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Volumn 4, Issue NOV, 2013, Pages

New frontiers in the intrarenal renin-angiotensin system: A critical review of classical and new paradigms

Author keywords

ACE2; Angiotensin 1 converting enzyme; Angiotensin II receptor; Blood pressure; Hypertension; Kidney; Proximal tubule; Signal transduction

Indexed keywords


EID: 84890263719     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2013.00166     Document Type: Article
Times cited : (101)

References (187)
  • 1
    • 84979105364 scopus 로고
    • Niere und Kreislauf
    • doi: 10.1111/j.1748-1716.1898.tb00272.x
    • Tigerstedt R, Bergman PG. Niere und Kreislauf. Scand Arch Physiol (1898) 8:223-71. doi: 10.1111/j.1748-1716.1898.tb00272.x
    • (1898) Scand Arch Physiol , vol.8 , pp. 223-271
    • Tigerstedt, R.1    Bergman, P.G.2
  • 2
    • 0037667643 scopus 로고    scopus 로고
    • Newly recognized components of the renin-angiotensin system: potential roles in cardiovascular and renal regulation
    • doi:10.1210/er.2003-0001
    • Carey RM, Siragy HM. Newly recognized components of the renin-angiotensin system: potential roles in cardiovascular and renal regulation. Endocr Rev (2003) 24(3):261-71. doi:10.1210/er.2003-0001
    • (2003) Endocr Rev , vol.24 , Issue.3 , pp. 261-271
    • Carey, R.M.1    Siragy, H.M.2
  • 4
    • 33845210475 scopus 로고    scopus 로고
    • Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney
    • doi:10.1073/pnas.0605545103
    • Crowley SD, Gurley SB, Herrera MJ, Ruiz P, Griffiths R, Kumar AP, et al. Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney. Proc Natl Acad Sci U S A (2006) 103(47):17985-90. doi:10.1073/pnas.0605545103
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.47 , pp. 17985-17990
    • Crowley, S.D.1    Gurley, S.B.2    Herrera, M.J.3    Ruiz, P.4    Griffiths, R.5    Kumar, A.P.6
  • 6
    • 0343627693 scopus 로고    scopus 로고
    • Angiotensin II and the heart: on the intracrine renin-angiotensin system
    • doi:10.1161/01.HYP.35.6.1183
    • De Mello WC, Danser AH. Angiotensin II and the heart: on the intracrine renin-angiotensin system. Hypertension (2000) 35(6):1183-8. doi:10.1161/01.HYP.35.6.1183
    • (2000) Hypertension , vol.35 , Issue.6 , pp. 1183-1188
    • De Mello, W.C.1    Danser, A.H.2
  • 7
    • 0035048905 scopus 로고    scopus 로고
    • Theodore Cooper Lecture: tissue angiotensin and pathobiology of vascular disease: a unifying hypothesis
    • doi:10.1161/01.HYP.37.4.1047
    • Dzau VJ. Theodore Cooper Lecture: tissue angiotensin and pathobiology of vascular disease: a unifying hypothesis. Hypertension (2001) 37(4):1047-52. doi:10.1161/01.HYP.37.4.1047
    • (2001) Hypertension , vol.37 , Issue.4 , pp. 1047-1052
    • Dzau, V.J.1
  • 8
    • 34548851716 scopus 로고    scopus 로고
    • Emerging evidence for a functional angiotensin-converting enzyme 2-angiotensin-(1-7)-MAS receptor axis: more than regulation of blood pressure?
    • Chappell MC. Emerging evidence for a functional angiotensin-converting enzyme 2-angiotensin-(1-7)-MAS receptor axis: more than regulation of blood pressure? Hypertension (2007) 50(4):596-9. doi:10.1161/HYPERTENSIONAHA.106.076216
    • (2007) Hypertension , vol.50 , Issue.4 , pp. 596-599
    • Chappell, M.C.1
  • 9
    • 33644970894 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 and angiotensin-(1-7): an evolving story in cardiovascular regulation
    • doi:10.1161/01.HYP.0000196268.08909.fb
    • Ferrario CM. Angiotensin-converting enzyme 2 and angiotensin-(1-7): an evolving story in cardiovascular regulation. Hypertension (2006) 47(3):515-21. doi:10.1161/01.HYP.0000196268.08909.fb
    • (2006) Hypertension , vol.47 , Issue.3 , pp. 515-521
    • Ferrario, C.M.1
  • 11
    • 27444447364 scopus 로고    scopus 로고
    • Renin, proreinin and the putative (pro)renin receptor
    • doi:10.1161/01.HYP.0000186329.92187.2e
    • Danser AH, Deinum J. Renin, proreinin and the putative (pro)renin receptor. Hypertension (2005) 46:1069-76. doi:10.1161/01.HYP.0000186329.92187.2e
    • (2005) Hypertension , vol.46 , pp. 1069-1076
    • Danser, A.H.1    Deinum, J.2
  • 12
    • 79251621720 scopus 로고    scopus 로고
    • Renin, (pro)renin and receptor: an update
    • doi:10.1042/CS20100432
    • Nguyen G. Renin, (pro)renin and receptor: an update. Clin Sci (Lond) (2011) 120(5):169-78. doi:10.1042/CS20100432
    • (2011) Clin Sci (Lond) , vol.120 , Issue.5 , pp. 169-178
    • Nguyen, G.1
  • 13
    • 84857060472 scopus 로고    scopus 로고
    • The interaction between prorenin, renin and the (pro)renin receptor: time to rethink the role in hypertension
    • doi:10.1097/MNH.0b013e3283500927
    • Reudelhuber TL. The interaction between prorenin, renin and the (pro)renin receptor: time to rethink the role in hypertension. Curr Opin Nephrol Hypertens (2012) 21(2):137-41. doi:10.1097/MNH.0b013e3283500927
    • (2012) Curr Opin Nephrol Hypertens , vol.21 , Issue.2 , pp. 137-141
    • Reudelhuber, T.L.1
  • 14
    • 78649737267 scopus 로고    scopus 로고
    • Angiotensin II-regulated transcription regulatory genes in adrenal steroidogenesis
    • doi:10.1152/physiolgenomics.00098.2010
    • Romero DG, Gomez-Sanchez EP, Gomez-Sanchez CE. Angiotensin II-regulated transcription regulatory genes in adrenal steroidogenesis. Physiol Genomics (2010) 42A(4):259-66. doi:10.1152/physiolgenomics.00098.2010
    • (2010) Physiol Genomics , vol.42 A , Issue.4 , pp. 259-266
    • Romero, D.G.1    Gomez-Sanchez, E.P.2    Gomez-Sanchez, C.E.3
  • 15
    • 0013900362 scopus 로고
    • Mechanism of glomerulotubular balance. I. Effect of aortic constriction and elevated ureteropelvic pressure on glomerular filtration rate, fractional reabsorption, transit time, and tubular size in the proximal tubule of the rat
    • doi:10.1172/JCI105373
    • Rector FC Jr., Brunner FP, Seldin DW. Mechanism of glomerulotubular balance. I. Effect of aortic constriction and elevated ureteropelvic pressure on glomerular filtration rate, fractional reabsorption, transit time, and tubular size in the proximal tubule of the rat. J Clin Invest (1966) 45(4):590-602. doi:10.1172/JCI105373
    • (1966) J Clin Invest , vol.45 , Issue.4 , pp. 590-602
    • Rector Jr., F.C.1    Brunner, F.P.2    Seldin, D.W.3
  • 16
    • 84872617624 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2, angiotensin-(1-7) and Mas: new players of the renin-angiotensin system
    • doi:10.1530/JOE-12-0341
    • Santos RA, Ferreira AJ, Verano-Braga T, Bader M. Angiotensin-converting enzyme 2, angiotensin-(1-7) and Mas: new players of the renin-angiotensin system. J Endocrinol (2013) 216(2):R1-17. doi:10.1530/JOE-12-0341
    • (2013) J Endocrinol , vol.216 , Issue.2
    • Santos, R.A.1    Ferreira, A.J.2    Verano-Braga, T.3    Bader, M.4
  • 17
    • 77952689893 scopus 로고    scopus 로고
    • The ANG-(1-7)/ACE2/mas axis in the regulation of nephron function
    • doi:10.1152/ajprenal.00110.2010
    • Ferrario CM, Varagic J. The ANG-(1-7)/ACE2/mas axis in the regulation of nephron function. Am J Physiol Renal Physiol (2010) 298(6):F1297-305. doi:10.1152/ajprenal.00110.2010
    • (2010) Am J Physiol Renal Physiol , vol.298 , Issue.6
    • Ferrario, C.M.1    Varagic, J.2
  • 18
    • 84886099600 scopus 로고    scopus 로고
    • Nonclassical renin-angiotensin system and renal function
    • doi:10.1002/cphy.c120002
    • Chappell MC. Nonclassical renin-angiotensin system and renal function. Compr Physiol (2012) 2(4):2733-52. doi:10.1002/cphy.c120002
    • (2012) Compr Physiol , vol.2 , Issue.4 , pp. 2733-2752
    • Chappell, M.C.1
  • 19
    • 84864276934 scopus 로고    scopus 로고
    • Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors
    • doi:10.1161/HYPERTENSIONAHA.112.191403
    • Kemp BA, Bell JF, Rottkamp DM, Howell NL, Shao W, Navar LG, et al. Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors. Hypertension (2012) 60(2):387-95. doi:10.1161/HYPERTENSIONAHA.112.191403
    • (2012) Hypertension , vol.60 , Issue.2 , pp. 387-395
    • Kemp, B.A.1    Bell, J.F.2    Rottkamp, D.M.3    Howell, N.L.4    Shao, W.5    Navar, L.G.6
  • 20
    • 33646511599 scopus 로고    scopus 로고
    • 1 receptor-activated signaling mediates angiotensin IV-induced renal cortical vasoconstriction in rats
    • doi:10.1152/ajprenal.00221.2005
    • 1 receptor-activated signaling mediates angiotensin IV-induced renal cortical vasoconstriction in rats. Am J Physiol Renal Physiol (2006) 290(5):F1024-33. doi:10.1152/ajprenal.00221.2005
    • (2006) Am J Physiol Renal Physiol , vol.290 , Issue.5
    • Li, X.C.1    Campbell, D.J.2    Ohishi, M.3    Yuan, S.4    Zhuo, J.L.5
  • 21
    • 0035966085 scopus 로고    scopus 로고
    • Evidence that the angiotensin IV (AT(4)) receptor is the enzyme insulin-regulated aminopeptidase
    • doi:10.1074/jbc.C100512200
    • Albiston AL, McDowall SG, Matsacos D, Sim P, Clune E, Mustafa T, et al. Evidence that the angiotensin IV (AT(4)) receptor is the enzyme insulin-regulated aminopeptidase. J Biol Chem (2001) 276(52):48623-6. doi:10.1074/jbc.C100512200
    • (2001) J Biol Chem , vol.276 , Issue.52 , pp. 48623-48626
    • Albiston, A.L.1    McDowall, S.G.2    Matsacos, D.3    Sim, P.4    Clune, E.5    Mustafa, T.6
  • 22
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
    • doi:10.1172/JCI0214276
    • Nguyen G, Delarue F, Burckle C, Bouzhir L, Giller T, Sraer JD. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest (2002) 109:1417-27. doi:10.1172/JCI0214276
    • (2002) J Clin Invest , vol.109 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burckle, C.3    Bouzhir, L.4    Giller, T.5    Sraer, J.D.6
  • 23
    • 0037478671 scopus 로고    scopus 로고
    • Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas
    • doi:10.1073/pnas.1432869100
    • Santos RA, Simoes E, Silva AC, Maric C, Silva DM, Machado RP, et al. Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc Natl Acad Sci U S A (2003) 100(14):8258-63. doi:10.1073/pnas.1432869100
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.14 , pp. 8258-8263
    • Santos, R.A.1    Simoes, E.2    Silva, A.C.3    Maric, C.4    Silva, D.M.5    Machado, R.P.6
  • 24
    • 59849116222 scopus 로고    scopus 로고
    • Intrarenal angiotensin III infusion induces natriuresis and angiotensin type 2 receptor translocation in Wistar-Kyoto but not in spontaneously hypertensive rats
    • doi:10.1161/HYPERTENSIONAHA.108.124198
    • Padia SH, Kemp BA, Howell NL, Gildea JJ, Keller SR, Carey RM. Intrarenal angiotensin III infusion induces natriuresis and angiotensin type 2 receptor translocation in Wistar-Kyoto but not in spontaneously hypertensive rats. Hypertension (2009) 53(2):338-43. doi:10.1161/HYPERTENSIONAHA.108.124198
    • (2009) Hypertension , vol.53 , Issue.2 , pp. 338-343
    • Padia, S.H.1    Kemp, B.A.2    Howell, N.L.3    Gildea, J.J.4    Keller, S.R.5    Carey, R.M.6
  • 25
    • 12144256335 scopus 로고    scopus 로고
    • 2 receptor
    • doi:10.1097/00041552-200501000-00011
    • 2 receptor. Curr Opin Nephrol Hypertens (2005) 14(1):67-71. doi:10.1097/00041552-200501000-00011
    • (2005) Curr Opin Nephrol Hypertens , vol.14 , Issue.1 , pp. 67-71
    • Carey, R.M.1
  • 26
    • 0031989144 scopus 로고    scopus 로고
    • Angiotensin IV AT4-receptor system in the rat kidney
    • Handa RK, Krebs LT, Harding JW, Handa SE. Angiotensin IV AT4-receptor system in the rat kidney. Am J Physiol (1998) 274(2 Pt 2):F290-9.
