-
1
-
-
0029037126
-
The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation
-
7715646 10.1056/NEJM199505183322008
-
GP Chrousos 1995 The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation N Engl J Med 332 1351 1362 7715646 10.1056/NEJM199505183322008
-
(1995)
N Engl J Med
, vol.332
, pp. 1351-1362
-
-
Chrousos, G.P.1
-
2
-
-
0034965716
-
Glucocorticoid and mineralocorticoid resistance/hypersensitivity syndromes
-
DOI 10.1677/joe.0.1690437
-
T Kino GP Chrousos 2001 Glucocorticoid and mineralocorticoid resistance/hypersensitivity syndromes J Endocrinol 169 437 445 11375113 10.1677/joe.0.1690437 (Pubitemid 32536976)
-
(2001)
Journal of Endocrinology
, vol.169
, Issue.3
, pp. 437-445
-
-
Kino, T.1
Chrousos, G.P.2
-
3
-
-
77956681311
-
Glucocorticoid effect on gene expression
-
T. Steckler N.H. Kalin JMHM Reul (eds). Elsevier Amsterdam
-
Kino T, Chrousos GP (2005) Glucocorticoid effect on gene expression. In: Steckler T, Kalin NH, Reul JMHM (eds) Handbook on stress and the brain. Elsevier, Amsterdam, pp 295-312
-
(2005)
Handbook on Stress and the Brain
, pp. 295-312
-
-
Kino, T.1
Chrousos, G.P.2
-
4
-
-
1442272396
-
Glucocorticoid therapy
-
P. Felig L.A. Frohman (eds). McGraw-Hill New York
-
Chrousos GP (2001) Glucocorticoid therapy. In: Felig P, Frohman LA (eds) Endocrinology and metabolism. McGraw-Hill, New York, pp 609-632
-
(2001)
Endocrinology and Metabolism
, pp. 609-632
-
-
Chrousos, G.P.1
-
5
-
-
33644875471
-
Intracellular glucocorticoid signaling: A formerly simple system turns stochastic
-
Chrousos GP, Kino T (2005) Intracellular glucocorticoid signaling: a formerly simple system turns stochastic. Sci STKE 2005, pe48
-
(2005)
Sci STKE 2005
, pp. 48
-
-
Chrousos, G.P.1
Kino, T.2
-
6
-
-
3142520021
-
Glucocorticoid and mineralocorticoid receptors and associated diseases
-
15242344
-
T Kino GP Chrousos 2004 Glucocorticoid and mineralocorticoid receptors and associated diseases Essays Biochem 40 137 155 15242344
-
(2004)
Essays Biochem
, vol.40
, pp. 137-155
-
-
Kino, T.1
Chrousos, G.P.2
-
8
-
-
0029056558
-
Glucocorticoid receptor β, a potential endogenous inhibitor of glucocorticoid action in humans
-
7769088 10.1172/JCI117943
-
CM Bamberger AM Bamberger M de Castro GP Chrousos 1995 Glucocorticoid receptor β, a potential endogenous inhibitor of glucocorticoid action in humans J Clin Invest 95 2435 2441 7769088 10.1172/JCI117943
-
(1995)
J Clin Invest
, vol.95
, pp. 2435-2441
-
-
Bamberger, C.M.1
Bamberger, A.M.2
De Castro, M.3
Chrousos, G.P.4
-
9
-
-
0029807036
-
The non-ligand binding β-isoform of the human glucocorticoid receptor (hGRβ): Tissue levels, mechanism of action, and potential physiologic role
-
8898375
-
M de Castro S Elliot T Kino C Bamberger M Karl E Webster GP Chrousos 1996 The non-ligand binding β-isoform of the human glucocorticoid receptor (hGRβ): tissue levels, mechanism of action, and potential physiologic role Mol Med 2 597 607 8898375
-
(1996)
Mol Med
, vol.2
, pp. 597-607
-
-
De Castro, M.1
Elliot, S.2
Kino, T.3
Bamberger, C.4
Karl, M.5
Webster, E.6
Chrousos, G.P.7
-
10
-
-
62949138967
-
Glucocorticoid receptor (GR) β has intrinsic, GRα-independent transcriptional activity
-
19248771 10.1016/j.bbrc.2009.02.110
-
T Kino I Manoli S Kelkar Y Wang YA Su GP Chrousos 2009 Glucocorticoid receptor (GR) β has intrinsic, GRα-independent transcriptional activity Biochem Biophys Res Commun 381 671 675 19248771 10.1016/j.bbrc.2009.02. 110
-
(2009)
Biochem Biophys Res Commun
, vol.381
, pp. 671-675
-
-
Kino, T.1
Manoli, I.2
Kelkar, S.3
Wang, Y.4
Su, Y.A.5
Chrousos, G.P.6
-
13
-
-
0034909433
-
Multiple promoters exist in the human GR gene, one of which is activated by glucocorticoids
-
DOI 10.1210/me.15.8.1381
-
MB Breslin CD Geng WV Vedeckis 2001 Multiple promoters exist in the human GR gene, one of which is activated by glucocorticoids Mol Endocrinol 15 1381 1395 11463861 10.1210/me.15.8.1381 (Pubitemid 32703485)
-
(2001)
Molecular Endocrinology
, vol.15
, Issue.8
, pp. 1381-1395
-
-
Breslin, M.B.1
Geng, C.-D.2
Vedeckis, W.V.3
-
14
-
-
20844437424
-
Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes
-
DOI 10.1016/j.molcel.2005.03.025, PII S1097276505012189
-
NZ Lu JA Cidlowski 2005 Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes Mol Cell 18 331 342 15866175 10.1016/j.molcel.2005.03.025 (Pubitemid 41350538)
-
(2005)
Molecular Cell
, vol.18
, Issue.3
