Henryin, an ent-kaurane Diterpenoid, Inhibits Wnt Signaling through Interference with β-Catenin/TCF4 Interaction in Colorectal Cancer Cells

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Li, Xingyao ^a,c   Pu, Jianxin ^a   Jiang, Shiyou ^b,c   Su, Jia ^a,c   Kong, Lingmei ^a,c   Mao, Bingyu ^b   Sun, Handong ^a   Li, Yan ^a  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b KUNMING INSTITUTE OF ZOOLOGY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CYCLIN D1; DITERPENOID; HENRYIN; MYC PROTEIN; TCF4 PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; WNT PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL STRAIN HCT116; COLORECTAL CANCER; COMPLEX FORMATION; CONTROLLED STUDY; CYTOSOL; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REPORTER GENE; S PHASE CELL CYCLE CHECKPOINT; STRUCTURE ACTIVITY RELATION; WNT SIGNALING PATHWAY;

BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BETA CATENIN; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DITERPENES, KAURANE; DOSE-RESPONSE RELATIONSHIP, DRUG; G1 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HT29 CELLS; HUMANS; MOLECULAR STRUCTURE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BINDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS; TRANSCRIPTION FACTORS; WNT SIGNALING PATHWAY;

RABDOSIA RUBESCENS;

EID: 84879747271     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0068525     Document Type: Article

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