    • (1998) Am J Physiol , vol.274 , Issue.2 PART 2
    • Handa, R.K.1    Krebs, L.T.2    Harding, J.W.3    Handa, S.E.4
  • 27
    • 0032005039 scopus 로고    scopus 로고
    • Autoradiographic identification of kidney angiotensin IV binding sites and angiotensin IV-induced renal cortical blood flow changes in rats
    • doi:10.1016/S0196-9781(97)00291-X
    • Coleman JK, Krebs LT, Hamilton TA, Ong B, Lawrence KA, Sardinia MF, et al. Autoradiographic identification of kidney angiotensin IV binding sites and angiotensin IV-induced renal cortical blood flow changes in rats. Peptides (1998) 19(2):269-77. doi:10.1016/S0196-9781(97)00291-X
    • (1998) Peptides , vol.19 , Issue.2 , pp. 269-277
    • Coleman, J.K.1    Krebs, L.T.2    Hamilton, T.A.3    Ong, B.4    Lawrence, K.A.5    Sardinia, M.F.6
  • 28
    • 0023484592 scopus 로고
    • Effects of angiotensins II and III on glomerulotubular balance in rats
    • doi:10.1111/j.1440-1681.1987.tb01505.x
    • Harris PJ, Zhuo JL, Skinner SL. Effects of angiotensins II and III on glomerulotubular balance in rats. Clin Exp Pharmacol Physiol (1987) 14(6):489-502. doi:10.1111/j.1440-1681.1987.tb01505.x
    • (1987) Clin Exp Pharmacol Physiol , vol.14 , Issue.6 , pp. 489-502
    • Harris, P.J.1    Zhuo, J.L.2    Skinner, S.L.3
  • 30
    • 0028525342 scopus 로고
    • Angiotensin 1-7 has a biphasic effect on fluid absorption in the proximal straight tubule
    • Garcia NH, Garvin JL. Angiotensin 1-7 has a biphasic effect on fluid absorption in the proximal straight tubule. J Am Soc Nephrol (1994) 5(4):1133-8.
    • (1994) J Am Soc Nephrol , vol.5 , Issue.4 , pp. 1133-1138
    • Garcia, N.H.1    Garvin, J.L.2
  • 31
    • 33846996406 scopus 로고    scopus 로고
    • The (pro)renin receptor: pathophysiological roles in cardiovascular and renal pathology
    • doi:10.1097/MNH.0b013e328040bfab
    • Nguyen G. The (pro)renin receptor: pathophysiological roles in cardiovascular and renal pathology. Curr Opin Nephrol Hypertens (2007) 16(2):129-33. doi:10.1097/MNH.0b013e328040bfab
    • (2007) Curr Opin Nephrol Hypertens , vol.16 , Issue.2 , pp. 129-133
    • Nguyen, G.1
  • 32
    • 58149216360 scopus 로고    scopus 로고
    • (Pro)renin receptors: are they biologically relevant?
    • doi:10.1097/MNH.0b013e3283196aaf
    • Danser AH. (Pro)renin receptors: are they biologically relevant? Curr Opin Nephrol Hypertens (2009a) 18(1):74-8. doi:10.1097/MNH.0b013e3283196aaf
    • (2009) Curr Opin Nephrol Hypertens , vol.18 , Issue.1 , pp. 74-78
    • Danser, A.H.1
  • 33
    • 84857820252 scopus 로고    scopus 로고
    • Functional intracellular renin-angiotensin systems: potential for pathophysiology of disease
    • doi:10.1152/ajpregu.00656.2011
    • Carey RM. Functional intracellular renin-angiotensin systems: potential for pathophysiology of disease. Am J Physiol Regul Integr Comp Physiol (2012) 302(5):R479-81. doi:10.1152/ajpregu.00656.2011
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.302 , Issue.5
    • Carey, R.M.1
  • 34
    • 84863230547 scopus 로고    scopus 로고
    • Evidence for a functional intracellular angiotensin system in the proximal tubule of the kidney
    • doi:10.1152/ajpregu.00487.2011
    • Ellis B, Li XC, Miguel-Qin E, Gu V, Zhuo JL. Evidence for a functional intracellular angiotensin system in the proximal tubule of the kidney. Am J Physiol Regul Integr Comp Physiol (2012) 302(5):R494-509. doi:10.1152/ajpregu.00487.2011
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.302 , Issue.5
    • Ellis, B.1    Li, X.C.2    Miguel-Qin, E.3    Gu, V.4    Zhuo, J.L.5
  • 35
    • 84857888402 scopus 로고    scopus 로고
    • Lessons from in vitro studies and a related intracellular angiotensin II transgenic mouse model
    • doi:10.1152/ajpregu.00493.2011
    • Cook JL, Re RN. Lessons from in vitro studies and a related intracellular angiotensin II transgenic mouse model. Am J Physiol Regul Integr Comp Physiol (2012) 302(5):R482-93. doi:10.1152/ajpregu.00493.2011
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.302 , Issue.5
    • Cook, J.L.1    Re, R.N.2
  • 37
  • 38
    • 20144388724 scopus 로고    scopus 로고
    • Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system
    • doi:10.1172/JCI23378
    • Crowley SD, Gurley SB, Oliverio MI, Pazmino AK, Griffiths R, Flannery PJ, et al. Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system. J Clin Invest (2005) 115(4):1092-9. doi:10.1172/JCI23378
    • (2005) J Clin Invest , vol.115 , Issue.4 , pp. 1092-1099
    • Crowley, S.D.1    Gurley, S.B.2    Oliverio, M.I.3    Pazmino, A.K.4    Griffiths, R.5    Flannery, P.J.6
  • 39
    • 84890022318 scopus 로고    scopus 로고
    • The intrarenal renin-angiotensin system: does it exist? Implications from a recent study in renal angiotensin-converting enzyme knockout mice
    • doi:10.1093/ndt/gft333
    • Lu X, Roksnoer LC, Danser AH. The intrarenal renin-angiotensin system: does it exist? Implications from a recent study in renal angiotensin-converting enzyme knockout mice. Nephrol Dial Transplant (2013). doi:10.1093/ndt/gft333
    • (2013) Nephrol Dial Transplant
    • Lu, X.1    Roksnoer, L.C.2    Danser, A.H.3
  • 40
    • 79953743181 scopus 로고    scopus 로고
    • AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure
    • doi:10.1016/j.cmet.2011.03.001
    • Gurley SB, Riquier-Brison AD, Schnermann J, Sparks MA, Allen AM, Haase VH, et al. AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure. Cell Metab (2011) 13(4):469-75. doi:10.1016/j.cmet.2011.03.001
    • (2011) Cell Metab , vol.13 , Issue.4 , pp. 469-475
    • Gurley, S.B.1    Riquier-Brison, A.D.2    Schnermann, J.3    Sparks, M.A.4    Allen, A.M.5    Haase, V.H.6
  • 43
    • 34748859681 scopus 로고    scopus 로고
    • The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease
    • doi:10.1124/pr.59.3.3
    • Kobori H, Nangaku M, Navar LG, Nishiyama A. The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease. Pharmacol Rev (2007) 59(3):251-87. doi:10.1124/pr.59.3.3
    • (2007) Pharmacol Rev , vol.59 , Issue.3 , pp. 251-287
    • Kobori, H.1    Nangaku, M.2    Navar, L.G.3    Nishiyama, A.4
  • 44
    • 79953238880 scopus 로고    scopus 로고
    • Intratubular renin-angiotensin system in hypertension
    • doi:10.1161/HYPERTENSIONAHA.110.163519
    • Navar LG, Kobori H, Prieto MC, Gonzalez-Villalobos RA. Intratubular renin-angiotensin system in hypertension. Hypertension (2011) 57(3):355-62. doi:10.1161/HYPERTENSIONAHA.110.163519
    • (2011) Hypertension , vol.57 , Issue.3 , pp. 355-362
    • Navar, L.G.1    Kobori, H.2    Prieto, M.C.3    Gonzalez-Villalobos, R.A.4
  • 45
    • 79960290029 scopus 로고    scopus 로고
    • New insights and perspectives on intrarenal renin-angiotensin system: focus on intracrine/intracellular angiotensin II
    • doi:10.1016/j.peptides.2011.05.012
    • Zhuo JL, Li XC. New insights and perspectives on intrarenal renin-angiotensin system: focus on intracrine/intracellular angiotensin II. Peptides (2011) 32(7):1551-65. doi:10.1016/j.peptides.2011.05.012
    • (2011) Peptides , vol.32 , Issue.7 , pp. 1551-1565
    • Zhuo, J.L.1    Li, X.C.2
  • 46
    • 0036150620 scopus 로고    scopus 로고
    • Renal interstitial fluid concentrations of angiotensins I and II in anesthetized rats
    • doi:10.1161/hy0102.100536
    • Nishiyama A, Seth DM, Navar LG. Renal interstitial fluid concentrations of angiotensins I and II in anesthetized rats. Hypertension (2002) 39(1):129-34. doi:10.1161/hy0102.100536
    • (2002) Hypertension , vol.39 , Issue.1 , pp. 129-134
    • Nishiyama, A.1    Seth, D.M.2    Navar, L.G.3
  • 47
    • 0029044090 scopus 로고
    • Renal interstitial fluid angiotensin. Modulation by anesthesia, epinephrine, sodium depletion, and renin inhibition
    • doi:10.1161/01.HYP.25.5.1021
    • Siragy HM, Howell NL, Ragsdale NV, Carey RM. Renal interstitial fluid angiotensin. Modulation by anesthesia, epinephrine, sodium depletion, and renin inhibition. Hypertension (1995) 25(5):1021-4. doi:10.1161/01.HYP.25.5.1021
    • (1995) Hypertension , vol.25 , Issue.5 , pp. 1021-1024
    • Siragy, H.M.1    Howell, N.L.2    Ragsdale, N.V.3    Carey, R.M.4
  • 49
    • 33846241330 scopus 로고    scopus 로고
    • Angiotensin metabolism in renal proximal tubules, urine, and serum of sheep: evidence for ACE2-dependent processing of angiotensin II
    • doi:10.1152/ajprenal.00139.2006
    • Shaltout HA, Westwood BM, Averill DB, Ferrario CM, Figueroa JP, Diz DI, et al. Angiotensin metabolism in renal proximal tubules, urine, and serum of sheep: evidence for ACE2-dependent processing of angiotensin II. Am J Physiol Renal Physiol (2007) 292(1):F82-91. doi:10.1152/ajprenal.00139.2006
    • (2007) Am J Physiol Renal Physiol , vol.292 , Issue.1
    • Shaltout, H.A.1    Westwood, B.M.2    Averill, D.B.3    Ferrario, C.M.4    Figueroa, J.P.5    Diz, D.I.6
  • 50
    • 0027157347 scopus 로고
    • Proximal tubular secretion of angiotensin II in rats
    • Braam B, Mitchell KD, Fox J, Navar LG. Proximal tubular secretion of angiotensin II in rats. Am J Physiol (1993) 264(5 Pt 2):F891-8.
    • (1993) Am J Physiol , vol.264 , Issue.5 PART 2
    • Braam, B.1    Mitchell, K.D.2    Fox, J.3    Navar, L.G.4
  • 51
    • 0028524896 scopus 로고
    • Tubular fluid concentrations and kidney contents of angiotensins I and II in anesthetized rats
    • Navar LG, Lewis L, Hymel A, Braam B, Mitchell KD. Tubular fluid concentrations and kidney contents of angiotensins I and II in anesthetized rats. J Am Soc Nephrol (1994) 5(4):1153-8.
    • (1994) J Am Soc Nephrol , vol.5 , Issue.4 , pp. 1153-1158
    • Navar, L.G.1    Lewis, L.2    Hymel, A.3    Braam, B.4    Mitchell, K.D.5
  • 52
    • 0032829061 scopus 로고    scopus 로고
    • Renal endosomes contain angiotensin peptides, converting enzyme, and AT1A receptors
    • Imig JD, Navar GL, Zou LX, O'Reilly KC, Allen PL, Kaysen JH, et al. Renal endosomes contain angiotensin peptides, converting enzyme, and AT1A receptors. Am J Physiol (1999) 277(2 Pt 2):F303-11.
