Anti-diabetic actions of glucagon-like peptide-1 on pancreatic beta-cells

Metabolism: Clinical and Experimental

Volumn 63, Issue 1, 2014, Pages 9-19

  Lee, Young Sun ^a   Jun, Hee Sook ^a,b  

^a Gachon University   (South Korea)

^b Gil Hospital   (South Korea)

Author keywords

Anti apoptosis; Incretin hormone; Pancreatic islet; Proliferation; Type 2 diabetes

Indexed keywords

DIPEPTIDYL PEPTIDASE IV INHIBITOR; EXENDIN 4; GASTRIN; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; LIRAGLUTIDE; PROGLUCAGON; SITAGLIPTIN; SOMATOSTATIN;

ANTIDIABETIC ACTIVITY; APOPTOSIS; APPETITE; CELL DAMAGE; CELL DIFFERENTIATION; CELL DIVISION; CELL PROLIFERATION; CELL PROTECTION; CELL REGENERATION; CELL SURVIVAL; CONTINUOUS INFUSION; DIABETES MELLITUS; DNA SYNTHESIS; ENDOPLASMIC RETICULUM STRESS; GLUCAGON RELEASE; GLUCONEOGENESIS; GLUCOSE TRANSPORT; HEART FUNCTION; HEART PROTECTION; HUMAN; INFLAMMATION; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; INSULIN SENSITIVITY; INSULIN SYNTHESIS; LIPOGENESIS; LIPOPROTEIN SECRETION; META ANALYSIS (TOPIC); NEUROPROTECTION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS CANCER; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PANCREATITIS; PRIORITY JOURNAL; PROTEIN SECRETION; REVIEW; SIGNAL TRANSDUCTION; STEATOSIS; STOMACH EMPTYING; STOMACH MOTILITY; THERMOGENESIS;

5′ AMP-ACTIVATED PROTEIN KINASE; AMPK; ANTI-APOPTOSIS; B-CELL LYMPHOMA-2; B-CELL LYMPHOMA-EXTRA LARGE; B-CELL TRANSLOCATION GENE 2; BAD; BCL-2; BCL-XL; BCL-XL/BCL2-ASSOCIATED DEATH PROMOTER HOMOLOG; BINDING IMMUNOGLOBULIN PROTEIN; BIP; BTG2; C/EBP; CAMP RESPONSE-BINDING PROTEIN; CCAAT/ENHANCER-BINDING PROTEIN; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR II; COUP-TFII; CREB; DIPEPTIDYL PEPTIDASE IV; DPP-IV; EGFR; ENDOPLASMIC RETICULUM; EPAC; EPIDERMAL GROWTH FACTOR RECEPTOR; ER; ERK; EXCHANGE PROTEIN ACTIVATED BY CAMP; EXTRACELLULAR SIGNAL REGULATED KINASE; FORKHEAD BOX; FOX; G-PROTEIN COUPLED RECEPTOR; GIP; GLICENTIN-RELATED POLYPEPTIDE; GLP; GLP-1 RECEPTOR; GLP-1R; GLUCAGON-LIKE PEPTIDE; GLUCOSE TRANSPORTER; GLUCOSE-DEPENDENT INSULINOTROPIC PEPTIDE; GLUT; GPR; GRPP; HEPATOCYTE NUCLEAR FACTOR; HNF; INCRETIN HORMONE; INSULIN RECEPTOR SUBSTRATE; INTERVENING PEPTIDE; IP; IRS; MAJOR PROGLUCAGON FRAGMENT; MAMMALIAN TARGET OF RAPAMYCIN; MAPK; MEK; MITOGEN-ACTIVATED PROTEIN KINASE; MITOGEN-ACTIVATED PROTEIN KINASE KINASE; MPGF; MTOR; NFAT; NOD; NONOBESE DIABETIC; NUCLEAR FACTOR OF ACTIVATED T-CELLS; P21-ACTIVATED KINASE; P90 RIBOSOMAL S6 KINASE; P90RSK; PAK; PANCREAS DUODENUM HOMEOBOX 1; PANCREATIC ISLET; PC; PCNA; PDX-1; PHOSPHATIDYLINOSITOL; PI; PK; PROHORMONE CONVERTASE; PROLIFERATING CELL NUCLEAR ANTIGEN; PROLIFERATION; PROTEIN KINASE; SAD; SOX; SREBP; SRY-RELATED HIGH MOBILITY GROUP BOX; STEROL REGULATORY ELEMENT BINDING PROTEIN; SYNAPSES OF AMPHIDS DEFECTIVE; TCF7L2; TGF; THIOREDOXIN-INTERACTING PROTEIN; TRANSCRIPTION FACTOR 7-LIKE 2 (T-CELL SPECIFIC, HMG-BOX); TRANSFORMING GROWTH FACTOR; TXNIP; TYPE 2 DIABETES;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; GLUCAGON-LIKE PEPTIDE 1; HUMANS; HYPOGLYCEMIC AGENTS; INCRETINS; INSULIN; INSULIN-SECRETING CELLS; SIGNAL TRANSDUCTION;

EID: 84890118673     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2013.09.010     Document Type: Review

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