Increased renin excretion is associated with augmented urinary angiotensin II levels in chronic angiotensin II-infused hypertensive rats

American Journal of Physiology - Renal Physiology

Volumn 301, Issue 6, 2011, Pages

  Liu, Liu ^a   Gonzalez, Alexis A ^a   McCormack, Michael ^a   Seth, Dale M ^a   Kobori, Hiroyuki ^a   Gabriel Navar, L ^a   Prieto, Minolfa C ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Collecting duct renin; Distal nephron; Gene expression; Prorenin; Urinary angiotensinogen

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; CANDESARTAN; PRORENIN; RENIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HYPERTENSION; KIDNEY CORTEX; KIDNEY MEDULLA; MALE; NONHUMAN; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; RAT; SYSTOLIC BLOOD PRESSURE; URINARY EXCRETION; WESTERN BLOTTING;

EID: 82755191651     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00339.2011     Document Type: Article

References (42)

1. Beutler KT, Masilamani S, Turban S, Nielsen J, Brooks HL, Ageloff S, Fenton RA, Packer RK, Knepper MA. Long-term regulation of ENaC expression in kidney by angiotensin II. Hypertension 41: 1143-1150, 2003.
2. Campbell Jr WG, Gahnem F, Catanzaro DF, James GD, Camargo MJF, Laragh JH, Sealey JE. Plasma and renal prorenin/renin, renin mRNA, and blood pressure in Dahl salt-sensitive and salt-resistant rats. Hypertension 27: 1121-1133, 1996.
3. Casarini DE, Boim MA, Stella RCR, Krieger-Azzolini MH, Krieger JE, Schor N. Angiotensin I-converting enzyme activity in tubular fluid along the rat nephron. Am J Physiol Renal Physiol 272: F405-F409, 1997.
4. Casarini DE, Boim MA, Stella RCR, Schor N. Endopeptidases (kininases) are able to hydrolyze kinins in tubular fluid along the rat nephron. Am J Physiol Renal Physiol 276: F66-F74, 1999.
5. Chen M, Harris MP, Rose D, Smart A, He XR, Kretzler M, Briggs JP, Schnermann J. Renin and renin mRNA in proximal tubules of the rat kidney. J Clin Invest 94: 237-243, 1994.
6. Corvol P, Devaux C, Ito T, Sicard P, Ducloux J, Menard J. Large scale purification of hog renin. Physicochemical characterization. Circ Res 41: 616-622, 1977.
7. Cousin C, Bracquart D, Contrepas A, Corvol P, Muller L, Nguyen G. Soluble form of the (pro)renin receptor generated by intracellular cleavage by furin is secreted in plasma. Hypertension 53: 1077-1082, 2009.
8. De Nicola L, Keiser JA, Blantz RC, Gabbai FB. Angiotensin II and renal functional reserve in rats with Goldblatt hypertension. Hypertension 19: 790-792, 1992.
9. Dzau VJ, Slater EE, Haber E. Complete purification of dog renal renin. Biochemistry 18: 5224-5228, 1979.
10. Gonzalez AA, Lara LS, Luffman C, Seth DM, Prieto MC. The soluble form of the prorenin receptor [s(PRR)] is augmented in the collecting ducts and in the urine of angiotensin II (ANG II)-dependent hypertensive rats. Hypertension 57: 859-864, 2011.
11. Hackenthal E, Paul M, Ganten D, Taugner R. Morphology, physiology, and molecular biology of renin secretion. Physiol Rev 70: 1067-1116, 1990.
12. Kang JJ, Toma I, Sipos A, Meer EJ, Vargas SL, Peti-Peterdi J. The collecting duct is the major source of prorenin in diabetes. Hypertension 51: 1597-1604, 2008.
13. Katsurada A, Hagiwara Y, Miyashita K, Satou R, Miyata K, Ohashi N, Navar LG, Kobori H. Novel sandwich ELISA for human angiotensinogen. Am J Physiol Renal Physiol 293: F956-F960, 2007.
14. Kobori H, Harrison-Bernard LM, Navar LG. Enhancement of angiotensinogen expression in angiotensin II-dependent hypertension. Hypertension 37: 1329-1335, 2001.
15. Kobori H, Harrison-Bernard LM, Navar LG. Urinary excretion of angiotensinogen reflects intrarenal angiotensinogen production. Kidney Int 61: 579-585, 2002.
16. Kobori H, Nishiyama A, Harrison-Bernard LM, Navar LG. Urinary angiotensinogen as an indicator of intrarenal Angiotensin status in hypertension. Hypertension 41: 42-49, 2003.
17. Komlosi P, Fuson AL, Fintha A, Peti-Peterdi J, Rosivall L, Warnock DG, Bell PD. Angiotensin I conversion to angiotensin II stimulates cortical collecting duct sodium transport. Hypertension 42: 195-199, 2003.
18. Li XC, Zhuo JL. In vivo regulation of AT1a receptor-mediated intracellular uptake of [125I]Val5-ANG II in the kidneys and adrenals of AT1a receptor-deficient mice. Am J Physiol Renal Physiol 294: F293-F302, 2008.
19. Matoba T, Murakami K, Inagami T. Rat renin: purification and characterization. Biochim Biophys Acta 526: 560-571, 1978.
