The role of Nrf2 and apoptotic signaling pathways in oroxylin A-mediated responses in HCT-116 colorectal adenocarcinoma cells and xenograft tumors

Anti-Cancer Drugs

Volumn 23, Issue 6, 2012, Pages 651-658

  Hu, Rong ^a   Chen, Nan ^a   Yao, Jing ^a   Zhao, Qing ^a   Zhang, Fengyi ^a   Li, Zhi Yu ^a   You, Qi Dong ^a   Guo, Qing Long ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

apoptosis; chemoprevention; Nrf2; oroxylin A

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; HEME OXYGENASE 1; LIPOCORTIN 5; OROXYLIN A; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TRANSCRIPTION FACTOR NRF2;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BODY WEIGHT; CELL STRAIN HCT116; COLORECTAL CARCINOMA; CONTROLLED STUDY; ENZYME ACTIVATION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RANDOMIZED CONTROLLED TRIAL; SIGNAL TRANSDUCTION; TUMOR VOLUME; TUMOR XENOGRAFT;

ADENOCARCINOMA; ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; CASPASE 9; CELL LINE, TUMOR; CELL NUCLEUS; COLORECTAL NEOPLASMS; FLAVONOIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HEME OXYGENASE-1; HUMANS; MALE; MICE; MICE, INBRED BALB C; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84861831423     PISSN: 09594973     EISSN: 14735741     Source Type: Journal    
DOI: 10.1097/CAD.0b013e3283512703     Document Type: Article

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