Transgenic mice expressing an intracellular fluorescent fusion of angiotensin II demonstrate renal thrombotic microangiopathy and elevated blood pressure

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 298, Issue 6, 2010, Pages

  Redding, K M ^a   Chen, B L ^a   Singh, A ^a   Re, R N ^a   Navar, L G ^a   Seth, D M ^a   Sigmund, C D ^b   Tang, W W ^c   Cook, J L ^a  

^a TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c OCHSNER CLINIC FOUNDATION   (United States)

Author keywords

Intracellular angiotensin; Intracrine; Renal microangiopathy; Transgenic

Indexed keywords

ANGIOTENSIN II; CYAN FLUORESCENT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; EMBRYO; FEMALE; FIBROBLAST; FLUORESCENCE; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GLOMERULUS CAPILLARY; HISTOPATHOLOGY; HYPERTENSION; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; KIDNEY; MALE; MICROTHROMBUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; RENAL THROMBOTIC MICROANGIOPATHY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYSTOLIC BLOOD PRESSURE; TELEMETRY; THROMBOTIC THROMBOCYTOPENIC PURPURA; TRANSGENE; TRANSGENIC MOUSE; WILD TYPE;

ANGIOTENSIN II; ANIMALS; BLOOD PRESSURE; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; FIBROBLASTS; GREEN FLUORESCENT PROTEINS; HYPERTENSION; KIDNEY; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RNA, MESSENGER; THROMBOTIC MICROANGIOPATHIES;

EID: 77952623456     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00027.2010     Document Type: Article

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