEBS Lett , vol.579 , pp. 3029-3036
    • Zhu, H.1    Itoh, K.2    Yaamamoto, M.3
  • 140
    • 84864308272 scopus 로고    scopus 로고
    • iNOS signaling interacts with COX-2 pathway in colonic fibroblasts
    • Zhu Y, Zhu M, Lance P (2012). iNOS signaling interacts with COX-2 pathway in colonic fibroblasts. Exp Cell Res, 318, 2116-27.
    • (2012) Exp Cell Res , vol.318 , pp. 2116-2127
    • Zhu, Y.1    Zhu, M.2    Lance, P.3
  • 141
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
    • Zou H, Henzel WJ, Liu XS, et al (1997). Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell, 90, 405-13.
    • (1997) Cell , vol.90 , pp. 405-413
    • Zou, H.1    Henzel, W.J.2    Liu, X.S.3


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