The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A

Nature Medicine

Volumn 14, Issue 9, 2008, Pages 931-938

  Faul, Christian ^a,b   Donnelly, Mary ^a,b   Merscher Gomez, Sandra ^a,b   Chang, Yoon Hee ^b,e   Franz, Stefan ^b,f   Delfgaauw, Jacqueline ^b,g   Chang, Jer Ming ^c   Choi, Hoon Young ^b   Campbell, Kirk N ^a,b   Kim, Kwanghee ^b   Reiser, Jochen ^a,d   Mundel, Peter ^a,b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e YALE NEW HAVEN HOSPITAL   (United States)

^f Roche Pharma Schweiz AG   (Switzerland)

^g GRÜNENTHAL GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CALCINEURIN; CATHEPSIN L; CYCLOSPORIN A; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SYNAPTOPODIN; TRANSCRIPTION FACTOR NFAT;

ARTICLE; CELL PROTECTION; DEPHOSPHORYLATION; DRUG EFFECT; DRUG MECHANISM; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY; KIDNEY DISEASE; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEINURIA; SIGNAL TRANSDUCTION; STRESS FIBER;

14-3-3 PROTEINS; ACTINS; ANIMALS; CALCINEURIN; CYCLOSPORINE; CYTOSKELETON; GENE EXPRESSION REGULATION; IMMUNOSUPPRESSIVE AGENTS; MICE; MICE, TRANSGENIC; MICROFILAMENT PROTEINS; PHOSPHORYLATION; PODOCYTES; PROTEINURIA; SIGNAL TRANSDUCTION;

EID: 51349162919     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.1857     Document Type: Article

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