, pp. 331-342
-
-
Lu, N.Z.1
Cidlowski, J.A.2
-
15
-
-
0022393794
-
Primary structure and expression of a functional human glucocorticoid receptor cDNA
-
DOI 10.1038/318635a0
-
SM Hollenberg C Weinberger ES Ong G Cerelli A Oro R Lebo EB Thompson MG Rosenfeld RM Evans 1985 Primary structure and expression of a functional human glucocorticoid receptor cDNA Nature 318 635 641 2867473 10.1038/318635a0 (Pubitemid 16172412)
-
(1985)
Nature
, vol.318
, Issue.6047
, pp. 635-641
-
-
Hollenberg, S.M.1
Weinberger, C.2
Ong, E.S.3
-
16
-
-
18444405534
-
Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition
-
DOI 10.1016/S0092-8674(02)00817-6
-
RK Bledsoe VG Montana TB Stanley CJ Delves CJ Apolito DD McKee TG Consler DJ Parks EL Stewart TM Willson MH Lambert JT Moore KH Pearce HE Xu 2002 Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition Cell 110 93 105 12151000 10.1016/S0092-8674(02)00817-6 (Pubitemid 34874609)
-
(2002)
Cell
, vol.110
, Issue.1
, pp. 93-105
-
-
Bledsoe, R.K.1
Montana, V.G.2
Stanley, T.B.3
Delves, C.J.4
Apolito, C.J.5
McKee, D.D.6
Consler, T.G.7
Parks, D.J.8
Stewart, E.L.9
Willson, T.M.10
Lambert, M.H.11
Moore, J.T.12
Pearce, K.H.13
Xu H.Eric14
-
18
-
-
0032575057
-
Atomic structure of progesterone complexed with its receptor
-
DOI 10.1038/30775
-
SP Williams PB Sigler 1998 Atomic structure of progesterone complexed with its receptor Nature 393 392 396 9620806 10.1038/30775 (Pubitemid 28269716)
-
(1998)
Nature
, vol.393
, Issue.6683
, pp. 392-396
-
-
Williams, S.P.1
Sigler, P.B.2
-
20
-
-
33744792310
-
Sensors and signals: A coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response
-
DOI 10.1101/gad.1424806
-
MG Rosenfeld VV Lunyak CK Glass 2006 Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response Genes Dev 20 1405 1428 16751179 10.1101/gad.1424806 (Pubitemid 43830648)
-
(2006)
Genes and Development
, vol.20
, Issue.11
, pp. 1405-1428
-
-
Rosenfeld, M.G.1
Lunyak, V.V.2
Glass, C.K.3
-
21
-
-
2542486258
-
Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors
-
DOI 10.1210/me.2003-0421
-
Q Wang JA Blackford Jr LN Song Y Huang S Cho SS Simons Jr 2004 Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors Mol Endocrinol 18 1376 1395 15016838 10.1210/me.2003-0421 (Pubitemid 38692177)
-
(2004)
Molecular Endocrinology
, vol.18
, Issue.6
, pp. 1376-1395
-
-
Wang, Q.1
Blackford Jr., J.A.2
Song, L.-N.3
Huang, Y.4
Cho, S.5
Simons Jr., S.S.6
-
22
-
-
0037135577
-
RU486-induced glucocorticoid receptor agonism is controlled by the receptor N terminus and by corepressor binding
-
DOI 10.1074/jbc.M203268200
-
M Schulz M Eggert A Baniahmad A Dostert T Heinzel R Renkawitz 2002 RU486-induced glucocorticoid receptor agonism is controlled by the receptor N terminus and by corepressor binding J Biol Chem 277 26238 26243 12011091 10.1074/jbc.M203268200 (Pubitemid 34967112)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.29
, pp. 26238-26243
-
-
Schulz, M.1
Eggert, M.2
Baniahmad, A.3
Dostert, A.4
Heinzel, T.5
Renkawitz, R.6
-
23
-
-
18144444807
-
DNA binding of the glucocorticoid receptor is not essential for survival
-
DOI 10.1016/S0092-8674(00)81183-6
-
HM Reichardt KH Kaestner J Tuckermann O Kretz O Wessely R Bock P Gass W Schmid P Herrlich P Angel G Schutz 1998 DNA binding of the glucocorticoid receptor is not essential for survival Cell 93 531 541 9604929 10.1016/S0092-8674(00)81183-6 (Pubitemid 28240715)
-
(1998)
Cell
, vol.93
, Issue.4
, pp. 531-541
-
-
Reichardt, H.M.1
Kaestner, K.H.2
Tuckermann, J.3
Kretz, O.4
Wessely, O.5
Bock, R.6
Gass, P.7
Schmid, W.8
Herrlich, P.9
Angel, P.10
Schutz, G.11
-
24
-
-
0029088326
-
Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation
-
7628695 10.1101/gad.9.13.1608
-
TJ Cole JA Blendy AP Monaghan K Krieglstein W Schmid A Aguzzi G Fantuzzi E Hummler K Unsicker G Schutz 1995 Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation Genes Dev 9 1608 1621 7628695 10.1101/gad.9.13.1608
-
(1995)
Genes Dev
, vol.9
, pp. 1608-1621
-
-
Cole, T.J.1
Blendy, J.A.2
Monaghan, A.P.3
Krieglstein, K.4
Schmid, W.5
Aguzzi, A.6
Fantuzzi, G.7
Hummler, E.8
Unsicker, K.9
Schutz, G.10
-
25
-
-
0037126620
-
Repression of inflammatory responses in the absence of DNA binding by the glucocorticoid receptor
-
DOI 10.1093/emboj/20.24.7168
-
