-
1
-
-
77950465577
-
Familial forms of nephrotic syndrome
-
Caridi G, Trivelli A, Sanna-Cherchi S, Perfumo F, Ghiggeri GM: Familial forms of nephrotic syndrome. Pediatr Nephrol 2010;25:241-252
-
(2010)
Pediatr Nephrol
, Issue.25
, pp. 241-252
-
-
Caridi, G.1
Trivelli, A.2
Sanna-Cherchi, S.3
Perfumo, F.4
Ghiggeri, G.M.5
-
3
-
-
0033038682
-
Subcellular localization of glucocorticoid receptor protein in the human kidney glomerulus
-
Yan K, Kudo A, Hirano H, Watanabe T, Tasaka T, Kataoka S, Nakajima N, Nishibori Y, Shibata T, Kohsaka T, Higashihara E, Tanaka H, Watanabe H, Nagasawa T, Awa S: Subcellular localization of glucocorticoid receptor protein in the human kidney glomerulus. Kidney Int 1999;56:65-73
-
(1999)
Kidney Int
, vol.56
, pp. 65-73
-
-
Yan, K.1
Kudo, A.2
Hirano, H.3
Watanabe, T.4
Tasaka, T.5
Kataoka, S.6
Nakajima, N.7
Nishibori, Y.8
Shibata, T.9
Kohsaka, T.10
Higashihara, E.11
Tanaka, H.12
Watanabe, H.13
Nagasawa, T.14
Awa, S.15
-
4
-
-
73249115366
-
Crosstalk in inflammation: The interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases
-
Beck IM, Vanden Berghe W, Vermeulen L, Yamamoto KR, Haegeman G, De Bosscher K: Crosstalk in inflammation: The interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases. Endocr Rev 2009;30:830-882
-
(2009)
Endocr Rev
, vol.30
, pp. 830-882
-
-
Beck, I.M.1
Vanden Berghe, W.2
Vermeulen, L.3
Yamamoto, K.R.4
Haegeman, G.5
De Bosscher, K.6
-
5
-
-
0025895395
-
The genomic structure of the human glucocorticoid receptor
-
Encio IJ, Detera-Wadleigh SD: The genomic structure of the human glucocorticoid receptor. J Biol Chem 1991;266:7182-7188
-
(1991)
J Biol Chem
, vol.266
, pp. 7182-7188
-
-
Encio, I.J.1
Detera-Wadleigh, S.D.2
-
6
-
-
0032160629
-
The DNA-binding and tau2 transactivation domains of the rat glucocorticoid receptor constitute a nuclear matrix-targeting signal
-
Tang Y, Getzenberg RH, Vietmeier BN, Stallcup MR, Eggert M, Renkawitz R, DeFranco DB: The DNA-binding and tau2 transactivation domains of the rat glucocorticoid receptor constitute a nuclear matrix-targeting signal. Mol Endocrinol 1998;12:1420-1431
-
(1998)
Mol Endocrinol
, vol.12
, pp. 1420-1431
-
-
Tang, Y.1
Getzenberg, R.H.2
Vietmeier, B.N.3
Stallcup, M.R.4
Eggert, M.5
Renkawitz, R.6
DeFranco, D.B.7
-
7
-
-
18144399332
-
The human glucocorticoid receptor: One gene, multiple proteins and diverse responses
-
Zhou J, Cidlowski J: The human glucocorticoid receptor: One gene, multiple proteins and diverse responses. Steroids 2005;70:407-417
-
(2005)
Steroids
, vol.70
, pp. 407-417
-
-
Zhou, J.1
Cidlowski, J.2
-
9
-
-
79953726304
-
Glucocorticosteroids: Current and future directions
-
PJ B
-
PJ B: Glucocorticosteroids: Current and future directions. Br J Pharmacol 2011;163:29-43
-
(2011)
Br J Pharmacol
, Issue.163
, pp. 29-43
-
-
-
10
-
-
0030925683
-
Steroid receptor interactions with heat shock protein and immunophilin chaperones
-
Pratt WB, Toft DO: Steroid receptor interactions with heat shock protein and immunophilin chaperones. Endocr Rev 1997;18:306-360
-
(1997)
Endocr Rev
, vol.18
, pp. 306-360
-
-
Pratt, W.B.1
Toft, D.O.2
-
11
-
-
0037315208
-
Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery
-
Pratt WB, Toft DO: Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery. Exp Biol Med (Maywood) 2003;228:111-133
-
(2003)
Exp Biol Med (Maywood)
, vol.228
, pp. 111-133
-
-
Pratt, W.B.1
Toft, D.O.2
-
12
-
-
3142520021
-
Glucocorticoid and mineralocorticoid receptors and associated diseases
-
Kino T, Chrousos GP: Glucocorticoid and mineralocorticoid receptors and associated diseases. Essays Biochem 2004;40:137-155
-
(2004)
Essays Biochem
, vol.40
, pp. 137-155
-
-
Kino, T.1
Chrousos, G.P.2
-
13
-
-
0033600936
-
The dominant negative activity of the human glucocorticoid receptor beta isoform. Specificity and mechanisms of action
-
Oakley RH, Jewell CM, Yudt MR, Bofetiado DM, Cidlowski JA: The dominant negative activity of the human glucocorticoid receptor beta isoform. Specificity and mechanisms of action. J Biol Chem 1999;274:27857- 27866
-
(1999)
J Biol Chem
, vol.274
, pp. 27857-27866
-
-
Oakley, R.H.1
Jewell, C.M.2
Yudt, M.R.3
Bofetiado, D.M.4
Cidlowski, J.A.5
-
14
-
-
18444405534
-
Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition
-
Bledsoe RK, Montana VG, Stanley TB, Delves CJ, Apolito CJ, McKee DD, Consler TG, Parks DJ, Stewart EL, Willson TM, Lambert MH, Moore JT, Pearce KH, Xu HE: Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition. Cell 2002;110:93-105
-
(2002)
Cell
, vol.110
, pp. 93-105
-
-
Bledsoe, R.K.1
Montana, V.G.2
Stanley, T.B.3
Delves, C.J.4
Apolito, C.J.5
McKee, D.D.6
Consler, T.G.7
Parks, D.J.8
Stewart, E.L.9
Willson, T.M.10
Lambert, M.H.11
Moore, J.T.12
Pearce, K.H.13
Xu, H.E.14
-
15
-
-
0035523135
-
The expression of glucocorticoid receptor beta messenger RNA in peripheral white blood cells of hormone-resistant nephrotic syndrome patients
-
Liu Y SL, Li B: The expression of glucocorticoid receptor beta messenger RNA in peripheral white blood cells of hormone-resistant nephrotic syndrome patients. Zhonghua Nei Ke Za Zhi 2001;40:725-728
-
(2001)
Zhonghua Nei Ke Za Zhi
, vol.40
, pp. 725-728
-
-
Liu Y, S.L.1
Li, B.2
-
16
-
-
0036731695
-
Increased glucocorticoid receptor Beta expression converts mouse hybridoma cells to a corticosteroid-insensitive phenotype
-
Hauk PJ, Goleva E, Strickland I, Vottero A, Chrousos GP, Kisich KO, Leung DY: Increased glucocorticoid receptor Beta expression converts mouse hybridoma cells to a corticosteroid-insensitive phenotype. Am J Respir Cell Mol Biol 2002;27:361-367
-
(2002)
Am J Respir Cell Mol Biol
, vol.27
, pp. 361-367
-
-
Hauk, P.J.1
Goleva, E.2
Strickland, I.3
Vottero, A.4
Chrousos, G.P.5
Kisich, K.O.6
Leung, D.Y.7
-
17
-
-
0035810930
-
Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative beta isoform: A mechanism for the generation of glucocorticoid resistance
-
Webster JC, Oakley RH, Jewell CM, Cidlowski JA: Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative beta isoform: A mechanism for the generation of glucocorticoid resistance. Proc Natl Acad Sci U S A 2001;98:6865-6870
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 6865-6870
-
-
Webster, J.C.1
Oakley, R.H.2
Jewell, C.M.3
Cidlowski, J.A.4
-
18
-
-
0037979126
-
Molecular origins for the dominant negative function of human glucocorticoid receptor beta
-
Yudt MR, Jewell CM, Bienstock RJ, Cidlowski JA: Molecular origins for the dominant negative function of human glucocorticoid receptor beta. Mol Cell Biol 2003;23:4319-4330
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4319-4330
-
-
Yudt, M.R.1
Jewell, C.M.2
Bienstock, R.J.3
Cidlowski, J.A.4
-
19
-
-
70349881524
-
Human glucocorticoid receptor isoform β recent understanding of its potential implications in physiology and pathophysiology
-
Kino T, Su YA, Chrousos GP: Human glucocorticoid receptor isoform β: Recent understanding of its potential implications in physiology and pathophysiology. Cell Mol Life Sci 2009;66:3435-3448
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 3435-3448
-
-
Kino, T.1
Su, Y.A.2
Chrousos, G.P.3
-
20
-
-
0036013805
-
Overexpression of the human glucocorticoid receptor alpha and beta isoforms inhibits AP-1 and NF-kappaB activities hormone independently
-
Gougat C, Jaffuel D, Gagliardo R, Henriquet C, Bousquet J, Demoly P, Mathieu M: Overexpression of the human glucocorticoid receptor alpha and beta isoforms inhibits AP-1 and NF-kappaB activities hormone independently. J Mol Med (Berl) 2002;80:309-318
-
(2002)
J Mol Med (Berl)
, vol.80
, pp. 309-318
-
-
Gougat, C.1
Jaffuel, D.2
Gagliardo, R.3
Henriquet, C.4
Bousquet, J.5
Demoly, P.6
Mathieu, M.7
-
21
-
-
0036794281
-
Nuclear export of glucocorticoid receptor is enhanced by c-Jun N-terminal kinase-mediated phosphorylation
-
Itoh M, Adachi M, Yasui H, Takekawa M, Tanaka H, Imai K: Nuclear export of glucocorticoid receptor is enhanced by c-Jun N-terminal kinase-mediated phosphorylation. Mol Endocrinol 2002;16:2382-2392
-
(2002)
Mol Endocrinol
, vol.16
, pp. 2382-2392
-
-
Itoh, M.1
Adachi, M.2
Yasui, H.3
Takekawa, M.4
Tanaka, H.5
Imai, K.6
-
22
-
-
0030998260
-
Mitogen-Activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor
-
Krstic MD, Rogatsky I, Yamamoto KR, Garabedian MJ: Mitogen-Activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor. Mol Cell Biol 1997;17:3947-3954
-
(1997)
Mol Cell Biol
, vol.17
, pp. 3947-3954
-
-
Krstic, M.D.1
Rogatsky, I.2
Yamamoto, K.R.3
Garabedian, M.J.4
-
24
-
-
33748430642
-
Direct effects of dexamethasone on human podocytes
-
Xing CY, Saleem MA, Coward RJ, Ni L, Witherden IR, Mathieson PW: Direct effects of dexamethasone on human podocytes. Kidney Int 2006;70:1038-1045
-
(2006)
Kidney Int
, vol.70
, pp. 1038-1045
-
-
Xing, C.Y.1
Saleem, M.A.2
Coward, R.J.3
Ni, L.4
Witherden, I.R.5
Mathieson, P.W.6
-
25
-
-
33644801094
-
Dexamethasone Prevents Podocyte Apoptosis Induced by Puromycin Aminonucleoside: Role of p53 and Bcl-2-Related Family Proteins
-
Wada T: Dexamethasone Prevents Podocyte Apoptosis Induced by Puromycin Aminonucleoside: Role of p53 and Bcl-2-Related Family Proteins. J Am Soc Nephrol 2005;16:2615-2625
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 2615-2625
-
-
Wada, T.1
-
26
-
-
32844469380
-
Glucocorticoids protect and enhance recovery of cultured murine podocytes via actin filament stabilization
-
Ransom RF, Lam NG, Hallett MA, Atkinson SJ, Smoyer WE: Glucocorticoids protect and enhance recovery of cultured murine podocytes via actin filament stabilization. Kidney Int 2005;68:2473-2483
-
(2005)
Kidney Int
, vol.68
, pp. 2473-2483
-
-
Ransom, R.F.1
Lam, N.G.2
Hallett, M.A.3
Atkinson, S.J.4
Smoyer, W.E.5
-
27
-
-
84878665612
-
Podocyte repopulation by renal progenitor cells following glucocorticoids treatment in experimental FSGS
-
Zhang J, Pippin JW, Krofft RD, Naito S, Liu ZH, Shankland SJ: Podocyte repopulation by renal progenitor cells following glucocorticoids treatment in experimental FSGS. Am J Physiol Renal Physiol 2013;304:F1375-F1389
-
(2013)
Am J Physiol Renal Physiol
, Issue.304
-
-
Zhang, J.1
Pippin, J.W.2
Krofft, R.D.3
Naito, S.4
Liu, Z.H.5
Shankland, S.J.6
-
28
-
-
79961132981
-
Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis
-
Wei C, El Hindi S, Li J, Fornoni A, Goes N, Sageshima J, Maiguel D, Karumanchi SA, Yap HK, Saleem M, Zhang Q, Nikolic B, Chaudhuri A, Daftarian P, Salido E, Torres A, Salifu M, Sarwal MM, Schaefer F, Morath C, Schwenger V, Zeier M, Gupta V, Roth D, Rastaldi MP, Burke G, Ruiz P, Reiser J: Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis. Nat Med 2011;17:952-960
-
(2011)
Nat Med
, Issue.17
, pp. 952-960
-
-
Wei, C.1
El Hindi, S.2
Li, J.3
Fornoni, A.4
Goes, N.5
Sageshima, J.6
Maiguel, D.7
Karumanchi, S.A.8
Yap, H.K.9
Saleem, M.10
Zhang, Q.11
Nikolic, B.12
Chaudhuri, A.13
Daftarian, P.14
Salido, E.15
Torres, A.16
Salifu, M.17
Sarwal, M.M.18
Schaefer, F.19
Morath, C.20
Schwenger, V.21
Zeier, M.22
Gupta, V.23
Roth, D.24
Rastaldi, M.P.25
Burke, G.26
Ruiz, P.27
Reiser, J.28
more..
