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Volumn 28, Issue 12, 2013, Pages 2977-2982

The intrarenal renin-angiotensin system: Does it exist? Implications from a recent study in renal angiotensin-converting enzyme knockout mice

Author keywords

ACE inhibitor; Angiotensin; Chymase; Diabetes; Hypertension; Renin

Indexed keywords

ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSINOGEN; BRADYKININ; DIPEPTIDYL CARBOXYPEPTIDASE; NITRIC OXIDE SYNTHASE INHIBITOR; PRORENIN;

EID: 84890022318     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gft333     Document Type: Review
Times cited : (14)

References (33)
  • 1
    • 0035190220 scopus 로고    scopus 로고
    • Intrarenal angiotensin II: Interstitial and cellular levels and site of production
    • Van Kats JP, Schalekamp MADH, Verdouw PD et al. Intrarenal angiotensin II: interstitial and cellular levels and site of production. Kidney Int 2001; 60: 2311-2317
    • (2001) Kidney Int , vol.60 , pp. 2311-2317
    • Van Kats, J.P.1    Schalekamp, M.A.D.H.2    Verdouw, P.D.3
  • 2
    • 0030794448 scopus 로고    scopus 로고
    • Angiotensin II type 1 (AT1) receptor-mediated accumulation of angiotensin II in tissues and its intracellular half-life in vivo
    • Van Kats JP, de Lannoy LM, Danser AHJ et al. Angiotensin II type 1 (AT1) receptor-mediated accumulation of angiotensin II in tissues and its intracellular half-life in vivo. Hypertension 1997; 30: 42-49
    • (1997) Hypertension , vol.30 , pp. 42-49
    • Van Kats, J.P.1    De Lannoy, L.M.2    Danser, A.H.J.3
  • 3
    • 0035066863 scopus 로고    scopus 로고
    • Subcellular localization of angiotensin II in kidney and adrenal
    • Van Kats JP, van Meegen JR, Verdouw PD et al. Subcellular localization of angiotensin II in kidney and adrenal. J Hypertens 2001; 19: 583-589
    • (2001) J Hypertens , vol.19 , pp. 583-589
    • Van Kats, J.P.1    Van Meegen, J.R.2    Verdouw, P.D.3
  • 4
    • 77952368115 scopus 로고    scopus 로고
    • Cardiac phenotype and angiotensin II levels in AT1a, AT1b and AT2 receptor single, double and triple knockouts
    • Van Esch JHM, Gembardt F, Sterner-Kock A et al. Cardiac phenotype and angiotensin II levels in AT1a, AT1b and AT2 receptor single, double and triple knockouts. . Cardiovasc Res 2010; 86: 401-409
    • (2010) . Cardiovasc Res , vol.86 , pp. 401-409
    • Van Esch, J.H.M.1    Gembardt, F.2    Sterner-Kock, A.3
  • 6
    • 83155180323 scopus 로고    scopus 로고
    • Renin-and prorenininduced effects in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor: Does (pro)renin-(pro)renin receptor interaction actually occur?
    • Batenburg WW, Lu X, Leijten F et al. Renin-and prorenininduced effects in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor: does (pro)renin-(pro)renin receptor interaction actually occur? Hypertension 2011; 58: 1111-1119
    • (2011) Hypertension , vol.58 , pp. 1111-1119
    • Batenburg, W.W.1    Lu, X.2    Leijten, F.3
  • 7
    • 0032709804 scopus 로고    scopus 로고
    • The paradox of the lowrenin state in diabetic nephropathy
    • Price DA, Porter LE, Gordon M et al. The paradox of the lowrenin state in diabetic nephropathy. J Am Soc Nephrol 1999; 10: 2382-2391
    • (1999) J Am Soc Nephrol , vol.10 , pp. 2382-2391
    • Price, D.A.1    Porter, L.E.2    Gordon, M.3
  • 8
    • 3543026852 scopus 로고    scopus 로고
    • Enhancement of collecting duct renin in angiotensin II-dependent hypertensive rats
    • Prieto-Carrasquero MC, Harrison-Bernard LM, Kobori H et al. Enhancement of collecting duct renin in angiotensin II-dependent hypertensive rats. Hypertension 2004; 44: 223-229