    • (1999) Am J Physiol , vol.277 , Issue.2 PART 2
    • Imig, J.D.1    Navar, G.L.2    Zou, L.X.3    O'Reilly, K.C.4    Allen, P.L.5    Kaysen, J.H.6
  • 53
    • 0029926379 scopus 로고    scopus 로고
    • Renal accumulation of circulating angiotensin II in angiotensin II-infused rats
    • doi:10.1161/01.HYP.27.3.658
    • Zou LX, Hymel A, Imig JD, Navar LG. Renal accumulation of circulating angiotensin II in angiotensin II-infused rats. Hypertension (1996) 27(3 Pt 2):658-62. doi:10.1161/01.HYP.27.3.658
    • (1996) Hypertension , vol.27 , Issue.3 PART 2 , pp. 658-662
    • Zou, L.X.1    Hymel, A.2    Imig, J.D.3    Navar, L.G.4
  • 54
    • 0031839482 scopus 로고    scopus 로고
    • Renal uptake of circulating angiotensin II in Val5-angiotensin II infused rats is mediated by AT1 receptor
    • doi:10.1016/S0895-7061(97)00410-X
    • Zou LX, Imig JD, Hymel A, Navar LG. Renal uptake of circulating angiotensin II in Val5-angiotensin II infused rats is mediated by AT1 receptor. Am J Hypertens (1998) 11(5):570-8. doi:10.1016/S0895-7061(97)00410-X
    • (1998) Am J Hypertens , vol.11 , Issue.5 , pp. 570-578
    • Zou, L.X.1    Imig, J.D.2    Hymel, A.3    Navar, L.G.4
  • 55
    • 0035190220 scopus 로고    scopus 로고
    • Intrarenal angiotensin II: interstitial and cellular levels and site of production
    • doi:10.1046/j.1523-1755.2001.00049.x
    • van Kats JP, Schalekamp MA, Verdouw PD, Duncker DJ, Danser AH. Intrarenal angiotensin II: interstitial and cellular levels and site of production. Kidney Int (2001) 60(6):2311-7. doi:10.1046/j.1523-1755.2001.00049.x
    • (2001) Kidney Int , vol.60 , Issue.6 , pp. 2311-2317
    • van Kats, J.P.1    Schalekamp, M.A.2    Verdouw, P.D.3    Duncker, D.J.4    Danser, A.H.5
  • 56
    • 0035066863 scopus 로고    scopus 로고
    • Subcellular localization of angiotensin II in kidney and adrenal
    • doi:10.1097/00004872-200103001-00010
    • van Kats JP, van Meegen JR, Verdouw PD, Duncker DJ, Schalekamp MA, Danser AH. Subcellular localization of angiotensin II in kidney and adrenal. J Hypertens (2001) 19(3 Pt 2):583-9. doi:10.1097/00004872-200103001-00010
    • (2001) J Hypertens , vol.19 , Issue.3 PART 2 , pp. 583-589
    • van Kats, J.P.1    van Meegen, J.R.2    Verdouw, P.D.3    Duncker, D.J.4    Schalekamp, M.A.5    Danser, A.H.6
  • 57
    • 34548385407 scopus 로고    scopus 로고
    • 1a receptors attenuates intracellular accumulation of angiotensin II in the kidney of AT1a receptor-deficient mice
    • doi:10.1152/ajprenal.00489.2006
    • 1a receptors attenuates intracellular accumulation of angiotensin II in the kidney of AT1a receptor-deficient mice. Am J Physiol Renal Physiol (2007) 293:F586-93. doi:10.1152/ajprenal.00489.2006
    • (2007) Am J Physiol Renal Physiol , vol.293
    • Li, X.C.1    Navar, L.G.2    Shao, Y.3    Zhuo, J.L.4
  • 58
    • 38849099032 scopus 로고    scopus 로고
    • 1a receptor-mediated intracellular uptake of [125I]-Val5-angiotensin II in the kidneys and adrenal glands of AT1a receptor-deficient mice
    • doi:10.1152/ajprenal.00398.2007
    • 1a receptor-mediated intracellular uptake of [125I]-Val5-angiotensin II in the kidneys and adrenal glands of AT1a receptor-deficient mice. Am J Physiol Renal Physiol (2008a) 294:F293-302. doi:10.1152/ajprenal.00398.2007
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Li, X.C.1    Zhuo, J.L.2
  • 59
    • 0034527806 scopus 로고    scopus 로고
    • Receptor/beta-arrestin complex formation and the differential trafficking and resensitization of beta2-adrenergic and angiotensin II type 1A receptors
    • doi:10.1210/me.14.12.2040
    • Anborgh PH, Seachrist JL, Dale LB, Ferguson SS. Receptor/beta-arrestin complex formation and the differential trafficking and resensitization of beta2-adrenergic and angiotensin II type 1A receptors. Mol Endocrinol (2000) 14(12):2040-53. doi:10.1210/me.14.12.2040
    • (2000) Mol Endocrinol , vol.14 , Issue.12 , pp. 2040-2053
    • Anborgh, P.H.1    Seachrist, J.L.2    Dale, L.B.3    Ferguson, S.S.4
  • 60
    • 0035101820 scopus 로고    scopus 로고
    • Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling
    • Ferguson SS. Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol Rev (2001) 53(1):1-24.
    • (2001) Pharmacol Rev , vol.53 , Issue.1 , pp. 1-24
    • Ferguson, S.S.1
  • 61
    • 0031446688 scopus 로고    scopus 로고
    • 2 receptors: evidence for selective sorting of receptor and ligand
    • doi:10.1210/me.11.9.1266
    • 2 receptors: evidence for selective sorting of receptor and ligand. Mol Endocrinol (1997) 11(9):1266-77. doi:10.1210/me.11.9.1266
    • (1997) Mol Endocrinol , vol.11 , Issue.9 , pp. 1266-1277
    • Hein, L.1    Meinel, L.2    Pratt, R.E.3    Dzau, V.J.4    Kobilka, B.K.5
  • 62
    • 0034725712 scopus 로고    scopus 로고
    • 1 angiotensin receptor internalization
    • doi:10.1016/S0167-0115(00)00137-3
    • 1 angiotensin receptor internalization. Regul Pept (2000) 91(1-3):29-44. doi:10.1016/S0167-0115(00)00137-3
    • (2000) Regul Pept , vol.91 , Issue.1-3 , pp. 29-44
    • Hunyady, L.1    Catt, K.J.2    Clark, A.J.3    Gaborik, Z.4
  • 63
    • 77952415656 scopus 로고    scopus 로고
    • Beyond desensitization: physiological relevance of arrestin-dependent signaling
    • doi:10.1124/pr.109.002436
    • Luttrell LM, Gesty-Palmer D. Beyond desensitization: physiological relevance of arrestin-dependent signaling. Pharmacol Rev (2010) 62(2):305-30. doi:10.1124/pr.109.002436
    • (2010) Pharmacol Rev , vol.62 , Issue.2 , pp. 305-330
    • Luttrell, L.M.1    Gesty-Palmer, D.2
  • 65
    • 0142042336 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor-mediated augmentation of renal interstitial fluid angiotensin II in angiotensin II-induced hypertension
    • doi:10.1097/00004872-200310000-00017
    • Nishiyama A, Seth DM, Navar LG. Angiotensin II type 1 receptor-mediated augmentation of renal interstitial fluid angiotensin II in angiotensin II-induced hypertension. J Hypertens (2003) 21(10):1897-903. doi:10.1097/00004872-200310000-00017
    • (2003) J Hypertens , vol.21 , Issue.10 , pp. 1897-1903
    • Nishiyama, A.1    Seth, D.M.2    Navar, L.G.3
  • 67
    • 0035715157 scopus 로고    scopus 로고
    • Enhancement of angiotensinogen expression in angiotensin II-dependent hypertension
    • doi:10.1161/01.HYP.37.5.1329
    • Kobori H, Harrison-Bernard LM, Navar LG. Enhancement of angiotensinogen expression in angiotensin II-dependent hypertension. Hypertension (2001) 37(5):1329-35. doi:10.1161/01.HYP.37.5.1329
    • (2001) Hypertension , vol.37 , Issue.5 , pp. 1329-1335
    • Kobori, H.1    Harrison-Bernard, L.M.2    Navar, L.G.3
  • 68
    • 23944471832 scopus 로고    scopus 로고
    • AT1 receptor-mediated enhancement of collecting duct renin in angiotensin II-dependent hypertensive rats
    • doi:10.1152/ajprenal.00462.2004
    • Prieto-Carrasquero MC, Kobori H, Ozawa Y, Gutierrez A, Seth D, Navar LG. AT1 receptor-mediated enhancement of collecting duct renin in angiotensin II-dependent hypertensive rats. Am J Physiol Renal Physiol (2005) 289(3):F632-7. doi:10.1152/ajprenal.00462.2004
    • (2005) Am J Physiol Renal Physiol , vol.289 , Issue.3
    • Prieto-Carrasquero, M.C.1    Kobori, H.2    Ozawa, Y.3    Gutierrez, A.4    Seth, D.5    Navar, L.G.6
  • 69
    • 79551532780 scopus 로고    scopus 로고
    • Enhancement of renin and prorenin receptor in collecting duct of Cyp1a1-Ren2 rats may contribute to development and progression of malignant hypertension
    • doi:10.1152/ajprenal.00433.2010
    • Prieto MC, Williams DE, Liu L, Kavanagh KL, Mullins JJ, Mitchell KD. Enhancement of renin and prorenin receptor in collecting duct of Cyp1a1-Ren2 rats may contribute to development and progression of malignant hypertension. Am J Physiol Renal Physiol (2011) 300(2):F581-8. doi:10.1152/ajprenal.00433.2010
    • (2011) Am J Physiol Renal Physiol , vol.300 , Issue.2
    • Prieto, M.C.1    Williams, D.E.2    Liu, L.3    Kavanagh, K.L.4    Mullins, J.J.5    Mitchell, K.D.6
  • 70
    • 82755191651 scopus 로고    scopus 로고
    • Increased renin excretion associated with augmented urinary angiotensin (Ang) II levels in chronic angiotensin II-infused hypertensive rats
    • doi:10.1152/ajprenal.00339.2011
    • Liu L, Gonzalez AA, McCormack M, Seth DM, Kobori H, Navar LG, et al. Increased renin excretion associated with augmented urinary angiotensin (Ang) II levels in chronic angiotensin II-infused hypertensive rats. Am J Physiol Renal Physiol (2011) 301(6):F1195-201. doi:10.1152/ajprenal.00339.2011
    • (2011) Am J Physiol Renal Physiol , vol.301 , Issue.6
    • Liu, L.1    Gonzalez, A.A.2    McCormack, M.3    Seth, D.M.4    Kobori, H.5    Navar, L.G.6
  • 71
    • 82755177500 scopus 로고    scopus 로고
    • Augmented intratubular renin and prorenin expression in the medullary collecting ducts of the kidney as a novel mechanism of angiotensin II-induced hypertension
    • doi:10.1152/ajprenal.00555.2011
    • Zhuo JL. Augmented intratubular renin and prorenin expression in the medullary collecting ducts of the kidney as a novel mechanism of angiotensin II-induced hypertension. Am J Physiol Renal Physiol (2011) 301(6):F1193-4. doi:10.1152/ajprenal.00555.2011
    • (2011) Am J Physiol Renal Physiol , vol.301 , Issue.6
    • Zhuo, J.L.1
  • 72
    • 84875205122 scopus 로고    scopus 로고
    • Prorenin receptor in distal nephron segments of 2-kidney, 1-clip Goldblatt hypertensive rats
    • Prieto MC, Botros FT, Kavanagh K, Navar LG. Prorenin receptor in distal nephron segments of 2-kidney, 1-clip Goldblatt hypertensive rats. Ochsner J (2013) 13(1):26-32.
