-
1
-
-
0038053724
-
A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin i to angiotensin 1-9
-
Donoghue M, Hsieh F, Baronas E, Godbout K, Gosselin M, Stagliano N, Donovan M, Woolf B, Robison K, Jeyaseelan R, Breitbart RE, Acton S. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res. 2000;87:E1-E9.
-
(2000)
Circ Res
, vol.87
-
-
Donoghue, M.1
Hsieh, F.2
Baronas, E.3
Godbout, K.4
Gosselin, M.5
Stagliano, N.6
Donovan, M.7
Woolf, B.8
Robison, K.9
Jeyaseelan, R.10
Breitbart, R.E.11
Acton, S.12
-
2
-
-
0034721906
-
A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase
-
Tipnis SR, Hooper NM, Hyde R, Karran E, Christie G, Turner AJ. A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J Biol Chem. 2000;275:33238-33243.
-
(2000)
J Biol Chem
, vol.275
, pp. 33238-33243
-
-
Tipnis, S.R.1
Hooper, N.M.2
Hyde, R.3
Karran, E.4
Christie, G.5
Turner, A.J.6
-
3
-
-
20444407675
-
Organ-specific distribution of ACE2 mRNA and correlating peptidase activity in rodents
-
Gembardt F, Sterner-Kock A, Imboden H, Spalteholz M, Reibitz F, Schultheiss HP, Siems WE, Walther T. Organ-specific distribution of ACE2 mRNA and correlating peptidase activity in rodents. Peptides. 2005;26:1270-1277.
-
(2005)
Peptides
, vol.26
, pp. 1270-1277
-
-
Gembardt, F.1
Sterner-Kock, A.2
Imboden, H.3
Spalteholz, M.4
Reibitz, F.5
Schultheiss, H.P.6
Siems, W.E.7
Walther, T.8
-
4
-
-
0037142101
-
An-giotensin-converting enzyme 2 is an essential regulator of heart function
-
Crackower MA, Sarao R, Oudit GY, Yagil C, Kozieradzki I, Scanga SE, Oliveira-dos-Santos AJ, da CJ, Zhang L, Pei Y, Scholey J, Ferrario CM, Manoukian AS, Chappell MC, Backx PH, Yagil Y, Penninger JM. An-giotensin-converting enzyme 2 is an essential regulator of heart function. Nature. 2002;417:822-828.
-
(2002)
Nature
, vol.417
, pp. 822-828
-
-
Crackower, M.A.1
Sarao, R.2
Oudit, G.Y.3
Yagil, C.4
Kozieradzki, I.5
Scanga, S.E.6
Oliveira-Dos-Santos, A.J.7
Da Cj Zhang, L.8
Pei, Y.9
Scholey, J.10
Ferrario, C.M.11
Manoukian, A.S.12
Chappell, M.C.13
Backx, P.H.14
Yagil, Y.15
Penninger, J.M.16
-
5
-
-
33746724157
-
Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice
-
Gurley SB, Allred A, Le TH, Griffiths R, Mao L, Philip N, Haystead TA, Donoghue M, Breitbart RE, Acton SL, Rockman HA, Coffman TM. Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice. J Clin Invest. 2006;116:2218-2225.
-
(2006)
J Clin Invest
, vol.116
, pp. 2218-2225
-
-
Gurley, S.B.1
Allred, A.2
Le Th Griffiths, R.3
Mao, L.4
Philip, N.5
Haystead, T.A.6
Donoghue, M.7
Breitbart, R.E.8
Acton, S.L.9
Rockman, H.A.10
Coffman, T.M.11
-
6
-
-
0035941213
-
Use of a biological peptide pump to study chronic peptide hormone action in transgenic mice. Direct and indirect effects of angiotensin II on the heart
-
van Kats JP, Methot D, Paradis P, Silversides DW, Reudelhuber TL. Use of a biological peptide pump to study chronic peptide hormone action in transgenic mice. Direct and indirect effects of angiotensin II on the heart. J Biol Chem. 2001;276:44012-44017.
