A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells

Cell Death and Disease

Volumn 4, Issue 8, 2013, Pages

  Kim, A D ^a   Kang, K A ^a   Kim, H S ^b,f   Kim, D H ^c   Choi, Y H ^d   Lee, S J ^e   Hyun, J W ^a  

^a Jeju National University   (South Korea)

^b Ewha Womans University School of Medicine   (South Korea)

^c Kyung Hee University   (South Korea)

^d Dong Eui University   (South Korea)

^e Hanyang University   (South Korea)

^f Seoul National University College of Medicine   (South Korea)

Author keywords

Apoptosis; Autophagy; Colon cancer; Compound K; Reactive oxygen species

Indexed keywords

ACRIDINE ORANGE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; COMPOUND K; GINSENOSIDE; PROTEIN BCL 2; PROTEIN BCL X; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CANCER CELL CULTURE; CELL DEATH; CELL STRAIN HCT116; COLON CANCER; GINSENG; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; METABOLITE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 84882658193     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.273     Document Type: Article

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