    • (2013) Ochsner J , vol.13 , Issue.1 , pp. 26-32
    • Prieto, M.C.1    Botros, F.T.2    Kavanagh, K.3    Navar, L.G.4
  • 73
    • 84863503716 scopus 로고    scopus 로고
    • Liver angiotensinogen is the primary source of renal angiotensin II
    • doi:10.1681/ASN.2011121159
    • Matsusaka T, Niimura F, Shimizu A, Pastan I, Saito A, Kobori H, et al. Liver angiotensinogen is the primary source of renal angiotensin II. J Am Soc Nephrol (2012) 23(7):1181-9. doi:10.1681/ASN.2011121159
    • (2012) J Am Soc Nephrol , vol.23 , Issue.7 , pp. 1181-1189
    • Matsusaka, T.1    Niimura, F.2    Shimizu, A.3    Pastan, I.4    Saito, A.5    Kobori, H.6
  • 74
    • 84863514954 scopus 로고    scopus 로고
    • The increasing complexity of the intratubular Renin-Angiotensin system
    • doi:10.1681/ASN.2012050493
    • Navar LG, Satou R, Gonzalez-Villalobos RA. The increasing complexity of the intratubular Renin-Angiotensin system. J Am Soc Nephrol (2012) 23(7):1130-2. doi:10.1681/ASN.2012050493
    • (2012) J Am Soc Nephrol , vol.23 , Issue.7 , pp. 1130-1132
    • Navar, L.G.1    Satou, R.2    Gonzalez-Villalobos, R.A.3
  • 75
    • 79952340670 scopus 로고    scopus 로고
    • Intrarenal angiotensin-converting enzyme induces hypertension in response to angiotensin I infusion
    • doi:10.1681/ASN.2010060624
    • Gonzalez-Villalobos RA, Billet S, Kim C, Satou R, Fuchs S, Bernstein KE, et al. Intrarenal angiotensin-converting enzyme induces hypertension in response to angiotensin I infusion. J Am Soc Nephrol (2011) 22(3):449-59. doi:10.1681/ASN.2010060624
    • (2011) J Am Soc Nephrol , vol.22 , Issue.3 , pp. 449-459
    • Gonzalez-Villalobos, R.A.1    Billet, S.2    Kim, C.3    Satou, R.4    Fuchs, S.5    Bernstein, K.E.6
  • 76
    • 81255195551 scopus 로고    scopus 로고
    • Under pressure: the search for the essential mechanisms of hypertension
    • doi:10.1038/nm.2541
    • Coffman TM. Under pressure: the search for the essential mechanisms of hypertension. Nat Med (2011) 17(11):1402-9. doi:10.1038/nm.2541
    • (2011) Nat Med , vol.17 , Issue.11 , pp. 1402-1409
    • Coffman, T.M.1
  • 77
    • 79955760915 scopus 로고    scopus 로고
    • Intrarenal transfer of an intracellular cyan fluorescent fusion of angiotensin II selectively in proximal tubules increases blood pressure in rats and mice
    • doi:10.1152/ajprenal.00329.2010
    • Li XC, Cook JL, Rubera I, Tauc M, Zhang F, Zhuo JL. Intrarenal transfer of an intracellular cyan fluorescent fusion of angiotensin II selectively in proximal tubules increases blood pressure in rats and mice. Am J Physiol Renal Physiol (2011) 300:F1076-88. doi:10.1152/ajprenal.00329.2010
    • (2011) Am J Physiol Renal Physiol , vol.300
    • Li, X.C.1    Cook, J.L.2    Rubera, I.3    Tauc, M.4    Zhang, F.5    Zhuo, J.L.6
  • 78
    • 1842292171 scopus 로고    scopus 로고
    • The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice
    • doi:10.1172/JCI119419
    • Esther CR, Marino EM, Howard TE, Machaud A, Corvol P, Capecchi MR, et al. The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice. J Clin Invest (1997) 99:2375-85. doi:10.1172/JCI119419
    • (1997) J Clin Invest , vol.99 , pp. 2375-2385
    • Esther, C.R.1    Marino, E.M.2    Howard, T.E.3    Machaud, A.4    Corvol, P.5    Capecchi, M.R.6
  • 79
    • 0037059464 scopus 로고    scopus 로고
    • Mice lacking endothelial angiotensin-converting enzyme have a normal blood pressure
    • doi:10.1161/hh0102.102360
    • Cole J, Quach DL, Sundaram K, Corvol P, Capecchi MR, Bernstein KE. Mice lacking endothelial angiotensin-converting enzyme have a normal blood pressure. Circ Res (2002) 90(1):87-92. doi:10.1161/hh0102.102360
    • (2002) Circ Res , vol.90 , Issue.1 , pp. 87-92
    • Cole, J.1    Quach, D.L.2    Sundaram, K.3    Corvol, P.4    Capecchi, M.R.5    Bernstein, K.E.6
  • 80
    • 14044254866 scopus 로고    scopus 로고
    • Micropuncture determination of nephron function in mice without tissue angiotensin-converting enzyme
    • doi:10.1152/ajprenal.00297.2004
    • Hashimoto S, Adams JW, Bernstein KE, Schnermann J. Micropuncture determination of nephron function in mice without tissue angiotensin-converting enzyme. Am J Physiol Renal Physiol (2005) 288(3):F445-52. doi:10.1152/ajprenal.00297.2004
    • (2005) Am J Physiol Renal Physiol , vol.288 , Issue.3
    • Hashimoto, S.1    Adams, J.W.2    Bernstein, K.E.3    Schnermann, J.4
  • 81
    • 33645900598 scopus 로고    scopus 로고
    • Nephron function in transgenic mice with selective vascular or tubular expression of Angiotensin-converting enzyme
    • doi:10.1681/ASN.2005020151
    • Kessler SP, Hashimoto S, Senanayake PS, Gaughan C, Sen GC, Schnermann J. Nephron function in transgenic mice with selective vascular or tubular expression of Angiotensin-converting enzyme. J Am Soc Nephrol (2005) 16(12):3535-42. doi:10.1681/ASN.2005020151
    • (2005) J Am Soc Nephrol , vol.16 , Issue.12 , pp. 3535-3542
    • Kessler, S.P.1    Hashimoto, S.2    Senanayake, P.S.3    Gaughan, C.4    Sen, G.C.5    Schnermann, J.6
  • 82
    • 0038756637 scopus 로고    scopus 로고
    • Maintenance of normal blood pressure and renal functions are independent effects of angiotensin-converting enzyme
    • doi:10.1074/jbc.M3023472000
    • Kessler SP, deS SP, Scheidemantel TS, Gomos JB, Rowe TM, Sen GC. Maintenance of normal blood pressure and renal functions are independent effects of angiotensin-converting enzyme. J Biol Chem (2003) 278(23):21105-12. doi:10.1074/jbc.M3023472000
    • (2003) J Biol Chem , vol.278 , Issue.23 , pp. 21105-21112
    • Kessler, S.P.1    deS, S.P.2    Scheidemantel, T.S.3    Gomos, J.B.4    Rowe, T.M.5    Sen, G.C.6
  • 83
    • 84877111817 scopus 로고    scopus 로고
    • Where hypertension happens
    • doi:10.1172/JCI69296
    • Reudelhuber TL. Where hypertension happens. J Clin Invest (2013) 123(5):1934-6. doi:10.1172/JCI69296
    • (2013) J Clin Invest , vol.123 , Issue.5 , pp. 1934-1936
    • Reudelhuber, T.L.1
  • 84
    • 0029797409 scopus 로고    scopus 로고
    • Receptor-mediated intrarenal angiotensin II augmentation in angiotensin II-infused rats
    • doi:10.1161/01.HYP.28.4.669
    • Zou LX, Imig JD, von Thun AM, Hymel A, Ono H, Navar LG. Receptor-mediated intrarenal angiotensin II augmentation in angiotensin II-infused rats. Hypertension (1996) 28(4):669-77. doi:10.1161/01.HYP.28.4.669
    • (1996) Hypertension , vol.28 , Issue.4 , pp. 669-677
    • Zou, L.X.1    Imig, J.D.2    von Thun, A.M.3    Hymel, A.4    Ono, H.5    Navar, L.G.6
  • 86
    • 0031034312 scopus 로고    scopus 로고
    • Angiotensin-(1-7) augments bradykinin-induced vasodilation by competing with ACE and releasing nitric oxide
    • doi:10.1161/01.HYP.29.1.394
    • Li P, Chappell MC, Ferrario CM, Brosnihan KB. Angiotensin-(1-7) augments bradykinin-induced vasodilation by competing with ACE and releasing nitric oxide. Hypertension (1997) 29(1 Pt 2):394-400. doi:10.1161/01.HYP.29.1.394
    • (1997) Hypertension , vol.29 , Issue.1 PART 2 , pp. 394-400
    • Li, P.1    Chappell, M.C.2    Ferrario, C.M.3    Brosnihan, K.B.4
  • 88
    • 0025942209 scopus 로고
    • Angiotensin-(1-7): a new hormone of the angiotensin system
    • III126-III133,doi:10.1161/01.HYP.18.5_Suppl.III126
    • Ferrario CM, Brosnihan KB, Diz DI, Jaiswal N, Khosla MC, Milsted A, et al. Angiotensin-(1-7): a new hormone of the angiotensin system. Hypertension (1991) 18(5 Suppl):III126-33. doi:10.1161/01.HYP.18.5_Suppl.III126
    • (1991) Hypertension , vol.18 , Issue.5 SUPPL.
    • Ferrario, C.M.1    Brosnihan, K.B.2    Diz, D.I.3    Jaiswal, N.4    Khosla, M.C.5    Milsted, A.6
  • 89
    • 0001591377 scopus 로고
    • Structural-activity relationship in angiotensin II analogs
    • Page IH, Bumpus FM editors. Heidelberg: Springer-Verlag Berlin.
    • Khosla MC, Smeby RR, Bumps FM. Structural-activity relationship in angiotensin II analogs. In: Page IH, Bumpus FM editors. Angiotensin. Handbook of Experimental Pharmacology XXXVII. Heidelberg: Springer-Verlag Berlin (1974). p. 126-61.
    • (1974) Angiotensin. Handbook of Experimental Pharmacology XXXVII , pp. 126-161
    • Khosla, M.C.1    Smeby, R.R.2    Bumps, F.M.3
  • 90
    • 34250794999 scopus 로고    scopus 로고
    • Expression of an angiotensin-(1-7)-producing fusion protein in rats induced marked changes in regional vascular resistance
    • doi:10.1152/ajpheart.01245.2006
    • Botelho-Santos GA, Sampaio WO, Reudelhuber TL, Bader M, Campagnole-Santos MJ, Santos RA. Expression of an angiotensin-(1-7)-producing fusion protein in rats induced marked changes in regional vascular resistance. Am J Physiol Heart Circ Physiol (2007) 292(5):H2485-90. doi:10.1152/ajpheart.01245.2006
    • (2007) Am J Physiol Heart Circ Physiol , vol.292 , Issue.5
    • Botelho-Santos, G.A.1    Sampaio, W.O.2    Reudelhuber, T.L.3    Bader, M.4    Campagnole-Santos, M.J.5    Santos, R.A.6
  • 91
    • 33751503376 scopus 로고    scopus 로고
    • Renal function in transgenic rats expressing an angiotensin-(1-7)-producing fusion protein
    • doi:10.1016/j.regpep.2006.06.005
    • Ferreira AJ, Pinheiro SV, Castro CH, Silva GA, Silva AC, Almeida AP, et al. Renal function in transgenic rats expressing an angiotensin-(1-7)-producing fusion protein. Regul Pept (2006) 137(3):128-33. doi:10.1016/j.regpep.2006.06.005
    • (2006) Regul Pept , vol.137 , Issue.3 , pp. 128-133
    • Ferreira, A.J.1    Pinheiro, S.V.2    Castro, C.H.3    Silva, G.A.4    Silva, A.C.5    Almeida, A.P.6
  • 92
    • 58149352445 scopus 로고    scopus 로고
    • Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart
    • doi:10.1161/CIRCRESAHA.108.184911
    • Mercure C, Yogi A, Callera GE, Aranha AB, Bader M, Ferreira AJ, et al. Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart. Circ Res (2008) 103(11):1319-26. doi:10.1161/CIRCRESAHA.108.184911
    • (2008) Circ Res , vol.103 , Issue.11 , pp. 1319-1326
    • Mercure, C.1    Yogi, A.2    Callera, G.E.3    Aranha, A.B.4    Bader, M.5    Ferreira, A.J.6
  • 93
    • 0026605307 scopus 로고
    • In vivo metabolism of angiotensin I by neutral endopeptidase (EC 3.4.24.11) in spontaneously hypertensive rats
    • doi:10.1161/01.HYP.19.6.692
    • Yamamoto K, Chappell MC, Brosnihan KB, Ferrario CM. In vivo metabolism of angiotensin I by neutral endopeptidase (EC 3.4.24.11) in spontaneously hypertensive rats. Hypertension (1992) 19(6 Pt 2):692-6. doi:10.1161/01.HYP.19.6.692
    • (1992) Hypertension , vol.19 , Issue.6 PART 2 , pp. 692-696
    • Yamamoto, K.1    Chappell, M.C.2    Brosnihan, K.B.3    Ferrario, C.M.4
  • 94
    • 1642460617 scopus 로고    scopus 로고
    • Depletion of tissue angiotensin-converting enzyme differentially influences the intrarenal and urinary expression of angiotensin peptides
    • doi:10.1161/01.HYP.0000121462.27393.f6
    • Modrall JG, Sadjadi J, Brosnihan KB, Gallagher PE, Yu CH, Kramer GL, et al. Depletion of tissue angiotensin-converting enzyme differentially influences the intrarenal and urinary expression of angiotensin peptides. Hypertension (2004) 43(4):849-53. doi:10.1161/01.HYP.0000121462.27393.f6
    • (2004) Hypertension , vol.43 , Issue.4 , pp. 849-853
    • Modrall, J.G.1    Sadjadi, J.2    Brosnihan, K.B.3    Gallagher, P.E.4    Yu, C.H.5    Kramer, G.L.6
  • 97
    • 0022500358 scopus 로고
    • Regulation of glomerular filtration rate and sodium excretion by angiotensin II
    • Hall JE. Regulation of glomerular filtration rate and sodium excretion by angiotensin II. Fed Proc (1986) 45(5):1431-7.