-
29
-
-
84874629601
-
Current and emerging treatments for idiopathic focal and segmental glomerulosclerosis in adults
-
Ponticelli C, Graziani G: Current and emerging treatments for idiopathic focal and segmental glomerulosclerosis in adults. Expert Rev Clin Immunol 2013;9:251-261
-
(2013)
Expert Rev Clin Immunol
, Issue.9
, pp. 251-261
-
-
Ponticelli, C.1
Graziani, G.2
-
30
-
-
51349162919
-
The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A
-
Faul C, Donnelly M, Merscher-Gomez S, Chang YH, Franz S, Delfgaauw J, Chang JM, Choi HY, Campbell KN, Kim K, Reiser J, Mundel P: The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A. Nat Med 2008;14:931-938
-
(2008)
Nat Med
, vol.14
, pp. 931-938
-
-
Faul, C.1
Donnelly, M.2
Merscher-Gomez, S.3
Chang, Y.H.4
Franz, S.5
Delfgaauw, J.6
Chang, J.M.7
Choi, H.Y.8
Campbell, K.N.9
Kim, K.10
Reiser, J.11
Mundel, P.12
-
31
-
-
0032015551
-
Positionally cloned gene for a novel glomerular protein-nephrin-is mutated in congenital nephrotic syndrome
-
Kestila M, Lenkkeri U, Mannikko M, Lamerdin J, McCready P, Putaala H, Ruotsalainen V, Morita T, Nissinen M, Herva R, Kashtan CE, Peltonen L, Holmberg C, Olsen A, Tryggvason K: Positionally cloned gene for a novel glomerular protein-nephrin-is mutated in congenital nephrotic syndrome. Mol Cell 1998;1:575- 582
-
(1998)
Mol Cell
, vol.1
, pp. 575-582
-
-
Kestila, M.1
Lenkkeri, U.2
Mannikko, M.3
Lamerdin, J.4
McCready, P.5
Putaala, H.6
Ruotsalainen, V.7
Morita, T.8
Nissinen, M.9
Herva, R.10
Kashtan, C.E.11
Peltonen, L.12
Holmberg, C.13
Olsen, A.14
Tryggvason, K.15
-
32
-
-
0035510132
-
Defective nephrin trafficking caused by missense mutations in the NPHS1 gene: Insight into the mechanisms of congenital nephrotic syndrome
-
Liu L, Done SC, Khoshnoodi J, Bertorello A, Wartiovaara J, Berggren PO, Tryggvason K: Defective nephrin trafficking caused by missense mutations in the NPHS1 gene: Insight into the mechanisms of congenital nephrotic syndrome. Hum Mol Genet 2001;10:2637-2644
-
(2001)
Hum Mol Genet
, vol.10
, pp. 2637-2644
-
-
Liu, L.1
Done, S.C.2
Khoshnoodi, J.3
Bertorello, A.4
Wartiovaara, J.5
Berggren, P.O.6
Tryggvason, K.7
-
33
-
-
0344413020
-
Nephrin promotes cell-cell adhesion through homophilic interactions
-
Khoshnoodi J, Sigmundsson K, Ofverstedt LG, Skoglund U, Obrink B, Wartiovaara J, Tryggvason K: Nephrin promotes cell-cell adhesion through homophilic interactions. Am J Pathol 2003;163:2337-2346
-
(2003)
Am J Pathol
, vol.163
, pp. 2337-2346
-
-
Khoshnoodi, J.1
Sigmundsson, K.2
Ofverstedt, L.G.3
Skoglund, U.4
Obrink, B.5
Wartiovaara, J.6
Tryggvason, K.7
-
34
-
-
0033536599
-
Congenital nephrotic syndrome in mice lacking CD2-Associated protein
-
Shih NY, Li J, Karpitskii V, Nguyen A, Dustin ML, Kanagawa O, Miner JH, Shaw AS: Congenital nephrotic syndrome in mice lacking CD2-Associated protein. Science 1999;286:312-315
-
(1999)
Science
, vol.286
, pp. 312-315
-
-
Shih, N.Y.1
Li, J.2
Karpitskii, V.3
Nguyen, A.4
Dustin, M.L.5
Kanagawa, O.6
Miner, J.H.7
Shaw, A.S.8
-
35
-
-
33751084075
-
Molecular basis of the glomerular filtration: Nephrin and the emerging protein complex at the podocyte slit diaphragm
-
Patari-Sampo A, Ihalmo P, Holthofer H: Molecular basis of the glomerular filtration: Nephrin and the emerging protein complex at the podocyte slit diaphragm. Ann Med 2006;38:483-492
-
(2006)
Ann Med
, vol.38
, pp. 483-492
-
-
Patari-Sampo, A.1
Ihalmo, P.2
Holthofer, H.3
-
36
-
-
77956259962
-
Nineteen novel NPHS1 mutations in a worldwide cohort of patients with congenital nephrotic syndrome (CNS)
-
Schoeb DS, Chernin G, Heeringa SF, Matejas V, Held S, Vega-Warner V, Bockenhauer D, Vlangos CN, Moorani KN, Neuhaus TJ, Kari JA, MacDonald J, Saisawat P, Ashraf S, Ovunc B, Zenker M, Hildebrandt F: Nineteen novel NPHS1 mutations in a worldwide cohort of patients with congenital nephrotic syndrome (CNS). Nephrol Dial Transplant 2010;25:2970-2976
-
(2010)
Nephrol Dial Transplant
, Issue.25
, pp. 2970-2976
-
-
Schoeb, D.S.1
Chernin, G.2
Heeringa, S.F.3
Matejas, V.4
Held, S.5
Vega-Warner, V.6
Bockenhauer, D.7
Vlangos, C.N.8
Moorani, K.N.9
Neuhaus, T.J.10
Kari, J.A.11
MacDonald, J.12
Saisawat, P.13
Ashraf, S.14
Ovunc, B.15
Zenker, M.16
Hildebrandt, F.17
-
37
-
-
54049142085
-
Antignac C: Nephrin mutations can cause childhood-onset steroid-resistant nephrotic syndrome
-
Philippe A, Nevo F, Esquivel EL, Reklaityte D, Gribouval O, Tete MJ, Loirat C, Dantal J, Fischbach M, Pouteil- Noble C, Decramer S, Hoehne M, Benzing T, Charbit M, Niaudet P, Antignac C: Nephrin mutations can cause childhood-onset steroid-resistant nephrotic syndrome. J Am Soc Nephrol 2008;19:1871-1878
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 1871-1878
-
-
Philippe, A.1
Nevo, F.2
Esquivel, E.L.3
Reklaityte, D.4
Gribouval, O.5
Tete, M.J.6
Loirat, C.7
Dantal, J.8
Fischbach, M.9
Pouteil- Noble, C.10
Decramer, S.11
Hoehne, M.12
Benzing, T.13
Charbit, M.14
Niaudet, P.15
-
38
-
-
71149119200
-
Nephrin mutations cause childhood- And adult-onset focal segmental glomerulosclerosis
-
Santin S, Garcia-Maset R, Ruiz P, Gimenez I, Zamora I, Pena A, Madrid A, Camacho JA, Fraga G, Sanchez- Moreno A, Cobo MA, Bernis C, Ortiz A, de Pablos AL, Pintos G, Justa ML, Hidalgo-Barquero E, Fernandez- Llama P, Ballarin J, Ars E, Torra R: Nephrin mutations cause childhood- And adult-onset focal segmental glomerulosclerosis. Kidney Int 2009;76:1268-1276
-
(2009)
Kidney Int
, vol.76
, pp. 1268-1276
-
-
Santin, S.1
Garcia-Maset, R.2
Ruiz, P.3
Gimenez, I.4
Zamora, I.5
Pena, A.6
Madrid, A.7
Camacho, J.A.8
Fraga, G.9
Sanchez- Moreno, A.10
Cobo, M.A.11
Bernis, C.12
Ortiz, A.13
De Pablos, A.L.14
Pintos, G.15
Justa, M.L.16
Hidalgo-Barquero, E.17
Fernandez- Llama, P.18
Ballarin, J.19
Ars, E.20
Torra, R.21
more..
