The natural alkaloid berberine targets multiple pathways to induce cell death in cultured human colon cancer cells

European Journal of Pharmacology

Volumn 688, Issue 1-3, 2012, Pages 14-21

  Chidambara Murthy, Kotamballi N ^a   Jayaprakasha, Guddadarangavvanahally K ^a   Patil, Bhimanagouda S ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Anti inflammatory; Apoptosis; Berberine; Caspases; Colon cancer; SW480 cells

Indexed keywords

BERBERINE; CASPASE; CASPASE 8; CYCLOOXYGENASE 2; CYTOCHROME C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN P21; SURVIVIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; VASCULOTROPIN;

ANTIANGIOGENIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CELL PROLIFERATION; CHEMOPROPHYLAXIS; COLON ADENOCARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DRUG CYTOTOXICITY; DRUG TARGETING; ENZYME RELEASE; HUMAN; HUMAN CELL; INFLAMMATION; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN INDUCTION; TUMOR VASCULARIZATION;

BERBERINE; BIOLOGICAL AGENTS; CASPASE 8; CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; G0 PHASE; G1 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MITOCHONDRIAL MEMBRANES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84863529339     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.05.004     Document Type: Article

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