    • (1986) Fed Proc , vol.45 , Issue.5 , pp. 1431-1437
    • Hall, J.E.1
  • 98
    • 84890266570 scopus 로고    scopus 로고
    • Proximal nephron
    • doi:10.1002/cphy.c110061
    • Zhuo JL, Li XC. Proximal nephron. Compr Physiol (2013) 3(3):1079-123. doi:10.1002/cphy.c110061
    • (2013) Compr Physiol , vol.3 , Issue.3 , pp. 1079-1123
    • Zhuo, J.L.1    Li, X.C.2
  • 99
    • 0030810845 scopus 로고    scopus 로고
    • Counterregulatory actions of angiotensin-(1-7)
    • doi:10.1161/01.HYP.30.3.535
    • Ferrario CM, Chappell MC, Tallant EA, Brosnihan KB, Diz DI. Counterregulatory actions of angiotensin-(1-7). Hypertension (1997) 30(3 Pt 2):535-41. doi:10.1161/01.HYP.30.3.535
    • (1997) Hypertension , vol.30 , Issue.3 PART 2 , pp. 535-541
    • Ferrario, C.M.1    Chappell, M.C.2    Tallant, E.A.3    Brosnihan, K.B.4    Diz, D.I.5
  • 102
    • 84878667060 scopus 로고    scopus 로고
    • Dose-dependent effects of angiotensin-(1-7) on the NHE3 exchanger and [Ca(2+)](i) in in vivo proximal tubules
    • doi:10.1152/ajprenal.00401.2012
    • Castelo-Branco RC, Leite-Delova DC, de Mello-Aires M. Dose-dependent effects of angiotensin-(1-7) on the NHE3 exchanger and [Ca(2+)](i) in in vivo proximal tubules. Am J Physiol Renal Physiol (2013) 304(10):F1258-65. doi:10.1152/ajprenal.00401.2012
    • (2013) Am J Physiol Renal Physiol , vol.304 , Issue.10
    • Castelo-Branco, R.C.1    Leite-Delova, D.C.2    de Mello-Aires, M.3
  • 104
    • 3042723695 scopus 로고    scopus 로고
    • Expression of an angiotensin-(1-7)-producing fusion protein produces cardioprotective effects in rats
    • doi:10.1152/physiolgenomics.00227.2003
    • Santos RA, Ferreira AJ, Nadu AP, Braga AN, de Almeida AP, Campagnole-Santos MJ, et al. Expression of an angiotensin-(1-7)-producing fusion protein produces cardioprotective effects in rats. Physiol Genomics (2004) 17(3):292-9. doi:10.1152/physiolgenomics.00227.2003
    • (2004) Physiol Genomics , vol.17 , Issue.3 , pp. 292-299
    • Santos, R.A.1    Ferreira, A.J.2    Nadu, A.P.3    Braga, A.N.4    de Almeida, A.P.5    Campagnole-Santos, M.J.6
  • 105
    • 55949126600 scopus 로고    scopus 로고
    • Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function
    • doi:10.1161/HYPERTENSIONAHA.108.114322
    • Rentzsch B, Todiras M, Iliescu R, Popova E, Campos LA, Oliveira ML, et al. Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function. Hypertension (2008) 52(5):967-73. doi:10.1161/HYPERTENSIONAHA.108.114322
    • (2008) Hypertension , vol.52 , Issue.5 , pp. 967-973
    • Rentzsch, B.1    Todiras, M.2    Iliescu, R.3    Popova, E.4    Campos, L.A.5    Oliveira, M.L.6
  • 106
    • 78651497653 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme (ACE) 2 overexpression ameliorates glomerular injury in a rat model of diabetic nephropathy: a comparison with ACE inhibition
    • doi:10.2119/molmed.2010.00111
    • Liu CX, Hu Q, Wang Y, Zhang W, Ma ZY, Feng JB, et al. Angiotensin-converting enzyme (ACE) 2 overexpression ameliorates glomerular injury in a rat model of diabetic nephropathy: a comparison with ACE inhibition. Mol Med (2011) 17(1-2):59-69. doi:10.2119/molmed.2010.00111
    • (2011) Mol Med , vol.17 , Issue.1-2 , pp. 59-69
    • Liu, C.X.1    Hu, Q.2    Wang, Y.3    Zhang, W.4    Ma, Z.Y.5    Feng, J.B.6
  • 107
    • 84863802059 scopus 로고    scopus 로고
    • Podocyte-specific overexpression of human angiotensin-converting enzyme 2 attenuates diabetic nephropathy in mice
    • doi:10.1038/ki.2012.83
    • Nadarajah R, Milagres R, Dilauro M, Gutsol A, Xiao F, Zimpelmann J, et al. Podocyte-specific overexpression of human angiotensin-converting enzyme 2 attenuates diabetic nephropathy in mice. Kidney Int (2012) 82(3):292-303. doi:10.1038/ki.2012.83
    • (2012) Kidney Int , vol.82 , Issue.3 , pp. 292-303
    • Nadarajah, R.1    Milagres, R.2    Dilauro, M.3    Gutsol, A.4    Xiao, F.5    Zimpelmann, J.6
  • 108
    • 34047193877 scopus 로고    scopus 로고
    • Overexpression of angiotensin-converting enzyme 2 in the rostral ventrolateral medulla causes long-term decrease in blood pressure in the spontaneously hypertensive rats
    • doi:10.1161/01.HYP.0000259942.38108.20
    • Yamazato M, Yamazato Y, Sun C, Diez-Freire C, Raizada MK. Overexpression of angiotensin-converting enzyme 2 in the rostral ventrolateral medulla causes long-term decrease in blood pressure in the spontaneously hypertensive rats. Hypertension (2007) 49(4):926-31. doi:10.1161/01.HYP.0000259942.38108.20
    • (2007) Hypertension , vol.49 , Issue.4 , pp. 926-931
    • Yamazato, M.1    Yamazato, Y.2    Sun, C.3    Diez-Freire, C.4    Raizada, M.K.5
  • 109
    • 33749437743 scopus 로고    scopus 로고
    • ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR
    • doi:10.1152/physiolgenomics.00312.2005
    • Diez-Freire C, Vazquez J, Correa de Adjounian MF, Ferrari MF, Yuan L, Silver X, et al. ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR. Physiol Genomics (2006) 27(1):12-9. doi:10.1152/physiolgenomics.00312.2005
    • (2006) Physiol Genomics , vol.27 , Issue.1 , pp. 12-19
    • Diez-Freire, C.1    Vazquez, J.2    Correa de Adjounian, M.F.3    Ferrari, M.F.4    Yuan, L.5    Silver, X.6
  • 110
    • 39749202869 scopus 로고    scopus 로고
    • Cardiac overexpression of angiotensin converting enzyme 2 protects the heart from ischemia-induced pathophysiology
    • doi:10.1161/HYPERTENSIONAHA.107.100693
    • Der SS, Grobe JL, Yuan L, Narielwala DR, Walter GA, Katovich MJ, et al. Cardiac overexpression of angiotensin converting enzyme 2 protects the heart from ischemia-induced pathophysiology. Hypertension (2008) 51(3):712-8. doi:10.1161/HYPERTENSIONAHA.107.100693
    • (2008) Hypertension , vol.51 , Issue.3 , pp. 712-718
    • Der, S.S.1    Grobe, J.L.2    Yuan, L.3    Narielwala, D.R.4    Walter, G.A.5    Katovich, M.J.6
  • 111
    • 84871858948 scopus 로고    scopus 로고
    • Intermedin protects against renal ischemia-reperfusion injury by inhibition of oxidative stress
    • doi:10.1152/ajprenal.00054.2012
    • Qiao X, Li RS, Li H, Zhu GZ, Huang XG, Shao S, et al. Intermedin protects against renal ischemia-reperfusion injury by inhibition of oxidative stress. Am J Physiol Renal Physiol (2013) 304(1):F112-9. doi:10.1152/ajprenal.00054.2012
    • (2013) Am J Physiol Renal Physiol , vol.304 , Issue.1
    • Qiao, X.1    Li, R.S.2    Li, H.3    Zhu, G.Z.4    Huang, X.G.5    Shao, S.6
  • 113
    • 84868206387 scopus 로고    scopus 로고
    • Low-sodium dietary approaches to stop hypertension diet reduces blood pressure, arterial stiffness, and oxidative stress in hypertensive heart failure with preserved ejection fraction
    • doi:10.1161/HYPERTENSIONAHA.112.202705
    • Hummel SL, Seymour EM, Brook RD, Kolias TJ, Sheth SS, Rosenblum HR, et al. Low-sodium dietary approaches to stop hypertension diet reduces blood pressure, arterial stiffness, and oxidative stress in hypertensive heart failure with preserved ejection fraction. Hypertension (2012) 60(5):1200-6. doi:10.1161/HYPERTENSIONAHA.112.202705
    • (2012) Hypertension , vol.60 , Issue.5 , pp. 1200-1206
    • Hummel, S.L.1    Seymour, E.M.2    Brook, R.D.3    Kolias, T.J.4    Sheth, S.S.5    Rosenblum, H.R.6
  • 114
    • 0035804277 scopus 로고    scopus 로고
    • Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group
    • doi:10.1056/NEJM200101043440101
    • Sacks FM, Svetkey LP, Vollmer WM, Appel LJ, Bray GA, Harsha D, et al. Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group. N Engl J Med (2001) 344(1):3-10. doi:10.1056/NEJM200101043440101
    • (2001) N Engl J Med , vol.344 , Issue.1 , pp. 3-10
    • Sacks, F.M.1    Svetkey, L.P.2    Vollmer, W.M.3    Appel, L.J.4    Bray, G.A.5    Harsha, D.6
  • 115
    • 84867313797 scopus 로고    scopus 로고
    • Altered regional blood flow distribution in Mas-deficient mice
    • doi:10.1177/1753944712461164
    • Botelho-Santos GA, Bader M, Alenina N, Santos RA. Altered regional blood flow distribution in Mas-deficient mice. Ther Adv Cardiovasc Dis (2012) 6(5):201-11. doi:10.1177/1753944712461164
    • (2012) Ther Adv Cardiovasc Dis , vol.6 , Issue.5 , pp. 201-211
    • Botelho-Santos, G.A.1    Bader, M.2    Alenina, N.3    Santos, R.A.4
  • 116
    • 0033631744 scopus 로고    scopus 로고
    • Altered heart rate and blood pressure variability in mice lacking the Mas protooncogene
    • doi:10.1590/S0100-879X2000000100001
    • Walther T, Wessel N, Kang N, Sander A, Tschope C, Malberg H, et al. Altered heart rate and blood pressure variability in mice lacking the Mas protooncogene. Braz J Med Biol Res (2000) 33(1):1-9. doi:10.1590/S0100-879X2000000100001
    • (2000) Braz J Med Biol Res , vol.33 , Issue.1 , pp. 1-9
    • Walther, T.1    Wessel, N.2    Kang, N.3    Sander, A.4    Tschope, C.5    Malberg, H.6
  • 117
    • 84864278683 scopus 로고    scopus 로고
    • The genetic deletion of Mas abolishes salt induced hypertension in mice
    • doi:10.1016/j.ejphar.2012.05.025
    • Heringer-Walther S, Gembardt F, Perschel FH, Katz N, Schultheiss HP, Walther T. The genetic deletion of Mas abolishes salt induced hypertension in mice. Eur J Pharmacol (2012) 689(1-3):147-53. doi:10.1016/j.ejphar.2012.05.025
    • (2012) Eur J Pharmacol , vol.689 , Issue.1-3 , pp. 147-153
    • Heringer-Walther, S.1    Gembardt, F.2    Perschel, F.H.3    Katz, N.4    Schultheiss, H.P.5    Walther, T.6
  • 118
    • 77956692408 scopus 로고    scopus 로고
    • Altered cardiovascular reflexes responses in conscious Angiotensin-(1-7) receptor Mas-knockout mice
    • doi:10.1016/j.peptides.2010.06.030
    • de Moura MM, dos Santos RA, Campagnole-Santos MJ, Todiras M, Bader M, Alenina N, et al. Altered cardiovascular reflexes responses in conscious Angiotensin-(1-7) receptor Mas-knockout mice. Peptides (2010) 31(10):1934-9. doi:10.1016/j.peptides.2010.06.030
    • (2010) Peptides , vol.31 , Issue.10 , pp. 1934-1939
    • de Moura, M.M.1    dos Santos, R.A.2    Campagnole-Santos, M.J.3    Todiras, M.4    Bader, M.5    Alenina, N.6
  • 119
    • 42649141954 scopus 로고    scopus 로고
    • Genetically altered animal models for Mas and angiotensin-(1-7)
    • doi:10.1113/expphysiol.2007.040345
    • Alenina N, Xu P, Rentzsch B, Patkin EL, Bader M. Genetically altered animal models for Mas and angiotensin-(1-7). Exp Physiol (2008) 93(5):528-37. doi:10.1113/expphysiol.2007.040345
    • (2008) Exp Physiol , vol.93 , Issue.5 , pp. 528-537
    • Alenina, N.1    Xu, P.2    Rentzsch, B.3    Patkin, E.L.4    Bader, M.5
  • 120
    • 67349127050 scopus 로고    scopus 로고
    • Genetic deletion of the angiotensin-(1-7) receptor Mas leads to glomerular hyperfiltration and microalbuminuria
    • doi:10.1038/ki.2009.61
    • Pinheiro SV, Ferreira AJ, Kitten GT, da Silveira KD, da Silva DA, Santos SH, et al. Genetic deletion of the angiotensin-(1-7) receptor Mas leads to glomerular hyperfiltration and microalbuminuria. Kidney Int (2009) 75(11):1184-93. doi:10.1038/ki.2009.61
    • (2009) Kidney Int , vol.75 , Issue.11 , pp. 1184-1193
    • Pinheiro, S.V.1    Ferreira, A.J.2    Kitten, G.T.3    da Silveira, K.D.4    da Silva, D.A.5    Santos, S.H.6
  • 121
    • 65549108738 scopus 로고    scopus 로고
    • Angiotensin-(1-7) and the G protein-coupled receptor MAS are key players in renal inflammation
    • doi:10.1371/journal.pone.0005406
    • Esteban V, Heringer-Walther S, Sterner-Kock A, de BR, van den Engel S, Wang Y, et al. Angiotensin-(1-7) and the G protein-coupled receptor MAS are key players in renal inflammation. PLoS One (2009) 4(4):e5406. doi:10.1371/journal.pone.0005406
    • (2009) PLoS One , vol.4 , Issue.4
    • Esteban, V.1    Heringer-Walther, S.2    Sterner-Kock, A.3    de, B.R.4    van den Engel, S.5    Wang, Y.6
  • 122
    • 84862561605 scopus 로고    scopus 로고
    • Angiotensin-(1-7) in kidney disease: a review of the controversies
    • doi:10.1042/CS20120111
    • Zimmerman D, Burns KD. Angiotensin-(1-7) in kidney disease: a review of the controversies. Clin Sci (Lond) (2012) 123(6):333-46. doi:10.1042/CS20120111
    • (2012) Clin Sci (Lond) , vol.123 , Issue.6 , pp. 333-346
    • Zimmerman, D.1    Burns, K.D.2
  • 123
    • 0017225440 scopus 로고
    • Mechanisms regulating renin release
    • Davis JO, Freeman RH. Mechanisms regulating renin release. Physiol Rev (1976) 56(1):1-56.