-
39
-
-
84860787585
-
Mutation Analysis of NPHS1 in a Worldwide Cohort of Congenital Nephrotic Syndrome Patients
-
Ovunc B, Ashraf S, Vega-Warner V, Bockenhauer D, Soliman Elshakhs NA, Joseph M, Hildebrandt F: Mutation Analysis of NPHS1 in a Worldwide Cohort of Congenital Nephrotic Syndrome Patients. Nephron Clin Pract 2012;120:c139-c146
-
(2012)
Nephron Clin Pract
, Issue.120
-
-
Ovunc, B.1
Ashraf, S.2
Vega-Warner, V.3
Bockenhauer, D.4
Soliman Elshakhs, N.A.5
Joseph, M.6
Hildebrandt, F.7
-
40
-
-
54149117148
-
Thirteen novel NPHS1 mutations in a large cohort of children with congenital nephrotic syndrome
-
Heeringa SF, Vlangos CN, Chernin G, Hinkes B, Gbadegesin R, Liu J, Hoskins BE, Ozaltin F, Hildebrandt F: Thirteen novel NPHS1 mutations in a large cohort of children with congenital nephrotic syndrome. Nephrol Dial Transplant 2008;23:3527-3533
-
(2008)
Nephrol Dial Transplant
, vol.23
, pp. 3527-3533
-
-
Heeringa, S.F.1
Vlangos, C.N.2
Chernin, G.3
Hinkes, B.4
Gbadegesin, R.5
Liu, J.6
Hoskins, B.E.7
Ozaltin, F.8
Hildebrandt, F.9
-
41
-
-
34247542605
-
A familial childhood-onset relapsing nephrotic syndrome
-
Kitamura A, Tsukaguchi H, Hiramoto R, Shono A, Doi T, Kagami S, Iijima K: A familial childhood-onset relapsing nephrotic syndrome. Kidney Int 2007;71:946-951
-
(2007)
Kidney Int
, vol.71
, pp. 946-951
-
-
Kitamura, A.1
Tsukaguchi, H.2
Hiramoto, R.3
Shono, A.4
Doi, T.5
Kagami, S.6
Iijima, K.7
-
42
-
-
3042623796
-
Defective trafficking of nephrin missense mutants rescued by a chemical chaperone
-
Liu XL, Done SC, Yan K, Kilpelainen P, Pikkarainen T, Tryggvason K: Defective trafficking of nephrin missense mutants rescued by a chemical chaperone. J Am Soc Nephrol 2004;15:1731-1738
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 1731-1738
-
-
Liu, X.L.1
Done, S.C.2
Yan, K.3
Kilpelainen, P.4
Pikkarainen, T.5
Tryggvason, K.6
-
43
-
-
0037084569
-
Genotype/phenotype correlations of NPHS1 and NPHS2 mutations in nephrotic syndrome advocate a functional interrelationship in glomerular filtration
-
Koziell A, Grech V, Hussain S, Lee G, Lenkkeri U, Tryggvason K, Scambler P: Genotype/phenotype correlations of NPHS1 and NPHS2 mutations in nephrotic syndrome advocate a functional interrelationship in glomerular filtration. Hum Mol Genet 2002;11:379-388
-
(2002)
Hum Mol Genet
, vol.11
, pp. 379-388
-
-
Koziell, A.1
Grech, V.2
Hussain, S.3
Lee, G.4
Lenkkeri, U.5
Tryggvason, K.6
Scambler, P.7
-
44
-
-
10744225757
-
In situ evaluation of podocin in normal and glomerular diseases
-
Horinouchi I, Nakazato H, Kawano T, Iyama K, Furuse A, Arizono K, Machida J, Sakamoto T, Endo F, Hattori S: In situ evaluation of podocin in normal and glomerular diseases. Kidney Int 2003;64:2092-2099
-
(2003)
Kidney Int
, vol.64
, pp. 2092-2099
-
-
Horinouchi, I.1
Nakazato, H.2
Kawano, T.3
Iyama, K.4
Furuse, A.5
Arizono, K.6
Machida, J.7
Sakamoto, T.8
Endo, F.9
Hattori, S.10
-
45
-
-
0036144232
-
Podocin localizes in the kidney to the slit diaphragm area
-
Roselli S, Gribouval O, Boute N, Sich M, Benessy F, Attie T, Gubler MC, Antignac C: Podocin localizes in the kidney to the slit diaphragm area. Am J Pathol 2002;160:131-139
-
(2002)
Am J Pathol
, vol.160
, pp. 131-139
-
-
Roselli, S.1
Gribouval, O.2
Boute, N.3
Sich, M.4
Benessy, F.5
Attie, T.6
Gubler, M.C.7
Antignac, C.8
-
46
-
-
0035210324
-
Podocin, a raftassociated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin
-
Schwarz K, Simons M, Reiser J, Saleem MA, Faul C, Kriz W, Shaw AS, Holzman LB, Mundel P: Podocin, a raftassociated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin. J Clin Invest 2001;108:1621-1629
-
(2001)
J Clin Invest
, vol.108
, pp. 1621-1629
-
-
Schwarz, K.1
Simons, M.2
Reiser, J.3
Saleem, M.A.4
Faul, C.5
Kriz, W.6
Shaw, A.S.7
Holzman, L.B.8
Mundel, P.9
-
47
-
-
0346121526
-
Molecular basis of the functional podocin-nephrin complex: Mutations in the NPHS2 gene disrupt nephrin targeting to lipid raft microdomains
-
Huber TB, Simons M, Hartleben B, Sernetz L, Schmidts M, Gundlach E, Saleem MA, Walz G, Benzing T: Molecular basis of the functional podocin-nephrin complex: Mutations in the NPHS2 gene disrupt nephrin targeting to lipid raft microdomains. Hum Mol Genet 2003;12:3397-3405
-
(2003)
Hum Mol Genet
, vol.12
, pp. 3397-3405
-
-
Huber, T.B.1
Simons, M.2
Hartleben, B.3
Sernetz, L.4
Schmidts, M.5
Gundlach, E.6
Saleem, M.A.7
Walz, G.8
Benzing, T.9
-
48
-
-
53949115449
-
Steroid-resistant nephrotic syndrome
-
Kitamura A, Tsukaguchi H, Maruyama K, Shono A, Iijima K, Kagami S, Doi T: Steroid-resistant nephrotic syndrome. Kidney Int 2008;74:1209-1215
-
(2008)
Kidney Int
, vol.74
, pp. 1209-1215
-
-
Kitamura, A.1
Tsukaguchi, H.2
Maruyama, K.3
Shono, A.4
Iijima, K.5
Kagami, S.6
Doi, T.7
-
49
-
-
33645403446
-
NPHS2 gene, nephrotic syndrome and focal segmental glomerulosclerosis: A HuGE review
-
Franceschini N, North KE, Kopp JB, McKenzie L, Winkler C: NPHS2 gene, nephrotic syndrome and focal segmental glomerulosclerosis: A HuGE review. Genet Med 2006;8:63-75
-
(2006)
Genet Med
, vol.8
, pp. 63-75
-
-
Franceschini, N.1
North, K.E.2
Kopp, J.B.3
McKenzie, L.4
Winkler, C.5
-
50
-
-
0036897388
-
NPHS2 mutations in late-onset focal segmental glomerulosclerosis: R229Q is a common disease-Associated allele
-
Tsukaguchi H, Sudhakar A, Le TC, Nguyen T, Yao J, Schwimmer JA, Schachter AD, Poch E, Abreu PF, Appel GB, Pereira AB, Kalluri R, Pollak MR: NPHS2 mutations in late-onset focal segmental glomerulosclerosis: R229Q is a common disease-Associated allele. J Clin Invest 2002;110:1659-1666
-
(2002)
J Clin Invest
, vol.110
, pp. 1659-1666
-
-
Tsukaguchi, H.1
Sudhakar, A.2
Le, T.C.3
Nguyen, T.4
Yao, J.5
Schwimmer, J.A.6
Schachter, A.D.7
Poch, E.8
Abreu, P.F.9
Appel, G.B.10
Pereira, A.B.11
Kalluri, R.12
Pollak, M.R.13
-
51
-
-
10744226566
-
Patients with mutations in NPHS2 (podocin) do not respond to standard steroid treatment of nephrotic syndrome
-
Ruf RG, Lichtenberger A, Karle SM, Haas JP, Anacleto FE, Schultheiss M, Zalewski I, Imm A, Ruf EM, Mucha B, Bagga A, Neuhaus T, Fuchshuber A, Bakkaloglu A, Hildebrandt F: Patients with mutations in NPHS2 (podocin) do not respond to standard steroid treatment of nephrotic syndrome. J Am Soc Nephrol 2004;15:722-732
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 722-732
-
-
Ruf, R.G.1
Lichtenberger, A.2
Karle, S.M.3
Haas, J.P.4
Anacleto, F.E.5
Schultheiss, M.6
Zalewski, I.7
Imm, A.8
Ruf, E.M.9
Mucha, B.10
Bagga, A.11
Neuhaus, T.12
Fuchshuber, A.13
Bakkaloglu, A.14
Hildebrandt, F.15
-
52
-
-
0036151614
-
Novel mutations in NPHS2 detected in both familial and sporadic steroid-resistant nephrotic syndrome
-
Karle SM, Uetz B, Ronner V, Glaeser L, Hildebrandt F, Fuchshuber A: Novel mutations in NPHS2 detected in both familial and sporadic steroid-resistant nephrotic syndrome. J Am Soc Nephrol 2002;13:388-393
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 388-393
-
-
Karle, S.M.1
Uetz, B.2
Ronner, V.3
Glaeser, L.4
Hildebrandt, F.5
Fuchshuber, A.6
-
53
-
-
79951873276
-
Clinical Value of NPHS2 Analysis in Early- And Adult-Onset Steroid-Resistant Nephrotic Syndrome
-
Santin S, Tazon-Vega B, Silva I, Cobo MA, Gimenez I, Ruiz P, Garcia-Maset R, Ballarin J, Torra R, Ars E: Clinical Value of NPHS2 Analysis in Early- And Adult-Onset Steroid-Resistant Nephrotic Syndrome. Clin J Am Soc Nephrol 2010;6:344-354
-
(2010)
Clin J Am Soc Nephrol
, Issue.6
, pp. 344-354
-
-
Santin, S.1
Tazon-Vega, B.2
Silva, I.3
Cobo, M.A.4
Gimenez, I.5
Ruiz, P.6
Garcia-Maset, R.7
Ballarin, J.8
Torra, R.9
Ars, E.10
-
54
-
-
1542318905
-
Podocin and Nephrotic Syndrome: Implications for the Clinician
-
Niaudet P: Podocin and Nephrotic Syndrome: Implications for the Clinician. J Am Soc Nephrol 2004;15:832-834
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 832-834
-
-
Niaudet, P.1
-
55
-
-
62349123713
-
Clinical and epidemiological assessment of steroid-resistant nephrotic syndrome associated with the NPHS2 R229Q variant
-
Machuca E, Hummel A, Nevo F, Dantal J, Martinez F, Al-Sabban E, Baudouin V, Abel L, Grünfeld J-P, Antignac C: Clinical and epidemiological assessment of steroid-resistant nephrotic syndrome associated with the NPHS2 R229Q variant. Kidney Int 2009;75:727-735
-
(2009)
Kidney Int
, vol.75
, pp. 727-735
-
-
Machuca, E.1
Hummel, A.2
Nevo, F.3
Dantal, J.4
Martinez, F.5
Al-Sabban, E.6
Baudouin, V.7
Abel, L.8
Grünfeld, J.-P.9
Antignac, C.10
-
56
-
-
3242795082
-
NPHS2 mutation analysis shows genetic heterogeneity of steroid-resistant nephrotic syndrome and low post-transplant recurrence
-
Weber S, Gribouval O, Esquivel EL, Moriniere V, Tete MJ, Legendre C, Niaudet P, Antignac C: NPHS2 mutation analysis shows genetic heterogeneity of steroid-resistant nephrotic syndrome and low post-transplant recurrence. Kidney Int 2004;66:571-579
-
(2004)
Kidney Int
, vol.66
, pp. 571-579
-
-
Weber, S.1
Gribouval, O.2
Esquivel, E.L.3
Moriniere, V.4
Tete, M.J.5
Legendre, C.6
Niaudet, P.7
Antignac, C.8
-
57
-
-
0034051681
-
Mutations in ACTN4, encoding alpha-Actinin-4, cause familial focal segmental glomerulosclerosis
-
Kaplan JM, Kim SH, North KN, Rennke H, Correia LA, Tong HQ, Mathis BJ, Rodriguez-Perez JC, Allen PG, Beggs AH, Pollak MR: Mutations in ACTN4, encoding alpha-Actinin-4, cause familial focal segmental glomerulosclerosis. Nat Genet 2000;24:251-256
-
(2000)
Nat Genet
, vol.24
, pp. 251-256
-
-
Kaplan, J.M.1
Kim, S.H.2
North, K.N.3
Rennke, H.4
Correia, L.A.5
Tong, H.Q.6
Mathis, B.J.7
Rodriguez-Perez, J.C.8
Allen, P.G.9
Beggs, A.H.10
Pollak, M.R.11
-
58
-
-
0032559853
-
Actinin-4, a novel actin-bundling protein associated with cell motility and cancer invasion
-
Honda K, Yamada T, Endo R, Ino Y, Gotoh M, Tsuda H, Yamada Y, Chiba H, Hirohashi S: Actinin-4, a novel actin-bundling protein associated with cell motility and cancer invasion. J Cell Biol 1998;140:1383-1393
-
(1998)
J Cell Biol
, vol.140
, pp. 1383-1393
-
-
Honda, K.1
Yamada, T.2
Endo, R.3
Ino, Y.4
Gotoh, M.5
Tsuda, H.6
Yamada, Y.7
Chiba, H.8
Hirohashi, S.9
-
59
-
-
0345282940
-
Actin filament organization of foot processes in rat podocytes
-
Ichimura K, Kurihara H, Sakai T: Actin filament organization of foot processes in rat podocytes. J Histochem Cytochem 2003;51:1589-1600
-
(2003)
J Histochem Cytochem
, vol.51
, pp. 1589-1600
-
-
Ichimura, K.1
Kurihara, H.2
Sakai, T.3
-
60
-
-
84858773146
-
Podocyte Injury Associated with Mutant α-Actinin-4
-
Cybulsky AV, Kennedy CRJ: Podocyte Injury Associated with Mutant α-Actinin-4. J Signal Transduct 2011;2011:1-11
-
(2011)
J Signal Transduct
, Issue.2011
, pp. 1-11
-
-
Cybulsky, A.V.1
Kennedy, C.R.J.2
-
61
-
-
16644399642
-
Alpha-Actinin-4-mediated FSGS: An inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein
-