-
(2001)
J Biol Chem
, vol.276
, pp. 44012-44017
-
-
Van Kats, J.P.1
Methot, D.2
Paradis, P.3
Silversides, D.W.4
Reudelhuber, T.L.5
-
7
-
-
0037462643
-
Brain-specific restoration of angiotensin II corrects renal defects seen in angiotensinogen-deficient mice
-
Lochard N, Silversides DW, van Kats JP, Mercure C, Reudelhuber TL. Brain-specific restoration of angiotensin II corrects renal defects seen in angiotensinogen-deficient mice. J Biol Chem. 2003;278:2184-2189.
-
(2003)
J Biol Chem
, vol.278
, pp. 2184-2189
-
-
Lochard, N.1
Silversides, D.W.2
Van Kats, J.P.3
Mercure, C.4
Reudelhuber, T.L.5
-
8
-
-
3042723695
-
Expression of an angiotensin-(1-7)-producing fusion protein produces cardioprotective effects in rats
-
Santos RA, Ferreira AJ, Nadu AP, Braga AN, de Almeida AP, Campagnole-Santos MJ, Baltatu O, Iliescu R, Reudelhuber TL, Bader M. Expression of an angiotensin-(1-7)-producing fusion protein produces cardioprotective effects in rats. Physiol Genomics. 2004;17:292-299.
-
(2004)
Physiol Genomics
, vol.17
, pp. 292-299
-
-
Santos, R.A.1
Ferreira, A.J.2
Nadu, A.P.3
Braga, A.N.4
De Almeida, A.P.5
Campagnole-Santos, M.J.6
Baltatu, O.7
Iliescu, R.8
Reudelhuber, T.L.9
Bader, M.10
-
9
-
-
0028287449
-
Plasma angiotensin(1-7) immunoreactivity is increased by salt load, water deprivation, and hemorrhage
-
Botelho LM, Block CH, Khosla MC, Santos RA. Plasma angiotensin(1-7) immunoreactivity is increased by salt load, water deprivation, and hemorrhage. Peptides. 1994;15:723-729.
-
(1994)
Peptides
, vol.15
, pp. 723-729
-
-
Botelho, L.M.1
Block, C.H.2
Khosla, M.C.3
Santos, R.A.4
-
10
-
-
0024723470
-
Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. Am Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocar-diograms
-
Schiller NB, Shah PM, Crawford M, DeMaria A, Devereux R, Feigenbaum H, Gutgesell H, Reichek N, Sahn D, Schnittger I. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. Am Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocar-diograms. J Am Soc Echocardiogr. 1989;2:358-367.
-
(1989)
J Am Soc Echocardiogr
, vol.2
, pp. 358-367
-
-
Schiller, N.B.1
Shah, P.M.2
Crawford, M.3
Demaria, A.4
Devereux, R.5
Feigenbaum, H.6
Gutgesell, H.7
Reichek, N.8
Sahn, D.9
Schnittger, I.10
-
11
-
-
15744384153
-
Angiotensin II-dependent chronic hypertension and cardiac hypertrophy are unaffected by gp91phox-containing NADPH oxidase
-
Touyz RM, Mercure C, He Y, Javeshghani D, Yao G, Callera GE, Yogi A, Lochard N, Reudelhuber TL. Angiotensin II-dependent chronic hypertension and cardiac hypertrophy are unaffected by gp91phox-containing NADPH oxidase. Hypertension. 2005;45:530-537.
-
(2005)
Hypertension
, vol.45
, pp. 530-537
-
-
Touyz, R.M.1
Mercure, C.2
He, Y.3
Javeshghani, D.4
Yao, G.5
Callera, G.E.6
Yogi, A.7
Lochard, N.8
Reudelhuber, T.L.9
-
12
-
-
0037108204
-
Inhibition of PTPs by H(2)O(2) regulates the activation of distinct MAPK pathways
-
Lee K, Esselman WJ. Inhibition of PTPs by H(2)O(2) regulates the activation of distinct MAPK pathways. Free Radic Biol Med. 2002;33:1121-1132.
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 1121-1132
-
-
Lee, K.1
Esselman, W.J.2
-
13
-
-
0026342911
-
Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice
-
Subramaniam A, Jones WK, Gulick J, Wert S, Neumann J, Robbins J. Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice. J Biol Chem. 1991;266:24613-24620.