    • (1976) Physiol Rev , vol.56 , Issue.1 , pp. 1-56
    • Davis, J.O.1    Freeman, R.H.2
  • 124
    • 0024495446 scopus 로고
    • Renin, prorenin, and immunoreactive renin in vitreous fluid from eyes with and without diabetic retinopathy
    • doi:10.1210/jcem-68-1-160
    • Danser AH, van den Dorpel MA, Deinum J, Derkx FH, Franken AA, Peperkamp E, et al. Renin, prorenin, and immunoreactive renin in vitreous fluid from eyes with and without diabetic retinopathy. J Clin Endocrinol Metab (1989) 68(1):160-7. doi:10.1210/jcem-68-1-160
    • (1989) J Clin Endocrinol Metab , vol.68 , Issue.1 , pp. 160-167
    • Danser, A.H.1    van den Dorpel, M.A.2    Deinum, J.3    Derkx, F.H.4    Franken, A.A.5    Peperkamp, E.6
  • 125
    • 73349109829 scopus 로고    scopus 로고
    • Prorenin contributes to angiotensin peptide formation in transgenic rats with rat prorenin expression targeted to the liver
    • doi:10.1161/HYPERTENSIONAHA.109.138495
    • Campbell DJ, Karam H, Menard J, Bruneval P, Mullins JJ. Prorenin contributes to angiotensin peptide formation in transgenic rats with rat prorenin expression targeted to the liver. Hypertension (2009) 54(6):1248-53. doi:10.1161/HYPERTENSIONAHA.109.138495
    • (2009) Hypertension , vol.54 , Issue.6 , pp. 1248-1253
    • Campbell, D.J.1    Karam, H.2    Menard, J.3    Bruneval, P.4    Mullins, J.J.5
  • 126
    • 42349091494 scopus 로고    scopus 로고
    • Critical review of prorenin and (pro)renin receptor research
    • doi:10.1161/HYPERTENSIONAHA.108.110924
    • Campbell DJ. Critical review of prorenin and (pro)renin receptor research. Hypertension (2008) 51(5):1259-64. doi:10.1161/HYPERTENSIONAHA.108.110924
    • (2008) Hypertension , vol.51 , Issue.5 , pp. 1259-1264
    • Campbell, D.J.1
  • 127
    • 0029853814 scopus 로고    scopus 로고
    • Specific receptor binding of renin on human mesangial cells in culture increases plasminogen activator inhibitor-1 antigen
    • doi:10.1038/ki.1996.511
    • Nguyen G, Delarue F, Berrou J, Rondeau E, Sraer JD. Specific receptor binding of renin on human mesangial cells in culture increases plasminogen activator inhibitor-1 antigen. Kidney Int (1996) 50(6):1897-903. doi:10.1038/ki.1996.511
    • (1996) Kidney Int , vol.50 , Issue.6 , pp. 1897-1903
    • Nguyen, G.1    Delarue, F.2    Berrou, J.3    Rondeau, E.4    Sraer, J.D.5
  • 128
    • 9644283069 scopus 로고    scopus 로고
    • Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin
    • doi:10.1172/JCI21398
    • Ichihara A, Hayashi M, Kaneshiro Y, Suzuki F, Nakagawa T, Tada Y, et al. Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin. J Clin Invest (2004) 114(8):1128-35. doi:10.1172/JCI21398
    • (2004) J Clin Invest , vol.114 , Issue.8 , pp. 1128-1135
    • Ichihara, A.1    Hayashi, M.2    Kaneshiro, Y.3    Suzuki, F.4    Nakagawa, T.5    Tada, Y.6
  • 129
    • 33745824649 scopus 로고    scopus 로고
    • Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice
    • doi:10.1681/ASN.2006010029
    • Ichihara A, Suzuki F, Nakagawa T, Kaneshiro Y, Takemitsu T, Sakoda M, et al. Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice. J Am Soc Nephrol (2006) 17(7):1950-61. doi:10.1681/ASN.2006010029
    • (2006) J Am Soc Nephrol , vol.17 , Issue.7 , pp. 1950-1961
    • Ichihara, A.1    Suzuki, F.2    Nakagawa, T.3    Kaneshiro, Y.4    Takemitsu, T.5    Sakoda, M.6
  • 130
    • 34447287846 scopus 로고    scopus 로고
    • Renin and its putative receptor remain enigmas
    • doi:10.1681/ASN.2007050558
    • Luft FC. Renin and its putative receptor remain enigmas. J Am Soc Nephrol (2007) 18(7):1989-92. doi:10.1681/ASN.2007050558
    • (2007) J Am Soc Nephrol , vol.18 , Issue.7 , pp. 1989-1992
    • Luft, F.C.1
  • 131
    • 42249089770 scopus 로고    scopus 로고
    • The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling
    • doi:10.1681/ASN.2007091030
    • Feldt S, Maschke U, Dechend R, Luft FC, Muller DN. The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling. J Am Soc Nephrol (2008) 19(4):743-8. doi:10.1681/ASN.2007091030
    • (2008) J Am Soc Nephrol , vol.19 , Issue.4 , pp. 743-748
    • Feldt, S.1    Maschke, U.2    Dechend, R.3    Luft, F.C.4    Muller, D.N.5
  • 132
    • 39749098706 scopus 로고    scopus 로고
    • Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide
    • doi:10.1161/HYPERTENSIONAHA.107.101444
    • Feldt S, Batenburg WW, Mazak I, Maschke U, Wellner M, Kvakan H, et al. Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide. Hypertension (2008) 51(3):682-8. doi:10.1161/HYPERTENSIONAHA.107.101444
    • (2008) Hypertension , vol.51 , Issue.3 , pp. 682-688
    • Feldt, S.1    Batenburg, W.W.2    Mazak, I.3    Maschke, U.4    Wellner, M.5    Kvakan, H.6
  • 133
    • 39749088803 scopus 로고    scopus 로고
    • (Pro)renin receptor peptide inhibitor "handle-region" peptide does not affect hypertensive nephrosclerosis in Goldblatt rats
    • doi:10.1161/HYPERTENSIONAHA.107.101493
    • Muller DN, Klanke B, Feldt S, Cordasic N, Hartner A, Schmieder RE, et al. (Pro)renin receptor peptide inhibitor "handle-region" peptide does not affect hypertensive nephrosclerosis in Goldblatt rats. Hypertension (2008) 51(3):676-81. doi:10.1161/HYPERTENSIONAHA.107.101493
    • (2008) Hypertension , vol.51 , Issue.3 , pp. 676-681
    • Muller, D.N.1    Klanke, B.2    Feldt, S.3    Cordasic, N.4    Hartner, A.5    Schmieder, R.E.6
  • 135
    • 84873055293 scopus 로고    scopus 로고
    • Angiotensin II-independent upregulation of cyclooxygenase-2 by activation of the (Pro)renin receptor in rat renal inner medullary cells
    • doi:10.1161/HYPERTENSIONAHA.112.196303
    • Gonzalez AA, Luffman C, Bourgeois CR, Vio CP, Prieto MC. Angiotensin II-independent upregulation of cyclooxygenase-2 by activation of the (Pro)renin receptor in rat renal inner medullary cells. Hypertension (2013) 61(2):443-9. doi:10.1161/HYPERTENSIONAHA.112.196303
    • (2013) Hypertension , vol.61 , Issue.2 , pp. 443-449
    • Gonzalez, A.A.1    Luffman, C.2    Bourgeois, C.R.3    Vio, C.P.4    Prieto, M.C.5
  • 136
    • 84881006424 scopus 로고    scopus 로고
    • (Pro)renin receptor is required for prorenin-dependent and-independent regulation of vacuolar H+-ATPase activity in MDCK.C11 collecting duct cells
    • doi:10.1152/ajprenal.00037.2013
    • Lu X, Garrelds IM, Wagner CA, Danser AH, Meima ME. (Pro)renin receptor is required for prorenin-dependent and-independent regulation of vacuolar H+-ATPase activity in MDCK.C11 collecting duct cells. Am J Physiol Renal Physiol (2013) 305(3):F417-25. doi:10.1152/ajprenal.00037.2013
    • (2013) Am J Physiol Renal Physiol , vol.305 , Issue.3
    • Lu, X.1    Garrelds, I.M.2    Wagner, C.A.3    Danser, A.H.4    Meima, M.E.5
  • 137
    • 77954762963 scopus 로고    scopus 로고
    • The (pro)renin receptor/ATP6AP2 is essential for vacuolar H+-ATPase assembly in murine cardiomyocytes
    • doi:10.1161/CIRCRESAHA.110.224667
    • Kinouchi K, Ichihara A, Sano M, Sun-Wada GH, Wada Y, Kurauchi-Mito A, et al. The (pro)renin receptor/ATP6AP2 is essential for vacuolar H+-ATPase assembly in murine cardiomyocytes. Circ Res (2010) 107(1):30-4. doi:10.1161/CIRCRESAHA.110.224667
    • (2010) Circ Res , vol.107 , Issue.1 , pp. 30-34
    • Kinouchi, K.1    Ichihara, A.2    Sano, M.3    Sun-Wada, G.H.4    Wada, Y.5    Kurauchi-Mito, A.6
  • 138
    • 82655181486 scopus 로고    scopus 로고
    • Prorenin receptor is essential for normal podocyte structure and function
    • doi:10.1681/ASN.2011020202
    • Oshima Y, Kinouchi K, Ichihara A, Sakoda M, Kurauchi-Mito A, Bokuda K, et al. Prorenin receptor is essential for normal podocyte structure and function. J Am Soc Nephrol (2011) 22(12):2203-12. doi:10.1681/ASN.2011020202
    • (2011) J Am Soc Nephrol , vol.22 , Issue.12 , pp. 2203-2212
    • Oshima, Y.1    Kinouchi, K.2    Ichihara, A.3    Sakoda, M.4    Kurauchi-Mito, A.5    Bokuda, K.6
  • 139
    • 34249881320 scopus 로고    scopus 로고
    • Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats
    • doi:10.1681/ASN.2006091062
    • Kaneshiro Y, Ichihara A, Sakoda M, Takemitsu T, Nabi AH, Uddin MN, et al. Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats. J Am Soc Nephrol (2007) 18(6):1789-95. doi:10.1681/ASN.2006091062
    • (2007) J Am Soc Nephrol , vol.18 , Issue.6 , pp. 1789-1795
    • Kaneshiro, Y.1    Ichihara, A.2    Sakoda, M.3    Takemitsu, T.4    Nabi, A.H.5    Uddin, M.N.6
  • 140
    • 40649124722 scopus 로고    scopus 로고
    • Physiology and pharmacology of the (pro)renin receptor
    • doi:10.1016/j.coph.2007.12.009
    • Nguyen G, Contrepas A. Physiology and pharmacology of the (pro)renin receptor. Curr Opin Pharmacol (2008) 8(2):127-32. doi:10.1016/j.coph.2007.12.009
    • (2008) Curr Opin Pharmacol , vol.8 , Issue.2 , pp. 127-132
    • Nguyen, G.1    Contrepas, A.2
  • 141
    • 75149122361 scopus 로고    scopus 로고