HM Reichardt JP Tuckermann M Gottlicher M Vujic F Weih P Angel P Herrlich G Schutz 2001 Repression of inflammatory responses in the absence of DNA binding by the glucocorticoid receptor EMBO J 20 7168 7173 11742993 10.1093/emboj/20.24.7168 (Pubitemid 34062308)
-
(2001)
EMBO Journal
, vol.20
, Issue.24
, pp. 7168-7173
-
-
Reichardt, H.M.1
Tuckermann, J.P.2
Gottlicher, M.3
Vujic, M.4
Weih, F.5
Angel, P.6
Herrlich, P.7
Schutz, G.8
-
26
-
-
0025940872
-
Regulatory crosstalk at composite response elements
-
1776172 10.1016/0968-0004(91)90168-U
-
JN Miner KR Yamamoto 1991 Regulatory crosstalk at composite response elements Trends Biochem Sci 16 423 426 1776172 10.1016/0968-0004(91)90168-U
-
(1991)
Trends Biochem Sci
, vol.16
, pp. 423-426
-
-
Miner, J.N.1
Yamamoto, K.R.2
-
27
-
-
61449229273
-
Minireview: Latest perspectives on antiinflammatory actions of glucocorticoids
-
19095768 10.1210/me.2008-0283
-
K De Bosscher G Haegeman 2009 Minireview: latest perspectives on antiinflammatory actions of glucocorticoids Mol Endocrinol 23 281 291 19095768 10.1210/me.2008-0283
-
(2009)
Mol Endocrinol
, vol.23
, pp. 281-291
-
-
De Bosscher, K.1
Haegeman, G.2
-
28
-
-
0034965832
-
AP-1-glucocorticoid receptor crosstalk taken to a higher level
-
DOI 10.1677/joe.0.1690447
-
M Karin L Chang 2001 AP-1-glucocorticoid receptor crosstalk taken to a higher level J Endocrinol 169 447 451 11375114 10.1677/joe.0.1690447 (Pubitemid 32536977)
-
(2001)
Journal of Endocrinology
, vol.169
, Issue.3
, pp. 447-451
-
-
Karin, M.1
Chang, L.2
-
29
-
-
0030615201
-
Nuclear factor-κB - A pivotal transcription factor in chronic inflammatory diseases
-
DOI 10.1056/NEJM199704103361506
-
PJ Barnes M Karin 1997 Nuclear factor-κB: a pivotal transcription factor in chronic inflammatory diseases N Engl J Med 336 1066 1071 9091804 10.1056/NEJM199704103361506 (Pubitemid 27163860)
-
(1997)
New England Journal of Medicine
, vol.336
, Issue.15
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
30
-
-
0029737089
-
Molecular mechanisms of immunosuppression and anti-inflammatory activities by glucocorticoids
-
8756781
-
JA Didonato F Saatcioglu M Karin 1996 Molecular mechanisms of immunosuppression and anti-inflammatory activities by glucocorticoids Am J Respir Crit Care Med 154 S11 S15 8756781
-
(1996)
Am J Respir Crit Care Med
, vol.154
-
-
Didonato, J.A.1
Saatcioglu, F.2
Karin, M.3
-
31
-
-
34347255773
-
Cyclin-dependent kinase 5 differentially regulates the transcriptional activity of the glucocorticoid receptor through phosphorylation: Clinical implications for the nervous system response to glucocorticoids and stress
-
DOI 10.1210/me.2006-0345
-
T Kino T Ichijo ND Amin S Kesavapany Y Wang N Kim S Rao A Player YL Zheng MJ Garabedian E Kawasaki HC Pant GP Chrousos 2007 Cyclin-dependent kinase 5 differentially regulates the transcriptional activity of the glucocorticoid receptor through phosphorylation: clinical implications for the nervous system response to glucocorticoids and stress Mol Endocrinol 21 1552 1568 17440046 10.1210/me.2006-0345 (Pubitemid 47001081)
-
(2007)
Molecular Endocrinology
, vol.21
, Issue.7
, pp. 1552-1568
-
-
Kino, T.1
Ichijo, T.2
Amin, N.D.3
Kesavapany, S.4
Wang, Y.5
Kim, N.6
Rao, S.7
Player, A.8
Zheng, Y.-L.9
Garabedian, M.J.10
Kawasaki, E.11
Pant, H.C.12
Chrousos, G.P.13
-
32
-
-
41549093691
-
Discovery of a functional glucocorticoid receptor β-isoform in zebrafish
-
18096659 10.1210/en.2007-1364
-
MJ Schaaf D Champagne IH van Laanen DC van Wijk AH Meijer OC Meijer HP Spaink MK Richardson 2008 Discovery of a functional glucocorticoid receptor β-isoform in zebrafish Endocrinology 149 1591 1599 18096659 10.1210/en.2007-1364
-
(2008)
Endocrinology
, vol.149
, pp. 1591-1599
-
-
Schaaf, M.J.1
Champagne, D.2
Van Laanen, I.H.3
Van Wijk, D.C.4
Meijer, A.H.5
Meijer, O.C.6
Spaink, H.P.7
Richardson, M.K.8
-
33
-
-
0030664771
-
Absence of glucocorticoid receptor-β in mice
-
DOI 10.1074/jbc.272.42.26665
-
C Otto HM Reichardt G Schutz 1997 Absence of glucocorticoid receptor-β in mice J Biol Chem 272 26665 26668 9334249 10.1074/jbc.272.42. 26665 (Pubitemid 27458891)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.42
, pp. 26665-26668
-
-
Otto, C.1
Reichardt, H.M.2
Schutz, G.3
-
34
-
-
11244329291
-
The human glucocorticoid receptor (hGR) β isoform suppresses the transcriptional activity of hGRα by interfering with formation of active coactivator complexes
-
DOI 10.1210/me.2004-0112
-