    • (2004) Hypertension , vol.44 , pp. 223-229
    • Prieto-Carrasquero, M.C.1    Harrison-Bernard, L.M.2    Kobori, H.3
  • 9
    • 45849143635 scopus 로고    scopus 로고
    • The collecting duct is the major source of prorenin in diabetes
    • Kang JJ, Toma I, Sipos A et al. The collecting duct is the major source of prorenin in diabetes. Hypertension 2008; 51: 1597-1604
    • (2008) Hypertension , vol.51 , pp. 1597-1604
    • Kang, J.J.1    Toma, I.2    Sipos, A.3
  • 10
    • 0021889169 scopus 로고
    • Increased plasma inactive renin in diabetes mellitus. A marker of microvascular complications
    • Luetscher JA, Kraemer FB, Wilson DM et al. Increased plasma inactive renin in diabetes mellitus. A marker of microvascular complications. N Engl J Med 1985; 312: 1412-1417
    • (1985) N Engl J Med , vol.312 , pp. 1412-1417
    • Luetscher, J.A.1    Kraemer, F.B.2    Wilson, D.M.3
  • 11
    • 0032787740 scopus 로고    scopus 로고
    • Increase in serum prorenin precedes onset of microalbuminuria in patients with insulindependent diabetes mellitus
    • Deinum J, Ronn B, Mathiesen E et al. Increase in serum prorenin precedes onset of microalbuminuria in patients with insulindependent diabetes mellitus. Diabetologia 1999; 42: 1006-1010
    • (1999) Diabetologia , vol.42 , pp. 1006-1010
    • Deinum, J.1    Ronn, B.2    Mathiesen, E.3
  • 12
    • 0024495446 scopus 로고
    • Renin, prorenin, and immunoreactive renin in vitreous fluid from eyes with and without diabetic retinopathy
    • Danser AHJ, van den Dorpel MA, Deinum J et al. Renin, prorenin, and immunoreactive renin in vitreous fluid from eyes with and without diabetic retinopathy. J Clin Endocrinol Metab 1989; 68: 160-167
    • (1989) J Clin Endocrinol Metab , vol.68 , pp. 160-167
    • Danser, A.H.J.1    Van Den Dorpel, M.A.2    Deinum, J.3
  • 13
    • 80054095021 scopus 로고    scopus 로고
    • Urinary renin, but not angiotensinogen or aldosterone, reflects the renal renin-angiotensin-aldosterone system activity and the efficacy of renin-angiotensin-aldosterone system blockade in the kidney
    • Van den Heuvel M, Batenburg WW, Jainandunsing S et al. Urinary renin, but not angiotensinogen or aldosterone, reflects the renal renin-angiotensin- aldosterone system activity and the efficacy of renin-angiotensin-aldosterone system blockade in the kidney. J Hypertens 2011; 29: 2147-2155
    • (2011) J Hypertens , vol.29 , pp. 2147-2155
    • Van Den Heuvel, M.1    Batenburg, W.W.2    Jainandunsing, S.3
  • 14
    • 0031009958 scopus 로고    scopus 로고
    • Renin-angiotensin system components in the interstitial fluid of the isolated perfused rat heart. Local production of angiotensin i
    • De Lannoy LM, Danser AHJ, van Kats JP et al. Renin-angiotensin system components in the interstitial fluid of the isolated perfused rat heart. Local production of angiotensin I. Hypertension 1997; 29: 1240-1251
    • (1997) Hypertension , vol.29 , pp. 1240-1251
    • De Lannoy, L.M.1    Danser, A.H.J.2    Van Kats, J.P.3
  • 15
    • 0036158053 scopus 로고    scopus 로고
    • Urinary excretion of angiotensinogen reflects intrarenal angiotensinogen production
    • Kobori H, Harrison-Bernard LM, Navar LG. Urinary excretion of angiotensinogen reflects intrarenal angiotensinogen production. Kidney Int 2002; 61: 579-585
    • (2002) Kidney Int , vol.61 , pp. 579-585
    • Kobori, H.1    Harrison-Bernard, L.M.2    Navar, L.G.3
  • 16
    • 2342527267 scopus 로고    scopus 로고
    • AT1 receptor mediated augmentation of intrarenal angiotensinogen in angiotensin II-dependent hypertension