Yao J, Le TC, Kos CH, Henderson JM, Allen PG, Denker BM, Pollak MR: Alpha-Actinin-4-mediated FSGS: An inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein. PLoS Biol 2004;2:e167
-
(2004)
PLoS Biol
, vol.2
-
-
Le Yao, J.T.C.1
Kos, C.H.2
Henderson, J.M.3
Allen, P.G.4
Denker, B.M.5
Pollak, M.R.6
-
62
-
-
80052188370
-
Actinin-4 and CLP36 Protein Deficiencies Contribute to Podocyte Defects in Multiple Human Glomerulopathies
-
Liu Z, Blattner SM, Tu Y, Tisherman R, Wang JH, Rastaldi MP, Kretzler M, Wu C: -Actinin-4 and CLP36 Protein Deficiencies Contribute to Podocyte Defects in Multiple Human Glomerulopathies. J Biol Chem 2011;286:30795-30805
-
(2011)
J Biol Chem
, Issue.286
, pp. 30795-30805
-
-
Liu, Z.1
Blattner, S.M.2
Tu, Y.3
Tisherman, R.4
Wang, J.H.5
Rastaldi, M.P.6
Kretzler, M.7
Wu, C.8
-
63
-
-
33645946089
-
Mutational and Biological Analysis of alpha-Actinin-4 in focal segmental glomerulosclerosis
-
Weins A, Kenlan P, Herbert S, Le TC, Villegas I, Kaplan BS, Appel GB, Pollak MR: Mutational and Biological Analysis of alpha-Actinin-4 in focal segmental glomerulosclerosis. J Am Soc Nephrol 2005;16:3694-3701
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 3694-3701
-
-
Weins, A.1
Kenlan, P.2
Herbert, S.3
Le, T.C.4
Villegas, I.5
Kaplan, B.S.6
Appel, G.B.7
Pollak, M.R.8
-
64
-
-
0038819061
-
Mice deficient in alpha-Actinin-4 have severe glomerular disease
-
Kos CH, Le TC, Sinha S, Henderson JM, Kim SH, Sugimoto H, Kalluri R, Gerszten RE, Pollak MR: Mice deficient in alpha-Actinin-4 have severe glomerular disease. J Clin Invest 2003;111:1683-1690
-
(2003)
J Clin Invest
, vol.111
, pp. 1683-1690
-
-
Kos, C.H.1
Le, T.C.2
Sinha, S.3
Henderson, J.M.4
Kim, S.H.5
Sugimoto, H.6
Kalluri, R.7
Gerszten, R.E.8
Pollak, M.R.9
-
65
-
-
33847001656
-
Alpha-Actinin-4 is required for normal podocyte adhesion
-
Dandapani SV, Sugimoto H, Matthews BD, Kolb RJ, Sinha S, Gerszten RE, Zhou J, Ingber DE, Kalluri R, Pollak MR: Alpha-Actinin-4 is required for normal podocyte adhesion. J Biol Chem 2007;282:467-477
-
(2007)
J Biol Chem
, vol.282
, pp. 467-477
-
-
Dandapani, S.V.1
Sugimoto, H.2
Matthews, B.D.3
Kolb, R.J.4
Sinha, S.5
Gerszten, R.E.6
Zhou, J.7
Ingber, D.E.8
Kalluri, R.9
Pollak, M.R.10
-
66
-
-
43049085942
-
Familial focal segmental glomerulosclerosis associated with an ACTN4 mutation and paternal germline mosaicism
-
Choi HJ, Lee BH, Cho HY, Moon KC, Ha IS, Nagata M, Choi Y, Cheong HI: Familial focal segmental glomerulosclerosis associated with an ACTN4 mutation and paternal germline mosaicism. Am J Kidney Dis 2008;51:834-838
-
(2008)
Am J Kidney Dis
, vol.51
, pp. 834-838
-
-
Choi, H.J.1
Lee, B.H.2
Cho, H.Y.3
Moon, K.C.4
Ha, I.S.5
Nagata, M.6
Choi, Y.7
Cheong, H.I.8
-
67
-
-
0032483559
-
A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts
-
Dustin ML, Olszowy MW, Holdorf AD, Li J, Bromley S, Desai N, Widder P, Rosenberger F, van der Merwe PA, Allen PM, Shaw AS: A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts. Cell 1998;94:667-677
-
(1998)
Cell
, vol.94
, pp. 667-677
-
-
Dustin, M.L.1
Olszowy, M.W.2
Holdorf, A.D.3
Li, J.4
Bromley, S.5
Desai, N.6
Widder, P.7
Rosenberger, F.8
Van Der Merwe, P.A.9
Allen, P.M.10
Shaw, A.S.11
-
68
-
-
0038788840
-
Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling
-
Huber TB, Hartleben B, Kim J, Schmidts M, Schermer B, Keil A, Egger L, Lecha RL, Borner C, Pavenstadt H, Shaw AS, Walz G, Benzing T: Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling. Mol Cell Biol 2003;23:4917-4928
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4917-4928
-
-
Huber, T.B.1
Hartleben, B.2
Kim, J.3
Schmidts, M.4
Schermer, B.5
Keil, A.6
Egger, L.7
Lecha, R.L.8
Borner, C.9
Pavenstadt, H.10
Shaw, A.S.11
Walz, G.12
Benzing, T.13
-
69
-
-
34547213485
-
Nuclear relocation of the nephrin and CD2AP-binding protein dendrin promotes apoptosis of podocytes
-
Asanuma K CK, Kim K, Faul C, Mundel P: Nuclear relocation of the nephrin and CD2AP-binding protein dendrin promotes apoptosis of podocytes. Proc Natl Acad Sci U S A 2007;104:10134-10139
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 10134-10139
-
-
Asanuma K, C.K.1
Kim, K.2
Faul, C.3
Mundel, P.4
-
70
-
-
4344685529
-
A Novel Role for the Adaptor Molecule CD2-Associated Protein in Transforming Growth Factor-β-induced Apoptosis
-
Schiffer M MP, Shaw AS, Böttinger EP: A Novel Role for the Adaptor Molecule CD2-Associated Protein in Transforming Growth Factor-β-induced Apoptosis. J Biol Chem 2004;279:37004-37012
-
(2004)
J Biol Chem
, vol.279
, pp. 37004-37012
-
-
Schiffer M, M.P.1
Shaw, A.S.2
Böttinger, E.P.3
-
71
-
-
0038136885
-
CD2-Associated protein haploinsufficiency is linked to glomerular disease susceptibility
-
Kim JM, Wu H, Green G, Winkler CA, Kopp JB, Miner JH, Unanue ER, Shaw AS: CD2-Associated protein haploinsufficiency is linked to glomerular disease susceptibility. Science 2003;300:1298-1300
-
(2003)
Science
, vol.300
, pp. 1298-1300
-
-
Kim, J.M.1
Wu, H.2
Green, G.3
Winkler, C.A.4
Kopp, J.B.5
Miner, J.H.6
Unanue, E.R.7
Shaw, A.S.8
-
72
-
-
80053439688
-
CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival
-
Yaddanapudi S, Altintas MM, Kistler AD, Fernandez I, Möller CC, Wei C, Peev V, Flesche JB, Forst A-L, Li J, Patrakka J, Xiao Z, Grahammer F, Schiffer M, Lohmüller T, Reinheckel T, Gu C, Huber TB, Ju W, Bitzer M, Rastaldi MP, Ruiz P, Tryggvason K, Shaw AS, Faul C, Sever S, Reiser J: CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival. J Clin Inv 2011;121:3965-3980
-
(2011)
J Clin Inv
, Issue.121
, pp. 3965-3980
-
-
Yaddanapudi, S.1
Altintas, M.M.2
Kistler, A.D.3
Fernandez, I.4
Möller, C.C.5
Wei, C.6
Peev, V.7
Flesche, J.B.8
Forst, A.-L.9
Li, J.10
Patrakka, J.11
Xiao, Z.12
Grahammer, F.13
Schiffer, M.14
Lohmüller, T.15
Reinheckel, T.16
Gu, C.17
Huber, T.B.18
Ju, W.19
Bitzer, M.20
Rastaldi, M.P.21
Ruiz, P.22
Tryggvason, K.23
Shaw, A.S.24
Faul, C.25
Sever, S.26
Reiser, J.27
more..
-
73
-
-
0038136885
-
CD2-Associated Protein Haploinsufficiency Is Linked to Glomerular Disease Susceptibility
-
Kim JM: CD2-Associated Protein Haploinsufficiency Is Linked to Glomerular Disease Susceptibility. Science 2003;300:1298-1300
-
(2003)
Science
, vol.300
, pp. 1298-1300
-
-
Kim, J.M.1
-
74
-
-
35848933493
-
Focal segmental glomerulosclerosis in a patient homozygous for a CD2AP mutation
-
Lowik MM, Groenen PJ, Pronk I, Lilien MR, Goldschmeding R, Dijkman HB, Levtchenko EN, Monnens LA, van den Heuvel LP: Focal segmental glomerulosclerosis in a patient homozygous for a CD2AP mutation. Kidney Int 2007;72:1198-1203
-
(2007)
Kidney Int
, vol.72
, pp. 1198-1203
-
-
Lowik, M.M.1
Groenen, P.J.2
Pronk, I.3
Lilien, M.R.4
Goldschmeding, R.5
Dijkman, H.B.6
Levtchenko, E.N.7
Monnens, L.A.8
Van Den Heuvel, L.P.9
-
75
-
-
67651091685
-
CD2AP mutations are associated with sporadic nephrotic syndrome and focal segmental glomerulosclerosis (FSGS)
-
Gigante M, Pontrelli P, Montemurno E, Roca L, Aucella F, Penza R, Caridi G, Ranieri E, Ghiggeri GM, Gesualdo L: CD2AP mutations are associated with sporadic nephrotic syndrome and focal segmental glomerulosclerosis (FSGS). Nephrol Dial Transplant 2009;24:1858-1864
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 1858-1864
-
-
Gigante, M.1
Pontrelli, P.2
Montemurno, E.3
Roca, L.4
Aucella, F.5
Penza, R.6
Caridi, G.7
Ranieri, E.8
Ghiggeri, G.M.9
Gesualdo, L.10
-
77
-
-
0033152045
-
Linkage of a gene causing familial focal segmental glomerulosclerosis to chromosome 11 and further evidence of genetic heterogeneity
-
Winn MP, Conlon PJ, Lynn KL, Howell DN, Slotterbeck BD, Smith AH, Graham FL, Bembe M, Quarles LD, Pericak-Vance MA, Vance JM: Linkage of a gene causing familial focal segmental glomerulosclerosis to chromosome 11 and further evidence of genetic heterogeneity. Genomics 1999;58:113-120
-
(1999)
Genomics
, vol.58
, pp. 113-120
-
-
Winn, M.P.1
Conlon, P.J.2
Lynn, K.L.3
Howell, D.N.4
Slotterbeck, B.D.5
Smith, A.H.6
Graham, F.L.7
Bembe, M.8
Quarles, L.D.9
Pericak-Vance, M.A.10
Vance, J.M.11
-
78
-
-
84861089120
-
Dexamethasone Resisted Podocyte Injury via Stabilizing TRPC6 Expression and Distribution
-
Yu S, Yu L: Dexamethasone Resisted Podocyte Injury via Stabilizing TRPC6 Expression and Distribution. Evid Based Complement Alternat Med 2012;2012:652059
-
(2012)
Evid Based Complement Alternat Med
, Issue.2012
, pp. 652059
-
-
Yu, S.1
Yu, L.2
-
79
-
-
34247197644
-
Galphaq-TRPC6-mediated Ca2+ entry induces RhoA activation and resultant endothelial cell shape change in response to thrombin
-
Singh I, Knezevic N, Ahmmed GU, Kini V, Malik AB, Mehta D: Galphaq-TRPC6-mediated Ca2+ entry induces RhoA activation and resultant endothelial cell shape change in response to thrombin. J Biol Chem 2007;282:7833-7843
-
(2007)
J Biol Chem
, vol.282
, pp. 7833-7843
-
-
Singh, I.1
Knezevic, N.2
Ahmmed, G.U.3
Kini, V.4
Malik, A.B.5
Mehta, D.6
-
80
-
-
78049524253
-
Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels
-
Tian D, Jacobo SM, Billing D, Rozkalne A, Gage SD, Anagnostou T, Pavenstadt H, Hsu HH, Schlondorff J, Ramos A, Greka A: Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels. Sci Signal 2010;3:ra77
-
(2010)
Sci Signal
, vol.3
-
-
Tian, D.1
Jacobo, S.M.2
Billing, D.3
Rozkalne, A.4
Gage, S.D.5
Anagnostou, T.6
Pavenstadt, H.7
Hsu, H.H.8
Schlondorff, J.9
Ramos, A.10
Greka, A.11
-
81
-
-
22844436647
-
TRPC6 is a glomerular slit diaphragm-Associated channel required for normal renal function
-
Reiser J, Polu KR, Moller CC, Kenlan P, Altintas MM, Wei C, Faul C, Herbert S, Villegas I, Avila-Casado C, McGee M, Sugimoto H, Brown D, Kalluri R, Mundel P, Smith PL, Clapham DE, Pollak MR: TRPC6 is a glomerular slit diaphragm-Associated channel required for normal renal function. Nat Genet 2005;37:739- 744
-
(2005)
Nat Genet
, vol.37
, pp. 739-744
-
-
Reiser, J.1
Polu, K.R.2
Moller, C.C.3
Kenlan, P.4
Altintas, M.M.5
Wei, C.6
Faul, C.7
Herbert, S.8
Villegas, I.9
Avila-Casado, C.10
McGee, M.11
Sugimoto, H.12
Brown, D.13
Kalluri, R.14
Mundel, P.15
Smith, P.L.16
Clapham, D.E.17
Pollak, M.R.18
-
82
-
-
33751225687
-
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
-
Huber TB, Schermer B, Muller RU, Hohne M, Bartram M, Calixto A, Hagmann H, Reinhardt C, Koos F, Kunzelmann K, Shirokova E, Krautwurst D, Harteneck C, Simons M, Pavenstadt H, Kerjaschki D, Thiele C, Walz G, Chalfie M, Benzing T: Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels. Proc Natl Acad Sci U S A 2006;103:17079-17086
-
(2006)
Proc Natl Acad Sci U S A
, Issue.103
, pp. 17079-17086
-
-
Huber, T.B.1
Schermer, B.2
Muller, R.U.3
Hohne, M.4
Bartram, M.5
Calixto, A.6
Hagmann, H.7
Reinhardt, C.8
Koos, F.9
Kunzelmann, K.10
Shirokova, E.11
Krautwurst, D.12
Harteneck, C.13
Simons, M.14
Pavenstadt, H.15
Kerjaschki, D.16
Thiele, C.17
Walz, G.18
Chalfie, M.19
Benzing, T.20
more..