E Charmandari GP Chrousos T Ichijo N Bhattacharyya A Vottero E Souvatzoglou T Kino 2005 The human glucocorticoid receptor (hGR) β isoform suppresses the transcriptional activity of hGRα by interfering with formation of active coactivator complexes Mol Endocrinol 19 52 64 15459252 10.1210/me.2004-0112 (Pubitemid 40065958)
-
(2005)
Molecular Endocrinology
, vol.19
, Issue.1
, pp. 52-64
-
-
Charmandari, E.1
Chrousos, G.P.2
Ichijo, T.3
Bhattacharyya, N.4
Vottero, A.5
Souvatzoglou, E.6
Kino, T.7
-
35
-
-
0029993518
-
The human glucocorticoid receptor β isoform. Expression, biochemical properties, and putative function
-
DOI 10.1074/jbc.271.16.9550
-
RH Oakley M Sar JA Cidlowski 1996 The human glucocorticoid receptor β isoform. Expression, biochemical properties, and putative function J Biol Chem 271 9550 9559 8621628 10.1074/jbc.271.16.9550 (Pubitemid 26137360)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.16
, pp. 9550-9559
-
-
Oakley, R.H.1
Sar, M.2
Cidlowski, J.A.3
-
36
-
-
70249136172
-
Naturally occurring C-terminal splice variants of nuclear receptors
-
19636396
-
M van der Vaart MJ Schaaf 2009 Naturally occurring C-terminal splice variants of nuclear receptors Nucl Recept Signal 7 e007 19636396
-
(2009)
Nucl Recept Signal
, vol.7
, pp. 007
-
-
Van Der Vaart, M.1
Schaaf, M.J.2
-
37
-
-
0032145924
-
Molecular cloning and characterization of human estrogen receptor βcx: A potential inhibitor of estrogen action in human
-
DOI 10.1093/nar/26.15.3505
-
S Ogawa S Inoue T Watanabe A Orimo T Hosoi Y Ouchi M Muramatsu 1998 Molecular cloning and characterization of human estrogen receptor βcx: a potential inhibitor of estrogen action in human Nucleic Acids Res 26 3505 3512 9671811 10.1093/nar/26.15.3505 (Pubitemid 28347221)
-
(1998)
Nucleic Acids Research
, vol.26
, Issue.15
, pp. 3505-3512
-
-
Ogawa, S.1
Inoue, S.2
Watanabe, T.3
Orimo, A.4
Hosoi, T.5
Ouchi, Y.6
Muramatsu, M.7
-
38
-
-
0023525848
-
A novel thyroid hormone receptor encoded by a cDNA clone from a human testis library
-
3672126 10.1126/science.3672126
-
D Benbrook M Pfahl 1987 A novel thyroid hormone receptor encoded by a cDNA clone from a human testis library Science 238 788 791 3672126 10.1126/science.3672126
-
(1987)
Science
, vol.238
, pp. 788-791
-
-
Benbrook, D.1
Pfahl, M.2
-
39
-
-
15844386531
-
Intron retention generates a novel isoform of the murine vitamin D receptor that acts in a dominant negative way on the vitamin D signaling pathway
-
8668154
-
K Ebihara Y Masuhiro T Kitamoto M Suzawa Y Uematsu T Yoshizawa T Ono H Harada K Matsuda T Hasegawa S Masushige S Kato 1996 Intron retention generates a novel isoform of the murine vitamin D receptor that acts in a dominant negative way on the vitamin D signaling pathway Mol Cell Biol 16 3393 3400 8668154
-
(1996)
Mol Cell Biol
, vol.16
, pp. 3393-3400
-
-
Ebihara, K.1
Masuhiro, Y.2
Kitamoto, T.3
Suzawa, M.4
Uematsu, Y.5
Yoshizawa, T.6
Ono, T.7
Harada, H.8
Matsuda, K.9
Hasegawa, T.10
Masushige, S.11
Kato, S.12
-
40
-
-
4344562884
-
Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor
-
DOI 10.1186/1478-1336-2-1
-
KA Arnold M Eichelbaum O Burk 2004 Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor Nucl Recept 2 1 15043764 10.1186/1478-1336-2-1 (Pubitemid 39130379)
-
(2004)
Nuclear Receptor
, vol.2
, pp. 1
-
-
Katja, A.A.1
Eichelbaum, M.2
Burk, O.3
-
41
-
-
2542448014
-
Generation of two distinct functional isoforms of dosage-sensitive sex reversal-adrenal hypoplasia congenita-critical region on the X chromosome gene 1 (DAX-1) by alternative splicing
-
DOI 10.1210/me.2003-0176
-
A Hossain C Li GF Saunders 2004 Generation of two distinct functional isoforms of dosage-sensitive sex reversal-adrenal hypoplasia congenita-critical region on the X chromosome gene 1 (DAX-1) by alternative splicing Mol Endocrinol 18 1428 1437 15044589 10.1210/me.2003-0176 (Pubitemid 38692180)
-
(2004)
Molecular Endocrinology
, vol.18
, Issue.6
, pp. 1428-1437
-
-
Hossain, A.1
Li, C.2
Saunders, G.F.3
-
43
-
-
0029116937
-
NOR-2 (neuron-derived orphan receptor), a brain zinc finger protein, is highly induced during liver regeneration
-
7556683 10.1016/0014-5793(95)00998-O
-
I Petropoulos D Part A Ochoa MM Zakin E Lamas 1995 NOR-2 (neuron-derived orphan receptor), a brain zinc finger protein, is highly induced during liver regeneration FEBS Lett 372 273 278 7556683 10.1016/0014-5793(95)00998-O
-
(1995)
FEBS Lett
, vol.372
, pp. 273-278