    • Kobori H, Prieto-Carrasquero MC, Ozawa Y et al. AT1 receptor mediated augmentation of intrarenal angiotensinogen in angiotensin II-dependent hypertension. Hypertension 2004; 43: 1126-1132
    • (2004) Hypertension , vol.43 , pp. 1126-1132
    • Kobori, H.1    Prieto-Carrasquero, M.C.2    Ozawa, Y.3
  • 17
    • 59849122906 scopus 로고    scopus 로고
    • Angiotensinconverting enzyme-derived angiotensin II formation during angiotensin II-induced hypertension
    • Gonzalez-Villalobos RA, Satou R, Seth DM et al. Angiotensinconverting enzyme-derived angiotensin II formation during angiotensin II-induced hypertension. Hypertension 2009; 53: 351-355
    • (2009) Hypertension , vol.53 , pp. 351-355
    • Gonzalez-Villalobos, R.A.1    Satou, R.2    Seth, D.M.3
  • 18
    • 0001595625 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme in non-neoplastic kidney diseases
    • Metzger R, Bohle RM, Pauls K et al. Angiotensin-converting enzyme in non-neoplastic kidney diseases. Kidney Int 1999; 56: 1442-1454
    • (1999) Kidney Int , vol.56 , pp. 1442-1454
    • Metzger, R.1    Bohle, R.M.2    Pauls, K.3
  • 19
    • 18344367831 scopus 로고    scopus 로고
    • Angiotensinogen and angiotensin-converting enzyme gene copy number and angiotensin and bradykinin peptide levels in mice
    • Alexiou T, Boon WM, Denton DA et al. Angiotensinogen and angiotensin-converting enzyme gene copy number and angiotensin and bradykinin peptide levels in mice. J Hypertens 2005; 23: 945-954
    • (2005) J Hypertens , vol.23 , pp. 945-954
    • Alexiou, T.1    Boon, W.M.2    Denton, D.A.3
  • 20
    • 0028152913 scopus 로고
    • Angiotensinogen-deficient mice with hypotension
    • Tanimoto K, Sugiyama F, Goto Y et al. Angiotensinogen-deficient mice with hypotension. J Biol Chem 1994; 269: 31334-31337.
    • (1994) J Biol Chem , vol.269 , pp. 31334-31337
    • Tanimoto, K.1    Sugiyama, F.2    Goto, Y.3
  • 21
    • 0031034417 scopus 로고    scopus 로고
    • Aberrant renal vascular morphology and renin expression in mutant mice lacking angiotensin-converting enzyme
    • Hilgers KF, Reddi V, Krege JH et al. Aberrant renal vascular morphology and renin expression in mutant mice lacking angiotensin-converting enzyme. Hypertension 1997; 29: 216-221
    • (1997) Hypertension , vol.29 , pp. 216-221
    • Hilgers, K.F.1    Reddi, V.2    Krege, J.H.3
  • 23
    • 84871606715 scopus 로고    scopus 로고
    • Lack of specificity of commercial antibodies leads to misidentification of angiotensin type 1 receptor protein
    • Herrera M, Sparks MA, Alfonso-Pecchio AR et al. Lack of specificity of commercial antibodies leads to misidentification of angiotensin type 1 receptor protein. Hypertension 2013; 61: 253-258
    • (2013) Hypertension , vol.61 , pp. 253-258
    • Herrera, M.1    Sparks, M.A.2    Alfonso-Pecchio, A.R.3
  • 24
    • 84856240947 scopus 로고    scopus 로고
    • Increased angiotensin IIinduced hypertension and inflammatory cytokines in mice lacking angiotensin-converting enzyme N domain activity
    • Ong FS, Lin CX, Campbell DJ et al. Increased angiotensin IIinduced hypertension and inflammatory cytokines in mice lacking angiotensin-converting enzyme N domain activity. Hypertension 2012; 59: 283-290
    • (2012) Hypertension , vol.59 , pp. 283-290
    • Ong, F.S.1    Lin, C.X.2    Campbell, D.J.3
  • 25
    • 47049093197 scopus 로고    scopus 로고
    • Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humans
    • Fisher NDL, Danser AHJ, Nussberger J et al. Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humans. Circulation 2008; 117: 3199-3205
    • (2008) Circulation , vol.117 , pp. 3199-3205
