Quercetin enhances hypoxia-mediated apoptosis via direct inhibition of AMPK activity in HCT116 colon cancer

Apoptosis

Volumn 17, Issue 9, 2012, Pages 938-949

  Kim, Hak Su ^a   Wannatung, Tirawat ^a   Lee, Sooho ^a   Yang, Woo Kyeom ^a   Chung, Sung Hyun ^b   Lim, Jong Seok ^c   Choe, Wonchae ^a   Kang, Insug ^a   Kim, Sung Soo ^a   Ha, Joohun ^a  

^a Kyung Hee University Hospital   (South Korea)

^b Kyung Hee University   (South Korea)

^c Sookmyung Women's University   (South Korea)

Author keywords

AMPK; Apotosis; HIF 1 ; Hypoxia; Quercetin

Indexed keywords

ADENYLATE KINASE; CISPLATIN; ETOPOSIDE; HYPOXIA INDUCIBLE FACTOR 1; QUERCETIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL HYPOXIA; CELL STRAIN HCT116; COLON CANCER; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR XENOGRAFT;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; CELL HYPOXIA; CELL LINE, TUMOR; CISPLATIN; COLONIC NEOPLASMS; ETOPOSIDE; GENES, REPORTER; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM TRANSPLANTATION; QUERCETIN; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84865114863     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-012-0719-0     Document Type: Article

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