-
-
Petropoulos, I.1
Part, D.2
Ochoa, A.3
Zakin, M.M.4
Lamas, E.5
-
44
-
-
0033304779
-
A truncated human peroxisome proliferator-activated receptor α splice variant with dominant negative activity
-
10478844 10.1210/me.13.9.1535
-
P Gervois IP Torra G Chinetti T Grotzinger G Dubois JC Fruchart J Fruchart-Najib E Leitersdorf B Staels 1999 A truncated human peroxisome proliferator-activated receptor α splice variant with dominant negative activity Mol Endocrinol 13 1535 1549 10478844 10.1210/me.13.9.1535
-
(1999)
Mol Endocrinol
, vol.13
, pp. 1535-1549
-
-
Gervois, P.1
Torra, I.P.2
Chinetti, G.3
Grotzinger, T.4
Dubois, G.5
Fruchart, J.C.6
Fruchart-Najib, J.7
Leitersdorf, E.8
Staels, B.9
-
45
-
-
22544441159
-
A novel peroxisome proliferator-activated receptor γ isoform with dominant negative activity generated by alternative splicing
-
DOI 10.1074/jbc.M502716200
-
L Sabatino A Casamassimi G Peluso MV Barone D Capaccio C Migliore P Bonelli A Pedicini A Febbraro A Ciccodicola V Colantuoni 2005 A novel peroxisome proliferator-activated receptor γ isoform with dominant negative activity generated by alternative splicing J Biol Chem 280 26517 26525 15857827 10.1074/jbc.M502716200 (Pubitemid 41022249)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.28
, pp. 26517-26525
-
-
Sabatino, L.1
Casamassimi, A.2
Peluso, G.3
Barone, M.V.4
Capaccio, D.5
Migliore, C.6
Bonelli, P.7
Pedicini, A.8
Febbraro, A.9
Ciccodicola, A.10
Colantuoni, V.11
-
46
-
-
33746423134
-
Divergent expression and function of glucocorticoid receptor β in human monocytes and T cells
-
DOI 10.1189/jlb.0805466
-
LB Li DY Leung CF Hall E Goleva 2006 Divergent expression and function of glucocorticoid receptor β in human monocytes and T cells J Leukoc Biol 79 818 827 16461744 10.1189/jlb.0805466 (Pubitemid 44835614)
-
(2006)
Journal of Leukocyte Biology
, vol.79
, Issue.4
, pp. 818-827
-
-
Li, N.-B.1
Leung, D.Y.M.2
Hall, C.F.3
Goleva, E.4
-
47
-
-
33644811218
-
Regulation of glucocorticoid responsiveness in glaucomatous trabecular meshwork cells by glucocorticoid receptor-β
-
DOI 10.1167/iovs.05-0571
-
X Zhang AF Clark T Yorio 2005 Regulation of glucocorticoid responsiveness in glaucomatous trabecular meshwork cells by glucocorticoid receptor-β Invest Ophthalmol Vis Sci 46 4607 4616 16303956 10.1167/iovs.05-0571 (Pubitemid 44264561)
-
(2005)
Investigative Ophthalmology and Visual Science
, vol.46
, Issue.12
, pp. 4607-4616
-
-
Zhang, X.1
Clark, A.F.2
Yorio, T.3
-
48
-
-
0033600936
-
The dominant negative activity of the human glucocorticoid receptor β isoform. Specificity and mechanisms of action
-
DOI 10.1074/jbc.274.39.27857
-
RH Oakley CM Jewell MR Yudt DM Bofetiado JA Cidlowski 1999 The dominant negative activity of the human glucocorticoid receptor β isoform. Specificity and mechanisms of action J Biol Chem 274 27857 27866 10488132 10.1074/jbc.274.39.27857 (Pubitemid 29458040)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.39
, pp. 27857-27866
-
-
Oakleyt, R.H.1
Jewell, C.M.2
Yudt, M.R.3
Bofetiado, D.M.4
Cidlowski, J.A.5
-
50
-
-
0034767551
-
A human glucocorticoid receptor gene variant that increases the stability of the glucocorticoid receptor β-isoform mRNA is associated with rheumatoid arthritis
-
11708406
-
RH Derijk MJ Schaaf G Turner NA Datson E Vreugdenhil J Cidlowski ER de Kloet P Emery EM Sternberg SD Detera-Wadleigh 2001 A human glucocorticoid receptor gene variant that increases the stability of the glucocorticoid receptor β-isoform mRNA is associated with rheumatoid arthritis J Rheumatol 28 2383 2388 11708406
-
(2001)
J Rheumatol
, vol.28
, pp. 2383-2388
-
-
Derijk, R.H.1
Schaaf, M.J.2
Turner, G.3
Datson, N.A.4
Vreugdenhil, E.5
Cidlowski, J.6
De Kloet, E.R.7
Emery, P.8
Sternberg, E.M.9
Detera-Wadleigh, S.D.10
-
51
-
-
25144471244
-
Increased expression of glucocorticoid receptor β messenger RNA in patients with ankylosing spondylitis
-
16134770
-
CK Lee EY Lee YS Cho KA Moon B Yoo HB Moon 2005 Increased expression of glucocorticoid receptor β messenger RNA in patients with ankylosing spondylitis Korean J Intern Med 20 146 151 16134770
-
(2005)
Korean J Intern Med
, vol.20
, pp. 146-151
-
-
Lee, C.K.1
Lee, E.Y.2
Cho, Y.S.3
Moon, K.A.4
Yoo, B.5
Moon, H.B.6
-
53
-
-
0037244071
-
Expression of the glucocorticoid receptor alpha and beta isoforms in human nasal mucosa and polyp epithelia cells
-