-
(1991)
J Biol Chem
, vol.266
, pp. 24613-24620
-
-
Subramaniam, A.1
Jones, W.K.2
Gulick, J.3
Wert, S.4
Neumann, J.5
Robbins, J.6
-
14
-
-
28144445338
-
Advances in biochemical and functional roles of angiotensin-converting enzyme 2 and angiotensin-(1-7) in regulation of cardiovascular function
-
Ferrario CM, Trask AJ, Jessup JA. Advances in biochemical and functional roles of angiotensin-converting enzyme 2 and angiotensin-(1-7) in regulation of cardiovascular function. Am J Physiol Heart Circ Physiol. 2005;289:H2281-H2290.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
-
-
Ferrario, C.M.1
Trask, A.J.2
Jessup, J.A.3
-
15
-
-
0347381135
-
Ras Akt and mechanotransduction in the cardiac myocyte
-
Sugden PH. Ras, Akt, and mechanotransduction in the cardiac myocyte. Circ Res. 2003;93:1179-1192.
-
(2003)
Circ Res
, vol.93
, pp. 1179-1192
-
-
Sugden, P.H.1
-
16
-
-
0032563677
-
"stress-responsive" mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium
-
Sugden PH, Clerk A. "Stress-responsive" mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium. Circ Res. 1998;83:345-352.
-
(1998)
Circ Res
, vol.83
, pp. 345-352
-
-
Sugden, P.H.1
Clerk, A.2
-
17
-
-
33748323383
-
Regulation of cardiac hypertrophy by intra-cellular signalling pathways
-
Heineke J, Molkentin JD. Regulation of cardiac hypertrophy by intra-cellular signalling pathways. Nat Rev Mol Cell Biol. 2006;7:589-600.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 589-600
-
-
Heineke, J.1
Molkentin, J.D.2
-
18
-
-
10744223104
-
Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins
-
Donoghue M, Wakimoto H, Maguire CT, Acton S, Hales P, Stagliano N, Fairchild-Huntress V, Xu J, Lorenz JN, Kadambi V, Berul CI, Breitbart RE. Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins. J Mol Cell Cardiol. 2003;35:1043-1053.
-
(2003)
J Mol Cell Cardiol
, vol.35
, pp. 1043-1053
-
-
Donoghue, M.1
Wakimoto, H.2
Maguire, C.T.3
Acton, S.4
Hales, P.5
Stagliano, N.6
Fairchild-Huntress, V.7
Xu, J.8
Lorenz, J.N.9
Kadambi, V.10
Berul, C.I.11
Breitbart, R.E.12
-
19
-
-
2942516608
-
Angiotensin deficiency in mice leads to dilated cardiomyopathy
-
Walther T, Steendijk P, Westermann D, Hohmann C, Schulze K, Heringer-Walther S, Schultheiss HP, Tschope C. Angiotensin deficiency in mice leads to dilated cardiomyopathy. Eur J Pharmacol. 2004;493:161-165.
-
(2004)
Eur J Pharmacol
, vol.493
, pp. 161-165
-
-
Walther, T.1
Steendijk, P.2
Westermann, D.3
Hohmann, C.4
Schulze, K.5
Heringer-Walther, S.6
Schultheiss, H.P.7
Tschope, C.8
-
20
-
-
33646161714
-
Impairment of in vitro and in vivo heart function in angioten-sin-(1-7) receptor MAS knockout mice
-
Santos RA, Castro CH, Gava E, Pinheiro SV, Almeida AP, Paula RD, Cruz JS, Ramos AS, Rosa KT, Irigoyen MC, Bader M, Alenina N, Kitten GT, Ferreira AJ. Impairment of in vitro and in vivo heart function in angioten-sin-(1-7) receptor MAS knockout mice. Hypertension. 2006;47:996-1002.