-
83
-
-
0036171986
-
Calcineurin as a multifunctional regulator
-
Shibasaki F, Hallin U, Uchino H: Calcineurin as a multifunctional regulator. J Biochem 2002;131:1-15
-
(2002)
J Biochem
, vol.131
, pp. 1-15
-
-
Shibasaki, F.1
Hallin, U.2
Uchino, H.3
-
84
-
-
79960314279
-
TRPC6 mutations in children with steroid-resistant nephrotic syndrome and atypical phenotype
-
Gigante M, Caridi G, Montemurno E, Soccio M, d'Apolito M, Cerullo G, Aucella F, Schirinzi A, Emma F, Massella L, Messina G, De Palo T, Ranieri E, Ghiggeri GM, Gesualdo L: TRPC6 mutations in children with steroid-resistant nephrotic syndrome and atypical phenotype. Clin J Am Soc Nephrol 2011;6:1626-1634
-
(2011)
Clin J Am Soc Nephrol
, Issue.6
, pp. 1626-1634
-
-
Gigante, M.1
Caridi, G.2
Montemurno, E.3
Soccio, M.4
D'Apolito, M.5
Cerullo, G.6
Aucella, F.7
Schirinzi, A.8
Emma, F.9
Massella, L.10
Messina, G.11
De Palo, T.12
Ranieri, E.13
Ghiggeri, G.M.14
Gesualdo, L.15
-
85
-
-
70349498771
-
TRPC6 mutational analysis in a large cohort of patients with focal segmental glomerulosclerosis
-
Santin S, Ars E, Rossetti S, Salido E, Silva I, Garcia-Maset R, Gimenez I, Ruiz P, Mendizabal S, Luciano Nieto J, Pena A, Camacho JA, Fraga G, Cobo MA, Bernis C, Ortiz A, de Pablos AL, Sanchez-Moreno A, Pintos G, Mirapeix E, Fernandez-Llama P, Ballarin J, Torra R, Zamora I, Lopez-Hellin J, Madrid A, Ventura C, Vilalta R, Espinosa L, Garcia C, Melgosa M, Navarro M, Gimenez A, Cots JV, Alexandra S, Caramelo C, Egido J, San Jose MD, de la Cerda F, Sala P, Raspall F, Vila A, Daza AM, Vazquez M, Ecija JL, Espinosa M, Justa ML, Poveda R, Aparicio C, Rosell J, Muley R, Montenegro J, Gonzalez D, Hidalgo E, de Frutos DB, Trillo E, Gracia S, de los Rios FJ: TRPC6 mutational analysis in a large cohort of patients with focal segmental glomerulosclerosis. Nephrol Dial Transplant 2009;24:3089-3096
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 3089-3096
-
-
Santin, S.1
Ars, E.2
Rossetti, S.3
Salido, E.4
Silva, I.5
Garcia-Maset, R.6
Gimenez, I.7
Ruiz, P.8
Mendizabal, S.9
Luciano Nieto, J.10
Pena, A.11
Camacho, J.A.12
Fraga, G.13
Cobo, M.A.14
Bernis, C.15
Ortiz, A.16
De Pablos, A.L.17
Sanchez-Moreno, A.18
Pintos, G.19
Mirapeix, E.20
Fernandez-Llama, P.21
Ballarin, J.22
Torra, R.23
Zamora, I.24
Lopez-Hellin, J.25
Madrid, A.26
Ventura, C.27
Vilalta, R.28
Espinosa, L.29
Garcia, C.30
Melgosa, M.31
Navarro, M.32
Gimenez, A.33
Cots, J.V.34
Alexandra, S.35
Caramelo, C.36
Egido, J.37
San Jose, M.D.38
De La Cerda, F.39
Sala, P.40
Raspall, F.41
Vila, A.42
Daza, A.M.43
Vazquez, M.44
Ecija, J.L.45
Espinosa, M.46
Justa, M.L.47
Poveda, R.48
Aparicio, C.49
Rosell, J.50
Muley, R.51
Montenegro, J.52
Gonzalez, D.53
Hidalgo, E.54
De Frutos, D.B.55
Trillo, E.56
Gracia, S.57
De Los Rios, F.J.58
more..
-
86
-
-
84856656088
-
TRPC6 gene variants in Turkish children with steroid-resistant nephrotic syndrome
-
Mir S, Yavascan O, Berdeli A, Sozeri B: TRPC6 gene variants in Turkish children with steroid-resistant nephrotic syndrome. Nephrol Dial Transplant 2011;27:205-209
-
(2011)
Nephrol Dial Transplant
, Issue.27
, pp. 205-209
-
-
Mir, S.1
Yavascan, O.2
Berdeli, A.3
Sozeri, B.4
-
87
-
-
0033537768
-
Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD
-
Wang HG, Pathan N, Ethell IM, Krajewski S, Yamaguchi Y, Shibasaki F, McKeon F, Bobo T, Franke TF, Reed JC: Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD. Science 1999;284:339-343
-
(1999)
Science
, vol.284
, pp. 339-343
-
-
Wang, H.G.1
Pathan, N.2
Ethell, I.M.3
Krajewski, S.4
Yamaguchi, Y.5
Shibasaki, F.6
McKeon, F.7
Bobo, T.8
Franke, T.F.9
Reed, J.C.10
-
88
-
-
0035671315
-
Mechanism of action of the calcineurin inhibitors
-
Halloran PF: Mechanism of action of the calcineurin inhibitors. Transplant Proc 2001;33:3067-3069
-
(2001)
Transplant Proc
, vol.33
, pp. 3067-3069
-
-
Halloran, P.F.1
-
89
-
-
0037353142
-
Cyclosporine in the treatment of idiopathic focal segmental glomerulosclerosis
-
Cattran DC: Cyclosporine in the treatment of idiopathic focal segmental glomerulosclerosis. Semin Nephrol 2003;23:234-241
-
(2003)
Semin Nephrol
, vol.23
, pp. 234-241
-
-
Cattran, D.C.1
-
90
-
-
33751531864
-
Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible
-
Hinkes B, Wiggins RC, Gbadegesin R, Vlangos CN, Seelow D, Nurnberg G, Garg P, Verma R, Chaib H, Hoskins BE, Ashraf S, Becker C, Hennies HC, Goyal M, Wharram BL, Schachter AD, Mudumana S, Drummond I, Kerjaschki D, Waldherr R, Dietrich A, Ozaltin F, Bakkaloglu A, Cleper R, Basel-Vanagaite L, Pohl M, Griebel M, Tsygin AN, Soylu A, Muller D, Sorli CS, Bunney TD, Katan M, Liu J, Attanasio M, O'Toole J F, Hasselbacher K, Mucha B, Otto EA, Airik R, Kispert A, Kelley GG, Smrcka AV, Gudermann T, Holzman LB, Nurnberg P, Hildebrandt F: Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible. Nat Genet 2006;38:1397-1405
-
(2006)
Nat Genet
, vol.38
, pp. 1397-1405
-
-
Hinkes, B.1
Wiggins, R.C.2
Gbadegesin, R.3
Vlangos, C.N.4
Seelow, D.5
Nurnberg, G.6
Garg, P.7
Verma, R.8
Chaib, H.9
Hoskins, B.E.10
Ashraf, S.11
Becker, C.12
Hennies, H.C.13
Goyal, M.14
Wharram, B.L.15
Schachter, A.D.16
Mudumana, S.17
Drummond, I.18
Kerjaschki, D.19
Waldherr, R.20
Dietrich, A.21
Ozaltin, F.22
Bakkaloglu, A.23
Cleper, R.24
Basel-Vanagaite, L.25
Pohl, M.26
Griebel, M.27
Tsygin, A.N.28
Soylu, A.29
Muller, D.30
Sorli, C.S.31
Bunney, T.D.32
Katan, M.33
Liu, J.34
Attanasio, M.35
O'Toole J, F.36
Hasselbacher, K.37
Mucha, B.38
Otto, E.A.39
Airik, R.40
Kispert, A.41
Kelley, G.G.42
Smrcka, A.V.43
Gudermann, T.44
Holzman, L.B.45
Nurnberg, P.46
Hildebrandt, F.47
more..
-
91
-
-
2342514426
-
PLC-epsilon: A shared effector protein in Ras-Rho-, and G alpha beta gamma-mediated signaling
-
Wing MR, Bourdon DM, Harden TK: PLC-epsilon: A shared effector protein in Ras-, Rho-, and G alpha beta gamma-mediated signaling. Mol Interv 2003;3:273-280
-
(2003)
Mol Interv
, vol.3
, pp. 273-280
-
-
Wing, M.R.1
Bourdon, D.M.2
Harden, T.K.3
-
92
-
-
77956123797
-
Mutational analysis of the PLCE1 gene in steroid resistant nephrotic syndrome
-
Boyer O, Benoit G, Gribouval O, Nevo F, Pawtowski A, Bilge I, Bircan Z, Deschenes G, Guay-Woodford LM, Hall M, Macher MA, Soulami K, Stefanidis CJ, Weiss R, Loirat C, Gubler MC, Antignac C: Mutational analysis of the PLCE1 gene in steroid resistant nephrotic syndrome. J Med Genet 2010;47:445-452
-
(2010)
J Med Genet
, Issue.47
, pp. 445-452
-
-
Boyer, O.1
Benoit, G.2
Gribouval, O.3
Nevo, F.4
Pawtowski, A.5
Bilge, I.6
Bircan, Z.7
Deschenes, G.8
Guay-Woodford, L.M.9
Hall, M.10
Macher, M.A.11
Soulami, K.12
Stefanidis, C.J.13
Weiss, R.14
Loirat, C.15
Gubler, M.C.16
Antignac, C.17
-
93
-
-
24344491858
-
IQGAP1 is a scaffold for mitogen-Activated protein kinase signaling
-
Roy M, Li Z, Sacks DB: IQGAP1 is a scaffold for mitogen-Activated protein kinase signaling. Mol Cell Biol 2005;25:7940-7952
-
(2005)
Mol Cell Biol
, vol.25
, pp. 7940-7952
-
-
Roy, M.1
Li, Z.2
Sacks, D.B.3
-
94
-
-
8444221929
-
Human laminin beta2 deficiency causes congenital nephrosis with mesangial sclerosis and distinct eye abnormalities
-
Zenker M, Aigner T, Wendler O, Tralau T, Muntefering H, Fenski R, Pitz S, Schumacher V, Royer-Pokora B, Wuhl E, Cochat P, Bouvier R, Kraus C, Mark K, Madlon H, Dotsch J, Rascher W, Maruniak-Chudek I, Lennert T, Neumann LM, Reis A: Human laminin beta2 deficiency causes congenital nephrosis with mesangial sclerosis and distinct eye abnormalities. Hum Mol Genet 2004;13:2625-2632
-
(2004)
Hum Mol Genet
, vol.13
, pp. 2625-2632
-
-
Zenker, M.1
Aigner, T.2
Wendler, O.3
Tralau, T.4
Muntefering, H.5
Fenski, R.6
Pitz, S.7
Schumacher, V.8
Royer-Pokora, B.9
Wuhl, E.10
Cochat, P.11
Bouvier, R.12
Kraus, C.13
Mark, K.14
Madlon, H.15
Dotsch, J.16
Rascher, W.17
Maruniak-Chudek, I.18
Lennert, T.19
Neumann, L.M.20
Reis, A.21
more..