DOI 10.1053/rmed.2002.1406
-
L Pujols J Mullol P Benitez A Torrego A Xaubet J de Haro C Picado 2003 Expression of the glucocorticoid receptor α and β isoforms in human nasal mucosa and polyp epithelial cells Respir Med 97 90 96 12556018 10.1053/rmed.2002.1406 (Pubitemid 36109119)
-
(2003)
Respiratory Medicine
, vol.97
, Issue.1
, pp. 90-96
-
-
Pujols, L.1
Mullol, J.2
Benitez, P.3
Torrego, A.4
Xaubet, A.5
De Haro, J.6
Picado, C.7
-
54
-
-
0033608230
-
Imbalanced expression of the glucocorticoid receptor isoforms in cultured lymphocytes from a patient with systemic glucocorticoid resistance and chronic lymphocytic leukemia
-
DOI 10.1006/bbrc.1998.9980
-
H Shahidi A Vottero CA Stratakis SE Taymans M Karl CA Longui GP Chrousos WH Daughaday SA Gregory JM Plate 1999 Imbalanced expression of the glucocorticoid receptor isoforms in cultured lymphocytes from a patient with systemic glucocorticoid resistance and chronic lymphocytic leukemia Biochem Biophys Res Commun 254 559 565 9920778 10.1006/bbrc.1998.9980 (Pubitemid 29290505)
-
(1999)
Biochemical and Biophysical Research Communications
, vol.254
, Issue.3
, pp. 559-565
-
-
Shahidi, H.1
Vottero, A.2
Stratakis, C.A.3
Taymans, S.E.4
Karl, M.5
Longui, C.A.6
Chrousos, G.P.7
Daughaday, W.H.8
Gregory, S.A.9
Plate, J.M.D.10
-
56
-
-
0030702823
-
Association of glucocorticoid insensitivity with increased expression of glucocorticoid receptor β
-
DOI 10.1084/jem.186.9.1567
-
DY Leung Q Hamid A Vottero SJ Szefler W Surs E Minshall GP Chrousos DJ Klemm 1997 Association of glucocorticoid insensitivity with increased expression of glucocorticoid receptor β J Exp Med 186 1567 1574 9348314 10.1084/jem.186.9.1567 (Pubitemid 27479816)
-
(1997)
Journal of Experimental Medicine
, vol.186
, Issue.9
, pp. 1567-1574
-
-
Leung, D.Y.M.1
Hamid, Q.2
Vottero, A.3
Szefler, S.J.4
Surs, W.5
Minshall, E.6
Chrousos, G.P.7
Klemm, D.J.8
-
57
-
-
0035810930
-
Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative β isoform: A mechanism for the generation of glucocorticoid resistance
-
DOI 10.1073/pnas.121455098
-
JC Webster RH Oakley CM Jewell JA Cidlowski 2001 Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative β isoform: a mechanism for the generation of glucocorticoid resistance Proc Natl Acad Sci USA 98 6865 6870 11381138 10.1073/pnas.121455098 (Pubitemid 32538308)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.12
, pp. 6865-6870
-
-
Webster, J.C.1
Oakley, R.H.2
Jewell, C.M.3
Cidlowski, J.A.4
-
58
-
-
0038035100
-
Serine-arginine-rich protein p30 directs alternative splicing of glucocorticoid receptor pre-mRNA to glucocorticoid receptor β in neutrophils
-
DOI 10.1074/jbc.M300824200
-
Q Xu DY Leung KO Kisich 2003 Serine-arginine-rich protein p30 directs alternative splicing of glucocorticoid receptor pre-mRNA to glucocorticoid receptor β in neutrophils J Biol Chem 278 27112 27118 12738786 10.1074/jbc.M300824200 (Pubitemid 36876866)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.29
, pp. 27112-27118
-
-
Xu, Q.1
Leung, D.Y.M.2
Kisich, K.O.3
-
59
-
-
0035809314
-
High constitutive glucocorticoid receptor β in human neutrophils enables them to reduce their spontaneous rate of cell death in response to corticosteroids
-
DOI 10.1084/jem.193.5.585
-
I Strickland K Kisich PJ Hauk A Vottero GP Chrousos DJ Klemm DY Leung 2001 High constitutive glucocorticoid receptor β in human neutrophils enables them to reduce their spontaneous rate of cell death in response to corticosteroids J Exp Med 193 585 593 11238589 10.1084/jem.193.5.585 (Pubitemid 32539555)
-
(2001)
Journal of Experimental Medicine
, vol.193
, Issue.5
, pp. 585-593
-
-
Strickland, I.1
Kisich, K.2
Hauk, P.J.3
Vottero, A.4
Chrousos, G.P.5
Klemm, D.J.6
Leung, D.Y.M.7
-
60
-
-
0036392066
-
Quantitative analysis for human glucocorticoid receptor α/β mRNA in IBD
-
12207914 10.1016/S0006-291X(02)02030-2
-
F Orii T Ashida M Nomura A Maemoto T Fujiki T Ayabe S Imai Y Saitoh Y Kohgo 2002 Quantitative analysis for human glucocorticoid receptor α/β mRNA in IBD Biochem Biophys Res Commun 296 1286 1294 12207914 10.1016/S0006-291X(02)02030-2
-
(2002)
Biochem Biophys Res Commun
, vol.296
, pp. 1286-1294
-
-
Orii, F.1
Ashida, T.2
Nomura, M.3
Maemoto, A.4
Fujiki, T.5
Ayabe, T.6
Imai, S.7
Saitoh, Y.8
Kohgo, Y.9
-
61
-
-
41449101856
-
Cytokines induce an early steroid resistance in airway smooth muscle cells: Novel role of interferon regulatory factor-1