20. Mitchell KD, Jacinto SM, Mullins JJ. Proximal tubular fluid, kidney, and plasma levels of angiotensin II in hypertensive ren-2 transgenic rats. Am J Physiol Renal Physiol 273: F246-F253, 1997.
21. Moe OW, Ujiie K, Star RA, Miller RT, Widell J, Alpern RJ, Henrich WL. Renin expression in renal proximal tubule. J Clin Invest 91: 774-779, 1993.
22. Navar LG, Harrison-Bernard LM. Intrarenal angiotensin II augmentation in angiotensin II dependent hypertension. Hypertens Res 23: 291-301, 2000.
23. Navar LG, Harrison-Bernard LM, Nishiyama A, Kobori H. Regulation of intrarenal angiotensin II in hypertension. Hypertension 39: 316-322, 2002.
24. Navar LG, Lewis L, Hymel A, Braam B, Mitchell KD. Tubular fluid concentrations and kidney contents of angiotensins I and II in anesthetized rats. J Am Soc Nephrol 5: 1153-1158, 1994.
25. Navar LG, Mitchell KD, Harrison-Bernard LM, Kobori H, Nishiyama A. Intrarenal angiotensin II levels in normal and hypertensive states. JRAAS 2: S176-S184, 2001.
26. Navar LG, Prieto-Carrasquero MC, Kobori H. Renin renin-angiotensin system. In: Handbook of Biologically Active Peptides, edited by Kastin AJ. London: Academic, 2006, p. 1235-1242.
27. Nguyen G, Delarue F, Burckle C, Bouzhir L, Giller T, Sraer JD. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 109: 1417-1427, 2002.
28. Peti-Peterdi J, Warnock DG, Bell PD. Angiotensin II directly stimulates ENaC activity in the cortical collecting duct via AT(1) receptors. J Am Soc Nephrol 13: 1131-1135, 2002.
29. Pohl M, Kaminski H, Castrop H, Bader M, Himmerkus N, Bleich M, Bachmann S, Theilig F. Intrarenal renin angiotensin system revisited. J Biol Chem 285: 41935-41946, 2010.
30. Prieto MC, Williams DE, Liu L, Kavanagh KL, Mullins JJ, Mitchell KD. Enhancement of renin and prorenin receptor in the collecting ducts of Cyp1a1-Ren2 rats contribute to development and progression of malignant hypertension. Am J Physiol Renal Physiol In press.
31. Prieto-Carrasquero MC, Botros FT, Kobori H, Navar LG. Collecting duct renin: a major player in angiotensin II-dependent hypertension. J Am Soc Hypertens 3: 96-104, 2009.
32. Prieto-Carrasquero MC, Harrison-Bernard LM, Kobori H, Ozawa Y, Hering-Smith KS, Hamm LL, Navar LG. Enhancement of collecting duct renin in angiotensin II-dependent hypertensive rats. Hypertension 44: 223-229, 2004.
33. Prieto-Carrasquero MC, Kobori H, Ozawa Y, Gutierrez A, Seth D, Navar LG. AT1 receptor-mediated enhancement of collecting duct renin in angiotensin II-dependent hypertensive rats. Am J Physiol Renal Physiol 289: F632-F637, 2005.
34. Prieto-Carrasquero MC, Botros FT, Pagan J, Kobori H, Seth DM, Casarini DE, Navar LG. Collecting duct renin is upregulated in both kidneys of 2-kidney, 1-clip Goldblatt hypertensive rats. Hypertension 51: 1590-1596, 2008.
35. Redublo Quinto BM, Camargo de Andrade MC, Ronchi FA, Santos EL, ves Correa SA, Shimuta SI, Pesquero JB, Mortara RA, Casarini DE. Expression of angiotensin I-converting enzymes and bradykinin B2 receptors in mouse inner medullary-collecting duct cells. Int Immunopharmacol 8: 254-260, 2008.
36. Rohrwasser A, Morgan T, Dillon HF, Zhao L, Callaway CW, Hillas E, Zhang S, Cheng T, Inagami T, Ward K, Terreros DA, Lalouel JM. Elements of a paracrine tubular renin-angiotensin system along the entire nephron. Hypertension 34: 1265-1274, 1999.
37. Schunkert H, Ingelfinger JR, Jacob H, Jackson B, Bouyounes B, Dzau VJ. Reciprocal feedback regulation of kidney angiotensinogen and renin mRNA expressions by angiotensin II. Am J Physiol Endocrinol Metab 263: E863-E869, 1992.
38. Shao W, Seth DM, Navar LG. Augmentation of endogenous intrarenal angiotensin II levels in Val5-ANG II-infused rats. Am J Physiol Renal Physiol 296: F1067-F1071, 2009.
39. Taugner R, Hackenthal E, Inagami T, Nobiling R, Poulsen K. Vascular and tubular renin in the kidneys of mice. Histochemistry 75: 473-484, 1982.
40. Von Thun AM, Vari RC, El-Dahr SS, Navar LG. Augmentation of intrarenal angiotensin II levels by chronic angiotensin II infusion. Am J Physiol Renal Fluid Electrolyte Physiol 266: F120-F128, 1994.
41. Zhao D, Seth DM, Navar LG. Enhanced distal nephron sodium reabsorption in chronic angiotensin II-infused mice. Hypertension 54: 120-126, 2009.
42. Zou L, Imig JD, Von Thun AM, Hymel A, Ono H, Navar LG. Receptor-mediated intrarenal ANG II augmentation in ANG II-infused rats. Hypertension 28: 669-677, 1996.