-
95
-
-
0021837975
-
A clinicopathologic study of forty-eight infants with nephrotic syndrome
-
Sibley RK, Mahan J, Mauer SM, Vernier RL: A clinicopathologic study of forty-eight infants with nephrotic syndrome. Kidney Int 1985;27:544-552
-
(1985)
Kidney Int
, vol.27
, pp. 544-552
-
-
Sibley, R.K.1
Mahan, J.2
Mauer, S.M.3
Vernier, R.L.4
-
96
-
-
42949101458
-
Mutations in PLCE1 are a major cause of isolated diffuse mesangial sclerosis (IDMS)
-
Gbadegesin R, Hinkes BG, Hoskins BE, Vlangos CN, Heeringa SF, Liu J, Loirat C, Ozaltin F, Hashmi S, Ulmer F, Cleper R, Ettenger R, Antignac C, Wiggins RC, Zenker M, Hildebrandt F: Mutations in PLCE1 are a major cause of isolated diffuse mesangial sclerosis (IDMS). Nephrol Dial Transplant 2007;23:1291-1297
-
(2007)
Nephrol Dial Transplant
, vol.23
, pp. 1291-1297
-
-
Gbadegesin, R.1
Hinkes, B.G.2
Hoskins, B.E.3
Vlangos, C.N.4
Heeringa, S.F.5
Liu, J.6
Loirat, C.7
Ozaltin, F.8
Hashmi, S.9
Ulmer, F.10
Cleper, R.11
Ettenger, R.12
Antignac, C.13
Wiggins, R.C.14
Zenker, M.15
Hildebrandt, F.16
-
97
-
-
58149094460
-
Exclusion of homozygous PLCE1 (NPHS3) mutations in 69 families with idiopathic and hereditary FSGS
-
Gbadegesin R, Bartkowiak B, Lavin PJ, Mukerji N, Wu G, Bowling B, Eckel J, Damodaran T, Winn MP: Exclusion of homozygous PLCE1 (NPHS3) mutations in 69 families with idiopathic and hereditary FSGS. Pediatr Nephrol 2008;24:281-285
-
(2008)
Pediatr Nephrol
, vol.24
, pp. 281-285
-
-
Gbadegesin, R.1
Bartkowiak, B.2
Lavin, P.J.3
Mukerji, N.4
Wu, G.5
Bowling, B.6
Eckel, J.7
Damodaran, T.8
Winn, M.P.9
-
98
-
-
84881641667
-
Myosin 1e is a component of the glomerular slit diaphragm complex that regulates actin reorganization during cell-cell contact formation in podocytes
-
Bi J, Chase SE, Pellenz CD, Kurihara H, Fanning AS, Krendel M: Myosin 1e is a component of the glomerular slit diaphragm complex that regulates actin reorganization during cell-cell contact formation in podocytes. Am J Physiol Renal Physiol 2013;305:532-544
-
(2013)
Am J Physiol Renal Physiol
, Issue.305
, pp. 532-544
-
-
Bi, J.1
Chase, S.E.2
Pellenz, C.D.3
Kurihara, H.4
Fanning, A.S.5
Krendel, M.6
-
99
-
-
58149510603
-
Disruption of Myosin 1e promotes podocyte injury
-
Krendel M, Kim SV, Willinger T, Wang T, Kashgarian M, Flavell RA, Mooseker MS: Disruption of Myosin 1e promotes podocyte injury. J Am Soc Nephrol 2009;20:86-94
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 86-94
-
-
Krendel, M.1
Kim, S.V.2
Willinger, T.3
Wang, T.4
Kashgarian, M.5
Flavell, R.A.6
Mooseker, M.S.7
-
100
-
-
84867121905
-
Podocyte-specific knockout of myosin 1e disrupts glomerular filtration
-
Chase SE, Encina CV, Stolzenburg LR, Tatum AH, Holzman LB, Krendel M: Podocyte-specific knockout of myosin 1e disrupts glomerular filtration. Am J Physiol Renal Physiol 2012;303:F1099-1106
-
(2012)
Am J Physiol Renal Physiol
, vol.303
-
-
Chase, S.E.1
Encina, C.V.2
Stolzenburg, L.R.3
Tatum, A.H.4
Holzman, L.B.5
Krendel, M.6
-
101
-
-
80052272947
-
Exome sequencing identified MYO1E and NEIL1 as candidate genes for human autosomal recessive steroid-resistant nephrotic syndrome
-
Sanna-Cherchi S, Burgess KE, Nees SN, Caridi G, Weng PL, Dagnino M, Bodria M, Carrea A, Allegretta MA, Kim HR, Perry BJ, Gigante M, Clark LN, Kisselev S, Cusi D, Gesualdo L, Allegri L, Scolari F, D'Agati V, Shapiro LS, Pecoraro C, Palomero T, Ghiggeri GM, Gharavi AG: Exome sequencing identified MYO1E and NEIL1 as candidate genes for human autosomal recessive steroid-resistant nephrotic syndrome. Kidney Int 2011;80:389-396
-
(2011)
Kidney Int
, Issue.80
, pp. 389-396
-
-
Sanna-Cherchi, S.1
Burgess, K.E.2
Nees, S.N.3
Caridi, G.4
Weng, P.L.5
Dagnino, M.6
Bodria, M.7
Carrea, A.8
Allegretta, M.A.9
Kim, H.R.10
Perry, B.J.11
Gigante, M.12
Clark, L.N.13
Kisselev, S.14
Cusi, D.15
Gesualdo, L.16
Allegri, L.17
Scolari, F.18
D'Agati, V.19
Shapiro, L.S.20
Pecoraro, C.21
Palomero, T.22
Ghiggeri, G.M.23
Gharavi, A.G.24
more..
-
102
-
-
79960877647
-
MYO1E mutations and childhood familial focal segmental glomerulosclerosis
-
Mele C, Iatropoulos P, Donadelli R, Calabria A, Maranta R, Cassis P, Buelli S, Tomasoni S, Piras R, Krendel M, Bettoni S, Morigi M, Delledonne M, Pecoraro C, Abbate I, Capobianchi MR, Hildebrandt F, Otto E, Schaefer F, Macciardi F, Ozaltin F, Emre S, Ibsirlioglu T, Benigni A, Remuzzi G, Noris M: MYO1E mutations and childhood familial focal segmental glomerulosclerosis. N Engl J Med 2011;365:295-306
-
(2011)
N Engl J Med
, Issue.365
, pp. 295-306
-
-
Mele, C.1
Iatropoulos, P.2
Donadelli, R.3
Calabria, A.4
Maranta, R.5
Cassis, P.6
Buelli, S.7
Tomasoni, S.8
Piras, R.9
Krendel, M.10
Bettoni, S.11
Morigi, M.12
Delledonne, M.13
Pecoraro, C.14
Abbate, I.15
Capobianchi, M.R.16
Hildebrandt, F.17
Otto, E.18
Schaefer, F.19
Macciardi, F.20
Ozaltin, F.21
Emre, S.22
Ibsirlioglu, T.23
Benigni, A.24
Remuzzi, G.25
Noris, M.26
more..
-
103
-
-
34248154652
-
Mechanism and function of formins in the control of actin assembly
-
Goode BL, Eck MJ: Mechanism and function of formins in the control of actin assembly. Annu Rev Biochem 2007;76:593-627
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 593-627
-
-
Goode, B.L.1
Eck, M.J.2
-
104
-
-
84878733723
-
Inverted formin 2 regulates actin dynamics by antagonizing Rho/diaphanous-related formin signaling
-
Sun H, Schlondorff J, Higgs HN, Pollak MR: Inverted formin 2 regulates actin dynamics by antagonizing Rho/diaphanous-related formin signaling. J Am Soc Nephrol 2013;24:917-929
-
(2013)
J Am Soc Nephrol
, Issue.24
, pp. 917-929
-
-
Sun, H.1
Schlondorff, J.2
Higgs, H.N.3
Pollak, M.R.4
-
106
-
-
84873411608
-
Mutations in the INF2 gene account for a significant proportion of familial but not sporadic focal and segmental glomerulosclerosis
-
Barua M, Brown EJ, Charoonratana VT, Genovese G, Sun H, Pollak MR: Mutations in the INF2 gene account for a significant proportion of familial but not sporadic focal and segmental glomerulosclerosis. Kidney Int 2013;83:316-322
-
(2013)
Kidney Int
, Issue.83
, pp. 316-322
-
-
Barua, M.1
Brown, E.J.2
Charoonratana, V.T.3
Genovese, G.4
Sun, H.5
Pollak, M.R.6
-
107
-
-
84855171766
-
INF2 mutations in Charcot-Marie-Tooth disease with glomerulopathy
-
Boyer O, Nevo F, Plaisier E, Funalot B, Gribouval O, Benoit G, Cong EH, Arrondel C, Tete MJ, Montjean R, Richard L, Karras A, Pouteil-Noble C, Balafrej L, Bonnardeaux A, Canaud G, Charasse C, Dantal J, Deschenes G, Deteix P, Dubourg O, Petiot P, Pouthier D, Leguern E, Guiochon-Mantel A, Broutin I, Gubler MC, Saunier S, Ronco P, Vallat JM, Alonso MA, Antignac C, Mollet G: INF2 mutations in Charcot-Marie-Tooth disease with glomerulopathy. N Engl J Med 2011;365:2377-2388
-
(2011)
N Engl J Med
, Issue.365
, pp. 2377-2388
-
-
Boyer, O.1
Nevo, F.2
Plaisier, E.3
Funalot, B.4
Gribouval, O.5
Benoit, G.6
Cong, E.H.7
Arrondel, C.8
Tete, M.J.9
Montjean, R.10
Richard, L.11
Karras, A.12
Pouteil-Noble, C.13
Balafrej, L.14
Bonnardeaux, A.15
Canaud, G.16
Charasse, C.17
Dantal, J.18
Deschenes, G.19
Deteix, P.20
Dubourg, O.21
Petiot, P.22
Pouthier, D.23
Leguern, E.24
Guiochon-Mantel, A.25
Broutin, I.26
Gubler, M.C.27
Saunier, S.28
Ronco, P.29
Vallat, J.M.30
Alonso, M.A.31
Antignac, C.32
Mollet, G.33
more..