-
DOI 10.1165/rcmb.2007-0226OC
-
O Tliba G Damera A Banerjee S Gu H Baidouri S Keslacy Y Amrani 2008 Cytokines induce an early steroid resistance in airway smooth muscle cells: novel role of interferon regulatory factor-1 Am J Respir Cell Mol Biol 38 463 472 17947510 10.1165/rcmb.2007-0226OC (Pubitemid 351758693)
-
(2008)
American Journal of Respiratory Cell and Molecular Biology
, vol.38
, Issue.4
, pp. 463-472
-
-
Tliba, O.1
Damera, G.2
Banerjee, A.3
Gu, S.4
Baidouri, H.5
Keslacy, S.6
Amrani, Y.7
-
62
-
-
58149392537
-
Glucocorticoid receptor gene variant in the 3 untranslated region is associated with multiple measures of blood pressure
-
18854398 10.1210/jc.2008-1089
-
CC Chung L Shimmin S Natarajan CL Hanis E Boerwinkle JE Hixson 2009 Glucocorticoid receptor gene variant in the 3 untranslated region is associated with multiple measures of blood pressure J Clin Endocrinol Metab 94 268 276 18854398 10.1210/jc.2008-1089
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 268-276
-
-
Chung, C.C.1
Shimmin, L.2
Natarajan, S.3
Hanis, C.L.4
Boerwinkle, E.5
Hixson, J.E.6
-
63
-
-
38349076030
-
Glucocorticoid receptor gene and risk of cardiovascular disease
-
18195193 10.1001/archinternmed.2007.41
-
EL van den Akker JW Koper EF van Rossum MJ Dekker H Russcher FH de Jong AG Uitterlinden A Hofman HA Pols JC Witteman SW Lamberts 2008 Glucocorticoid receptor gene and risk of cardiovascular disease Arch Intern Med 168 33 39 18195193 10.1001/archinternmed.2007.41
-
(2008)
Arch Intern Med
, vol.168
, pp. 33-39
-
-
Van Den Akker, E.L.1
Koper, J.W.2
Van Rossum, E.F.3
Dekker, M.J.4
Russcher, H.5
De Jong, F.H.6
Uitterlinden, A.G.7
Hofman, A.8
Pols, H.A.9
Witteman, J.C.10
Lamberts, S.W.11
-
64
-
-
33745783528
-
Staphylococcus aureus nasal carriage is associated with glucocorticoid receptor gene polymorphisms
-
DOI 10.1086/506367
-
EL van den Akker JL Nouwen DC Melles EF van Rossum JW Koper AG Uitterlinden A Hofman HA Verbrugh HA Pols SW Lamberts A van Belkum 2006 Staphylococcus aureus nasal carriage is associated with glucocorticoid receptor gene polymorphisms J Infect Dis 194 814 818 16941349 10.1086/506367 (Pubitemid 44344130)
-
(2006)
Journal of Infectious Diseases
, vol.194
, Issue.6
, pp. 814-818
-
-
Van Den Akker, E.L.T.1
Nouwen, J.L.2
Melles, D.C.3
Van Rossum, E.F.C.4
Koper, J.W.5
Uitterlinden, A.G.6
Hofman, A.7
Verbrugh, H.A.8
Pols, H.A.9
Lamberts, S.W.J.10
Van Belkum, A.11
-
65
-
-
0033999965
-
Recruitment of the SWI-SNF chromatin remodeling complex as a mechanism of gene activation by the glucocorticoid receptor τ1 activation domain
-
DOI 10.1128/MCB.20.6.2004-2013.2000
-
AE Wallberg KE Neely AH Hassan JA Gustafsson JL Workman AP Wright 2000 Recruitment of the SWI-SNF chromatin remodeling complex as a mechanism of gene activation by the glucocorticoid receptor tau1 activation domain Mol Cell Biol 20 2004 2013 10688647 10.1128/MCB.20.6.2004-2013.2000 (Pubitemid 30123816)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.6
, pp. 2004-2013
-
-
Wallberg, A.E.1
Neely, K.E.2
Hassan, A.H.3
Gustafsson, J.-A.4
Workman, J.L.5
Wright, A.P.H.6
-
66
-
-
0032766843
-
Multiple signal input and output domains of the 160-kilodalton nuclear receptor coactivator proteins
-
10454563
-
H Ma H Hong SM Huang RA Irvine P Webb PJ Kushner GA Coetzee MR Stallcup 1999 Multiple signal input and output domains of the 160-kilodalton nuclear receptor coactivator proteins Mol Cell Biol 19 6164 6173 10454563
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6164-6173
-
-
Ma, H.1
Hong, H.2
Huang, S.M.3
Irvine, R.A.4
Webb, P.5
Kushner, P.J.6
Coetzee, G.A.7
Stallcup, M.R.8
-
67
-
-
0032230350
-
Estrogen receptor activation function 1 works by binding p160 coactivator proteins
-
9773983 10.1210/me.12.10.1605
-
P Webb P Nguyen J Shinsako C Anderson W Feng MP Nguyen D Chen SM Huang S Subramanian E McKinerney BS Katzenellenbogen MR Stallcup PJ Kushner 1998 Estrogen receptor activation function 1 works by binding p160 coactivator proteins Mol Endocrinol 12 1605 1618 9773983 10.1210/me.12.10.1605
-
(1998)
Mol Endocrinol
, vol.12
, pp. 1605-1618
-
-
Webb, P.1
Nguyen, P.2
Shinsako, J.3
Anderson, C.4
Feng, W.5
Nguyen, M.P.6
Chen, D.7
Huang, S.M.8
Subramanian, S.9
McKinerney, E.10
Katzenellenbogen, B.S.11
Stallcup, M.R.12
Kushner, P.J.13
-
68
-
-
0032793296
-