    • The (pro)renin receptor in health and disease
    • doi:10.3109/07853890903321567
    • Nguyen G. The (pro)renin receptor in health and disease. Ann Med (2010) 42(1):13-8. doi:10.3109/07853890903321567
    • (2010) Ann Med , vol.42 , Issue.1 , pp. 13-18
    • Nguyen, G.1
  • 142
    • 75649120756 scopus 로고    scopus 로고
    • Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling
    • doi:10.1126/science.1179802
    • Cruciat CM, Ohkawara B, Acebron SP, Karaulanov E, Reinhard C, Ingelfinger D, et al. Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling. Science (2010) 327(5964):459-63. doi:10.1126/science.1179802
    • (2010) Science , vol.327 , Issue.5964 , pp. 459-463
    • Cruciat, C.M.1    Ohkawara, B.2    Acebron, S.P.3    Karaulanov, E.4    Reinhard, C.5    Ingelfinger, D.6
  • 143
    • 68549136748 scopus 로고    scopus 로고
    • +-ATPase
    • doi:10.1161/HYPERTENSIONAHA.109.135236
    • +-ATPase. Hypertension (2009b) 54(2):219-21. doi:10.1161/HYPERTENSIONAHA.109.135236
    • (2009) Hypertension , vol.54 , Issue.2 , pp. 219-221
    • Danser, A.H.1
  • 144
    • 67049100691 scopus 로고    scopus 로고
    • Chronic increases in circulating prorenin are not associated with renal or cardiac pathologies
    • doi:10.1161/HYPERTENSIONAHA.108.115444
    • Mercure C, Prescott G, Lacombe MJ, Silversides DW, Reudelhuber TL. Chronic increases in circulating prorenin are not associated with renal or cardiac pathologies. Hypertension (2009) 53(6):1062-9. doi:10.1161/HYPERTENSIONAHA.108.115444
    • (2009) Hypertension , vol.53 , Issue.6 , pp. 1062-1069
    • Mercure, C.1    Prescott, G.2    Lacombe, M.J.3    Silversides, D.W.4    Reudelhuber, T.L.5
  • 145
    • 37349054998 scopus 로고    scopus 로고
    • Dose-dependent titration of prorenin and blood pressure in Cyp1a1ren-2 transgenic rats: absence of prorenin-induced glomerulosclerosis
    • doi:10.1097/HJH.0b013e3282f0ab66
    • Peters B, Grisk O, Becher B, Wanka H, Kuttler B, Ludemann J, et al. Dose-dependent titration of prorenin and blood pressure in Cyp1a1ren-2 transgenic rats: absence of prorenin-induced glomerulosclerosis. J Hypertens (2008) 26(1):102-9. doi:10.1097/HJH.0b013e3282f0ab66
    • (2008) J Hypertens , vol.26 , Issue.1 , pp. 102-109
    • Peters, B.1    Grisk, O.2    Becher, B.3    Wanka, H.4    Kuttler, B.5    Ludemann, J.6
  • 146
    • 77952623456 scopus 로고    scopus 로고
    • Transgenic mice expressing an intracellular fluorescent fusion of angiotensin II demonstrate renal thrombotic microangiopathy and elevated blood pressure
    • doi:10.1152/ajpheart.00027.2010
    • Redding KM, Chen BL, Singh A, Re RN, Navar LG, Seth DM, et al. Transgenic mice expressing an intracellular fluorescent fusion of angiotensin II demonstrate renal thrombotic microangiopathy and elevated blood pressure. Am J Physiol Heart Circ Physiol (2010) 298:H1807-18. doi:10.1152/ajpheart.00027.2010
    • (2010) Am J Physiol Heart Circ Physiol , vol.298
    • Redding, K.M.1    Chen, B.L.2    Singh, A.3    Re, R.N.4    Navar, L.G.5    Seth, D.M.6
  • 147
    • 0034097940 scopus 로고    scopus 로고
    • On the biological actions of intracellular angiotensin
    • doi:10.1161/01.HYP.35.6.1189
    • Re RN. On the biological actions of intracellular angiotensin. Hypertension (2000) 35(6):1189-90. doi:10.1161/01.HYP.35.6.1189
    • (2000) Hypertension , vol.35 , Issue.6 , pp. 1189-1190
    • Re, R.N.1
  • 148
    • 0035824901 scopus 로고    scopus 로고
    • In vitro evidence for an intracellular site of angiotensin action
    • doi:10.1161/hh2401.101270
    • Cook JL, Zhang Z, Re RN. In vitro evidence for an intracellular site of angiotensin action. Circ Res (2001) 89(12):1138-46. doi:10.1161/hh2401.101270
    • (2001) Circ Res , vol.89 , Issue.12 , pp. 1138-1146
    • Cook, J.L.1    Zhang, Z.2    Re, R.N.3
  • 149
    • 0029822199 scopus 로고    scopus 로고
    • Effects of intracellular angiotensin II in vascular smooth muscle cells
    • doi:10.1161/01.RES.79.4.765
    • Haller H, Lindschau C, Erdmann B, Quass P, Luft FC. Effects of intracellular angiotensin II in vascular smooth muscle cells. Circ Res (1996) 79(4):765-72. doi:10.1161/01.RES.79.4.765
    • (1996) Circ Res , vol.79 , Issue.4 , pp. 765-772
    • Haller, H.1    Lindschau, C.2    Erdmann, B.3    Quass, P.4    Luft, F.C.5
  • 151
    • 33646838756 scopus 로고    scopus 로고
    • AT1 receptor-mediated accumulation of extracellular angiotensin II in proximal tubule cells: role of cytoskeleton microtubules and tyrosine phosphatases
    • doi:10.1152/ajprenal.00405.2005
    • Li XC, Carretero OA, Navar LG, Zhuo JL. AT1 receptor-mediated accumulation of extracellular angiotensin II in proximal tubule cells: role of cytoskeleton microtubules and tyrosine phosphatases. Am J Physiol Renal Physiol (2006) 291:F375-83. doi:10.1152/ajprenal.00405.2005
    • (2006) Am J Physiol Renal Physiol , vol.291
    • Li, X.C.1    Carretero, O.A.2    Navar, L.G.3    Zhuo, J.L.4
  • 152
    • 70350702799 scopus 로고    scopus 로고
    • 1 receptor-mediated uptake of angiotensin II and NHE-3 expression in proximal tubule cells through the microtubule-dependent endocytic pathway
    • doi:10.1152/ajprenal.90734.2008
    • 1 receptor-mediated uptake of angiotensin II and NHE-3 expression in proximal tubule cells through the microtubule-dependent endocytic pathway. Am J Physiol Renal Physiol (2009) 297(5):F1342-52. doi:10.1152/ajprenal.90734.2008
    • (2009) Am J Physiol Renal Physiol , vol.297 , Issue.5
    • Li, X.C.1    Hopfer, U.2    Zhuo, J.L.3
  • 153
    • 0028355709 scopus 로고
    • In vivo occupancy of angiotensin II subtype 1 receptors in rat renal medullary interstitial cells
    • doi:10.1161/01.HYP.23.6.838
    • Zhuo JL, Alcorn D, McCausland J, Casley D, Mendelsohn FA. In vivo occupancy of angiotensin II subtype 1 receptors in rat renal medullary interstitial cells. Hypertension (1994) 23(6 Pt 2):838-43. doi:10.1161/01.HYP.23.6.838
    • (1994) Hypertension , vol.2 , Issue.PART 2 , pp. 838-843
    • Zhuo, J.L.1    Alcorn, D.2    McCausland, J.3    Casley, D.4    Mendelsohn, F.A.5
  • 155
    • 80052585322 scopus 로고    scopus 로고
    • Identification and characterization of a functional mitochondrial angiotensin system
    • doi:10.1073/pnas.1101507108
    • Abadir PM, Foster DB, Crow M, Cooke CA, Rucker JJ, Jain A, et al. Identification and characterization of a functional mitochondrial angiotensin system. Proc Natl Acad Sci U S A (2011) 108(36):14849-54. doi:10.1073/pnas.1101507108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.36 , pp. 14849-14854
    • Abadir, P.M.1    Foster, D.B.2    Crow, M.3    Cooke, C.A.4    Rucker, J.J.5    Jain, A.6
  • 156
    • 41949119685 scopus 로고    scopus 로고
    • 1a receptors
    • doi:10.1152/ajpcell.00432.2007
    • 1a receptors. Am J Physiol Cell Physiol (2008b) 294(4):C1034-45. doi:10.1152/ajpcell.00432.2007
    • (2008) Am J Physiol Cell Physiol , vol.294 , Issue.4
    • Li, X.C.1    Zhuo, J.L.2
  • 158
    • 78349247835 scopus 로고    scopus 로고
    • Nuclear angiotensin-(1-7) receptor is functionally coupled to the formation of nitric oxide
    • doi:10.1152/ajprenal.00371.2010
    • Gwathmey TM, Westwood BM, Pirro NT, Tang L, Rose JC, Diz DI, et al. Nuclear angiotensin-(1-7) receptor is functionally coupled to the formation of nitric oxide. Am J Physiol Renal Physiol (2010) 299(5):F983-90. doi:10.1152/ajprenal.00371.2010
    • (2010) Am J Physiol Renal Physiol , vol.299 , Issue.5
    • Gwathmey, T.M.1    Westwood, B.M.2    Pirro, N.T.3    Tang, L.4    Rose, J.C.5    Diz, D.I.6
  • 160
    • 0028207508 scopus 로고
    • Angiotensin II-dependent proximal tubule sodium transport requires receptor-mediated endocytosis
    • Schelling JR, Linas SL. Angiotensin II-dependent proximal tubule sodium transport requires receptor-mediated endocytosis. Am J Physiol (1994) 266(3 Pt 1):C669-75.
    • (1994) Am J Physiol , vol.266 , Issue.3 PART 1
    • Schelling, J.R.1    Linas, S.L.2
  • 161
    • 0027099649 scopus 로고
    • Cytoskeleton-dependent endocytosis is required for apical type 1 angiotensin II receptor-mediated phospholipase C activation in cultured rat proximal tubule cells
    • doi:10.1172/JCI116139
    • Schelling JR, Hanson AS, Marzec R, Linas SL. Cytoskeleton-dependent endocytosis is required for apical type 1 angiotensin II receptor-mediated phospholipase C activation in cultured rat proximal tubule cells. J Clin Invest (1992) 90(6):2472-80. doi:10.1172/JCI116139
    • (1992) J Clin Invest , vol.90 , Issue.6 , pp. 2472-2480
    • Schelling, J.R.1    Hanson, A.S.2    Marzec, R.3    Linas, S.L.4
  • 162
    • 0032062064 scopus 로고    scopus 로고
    • 1A) receptor-mediated increases in transcellular sodium transport in proximal tubule cells
    • 1A) receptor-mediated increases in transcellular sodium transport in proximal tubule cells. Am J Physiol (1998) 274:F897-905.