-
108
-
-
84883896736
-
INF2 mutations in Charcot-Marie-Tooth disease complicated with focal segmental glomerulosclerosis
-
Toyota K, Ogino D, Hayashi M, Taki M, Saito K, Abe A, Hashimoto T, Umetsu K, Tsukaguchi H, Hayasaka K: INF2 mutations in Charcot-Marie-Tooth disease complicated with focal segmental glomerulosclerosis. J Peripher Nerv Syst 2013;18:97-98
-
(2013)
J Peripher Nerv Syst
, Issue.18
, pp. 97-98
-
-
Toyota, K.1
Ogino, D.2
Hayashi, M.3
Taki, M.4
Saito, K.5
Abe, A.6
Hashimoto, T.7
Umetsu, K.8
Tsukaguchi, H.9
Hayasaka, K.10
-
109
-
-
73349132341
-
Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis
-
Brown EJ, Schlondorff JS, Becker DJ, Tsukaguchi H, Tonna SJ, Uscinski AL, Higgs HN, Henderson JM, Pollak MR: Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis. Nat Genet 2010;42:72- 76
-
(2010)
Nat Genet
, Issue.42
, pp. 72-76
-
-
Brown, E.J.1
Schlondorff, J.S.2
Becker, D.J.3
Tsukaguchi, H.4
Tonna, S.J.5
Uscinski, A.L.6
Higgs, H.N.7
Henderson, J.M.8
Pollak, M.R.9
-
111
-
-
0017883401
-
Chromosomal imbalance in the Aniridia-Wilms' tumor association: 11p interstitial deletion
-
Riccardi VM, Sujansky E, Smith AC, Francke U: Chromosomal imbalance in the Aniridia-Wilms' tumor association: 11p interstitial deletion. Pediatrics 1978;61:604-610
-
(1978)
Pediatrics
, vol.61
, pp. 604-610
-
-
Riccardi, V.M.1
Sujansky, E.2
Smith, A.C.3
Francke, U.4
-
112
-
-
0025288793
-
An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor
-
Haber DA, Buckler AJ, Glaser T, Call KM, Pelletier J, Sohn RL, Douglass EC, Housman DE: An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor. Cell 1990;61:1257- 1269
-
(1990)
Cell
, vol.61
, pp. 1257-1269
-
-
Haber, D.A.1
Buckler, A.J.2
Glaser, T.3
Call, K.M.4
Pelletier, J.5
Sohn, R.L.6
Douglass, E.C.7
Housman, D.E.8
-
114
-
-
1642514813
-
Development of an siRNAbased method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation
-
Davies JA, Ladomery M, Hohenstein P, Michael L, Shafe A, Spraggon L, Hastie N: Development of an siRNAbased method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation. Hum Mol Genet 2004;13:235-246
-
(2004)
Hum Mol Genet
, vol.13
, pp. 235-246
-
-
Davies, J.A.1
Ladomery, M.2
Hohenstein, P.3
Michael, L.4
Shafe, A.5
Spraggon, L.6
Hastie, N.7
-
115
-
-
82655189962
-
The podocyte as a target: Cyclosporin A in the management of the nephrotic syndrome caused by WT1 mutations
-
Stefanidis CJ, Querfeld U: The podocyte as a target: Cyclosporin A in the management of the nephrotic syndrome caused by WT1 mutations. Eur J Pediatr 2011;170:1377-1383
-
(2011)
Eur J Pediatr
, Issue.170
, pp. 1377-1383
-
-
Stefanidis, C.J.1
Querfeld, U.2
-
116
-
-
33745165056
-
Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway
-
Ito K, Oji Y, Tatsumi N, Shimizu S, Kanai Y, Nakazawa T, Asada M, Jomgeow T, Aoyagi S, Nakano Y, Tamaki H, Sakaguchi N, Shirakata T, Nishida S, Kawakami M, Tsuboi A, Oka Y, Tsujimoto Y, Sugiyama H: Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway. Oncogene 2006;25:4217-4229
-
(2006)
Oncogene
, vol.25
, pp. 4217-4229
-
-
Ito, K.1
Oji, Y.2
Tatsumi, N.3
Shimizu, S.4
Kanai, Y.5
Nakazawa, T.6
Asada, M.7
Jomgeow, T.8
Aoyagi, S.9
Nakano, Y.10
Tamaki, H.11
Sakaguchi, N.12
Shirakata, T.13
Nishida, S.14
Kawakami, M.15
Tsuboi, A.16
Oka, Y.17
Tsujimoto, Y.18
Sugiyama, H.19
-
117
-
-
13044266382
-
A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys-Drash syndrome
-
Patek CE, Little MH, Fleming S, Miles C, Charlieu JP, Clarke AR, Miyagawa K, Christie S, Doig J, Harrison DJ, Porteous DJ, Brookes AJ, Hooper ML, Hastie ND: A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys-Drash syndrome. Proc Natl Acad Sci U S A 1999;96:2931- 2936
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 2931-2936
-
-
Patek, C.E.1
Little, M.H.2
Fleming, S.3
Miles, C.4
Charlieu, J.P.5
Clarke, A.R.6
Miyagawa, K.7
Christie, S.8
Doig, J.9
Harrison, D.J.10
Porteous, D.J.11
Brookes, A.J.12
Hooper, M.L.13
Hastie, N.D.14
-
118
-
-
9644281578
-
The major podocyte protein nephrin is transcriptionally activated by the Wilms' tumor suppressor WT1
-
Wagner N, Wagner KD, Xing Y, Scholz H, Schedl A: The major podocyte protein nephrin is transcriptionally activated by the Wilms' tumor suppressor WT1. J Am Soc Nephrol 2004;15:3044-3051
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 3044-3051
-
-
Wagner, N.1
Wagner, K.D.2
Xing, Y.3
Scholz, H.4
Schedl, A.5
-
119
-
-
0037087593
-
WT1 is a key regulator of podocyte function: Reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis
-
Guo JK, Menke AL, Gubler MC, Clarke AR, Harrison D, Hammes A, Hastie ND, Schedl A: WT1 is a key regulator of podocyte function: Reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis. Hum Mol Genet 2002;11:651-659
-
(2002)
Hum Mol Genet
, vol.11
, pp. 651-659
-
-
Guo, J.K.1
Menke, A.L.2
Gubler, M.C.3
Clarke, A.R.4
Harrison, D.5
Hammes, A.6
Hastie, N.D.7
Schedl, A.8
-
120
-
-
17344364993
-
Identification of constitutional WT1 mutations, in patients with isolated diffuse mesangial sclerosis, and analysis of genotype/phenotype correlations by use of a computerized mutation database
-
Jeanpierre C, Denamur E, Henry I, Cabanis MO, Luce S, Cecille A, Elion J, Peuchmaur M, Loirat C, Niaudet P, Gubler MC, Junien C: Identification of constitutional WT1 mutations, in patients with isolated diffuse mesangial sclerosis, and analysis of genotype/phenotype correlations by use of a computerized mutation database. Am J Hum Genet 1998;62:824-833
-
(1998)
Am J Hum Genet
, vol.62
, pp. 824-833
-
-
Jeanpierre, C.1
Denamur, E.2
Henry, I.3
Cabanis, M.O.4
Luce, S.5
Cecille, A.6
Elion, J.7
Peuchmaur, M.8
Loirat, C.9
Niaudet, P.10
Gubler, M.C.11
Junien, C.12
-
121
-
-
0023477994
-
Chronic Renal Failure And XY Gonadal Dysgenesis "Frasier" syndrome-A commentary on reported cases
-
Moorthy AV, Chesney RW, Lubinsky M: Chronic renal failure and XY gonadal dysgenesis: "Frasier" syndrome-A commentary on reported cases. Am J Med Genet Suppl 1987;3:297-302
-
(1987)
Am J Med Genet Suppl
, vol.3
, pp. 297-302
-
-
Moorthy, A.V.1
Chesney, R.W.2
Lubinsky, M.3
-
122
-
-
0033624770
-
WT1 splice-site mutations are rarely associated with primary steroid-resistant focal and segmental glomerulosclerosis
-
Denamur E, Bocquet N, Baudouin V, Da Silva F, Veitia R, Peuchmaur M, Elion J, Gubler MC, Fellous M, Niaudet P, Loirat C: WT1 splice-site mutations are rarely associated with primary steroid-resistant focal and segmental glomerulosclerosis. Kidney Int 2000;57:1868-1872
-
(2000)
Kidney Int
, vol.57
, pp. 1868-1872
-
-
Denamur, E.1
Bocquet, N.2
Baudouin, V.3
Da Silva, F.4
Veitia, R.5
Peuchmaur, M.6
Elion, J.7
Gubler, M.C.8
Fellous, M.9
Niaudet, P.10
Loirat, C.11
-
123
-
-
70350656203
-
Kidney disease in nail-patella syndrome
-
Lemley KV: Kidney disease in nail-patella syndrome. Pediatr Nephrol 2008;24:2345-2354
-
(2008)
Pediatr Nephrol
, vol.24
, pp. 2345-2354
-
-
Lemley, K.V.1
-
124
-
-
0031800728
-
Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome
-
Dreyer SD, Zhou G, Baldini A, Winterpacht A, Zabel B, Cole W, Johnson RL, Lee B: Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome. Nat Genet 1998;19:47-50
-
(1998)
Nat Genet
, vol.19
, pp. 47-50
-
-
Dreyer, S.D.1
Zhou, G.2
Baldini, A.3
Winterpacht, A.4
Zabel, B.5
Cole, W.6
Johnson, R.L.7
Lee, B.8
-
125
-
-
0031750061
-
Loss-of-function mutations in the LIM-homeodomain gene, LMX1B, in nail-patella syndrome
-
Vollrath D, Jaramillo-Babb VL, Clough MV, McIntosh I, Scott KM, Lichter PR, Richards JE: Loss-of-function mutations in the LIM-homeodomain gene, LMX1B, in nail-patella syndrome. Hum Mol Genet 1998;7:1091- 1098
-
(1998)
Hum Mol Genet
, vol.7
, pp. 1091-1098
-
-
Vollrath, D.1
Jaramillo-Babb, V.L.2
Clough, M.V.3
McIntosh, I.4
Scott, K.M.5
Lichter, P.R.6
Richards, J.E.7
-
126
-
-
0036117988
-
The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes
-
Rohr C: The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes. J Clin Invest 2002;109:1073-1082
-
(2002)
J Clin Invest
, vol.109
, pp. 1073-1082
-
-
Rohr, C.1
-
127
-
-
70349914303
-
The transcriptional regulation of podocin (NPHS2) by Lmx1b and a promoter single nucleotide polymorphism
-
Harendza S, Stahl RA, Schneider A: The transcriptional regulation of podocin (NPHS2) by Lmx1b and a promoter single nucleotide polymorphism. Cell Mol Biol Lett 2009;14:679-691
-
(2009)
Cell Mol Biol Lett
, vol.14
, pp. 679-691
-
-
Harendza, S.1
Stahl, R.A.2
Schneider, A.3
-
128
-
-
23644447910
-
Genotype-phenotype studies in nail-patella syndrome show that LMX1B mutation location is involved in the risk of developing nephropathy
-
Bongers EMHF, Huysmans FT, Levtchenko E, de Rooy JW, Blickman JG, Admiraal RJC, Huygen PLM, Cruysberg JRM, Toolens PAMP, Prins JB, Krabbe PFM, Borm GF, Schoots J, van Bokhoven H, van Remortele AMF, Hoefsloot LH, van Kampen A, Knoers NVAM: Genotype-phenotype studies in nail-patella syndrome show that LMX1B mutation location is involved in the risk of developing nephropathy. Eur J Hum Genet 2005;13:935-946
-
(2005)
Eur J Hum Genet
, vol.13
, pp. 935-946
-
-
Bongers, E.M.H.F.1
Huysmans, F.T.2
Levtchenko, E.3
De Rooy, J.W.4
Blickman, J.G.5
Admiraal, R.J.C.6
Huygen, P.L.M.7
Cruysberg Jr., M.8
Toolens, P.A.M.P.9
Prins, J.B.10
Krabbe, P.F.M.11
Borm, G.F.12
Schoots, J.13
Van Bokhoven, H.14
Van Remortele, A.M.F.15
Hoefsloot, L.H.16
Van Kampen, A.17
Knoers, N.V.A.M.18
-
129
-
-
77956293608
-
Mutations in the human laminin β2 (LAMB2) gene and the associated phenotypic spectruma
-
Matejas V, Hinkes B, Alkandari F, Al-Gazali L, Annexstad E, Aytac MB, Barrow M, Bláhová K, Bockenhauer D, Cheong HI, Maruniak-Chudek I, Cochat P, Dötsch J, Gajjar P, Hennekam RC, Janssen F, Kagan M, Kariminejad A, Kemper MJ, Koenig J, Kogan J, Kroes HY, Kuwertz-Bröking E, Lewanda AF, Medeira A, Muscheites J, Niaudet P, Pierson M, Saggar A, Seaver L, Suri M, Tsygin A, Wühl E, Zurowska A, Uebe S, Hildebrandt F, Antignac C, Zenker M: Mutations in the human laminin β2 (LAMB2) gene and the associated phenotypic spectruma. Hum Mutat 2010;31:992-1002
-
(2010)
Hum Mutat
, Issue.31
, pp. 992-1002
-
-
Matejas, V.1
Hinkes, B.2
Alkandari, F.3
Al-Gazali, L.4
Annexstad, E.5
Aytac, M.B.6
Barrow, M.7
Bláhová, K.8
Bockenhauer, D.9
Cheong, H.I.10
Maruniak-Chudek, I.11
Cochat, P.12
Dötsch, J.13
Gajjar, P.14
Hennekam, R.C.15
Janssen, F.16
Kagan, M.17
Kariminejad, A.18
Kemper, M.J.19
Koenig, J.20
Kogan, J.21
Kroes, H.Y.22
Kuwertz-Bröking, E.23
Lewanda, A.F.24
Medeira, A.25
Muscheites, J.26
Niaudet, P.27
Pierson, M.28
Saggar, A.29
Seaver, L.30
Suri, M.31
Tsygin, A.32
Wühl, E.33
Zurowska, A.34
Uebe, S.35
Hildebrandt, F.36
Antignac, C.37
Zenker, M.38
more..