Histone acetyltransferase complexes can mediate transcriptional activation by the major glucocorticoid receptor activation domain
-
10454542
-
AE Wallberg KE Neely JA Gustafsson JL Workman AP Wright PA Grant 1999 Histone acetyltransferase complexes can mediate transcriptional activation by the major glucocorticoid receptor activation domain Mol Cell Biol 19 5952 5959 10454542
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5952-5959
-
-
Wallberg, A.E.1
Neely, K.E.2
Gustafsson, J.A.3
Workman, J.L.4
Wright, A.P.5
Grant, P.A.6
-
69
-
-
0033214780
-
Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins
-
DOI 10.1093/emboj/18.19.5380
-
AB Hittelman D Burakov JA Iniguez-Lluhi LP Freedman MJ Garabedian 1999 Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins EMBO J 18 5380 5388 10508170 10.1093/emboj/18.19. 5380 (Pubitemid 29465587)
-
(1999)
EMBO Journal
, vol.18
, Issue.19
, pp. 5380-5388
-
-
Hittelman, A.B.1
Burakov, D.2
Iniguez-Lluhi, J.A.3
Freedman, L.P.4
Garabedian, M.J.5
-
70
-
-
0033515637
-
A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex
-
10199399 10.1016/S0092-8674(00)80711-4
-
RB Lanz NJ McKenna SA Onate U Albrecht J Wong SY Tsai MJ Tsai BW O'Malley 1999 A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex Cell 97 17 27 10199399 10.1016/S0092-8674(00)80711-4
-
(1999)
Cell
, vol.97
, pp. 17-27
-
-
Lanz, R.B.1
McKenna, N.J.2
Onate, S.A.3
Albrecht, U.4
Wong, J.5
Tsai, S.Y.6
Tsai, M.J.7
O'Malley, B.W.8
-
71
-
-
0036013805
-
Overexpression of the human glucocorticoid receptor α and β isoforms inhibits AP-1 and NF-κB activities hormone independently
-
DOI 10.1007/s00109-001-0302-6
-
C Gougat D Jaffuel R Gagliardo C Henriquet J Bousquet P Demoly M Mathieu 2002 Overexpression of the human glucocorticoid receptor α and β isoforms inhibits AP-1 and NF-κB activities hormone independently J Mol Med 80 309 318 12021843 10.1007/s00109-001-0302-6 (Pubitemid 34516369)
-
(2002)
Journal of Molecular Medicine
, vol.80
, Issue.5
, pp. 309-318
-
-
Gougat, C.1
Jaffuel, D.2
Gagliardo, R.3
Henriquet, C.4
Bousquet, J.5
Demoly, P.6
Mathieu, M.7
-
72
-
-
38149122816
-
The glucocorticoid receptor β isoform can mediate transcriptional repression by recruiting histone deacetylases
-
18028994 10.1016/j.jaci.2007.09.010
-
A Kelly H Bowen YK Jee N Mahfiche C Soh T Lee C Hawrylowicz P Lavender 2008 The glucocorticoid receptor β isoform can mediate transcriptional repression by recruiting histone deacetylases J Allergy Clin Immunol 121 203 208e1 18028994 10.1016/j.jaci.2007.09.010
-
(2008)
J Allergy Clin Immunol
, vol.121
-
-
Kelly, A.1
Bowen, H.2
Jee, Y.K.3
Mahfiche, N.4
Soh, C.5
Lee, T.6
Hawrylowicz, C.7
Lavender, P.8
-
73
-
-
18144424777
-
Gene regulation by the glucocorticoid receptor: Structure:function relationship
-
DOI 10.1016/j.jsbmb.2004.12.046, PII S0960076005000671
-
R Kumar EB Thompson 2005 Gene regulation by the glucocorticoid receptor: structure: function relationship J Steroid Biochem Mol Biol 94 383 394 15876404 10.1016/j.jsbmb.2004.12.046 (Pubitemid 40616400)
-
(2005)
Journal of Steroid Biochemistry and Molecular Biology
, vol.94
, Issue.5
, pp. 383-394
-
-
Kumar, R.1
Thompson, E.B.2
-
74
-
-
0035834722
-
2- and COOH-terminal Interaction Inhibits p160 Coactivator Recruitment by Activation Function 2
-
DOI 10.1074/jbc.M107492200
-
B He NT Bowen JT Minges EM Wilson 2001 Androgen-induced NH2- and COOH-terminal Interaction Inhibits p160 coactivator recruitment by activation function 2 J Biol Chem 276 42293 42301 11551963 10.1074/jbc.M107492200 (Pubitemid 37371140)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.45
, pp. 42293-42301
-
-
He, B.1
Bowen, N.T.2
Minges, J.T.3
Wilson, E.M.4
-
75
-
-
0038265311
-
The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism
-
DOI 10.1074/jbc.M212711200
-
B Kauppi C Jakob M Farnegardh J Yang H Ahola M Alarcon K Calles O Engstrom J Harlan S Muchmore AK Ramqvist S Thorell L Ohman J Greer JA Gustafsson J Carlstedt-Duke M Carlquist 2003 The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism J Biol Chem 278 22748 22754 12686538 10.1074/jbc.M212711200 (Pubitemid 36830335)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.25
, pp. 22748-22754
-
-
Kauppi, B.1
Jakob, C.2
Farnegardh, M.3
Yang, J.4
Ahola, H.5
Alarcon, M.6
Calles, K.7
Engstrom, O.8
Harlan, J.9
Muchmore, S.10
Ramqvist, A.-K.11
Thorell, S.12
Ohman, L.13
Greer, J.14
Gustafsson, J.-A.15
Carlstedt-Duke, J.16
Carlquist, M.17
|