-
(2006)
Hypertension
, vol.47
, pp. 996-1002
-
-
Santos, R.A.1
Castro, C.H.2
Gava, E.3
Pinheiro, S.V.4
Almeida, A.P.5
Paula, R.D.6
Cruz, J.S.7
Ramos, A.S.8
Rosa, K.T.9
Irigoyen, M.C.10
Bader, M.11
Alenina, N.12
Kitten, G.T.13
Ferreira, A.J.14
-
21
-
-
25444473110
-
Angiotensin-(1-7) inhibits growth of cardiac myocytes through activation of the mas receptor
-
Tallant EA, Ferrario CM, Gallagher PE. Angiotensin-(1-7) inhibits growth of cardiac myocytes through activation of the mas receptor. Am J Physiol Heart Circ Physiol. 2005;289:H1560-H1566.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
-
-
Tallant, E.A.1
Ferrario, C.M.2
Gallagher, P.E.3
-
22
-
-
0032745497
-
Communication between myocytes and fibroblasts in cardiac remodeling in angiotensin chimeric mice
-
Matsusaka T, Katori H, Inagami T, Fogo A, Ichikawa I. Communication between myocytes and fibroblasts in cardiac remodeling in angiotensin chimeric mice. J Clin Invest. 1999;103:1451-1458.
-
(1999)
J Clin Invest
, vol.103
, pp. 1451-1458
-
-
Matsusaka, T.1
Katori, H.2
Inagami, T.3
Fogo, A.4
Ichikawa, I.5
-
23
-
-
0346850854
-
Expression of constitutively active guanylate cyclase in cardiomyocytes inhibits the hypertrophic effects of isoproterenol and aortic constriction on mouse hearts
-
Zahabi A, Picard S, Fortin N, Reudelhuber TL, Deschepper CF. Expression of constitutively active guanylate cyclase in cardiomyocytes inhibits the hypertrophic effects of isoproterenol and aortic constriction on mouse hearts. J Biol Chem. 2003;278:47694-47699.
-
(2003)
J Biol Chem
, vol.278
, pp. 47694-47699
-
-
Zahabi, A.1
Picard, S.2
Fortin, N.3
Reudelhuber, T.L.4
Deschepper, C.F.5
-
24
-
-
0042266791
-
Focal adhesion kinase is activated and mediates the early hypertrophic response to stretch in cardiac myocytes
-
Torsoni AS, Constancio SS, Nadruz W Jr, Hanks SK, Franchini KG. Focal adhesion kinase is activated and mediates the early hypertrophic response to stretch in cardiac myocytes. Circ Res. 2003;93:140-147.
-
(2003)
Circ Res
, vol.93
, pp. 140-147
-
-
Torsoni, A.S.1
Constancio, S.S.2
Nadruz Jr.W3
Hanks, S.K.4
Franchini, K.G.5
-
25
-
-
40849133772
-
Role of transforming growth factor-beta super-family signaling pathways in human disease
-
Gordon KJ, Blobe GC. Role of transforming growth factor-beta super-family signaling pathways in human disease. Biochim Biophys Acta. 2008;1782:197-228.
-
(2008)
Biochim Biophys Acta
, vol.1782
, pp. 197-228
-
-
Gordon, K.J.1
Blobe, G.C.2
-
26
-
-
35348921181
-
Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo
-
Purcell NH, Wilkins BJ, York A, Saba-El-Leil MK, Meloche S, Robbins J, Molkentin JD. Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo. Proc Natl Acad Sci U S A. 2007;104:14074-14079.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 14074-14079
-
-
Purcell, N.H.1
Wilkins, B.J.2
York, A.3
Saba-El-Leil, M.K.4
Meloche, S.5
Robbins, J.6
Molkentin, J.D.7
-
27
-
-
20244388129
-
G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor
-
Kostenis E, Milligan G, Christopoulos A, Sanchez-Ferrer CF, Heringer-Walther S, Sexton PM, Gembardt F, Kellett E, Martini L, Vanderheyden P, Schultheiss HP, Walther T. G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor. Circulation. 2005;111: 1806-1813.
-
(2005)
Circulation
, vol.111
, pp. 1806-1813
-
-
Kostenis, E.1
Milligan, G.2
Christopoulos, A.3
Sanchez-Ferrer, C.F.4
Heringer-Walther, S.5
Sexton, P.M.6
Gembardt, F.7
Kellett, E.8
Martini, L.9
Vanderheyden, P.10
Schultheiss, H.P.11
Walther, T.12
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