-
131
-
-
0033460287
-
Renal basement membrane components
-
Miner JH: Renal basement membrane components. Kidney Int 1999;56:2016-2024
-
(1999)
Kidney Int
, vol.56
, pp. 2016-2024
-
-
Miner, J.H.1
-
132
-
-
0030919488
-
The laminin alpha chains: Expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform
-
Miner JH, Patton BL, Lentz SI, Gilbert DJ, Snider WD, Jenkins NA, Copeland NG, Sanes JR: The laminin alpha chains: Expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform. J Cell Biol 1997;137:685-701
-
(1997)
J Cell Biol
, vol.137
, pp. 685-701
-
-
Miner, J.H.1
Patton, B.L.2
Lentz, S.I.3
Gilbert, D.J.4
Snider, W.D.5
Jenkins, N.A.6
Copeland, N.G.7
Sanes, J.R.8
-
133
-
-
0028171098
-
Collagen IV alpha 3, alpha 4, and alpha 5 chains in rodent basal laminae: Sequence, distribution, association with laminins, and developmental switches
-
Miner JH, Sanes JR: Collagen IV alpha 3, alpha 4, and alpha 5 chains in rodent basal laminae: Sequence, distribution, association with laminins, and developmental switches. J Cell Biol 1994;127:879-891
-
(1994)
J Cell Biol
, vol.127
, pp. 879-891
-
-
Miner, J.H.1
Sanes, J.R.2
-
134
-
-
24344440893
-
Building the glomerulus: A matricentric view
-
Miner JH: Building the glomerulus: A matricentric view. J Am Soc Nephrol 2005;16:857-861
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 857-861
-
-
Miner, J.H.1
-
135
-
-
34547093441
-
Role of laminin terminal globular domains in basement membrane assembly
-
McKee KK, Harrison D, Capizzi S, Yurchenco PD: Role of laminin terminal globular domains in basement membrane assembly. J Biol Chem 2007;282:21437-21447
-
(2007)
J Biol Chem
, vol.282
, pp. 21437-21447
-
-
McKee, K.K.1
Harrison, D.2
Capizzi, S.3
Yurchenco, P.D.4
-
136
-
-
4744349621
-
An Unusual Congenital And Familial Congenital Malformative Combination Involving The Eye And Kidney
-
Pierson M, Cordier J, Hervouuet F, Rauber G: [an Unusual Congenital and Familial Congenital Malformative Combination Involving the Eye and Kidney]. J Genet Hum 1963;12:184-213
-
(1963)
J Genet Hum
, vol.12
, pp. 184-213
-
-
Pierson, M.1
Cordier, J.2
Hervouuet, F.3
Rauber, G.4
-
137
-
-
79955640326
-
A Missense LAMB2 Mutation Causes Congenital Nephrotic Syndrome by Impairing Laminin Secretion
-
Chen YM, Kikkawa Y, Miner JH: A Missense LAMB2 Mutation Causes Congenital Nephrotic Syndrome by Impairing Laminin Secretion. J Am Soc Nephrol 2011;22:849-858
-
(2011)
J Am Soc Nephrol
, Issue.22
, pp. 849-858
-
-
Chen, Y.M.1
Kikkawa, Y.2
Miner, J.H.3
-
138
-
-
34548145333
-
Utility of genetic screening in children with nephrotic syndrome presenting during the first year of life
-
Niaudet P: Utility of genetic screening in children with nephrotic syndrome presenting during the first year of life. Nat Clin Pract Nephrol 2007;3:472-473
-
(2007)
Nat Clin Pract Nephrol
, vol.3
, pp. 472-473
-
-
Niaudet, P.1
-
139
-
-
84876040962
-
Simultaneous sequencing of 24 genes associated with steroid-resistant nephrotic syndrome
-
McCarthy HJ, Bierzynska A, Wherlock M, Ognjanovic M, Kerecuk L, Hegde S, Feather S, Gilbert RD, Krischock L, Jones C, Sinha MD, Webb NJ, Christian M, Williams MM, Marks S, Koziell A, Welsh GI, Saleem MA: Simultaneous sequencing of 24 genes associated with steroid-resistant nephrotic syndrome. Clin J Am Soc Nephrol 2013;8:637-648
-
(2013)
Clin J Am Soc Nephrol
, Issue.8
, pp. 637-648
-
-
McCarthy, H.J.1
Bierzynska, A.2
Wherlock, M.3
Ognjanovic, M.4
Kerecuk, L.5
Hegde, S.6
Feather, S.7
Gilbert, R.D.8
Krischock, L.9
Jones, C.10
Sinha, M.D.11
Webb, N.J.12
Christian, M.13
Williams, M.M.14
Marks, S.15
Koziell, A.16
Welsh, G.I.17
Saleem, M.A.18
-
141
-
-
34147096001
-
Nephrotic syndrome in the first year of life: Two thirds of cases are caused by mutations in 4 genes (NPHS1, NPHS2, WT1, and LAMB2)
-
Hinkes BG, Mucha B, Vlangos CN, Gbadegesin R, Liu J, Hasselbacher K, Hangan D, Ozaltin F, Zenker M, Hildebrandt F: Nephrotic syndrome in the first year of life: Two thirds of cases are caused by mutations in 4 genes (NPHS1, NPHS2, WT1, and LAMB2). Pediatrics 2007;119:e907-919
-
(2007)
Pediatrics
, vol.119
-
-
Hinkes, B.G.1
Mucha, B.2
Vlangos, C.N.3
Gbadegesin, R.4
Liu, J.5
Hasselbacher, K.6
Hangan, D.7
Ozaltin, F.8
Zenker, M.9
Hildebrandt, F.10
-
142
-
-
84881312661
-
Genetics of steroid-resistant nephrotic syndrome: A review of mutation spectrum and suggested approach for genetic testing
-
Joshi S, Andersen R, Jespersen B, Rittig S: Genetics of steroid-resistant nephrotic syndrome: A review of mutation spectrum and suggested approach for genetic testing. Acta Paediatr 2013;102:844-856
-
(2013)
Acta Paediatr
, Issue.102
, pp. 844-856
-
-
Joshi, S.1
Andersen, R.2
Jespersen, B.3
Rittig, S.4
-
143
-
-
0030615201
-
Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
-
Barnes PJ, Karin M: Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 1997;336:1066-1071
-
(1997)
N Engl J Med
, vol.336
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
144
-
-
8344233333
-
Mechanisms of glucocorticoid receptor signaling during inflammation
-
Smoak KA, Cidlowski JA: Mechanisms of glucocorticoid receptor signaling during inflammation. Mech Ageing Dev 2004;125:697-706
-
(2004)
Mech Ageing Dev
, vol.125
, pp. 697-706
-
-
Smoak, K.A.1
Cidlowski, J.A.2
-
145
-
-
1642326111
-
Enhancement of MEK/ERK signaling promotes glucocorticoid resistance in CD4+ T cells
-
Tsitoura DC: Enhancement of MEK/ERK signaling promotes glucocorticoid resistance in CD4+ T cells. J Clin Invest 2004;113:619-627
-
(2004)
J Clin Invest
, vol.113
, pp. 619-627
-
-
Tsitoura, D.C.1
-
146
-
-
79959911826
-
Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding
-
Biddie SC, John S, Sabo PJ, Thurman RE, Johnson TA, Schiltz RL, Miranda TB, Sung MH, Trump S, Lightman SL, Vinson C, Stamatoyannopoulos JA, Hager GL: Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding. Mol Cell 2011;43:145-155
-
(2011)
Mol Cell
, Issue.43
, pp. 145-155
-
-
Biddie, S.C.1
John, S.2
Sabo, P.J.3
Thurman, R.E.4
Johnson, T.A.5
Schiltz, R.L.6
Miranda, T.B.7
Sung, M.H.8
Trump, S.9
Lightman, S.L.10
Vinson, C.11
Stamatoyannopoulos, J.A.12
Hager, G.L.13
-
148
-
-
0030479056
-
Ten years later: What have we learned about human aging from studies of cell cultures?
-
Cristofalo VJ: Ten years later: What have we learned about human aging from studies of cell cultures? Gerontologist 1996;36:737-741
-
(1996)
Gerontologist
, vol.36
, pp. 737-741
-
-
Cristofalo, V.J.1
-
149
-
-
0028174061
-
Function and activation of NF-kappa B in the immune system
-
Baeuerle PA, Henkel T: Function and activation of NF-kappa B in the immune system. Annu Rev Immunol 1994;12:141-179
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 141-179
-
-
Baeuerle, P.A.1
Henkel, T.2
-
150
-
-
77649242814
-
A new link between steroid resistance, glucocorticoid receptor and nuclear factor kappa B p65 in idiopathic nephrotic syndrome
-
Szilagyi K, Podracka L, Franke NE, Mojzis J, Mirossay L: A new link between steroid resistance, glucocorticoid receptor and nuclear factor kappa B p65 in idiopathic nephrotic syndrome. Neuro Endocrinol Lett 2009;30:629-636
-
(2009)
Neuro Endocrinol Lett
, vol.30
, pp. 629-636
-
-
Szilagyi, K.1
Podracka, L.2
Franke, N.E.3
Mojzis, J.4
Mirossay, L.5
-
151
-
-
0031916865
-
Cross-Talk between nuclear factor-kB and the steroid hormone receptors; mechanism of mutual antagonism
-
MCKAY LI CJ: Cross-Talk between nuclear factor-kB and the steroid hormone receptors; mechanism of mutual antagonism. Mol Endo 1998;12:45-56
-
(1998)
Mol Endo
, vol.12
, pp. 45-56
-
-
Mckay Li, C.J.1
-
152
-
-
3042845734
-
Decreased expression of T-cell NF-kappaB p65 subunit in steroid-resistant nephrotic syndrome
-
Aviles DH, Matti Vehaskari V, Manning J, Ochoa AC, Zea AH: Decreased expression of T-cell NF-kappaB p65 subunit in steroid-resistant nephrotic syndrome. Kidney Int 2004;66:60-67
-
(2004)
Kidney Int
, vol.66
, pp. 60-67
-
-
Aviles, D.H.1
Matti Vehaskari, V.2
Manning, J.3
Ochoa, A.C.4
Zea, A.H.5
-
153
-
-
0019971851
-
T-cell dysfunction in minimal-change nephrotic syndrome of childhood
-
Fodor P, Saitua MT, Rodriguez E, Gonzalez B, Schlesinger L: T-cell dysfunction in minimal-change nephrotic syndrome of childhood. Am J Dis Child 1982;136:713-717
-
(1982)
Am J Dis Child
, vol.136
, pp. 713-717
-
-
Fodor, P.1
Saitua, M.T.2
Rodriguez, E.3
Gonzalez, B.4
Schlesinger, L.5
-
154
-
-
0033810192
-
Glomerular endothelial dysfunction and altered cytokines in severe nephrosis
-
Futrakul N, Butthep P, Patumraj S, Futrakul P: Glomerular endothelial dysfunction and altered cytokines in severe nephrosis. Nephron 2000;86:199
-
(2000)
Nephron
, vol.86
, pp. 199
-
-
Futrakul, N.1
Butthep, P.2
Patumraj, S.3
Futrakul, P.4
-
155
-
-
0030918249
-
T-lymphocyte populations, cytokines and other growth factors in serum and urine of children with idiopathic nephrotic syndrome
-
Daniel V, Trautmann Y, Konrad M, Nayir A, Scharer K: T-lymphocyte populations, cytokines and other growth factors in serum and urine of children with idiopathic nephrotic syndrome. Clin Nephrol 1997;47:289-297
-
(1997)
Clin Nephrol
, vol.47
, pp. 289-297
-
-
Daniel, V.1
Trautmann, Y.2
Konrad, M.3
Nayir, A.4
Scharer, K.5
-
156
-
-
1642480086
-
Glucocorticoid receptors, in vitro steroid sensitivity, and cytokine secretion in idiopathic nephrotic syndrome
-
Carlotti AP, Franco PB, Elias LL, Facincani I, Costa EL, Foss N, Moreira AC, de Castro M: Glucocorticoid receptors, in vitro steroid sensitivity, and cytokine secretion in idiopathic nephrotic syndrome. Kidney Int 2004;65:403-408
-
(2004)
Kidney Int
, vol.65
, pp. 403-408
-
-
Carlotti, A.P.1
Franco, P.B.2
Elias, L.L.3
Facincani, I.4
Costa, E.L.5
Foss, N.6
Moreira, A.C.7
De Castro, M.8
-
157
-
-
0033052190
-
Th1 and Th2 cytokine mRNA profiles in childhood nephrotic syndrome: Evidence for increased IL-13 mRNA expression in relapse
-
Yap HK, Cheung W, Murugasu B, Sim SK, Seah CC, Jordan SC: Th1 and Th2 cytokine mRNA profiles in childhood nephrotic syndrome: Evidence for increased IL-13 mRNA expression in relapse. J Am Soc Nephrol 1999;10:529-537
-
(1999)
J Am Soc Nephrol
, vol.10
, pp. 529-537
-
-
Yap, H.K.1
Cheung, W.2
Murugasu, B.3
Sim, S.K.4
Seah, C.C.5
Jordan, S.C.6
-
158
-
-
0034838932
-
Th2 predominance at the single-cell level in patients with IgA nephropathy
-
Ebihara I, Hirayama K, Yamamoto S, Muro K, Yamagata K, Koyama A: Th2 predominance at the single-cell level in patients with IgA nephropathy. Nephrol Dial Transplant 2001;16:1783-1789
-
(2001)
Nephrol Dial Transplant
, vol.16
, pp. 1783-1789
-
-
Ebihara, I.1
Hirayama, K.2
Yamamoto, S.3
Muro, K.4
Yamagata, K.5
Koyama, A.6
-
159
-
-
70350011932
-
Idiopathic nephrotic syndrome and atopy is there a common link?
-
Abdel-Hafez M, Shimada M, Lee PY, Johnson RJ, Garin EH: Idiopathic nephrotic syndrome and atopy: Is there a common link? Am J Kidney Dis 2009;54:945-953
-
(2009)
Am J Kidney Dis
, vol.54
, pp. 945-953
-
-
Abdel-Hafez, M.1
Shimada, M.2
Lee, P.Y.3
Johnson, R.J.4
Garin, E.H.5
-
160
-
-
84863087151
-
The Clinical Characteristics of Steroid Responsive Nephrotic Syndrome of Children according to the Serum Immunoglobulin E Levels and Cytokines
-
Youn YS, Lim HH, Lee JH: The Clinical Characteristics of Steroid Responsive Nephrotic Syndrome of Children according to the Serum Immunoglobulin E Levels and Cytokines. Yonsei Med J 2012;53:715
-
(2012)
Yonsei Med J
, vol.53
, pp. 715
-
-
Youn, Y.S.1
Lim, H.H.2
Lee, J.H.3
|