    • (1998) Am J Physiol , vol.274
    • Thekkumkara, T.J.1    Cookson, R.2    Linas, S.L.3
  • 163
    • 33947575597 scopus 로고    scopus 로고
    • 1 receptor-mediated endocytosis of extracellular Ang II on activation of nuclear factor-kappa B in proximal tubule cells
    • doi:10.1196/annals.1378.078
    • 1 receptor-mediated endocytosis of extracellular Ang II on activation of nuclear factor-kappa B in proximal tubule cells. Ann N Y Acad Sci (2006) 1091:336-45. doi:10.1196/annals.1378.078
    • (2006) Ann N Y Acad Sci , vol.1091 , pp. 336-345
    • Zhuo, J.L.1    Carretero, O.A.2    Li, X.C.3
  • 164
    • 34547119295 scopus 로고    scopus 로고
    • 1 receptors by RNA interference inhibits Val5-Ang II endocytosis and NHE-3 expression in immortalized rabbit proximal tubule cells
    • doi:10.1152/ajpcell.00463.2006
    • 1 receptors by RNA interference inhibits Val5-Ang II endocytosis and NHE-3 expression in immortalized rabbit proximal tubule cells. Am J Physiol Cell Physiol (2007) 293:C367-78. doi:10.1152/ajpcell.00463.2006
    • (2007) Am J Physiol Cell Physiol , vol.293
    • Li, X.C.1    Zhuo, J.L.2
  • 165
    • 73849117533 scopus 로고    scopus 로고
    • Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus
    • doi:10.1161/HYPERTENSIONAHA.109.141622
    • Gwathmey TM, Pendergrass KD, Reid SD, Rose JC, Diz DI, Chappell MC. Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus. Hypertension (2010) 55(1):166-71. doi:10.1161/HYPERTENSIONAHA.109.141622
    • (2010) Hypertension , vol.55 , Issue.1 , pp. 166-171
    • Gwathmey, T.M.1    Pendergrass, K.D.2    Reid, S.D.3    Rose, J.C.4    Diz, D.I.5    Chappell, M.C.6
  • 166
    • 84871263645 scopus 로고    scopus 로고
    • Novel signaling mechanisms of intracellular angiotensin II-induced NHE3 expression and activation in mouse proximal tubule cells
    • doi:10.1152/ajprenal.00219.2012
    • Li XC, Hopfer U, Zhuo JL. Novel signaling mechanisms of intracellular angiotensin II-induced NHE3 expression and activation in mouse proximal tubule cells. Am J Physiol Renal Physiol (2012) 303(12):F1617-28. doi:10.1152/ajprenal.00219.2012
    • (2012) Am J Physiol Renal Physiol , vol.303 , Issue.12
    • Li, X.C.1    Hopfer, U.2    Zhuo, J.L.3
  • 168
    • 84885004860 scopus 로고    scopus 로고
    • Angiotensin III: a physiological relevant peptide of the renin angiotensin system
    • doi:10.1016/j.peptides.2013.04.014
    • Yugandhar VG, Clark MA. Angiotensin III: a physiological relevant peptide of the renin angiotensin system. Peptides (2013) 46:26-32. doi:10.1016/j.peptides.2013.04.014
    • (2013) Peptides , vol.46 , pp. 26-32
    • Yugandhar, V.G.1    Clark, M.A.2
  • 169
    • 0036563250 scopus 로고    scopus 로고
    • Biological properties of the angiotensin peptides other than angiotensin II: implications for hypertension and cardiovascular diseases
    • doi:10.1097/00004872-200205000-00002
    • Cesari M, Rossi GP, Pessina AC. Biological properties of the angiotensin peptides other than angiotensin II: implications for hypertension and cardiovascular diseases. J Hypertens (2002) 20(5):793-9. doi:10.1097/00004872-200205000-00002
    • (2002) J Hypertens , vol.20 , Issue.5 , pp. 793-799
    • Cesari, M.1    Rossi, G.P.2    Pessina, A.C.3
  • 170
    • 33847049473 scopus 로고    scopus 로고
    • Intrarenal aminopeptidase N inhibition augments natriuretic responses to angiotensin III in angiotensin type 1 receptor-blocked rats
    • doi:10.1161/01.HYP.0000254833.85106.4d
    • Padia SH, Kemp BA, Howell NL, Siragy HM, Fournie-Zaluski MC, Roques BP, et al. Intrarenal aminopeptidase N inhibition augments natriuretic responses to angiotensin III in angiotensin type 1 receptor-blocked rats. Hypertension (2007) 49(3):625-30. doi:10.1161/01.HYP.0000254833.85106.4d
    • (2007) Hypertension , vol.49 , Issue.3 , pp. 625-630
    • Padia, S.H.1    Kemp, B.A.2    Howell, N.L.3    Siragy, H.M.4    Fournie-Zaluski, M.C.5    Roques, B.P.6
  • 171
    • 0031435757 scopus 로고    scopus 로고
    • Synthesis and effects of active fragments of angiotensin II
    • doi:10.1038/ki.1997.476
    • Ardaillou R, Chansel D. Synthesis and effects of active fragments of angiotensin II. Kidney Int (1997) 52(6):1458-68. doi:10.1038/ki.1997.476
    • (1997) Kidney Int , vol.52 , Issue.6 , pp. 1458-1468
    • Ardaillou, R.1    Chansel, D.2
  • 173
    • 78650171633 scopus 로고    scopus 로고
    • Distinct distribution of GLUT4 and insulin regulated aminopeptidase in the mouse kidney
    • doi:10.1016/j.regpep.2010.09.003
    • Albiston AL, Yeatman HR, Pham V, Fuller SJ, Diwakarla S, Fernando RN, et al. Distinct distribution of GLUT4 and insulin regulated aminopeptidase in the mouse kidney. Regul Pept (2011) 166(1-3):83-9. doi:10.1016/j.regpep.2010.09.003
    • (2011) Regul Pept , vol.166 , Issue.1-3 , pp. 83-89
    • Albiston, A.L.1    Yeatman, H.R.2    Pham, V.3    Fuller, S.J.4    Diwakarla, S.5    Fernando, R.N.6
  • 174
    • 0031591786 scopus 로고    scopus 로고
    • Important role for angiotensin III and IV in the brain renin-angiotensin system
    • doi:10.1016/S0165-0173(97)00019-2
    • Wright JW, Harding JW. Important role for angiotensin III and IV in the brain renin-angiotensin system. Brain Res Brain Res Rev (1997) 25(1):96-124. doi:10.1016/S0165-0173(97)00019-2
    • (1997) Brain Res Brain Res Rev , vol.25 , Issue.1 , pp. 96-124
    • Wright, J.W.1    Harding, J.W.2
  • 176
    • 0037817386 scopus 로고    scopus 로고
    • 4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP)
    • doi:10.1046/j.1471-4159.2003.01852.x
    • 4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP). J Neurochem (2003) 86(2):344-50. doi:10.1046/j.1471-4159.2003.01852.x
    • (2003) J Neurochem , vol.86 , Issue.2 , pp. 344-350
    • Lew, R.A.1    Mustafa, T.2    Ye, S.3    McDowall, S.G.4    Chai, S.Y.5    Albiston, A.L.6
  • 177
    • 0027184742 scopus 로고
    • Regional haemodynamic effects of angiotensin II (3-8) in conscious rats
    • doi:10.1111/j.1476-5381.1993.tb13786.x
    • Gardiner SM, Kemp PA, March JE, Bennett T. Regional haemodynamic effects of angiotensin II (3-8) in conscious rats. Br J Pharmacol (1993) 110(1):159-62. doi:10.1111/j.1476-5381.1993.tb13786.x
    • (1993) Br J Pharmacol , vol.110 , Issue.1 , pp. 159-162
    • Gardiner, S.M.1    Kemp, P.A.2    March, J.E.3    Bennett, T.4
  • 178
    • 0035794028 scopus 로고    scopus 로고
    • Effects of angiotensin IV and angiotensin-(1-7) on basal and angiotensin II-stimulated cytosolic Ca2+ in mesangial cells
    • doi:10.1016/S0014-2999(01)00791-9
    • Chansel D, Vandermeersch S, Oko A, Curat C, Ardaillou R. Effects of angiotensin IV and angiotensin-(1-7) on basal and angiotensin II-stimulated cytosolic Ca2+ in mesangial cells. Eur J Pharmacol (2001) 414(2-3):165-75. doi:10.1016/S0014-2999(01)00791-9
    • (2001) Eur J Pharmacol , vol.414 , Issue.2-3 , pp. 165-175
    • Chansel, D.1    Vandermeersch, S.2    Oko, A.3    Curat, C.4    Ardaillou, R.5
  • 179
    • 0032695629 scopus 로고    scopus 로고
    • Functional evidence for an angiotensin IV receptor in rat resistance arteries
    • Loufrani L, Henrion D, Chansel D, Ardaillou R, Levy BI. Functional evidence for an angiotensin IV receptor in rat resistance arteries. J Pharmacol Exp Ther (1999) 291(2):583-8.
    • (1999) J Pharmacol Exp Ther , vol.291 , Issue.2 , pp. 583-588
    • Loufrani, L.1    Henrion, D.2    Chansel, D.3    Ardaillou, R.4    Levy, B.I.5
  • 180
    • 0032778917 scopus 로고    scopus 로고
    • Renal hemodynamic responses to intrarenal infusion of ligands for the putative angiotensin IV receptor in anesthetized rats
    • doi:10.1097/00005344-199908000-00005
    • Fitzgerald SM, Evans RG, Bergstrom G, Anderson WP. Renal hemodynamic responses to intrarenal infusion of ligands for the putative angiotensin IV receptor in anesthetized rats. J Cardiovasc Pharmacol (1999) 34(2):206-11. doi:10.1097/00005344-199908000-00005
    • (1999) J Cardiovasc Pharmacol , vol.34 , Issue.2 , pp. 206-211
    • Fitzgerald, S.M.1    Evans, R.G.2    Bergstrom, G.3    Anderson, W.P.4
  • 181
    • 0035126258 scopus 로고    scopus 로고
    • 4 receptor in human proximal tubule epithelial (HK-2) cells
    • 4 receptor in human proximal tubule epithelial (HK-2) cells. J Am Soc Nephrol (2001) 12(3):440-9.
    • (2001) J Am Soc Nephrol , vol.12 , Issue.3 , pp. 440-449
    • Handa, R.K.1
  • 183
    • 42049085291 scopus 로고    scopus 로고
    • Brain and peripheral angiotensin II type 1 receptors mediate renal vasoconstrictor and blood pressure responses to angiotensin IV in the rat
    • doi:10.1097/HJH.0b013e3282f5ed58
    • Yang R, Smolders I, De BD, Fouyn R, Halberg M, Demaegdt H, et al. Brain and peripheral angiotensin II type 1 receptors mediate renal vasoconstrictor and blood pressure responses to angiotensin IV in the rat. J Hypertens (2008) 26(5):998-1007. doi:10.1097/HJH.0b013e3282f5ed58
    • (2008) J Hypertens , vol.26 , Issue.5 , pp. 998-1007
    • Yang, R.1    Smolders, I.2    De, B.D.3    Fouyn, R.4    Halberg, M.5    Demaegdt, H.6
  • 185
    • 84876407858 scopus 로고    scopus 로고
    • Discovery and characterization of alamandine: a novel component of the renin-angiotensin system
    • doi:10.1161/CIRCRESAHA.113.301077
    • Lautner RQ, Villela DC, Fraga-Silva RA, Silva N, Verano-Braga T, Costa-Fraga F, et al. Discovery and characterization of alamandine: a novel component of the renin-angiotensin system. Circ Res (2013) 112(8):1104-11. doi:10.1161/CIRCRESAHA.113.301077
    • (2013) Circ Res , vol.112 , Issue.8 , pp. 1104-1111
    • Lautner, R.Q.1    Villela, D.C.2    Fraga-Silva, R.A.3    Silva, N.4    Verano-Braga, T.5    Costa-Fraga, F.6
  • 186
    • 79955479435 scopus 로고    scopus 로고
    • Pressor and renal hemodynamic effects of the novel angiotensin A peptide are angiotensin II type 1A receptor dependent
    • doi:10.1161/HYPERTENSIONAHA.110.161836
    • Yang R, Smolders I, Vanderheyden P, Demaegdt H, Van EA, Vauquelin G, et al. Pressor and renal hemodynamic effects of the novel angiotensin A peptide are angiotensin II type 1A receptor dependent. Hypertension (2011) 57(5):956-64. doi:10.1161/HYPERTENSIONAHA.110.161836
    • (2011) Hypertension , vol.57 , Issue.5 , pp. 956-964
    • Yang, R.1    Smolders, I.2    Vanderheyden, P.3    Demaegdt, H.4    Van, E.A.5    Vauquelin, G.6
  • 187
    • 33846417985 scopus 로고    scopus 로고
    • Mass-spectrometric identification of a novel angiotensin peptide in human plasma
    • doi:10.1161/01.ATV.0000253889.09765.5f
    • Jankowski V, Vanholder R, van der Giet M, Tolle M, Karadogan S, Gobom J, et al. Mass-spectrometric identification of a novel angiotensin peptide in human plasma. Arterioscler Thromb Vasc Biol (2007) 27(2):297-302. doi:10.1161/01.ATV.0000253889.09765.5f
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , Issue.2 , pp. 297-302
    • Jankowski, V.1    Vanholder, R.2    van der Giet, M.3    Tolle, M.4    Karadogan, S.5    Gobom, J.6


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