    • Fisher, N.D.L.1    Danser, A.H.J.2    Nussberger, J.3
  • 26
    • 0033498923 scopus 로고    scopus 로고
    • Cardiac interstitial fluid levels of angiotensin i and II in the pig
    • Schuijt MP, van Kats JP, de Zeeuw S et al. Cardiac interstitial fluid levels of angiotensin I and II in the pig. J Hypertens 1999; 17: 1885-1891
    • (1999) J Hypertens , vol.17 , pp. 1885-1891
    • Schuijt, M.P.1    Van Kats, J.P.2    De Zeeuw, S.3
  • 27
    • 0346099207 scopus 로고    scopus 로고
    • Role of metabolism and receptor responsiveness in the attenuated responses to angiotensin II in mice compared to rats
    • Cassis LA, Huang J, Gong MC et al. Role of metabolism and receptor responsiveness in the attenuated responses to angiotensin II in mice compared to rats. Regul Pept 2004; 117: 107-116
    • (2004) Regul Pept , vol.117 , pp. 107-116
    • Cassis, L.A.1    Huang, J.2    Gong, M.C.3
  • 28
    • 84863503716 scopus 로고    scopus 로고
    • Liver angiotensinogen is the primary source of renal angiotensin II
    • Matsusaka T, Niimura F, Shimizu A et al. Liver angiotensinogen is the primary source of renal angiotensin II. J Am Soc Nephrol 2012; 23: 1181-1189
    • (2012) J Am Soc Nephrol , vol.23 , pp. 1181-1189
    • Matsusaka, T.1    Niimura, F.2    Shimizu, A.3
  • 29
    • 19944427503 scopus 로고    scopus 로고
    • Selective angiotensin-converting enzyme C-domain inhibition is sufficient to prevent angiotensin I-induced vasoconstriction
    • Van Esch JH, Tom B, Dive V et al. Selective angiotensin-converting enzyme C-domain inhibition is sufficient to prevent angiotensin I-induced vasoconstriction. Hypertension 2005; 45: 120-125
    • (2005) Hypertension , vol.45 , pp. 120-125
    • Van Esch, J.H.1    Tom, B.2    Dive, V.3
  • 30
    • 38549119426 scopus 로고    scopus 로고
    • Angiotensinconverting enzyme C-terminal catalytic domain is the main site of angiotensin i cleavage in vivo
    • Fuchs S, Xiao HD, Hubert C et al. Angiotensinconverting enzyme C-terminal catalytic domain is the main site of angiotensin I cleavage in vivo. Hypertension 2008; 51: 267-274
    • (2008) Hypertension , vol.51 , pp. 267-274
    • Fuchs, S.1    Xiao, H.D.2    Hubert, C.3
  • 31
    • 0035569026 scopus 로고    scopus 로고
    • Bradykinin potentiation by angiotensin-(1-7) and angiotensin-converting enzyme (ACE) inhibitors correlates with ACE C-and N-domain blockade
    • Tom B, de Vries R, Saxena PR et al. Bradykinin potentiation by angiotensin-(1-7) and angiotensin-converting enzyme (ACE) inhibitors correlates with ACE C-and N-domain blockade. Hypertension 2001; 38: 95-99
    • (2001) Hypertension , vol.38 , pp. 95-99
    • Tom, B.1    De Vries, R.2    Saxena, P.R.3
  • 32
    • 34547951696 scopus 로고    scopus 로고
    • Novel drugs targeting hypertension: Renin inhibitors
    • Danser AHJ. Novel drugs targeting hypertension: renin inhibitors. J Cardiovasc Pharmacol 2007; 50: 105-111
    • (2007) J Cardiovasc Pharmacol , vol.50 , pp. 105-111
    • Danser, A.H.J.1
  • 33
    • 64849107987 scopus 로고    scopus 로고
    • The impact of left ventricular assist device-induced left ventricular unloading on the myocardial renin-angiotensin-aldosterone system: Therapeutic consequences?
    • Klotz S, Burkhoff D, Garrelds IM et al. The impact of left ventricular assist device-induced left ventricular unloading on the myocardial renin-angiotensin-aldosterone system: therapeutic consequences? Eur Heart J 2009; 30: 805-812
    • (2009) Eur Heart J , vol.30 , pp. 805-812
    • Klotz, S.1    Burkhoff, D.2    Garrelds, I.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.